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Multi-Omics Analysis Revealed That TAOK1 Can Be Used as a Prognostic Marker and Target in a Variety of Tumors, Especially in Cervical Cancer

TAOK1 serves as a promising prognostic biomarker and potential therapeutic target, especially for cervical cancer.

Oncotargets And Therapy

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Evaluation of Indoleamine 2,3-Dioxygenase (IDO) Expression in Osteosarcoma: Insights From a 10-Year Retrospective Cohort

We explore IDO expression in primary tumors and metastatic lesions among osteosarcoma patients, and its association with c...

Oncotargets And Therapy

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Clinical Impact of Osimertinib Dose Reduction in the First-Line Setting on EGFR Mutation-Positive Non-Small Cell Lung Cancer: A Retrospective Monocentric Study

The present, monocentric, retrospective study was conducted to identify the clinical course, efficacy, and safety of osime...

Oncotargets And Therapy

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Prognostic and Immunological Significance of NMNAT1 in Colorectal and Pan-Cancer Contexts

The aim of this study was to understand the prognostic and immunological significance of nicotinamide metabolism-related g...

Oncotargets And Therapy

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PCSK9 Manipulates Lipid Metabolism and the Immune Microenvironment in Cancer

Current state of knowledge regarding the role and underlying mechanisms of PCSK9 in tumorigenesis, progression, immune esc...

Oncotargets And Therapy

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Genomic Insights Into Early Relapsed Breast Cancer: Prognostic Challenges and Mutation Landscape

The clinicopathological & molecular characteristics of early recurrent metastatic breast cancer, its prognostic factor...

Oncotargets And Therapy

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Integrating Bulk and Single-Cell RNA Sequencing Data Reveals the Prognostic Significance of HOXC9-Related Immune Gene Signatures in Hepatocellular Carcinoma

HOXC9 is overexpressed in HCC and correlates with poor prognosis. The HRIG-based risk score model effectively evaluates th...

Oncotargets And Therapy

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Coumarins from Citrus aurantiifolia (Christm.) Swingle Peel with Potential Cytotoxic Activity Against MCF-7 Breast Cancer Cell Line: In Vitro and In Silico Studies

Potency of phenolic compounds from Citrus aurantiifolia (Christm.) Swingle peel as alternative treatment for breast cancer...

Oncotargets And Therapy

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Exploring Protein Expression Profiles in Lung Cancer Insufficient Microwave Ablation: Implications for Recurrence

Insufficient ablation can cause alterations in nucleotide metabolism, potentially leading to recurrence and metastasis.

Oncotargets And Therapy

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Waldenström Macroglobulinemia and Chronic Myelomonocytic Leukemia: Case Report and Literature Review

Reporting the case of a patient with Waldenström macroglobulinemia and chronic myelomonocytic leukemia who accepted h...

Oncotargets And Therapy

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Anti-Tumor Effects of Gilteritinib on FLT3 Mutations: Insights into Resistance Mechanisms in Ba/F3 Cell Models

Examining the inhibitory effects of gilteritinib, quizartinib and midostaurin on Ba/F3 cells with point mutations both in ...

Oncotargets And Therapy

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Neoadjuvant Targeted Therapy with Dacomitinib in a Stage IIIA Non-Small-Cell Lung Cancer Patient Harboring EGFR G719X: A Case Report

Dacomitinib use as neoadjuvant targeted therapy for EGFR positive advanced NSCLC & the application of molecular testin...

Oncotargets And Therapy

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Management of Regorafenib-Induced Hand-Foot Skin Reaction with Topical Chinese Medicine and Urea Ointment: A Case Report and Literature Review

Reviewing the clinical characteristics, pathogenesis, prevention and treatment strategies of hand-foot skin reaction cause...

Oncotargets And Therapy

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Integrated Genomic Analysis of Lung Squamous Cell Carcinoma Subtypes Characterized by Immunogenic Cell Death-Relevant Gene Signature

Identifying biomarkers associated with immunogenic cell death (ICD) in lung squamous cell carcinoma (LUSC), to develop tai...

Oncotargets And Therapy

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Combination of Aumolertinib, Dabrafenib, and Trametinib for a Patient with Advanced Lung Adenocarcinoma with an Osimertinib-Induced BRAF V600E Mutation: A Case Report

Reporting a case of a 36-year-old woman diagnosed with stage IV lung adenocarcinoma harboring the EGFR L858R mutation. Rea...

Oncotargets And Therapy

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Research Progress of GPR137 in Malignant Tumors: A Review

Reviewing the research progress of GPR137 in malignant tumors, highlighting the potential therapeutic significance of it a...

Oncotargets And Therapy

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Based on Soluble Immune Checkpoints Constructing a Random Survival Forest Model to Predict the Prognosis of Hepatitis B Virus-Associated Hepatocellular Carcinoma

We constructed a predictive model based on Soluble Immune Checkpoints to predict different survival times in HBV-HCC patie...

Oncotargets And Therapy

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Therapeutic Potential of Datopotamab Deruxtecan in the Treatment of Advanced Non-Small Cell Lung Cancer: Evidence to Date

Oncotargets And Therapy

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A Pyroptosis-Related LncRNA Signature for Predicting Prognosis, Immune Features and Drug Sensitivity in Ovarian Cancer

Oncotargets And Therapy

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Efficacy and Safety of Combined PD-1 Inhibitor with Induction Chemotherapy Followed by IMRT Plus Nimotuzumab in Locally Advanced Nasopharyngeal Carcinoma: A Retrospective Analysis [Corrigendum]

Corrigendum for the article Efficacy and Safety of Combined PD-1 Inhibitor With Induction Chemotherapy Followed by IMRT Pl...

Oncotargets And Therapy

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Integrating artificial intelligence with endoscopic ultrasound in the early detection of bilio-pancreatic lesions: Current advances and future prospects