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Semaglutide 2.4 mg versus Liraglutide 3 mg for the Treatment of Obesity in Greece: A Short-Term Cost-Effectiveness Analysis
Semaglutide 2.4 mg versus Liraglutide 3 mg for the Treatment of Obesity in Greece: A Short-Term Cost-Effectiveness Analysis
Obesity is a global health issue with significant economic implications for health systems. Pharmacotherapy, including sem...
Pricing for Multi-Indication Drugs in the Italian Regulatory Context
Pricing for Multi-Indication Drugs in the Italian Regulatory Context
The authorization of new therapeutic indications for drugs already reimbursed by the Italian National Health Service (NHS)...
From Vision to Reality: The EU’s Pharmaceutical Reforms and the Path to Improved Access
From Vision to Reality: The EU’s Pharmaceutical Reforms and the Path to Improved Access
Disparities in access to oncology medicines in European Union (EU) member states can impact patient outcomes profoundly, w...
Very Early Health Technology Assessment for Potential Predictive Biomarkers in the Treatment of Advanced Non-Small Cell Lung Cancer
Very Early Health Technology Assessment for Potential Predictive Biomarkers in the Treatment of Advanced Non-Small Cell Lung Cancer
Immune checkpoint inhibitor (ICI)-containing treatment is currently prescribed as first-line treatment for all patients wi...
Burden of Disease and Cost of Illness of Triple-Negative Breast Cancer in Portugal
Burden of Disease and Cost of Illness of Triple-Negative Breast Cancer in Portugal
Triple-negative breast cancer accounts for 15% of all breast cancer cases, and it has a lower survival rate and higher inc...
So Many Choices, So Little Value: Potential Savings from Selecting Cost-Effective Proton Pump Inhibitors
So Many Choices, So Little Value: Potential Savings from Selecting Cost-Effective Proton Pump Inhibitors
Given that Korea lacks measures to promote cost-effective prescribing, this study investigated the efficiency of prescribe...
Do We Understand Unmet Need? A Proposal to Use Length-Of-Life Equivalent (LOLE) as a Patient-Centric Measure of Unmet Need
Do We Understand Unmet Need? A Proposal to Use Length-Of-Life Equivalent (LOLE) as a Patient-Centric Measure of Unmet Need
Many decision-makers have emphasized the importance of leveraging patient experience data to measure unmet need. However, ...
Predicting Danish EQ-5D-5L Utilities Based on United Kingdom EQ-5D-3L Utilities for Use in Health Economic Models
Predicting Danish EQ-5D-5L Utilities Based on United Kingdom EQ-5D-3L Utilities for Use in Health Economic Models
Since 2021, the Danish Medicines Council recommends the use of the Danish EQ-5D-5L value set when estimating utilities. Th...
Costs and Complications of Respiratory Syncytial Virus and Acute Respiratory Infections in the Adult Population: Analysis of a German Claims Database
Costs and Complications of Respiratory Syncytial Virus and Acute Respiratory Infections in the Adult Population: Analysis of a German Claims Database
Respiratory syncytial virus (RSV) infections pose health and economic burdens to adults. Using claims data, we estimated R...
Cost-Effectiveness Analysis of Daridorexant for the Pharmacological Treatment of Chronic Insomnia Disorder in Adults
Cost-Effectiveness Analysis of Daridorexant for the Pharmacological Treatment of Chronic Insomnia Disorder in Adults
Daridorexant 50 mg is recommended for treating chronic insomnia in England, Wales (NICE, 2023) and Scotland (Scot...
Economic Burden of Acute Myeloid Leukemia in European Union: Results from a Systematic Review of Literature
Economic Burden of Acute Myeloid Leukemia in European Union: Results from a Systematic Review of Literature
Acute myeloid leukemia (AML) is a heterogenous malignancy whose management is associated with considerable healthcare reso...
Economic Evaluation of Patiromer in Patients with Concomitant Heart Failure and Chronic Kidney Disease in Italy
Economic Evaluation of Patiromer in Patients with Concomitant Heart Failure and Chronic Kidney Disease in Italy
Hyperkalaemia (HK), in patients with heart failure (HF) with and without chronic kidney disease (CKD), is potentially life...
