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Daxx and HIRA go viral – How chromatin remodeling complexes affect DNA virus infection
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De-regulation of aurora kinases by oncogenic HPV; implications in cancer development and treatment
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Evaluating the performance of the Xpert HPV assay in detecting HPV positive cases in Morocco
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Clinical performance of the SureX PCR HPV test versus hybrid capture assays (DH2/careHPV) in primary cervical cancer screening
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The immunological heterogeneity of squamous cell carcinoma and adenocarcinoma of the uterine cervix: a systematic review
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Human cytomegalovirus UL82 promotes colorectal cancer cell proliferation through inhibiting the ubiquitination of OGDH via ANGPT2
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Precise identification of viral–host integration events in HPV-positive cervical cancers by targeted long-read sequencing
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Fusion oncoproteins acquire condensate propensity to initiate tumour formation
Fusion oncoproteins acquire condensate propensity to initiate tumour formation
Gene fusions are potent drivers of cancer, and nuclear condensates are known to have a role in transcription. By creating ...
Phase separation of ERCC6L2–CtIP regulates the extent of DNA end resection
Phase separation of ERCC6L2–CtIP regulates the extent of DNA end resection
The ataxia telangiectasia mutated (ATM) kinase orchestrates the early stages of DNA double-strand break repair by promotin...
RNA-binding proteins pull in chromatin loops
RNA-binding proteins pull in chromatin loops
During development as cells exit a pluripotent state, chromatin looping interactions are strengthened, but the mechanism f...
RNA-binding proteins mediate the maturation of chromatin topology during differentiation
RNA-binding proteins mediate the maturation of chromatin topology during differentiation
Topologically associating domains (TADs) and chromatin architectural loops impact promoter–enhancer interactions, wi...
Hbo1 and Msl complexes preserve differential compaction and H3K27me3 marking of active and inactive X chromosomes during mitosis
Hbo1 and Msl complexes preserve differential compaction and H3K27me3 marking of active and inactive X chromosomes during mitosis
In mammals, chromosome-wide regulatory mechanisms ensure a balance of X-linked gene dosage between males (XY) and females ...
CD160+CD8+ T cells for improved immunotherapy
CD160+CD8+ T cells for improved immunotherapy
A study now indicates that CD160⁺CD8⁺ T cells in patients with colorectal cancer modulate anti-tumour immune r...
CD160 dictates anti-PD-1 immunotherapy resistance by regulating CD8+ T cell exhaustion in colorectal cancer
CD160 dictates anti-PD-1 immunotherapy resistance by regulating CD8+ T cell exhaustion in colorectal cancer
The colon exhibits higher propensity for tumour development than ileum. However, the role of immune microenvironment diffe...
Durotaxis is a driver and potential therapeutic target in lung fibrosis and metastatic pancreatic cancer
Durotaxis is a driver and potential therapeutic target in lung fibrosis and metastatic pancreatic cancer
Durotaxis, cell migration along stiffness gradients, is linked to embryonic development, tissue repair and disease. Despit...
Temporal changes in sucrose phantoms for magnetic resonance imaging: effects of preparation temperatures
Temporal changes in sucrose phantoms for magnetic resonance imaging: effects of preparation temperatures
This study investigated the effects of preparation temperature and usage period on the relaxation times and apparent diffu...
Integrating MRI radiomics with novel fluid-based texture features (GLFZM) to predict atherothrombotic stroke risk
Integrating MRI radiomics with novel fluid-based texture features (GLFZM) to predict atherothrombotic stroke risk
The purpose of this study was to evaluate the predictive value of MRI-based texture features for assessing stroke risk fro...
Practical signal-to-noise ratio mapping using single clinical MR images
Practical signal-to-noise ratio mapping using single clinical MR images
Accurate signal-to-noise ratio (SNR) measurement is essential for evaluating image quality in magnetic resonance imaging (...
The comparison of MRI and CT protocol examination times for mechanical thrombectomy in acute ischemic stroke
The comparison of MRI and CT protocol examination times for mechanical thrombectomy in acute ischemic stroke
In acute ischemic stroke (AIS), where the shortest possible assessment is required to minimize time to mechanical thrombec...
GAN-MRI enhanced multi-organ MRI segmentation: a deep learning perspective
GAN-MRI enhanced multi-organ MRI segmentation: a deep learning perspective
Clinical magnetic resonance imaging (MRI) is a high-resolution tool widely used for detailed anatomical imaging. However, ...
Automatic segmentation of cone beam CT images using treatment planning CT images in patients with prostate cancer
Automatic segmentation of cone beam CT images using treatment planning CT images in patients with prostate cancer
Cone-beam computed tomography-based online adaptive radiotherapy (CBCT-based online ART) is currently used in clinical pra...
Effect of posture on renal volume: evaluation using multi-posture MRI
Effect of posture on renal volume: evaluation using multi-posture MRI
Measurement of renal volume is useful in the early detection and monitoring of renal disease. However, changes in renal vo...