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Derivatization of Sesamol with Stearic Acid Enhances Antibacterial Activity Against Mycoplasma pneumoniae–Induced Pneumonia in Mice
Derivatization of Sesamol with Stearic Acid Enhances Antibacterial Activity Against Mycoplasma pneumoniae–Induced Pneumonia in Mice
In the present study, we have designed and evaluated the antibacterial efficacy of stearic acid ester derivative of sesamo...
Inhibitory Effect of Nevadensin on Rheumatoid Fibroblast-Like Synoviocytes and Protective Effect in Complete Freund’s Adjuvant–Induced Rats for Benefit in Rheumatoid Arthritis
Inhibitory Effect of Nevadensin on Rheumatoid Fibroblast-Like Synoviocytes and Protective Effect in Complete Freund’s Adjuvant–Induced Rats for Benefit in Rheumatoid Arthritis
This research investigated the impact of nevadensin on inflammation, migration, and invasion in TNF-α-induced human r...
Mechanistic Role of Coumarins Useful in Mitigating Inflammatory Bowel Disease
Mechanistic Role of Coumarins Useful in Mitigating Inflammatory Bowel Disease
Crohn’s disease and ulcerative colitis are immune-mediated gastrointestinal disorders commonly referred to as inflam...
Unveiling the Molecular Mechanisms of Squalene Epoxidase Inhibition by Flavonoids from : Integrative Computational and Experimental Insights
Unveiling the Molecular Mechanisms of Squalene Epoxidase Inhibition by Flavonoids from : Integrative Computational and Experimental Insights
Squalene epoxidase is a key enzyme in the cholesterol biosynthesis pathway, making it a promising therapeutic target for c...
Protective Effects of Ginkgolide A Against Hydrogen Peroxide-Induced Oxidative Damage in Neuronal Cells and Its Mechanisms
Protective Effects of Ginkgolide A Against Hydrogen Peroxide-Induced Oxidative Damage in Neuronal Cells and Its Mechanisms
Oxidative stress in neuronal cells plays a crucial role in the onset and progression of Alzheimer's disease, making th...
Click Chemistry: An Outstanding Approach for Tuning Natural Products Bioactivities
Click Chemistry: An Outstanding Approach for Tuning Natural Products Bioactivities
Natural products derived from marine and terrestrial sources have emerged as a significant trend in drug discovery, owing ...
Screening of Plant Extracts from the Brazilian Atlantic Forest Reveals a Fraction Rich in Sesquiterpenes from as a Potential Antibacterial
Screening of Plant Extracts from the Brazilian Atlantic Forest Reveals a Fraction Rich in Sesquiterpenes from as a Potential Antibacterial
Extract-based libraries represent an underexplored resource for discovering compounds with potential for new drug developm...
Exploring Herbal Medicines for Human Infections Associated with Avian Influenza A Viruses: A Recent Outbreak
Exploring Herbal Medicines for Human Infections Associated with Avian Influenza A Viruses: A Recent Outbreak
Avian influenza viruses, particularly H9N2 and H5N1 viruses, pose serious health hazards to people since they can cause se...
Discovery and Cytotoxic Activity of -CF-Containing Pyrroloindolines
Discovery and Cytotoxic Activity of -CF-Containing Pyrroloindolines
Pyrroloindoline scaffolds are widely found in numerous biologically active and medicinally significant natural products. M...
Discovery of Novel Compounds from Hairy Roots with Anticarcinogenic and Cytoprotective Potential
Discovery of Novel Compounds from Hairy Roots with Anticarcinogenic and Cytoprotective Potential
Hairy root cultures of Linum leonii F.W. Schultz, Linaceae, are a valuable biotechnological source for producing bioactive...
Biological Effect of Alkaloid-Enriched Fractions and Reticuline from the on Promyelocyte HL-60 Cell Line
Biological Effect of Alkaloid-Enriched Fractions and Reticuline from the on Promyelocyte HL-60 Cell Line
Stephania dielsiana Y.C.Wu, Menispermaceae, is a traditional medicinal plant that, like the other species of the genus Ste...
Cnicin Regulates Bone Turnover Homeostasis in Rats with Ovariectomy-Induced Osteoporosis via RANKL/RANK/OPG Pathway
Cnicin Regulates Bone Turnover Homeostasis in Rats with Ovariectomy-Induced Osteoporosis via RANKL/RANK/OPG Pathway
Osteoporosis is a prevalent metabolic bone disease and a significant global health concern, ranking as the fourth major he...
Phytoconstituents of Extract and Fractions of Leaves Inhibit Nitric Oxide and Prostaglandins Inflammatory Mediators: , , and Chemical Profiling
Phytoconstituents of Extract and Fractions of Leaves Inhibit Nitric Oxide and Prostaglandins Inflammatory Mediators: , , and Chemical Profiling
The leaves of Macrosphyra longistyla (DC.) Hiern., Rubiaceae, are eaten as vegetables, in addition to the plant’s me...
Neuroprotective Potential of Lactic Acid Oligomers Derived from Heat-Killed HK-PS23
Neuroprotective Potential of Lactic Acid Oligomers Derived from Heat-Killed HK-PS23
Probiotics demonstrate beneficial effects in age-related cognitive decline. In this study, two lactic oligomers, namely 2-...
Chemometric Analysis of Species with Antileishmanial Activity Using Liquid Chromatography Coupled to Mass Spectrometry
Chemometric Analysis of Species with Antileishmanial Activity Using Liquid Chromatography Coupled to Mass Spectrometry
Leishmaniasis, caused by protozoa of the genus Leishmania, ranks as a major global health concern, as recognized by the Wo...
Bioactivity and Structure–Activity Relationship of Epigallocatechin and Epigallocatechin-3-Gallate Derivatives
Bioactivity and Structure–Activity Relationship of Epigallocatechin and Epigallocatechin-3-Gallate Derivatives
Extensive research has been conducted on epigallocatechin and epigallocatechin-3-gallate, common polyphenols found in gree...
Toxicological Profile of Corn Silk (): A Scoping Review
Toxicological Profile of Corn Silk (): A Scoping Review
Corn silk (Zea mays L., Poaceae) are functional extensions of the pistillate florets on the corn ear and have been widely ...
Photoprotective Potential of Mycosporine-Like Amino Acids in Red Algae (Rhodophyta) from San Andrés and Providencia Islands, Colombian Caribbean
Photoprotective Potential of Mycosporine-Like Amino Acids in Red Algae (Rhodophyta) from San Andrés and Providencia Islands, Colombian Caribbean
Ten samples of common red macroalgae (Rhodophyta) were collected from San Andrés and Providencia Islands (Colombia) t...
Preclinical Exploration of Newer Curcumin Analog (NSC 793122) as Potential Antiproliferative Agent
Preclinical Exploration of Newer Curcumin Analog (NSC 793122) as Potential Antiproliferative Agent
The synthesis of, 1-(3,5-bis((E)-4-hydroxy-3-methoxystyryl)-1H-pyrazol-1-yl)-2-((2,5-dimethoxyphenyl)amino)ethan-1-one (15...
Anxiolytic and Hypoglycemic Effect of Pectins from Galician Lemon Citrus Fruit on Adult Zebrafish (Danio rerio): An In Vivo and In Sílico Approach
Anxiolytic and Hypoglycemic Effect of Pectins from Galician Lemon Citrus Fruit on Adult Zebrafish (Danio rerio): An In Vivo and In Sílico Approach
Diabetes mellitus is a medical condition characterized by elevated blood glucose levels, known as hyperglycemia, which can...
Validation of a Fast LC-PDA Method for the Quantification of Cannabinoids in Commercial Tea Samples
Validation of a Fast LC-PDA Method for the Quantification of Cannabinoids in Commercial Tea Samples
Cannabis and cannabinoids are currently being used to treat a wide variety of medical conditions including, but not limite...
Antithrombotic Activity of the Steroids and ent-Kaurane Diterpenoids from Canna indica Rhizomes
Antithrombotic Activity of the Steroids and ent-Kaurane Diterpenoids from Canna indica Rhizomes
Canna indica L. Cannaceae, is a valuable plant used for the treatment of many conditions. However, the scientific evidence...
Antiviral Lectins of the Plant Family Amaryllidaceae
Antiviral Lectins of the Plant Family Amaryllidaceae
Plants have long served as a first line of defence against viral-borne diseases. Their chemical constituents have also aff...
Co-administration of Acarbose with Aqueous Extract of Root and Leaf of Sphenocentrum jollyanum Accelerates Wound Closure in Type 2 Diabetic Rats
Co-administration of Acarbose with Aqueous Extract of Root and Leaf of Sphenocentrum jollyanum Accelerates Wound Closure in Type 2 Diabetic Rats
Acarbose is an anti-hyperglycemic drug recognized as an inhibitor of carbohydrate-metabolizing enzymes. Hyperglycemia is a...
In Vitro Cytotoxic Potential of Ethanol Extract of Dictyopteris acrostichoides Against Human Cancer Cells
In Vitro Cytotoxic Potential of Ethanol Extract of Dictyopteris acrostichoides Against Human Cancer Cells
Ethanol extracts of Caulerpa racemose (Forsskål) J.Agardh, 1873, Dictyopteris acrostichoides (J.Agardh) Bornet, 1885,...
Combined Antifungal Effect of Plant Extracts and Itraconazole Against Candida albicans
Combined Antifungal Effect of Plant Extracts and Itraconazole Against Candida albicans
Combination therapy has emerged as an alternative to improve the efficacy of currently used antifungal therapy, as it can ...
Physicochemical Characterization and Biological Evaluation of Agaricus subrufescens Polysaccharides in Human Blood Cells
Physicochemical Characterization and Biological Evaluation of Agaricus subrufescens Polysaccharides in Human Blood Cells
The present work aimed to isolate and characterize the polysaccharides from Agaricus subrufescens Peck (1893), Agaricaceae...
Enhanced Bioactive Constituents and Improved AMPK and GLUT Dependent Glucose Uptake Effect of Thunbergia laurifolia Leaves by Calcium Chloride and Yeast Extract Elicitors in Postharvest Treatment
Enhanced Bioactive Constituents and Improved AMPK and GLUT Dependent Glucose Uptake Effect of Thunbergia laurifolia Leaves by Calcium Chloride and Yeast Extract Elicitors in Postharvest Treatment
Thunbergia laurifolia Lindl., Acanthaceae, leaves are a well-known commercialized infusion tea for health-supplem...
Spirulina and Thymoquinone Protect Against Methotrexate-Induced Hepatic Injury in Rats
Spirulina and Thymoquinone Protect Against Methotrexate-Induced Hepatic Injury in Rats
Methotrexate is a chemotherapy medication frequently used to treat various forms of cancer. The purpose of this research w...
Ursodeoxycholic Acid Enhances the Antibacterial Activity of Colistin by Inhibiting MCR-1
Ursodeoxycholic Acid Enhances the Antibacterial Activity of Colistin by Inhibiting MCR-1
Colistin is recognized as the “last line of defense” for the treatment of carbapenemase-producing “super...
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