Adjusting Health State Utility Values for Multiple Conditions: Real-World EQ-5D-3L Data Modeling in Brazil
Adjusting Health State Utility Values for Multiple Conditions: Real-World EQ-5D-3L Data Modeling in Brazil
Decision analytical models are typically included in health economic evaluations to represent clinical pathways and enable...
Cost-Effectiveness Analyses of Adolescent- and Young-Adult-Focused HIV Interventions Incorporating HIV Transmission: a Scoping Review of Modeling Methods and Proposed Guidance
Cost-Effectiveness Analyses of Adolescent- and Young-Adult-Focused HIV Interventions Incorporating HIV Transmission: a Scoping Review of Modeling Methods and Proposed Guidance
Adolescents and young adults (AYA) are disproportionately affected by human immunodeficiency virus (HIV) globally, with hi...
Exploratory Cost-Effectiveness of a Novel Bioprosthetic Valve for Surgical Aortic Valve Replacement in Spain
Exploratory Cost-Effectiveness of a Novel Bioprosthetic Valve for Surgical Aortic Valve Replacement in Spain
Limited information is available regarding the impact of valve choice for patients with aortic stenosis (AS) undergoing su...
An Enhanced Retention Strategy to Prevent the Vertical Transmission of HIV in Uganda: A Budget Impact Analysis
An Enhanced Retention Strategy to Prevent the Vertical Transmission of HIV in Uganda: A Budget Impact Analysis
Novel retention strategies have the potential to reduce vertical transmission of HIV and improve patient outcomes for wome...
Estimation of Lifetime Costs Among Insured Persons with HIV in the United States
Estimation of Lifetime Costs Among Insured Persons with HIV in the United States
With recent advances in human immunodeficiency virus (HIV) management and prevention, it is critical to understand the lif...
The Acceptance of Indirect Treatment Comparison Methods in Oncology by Health Technology Assessment Agencies in England, France, Germany, Italy, and Spain
The Acceptance of Indirect Treatment Comparison Methods in Oncology by Health Technology Assessment Agencies in England, France, Germany, Italy, and Spain
Randomized controlled trials (RCTs) are the gold standard when comparing treatment effectiveness, and Health Technology As...
Understanding the Natural History of Chronic Hepatitis D: Proposal of a Model for Cost-Effectiveness Studies
Understanding the Natural History of Chronic Hepatitis D: Proposal of a Model for Cost-Effectiveness Studies
As new therapeutic options become available, better understanding the potential impact of emerging therapies on clinical o...
Cost-Utility Analysis of Total Ankle Replacement Compared with Ankle Arthrodesis for Patients Aged 50–85 Years with End-Stage Ankle Osteoarthritis: The TARVA Study
Cost-Utility Analysis of Total Ankle Replacement Compared with Ankle Arthrodesis for Patients Aged 50–85 Years with End-Stage Ankle Osteoarthritis: The TARVA Study
Patients with end-stage ankle osteoarthritis suffer from reduced mobility and quality of life and the main surgical treatm...
Health State Utilities Associated with False-Positive Cancer Screening Results
Health State Utilities Associated with False-Positive Cancer Screening Results
Early cancer detection can significantly improve patient outcomes and reduce mortality rates. Novel cancer screening appro...
A Systematic Literature Review of Health-Related Quality of Life Outcomes and Associated Utility Values in Relapsed and/or Refractory Large B Cell Lymphoma
A Systematic Literature Review of Health-Related Quality of Life Outcomes and Associated Utility Values in Relapsed and/or Refractory Large B Cell Lymphoma
In this ever-expanding treatment landscape, there is a lack of consolidated health-related quality of life (HRQOL) outcome...
From Indication-Based Pricing to Blended Approach: Evidence on the Price and Reimbursement Negotiation in Italy
From Indication-Based Pricing to Blended Approach: Evidence on the Price and Reimbursement Negotiation in Italy
New indications for existing medicines are increasing over time. In most countries, drug pricing and reimbursement conditi...
Introducing Open Science in Teaching Health Economic Modelling
Introducing Open Science in Teaching Health Economic Modelling
Open Science is gaining ground in all research fields, including health economics and outcomes research (HEOR). However, t...
Cost-Effectiveness Analysis of Abrocitinib Compared with Other Systemic Treatments for Severe Atopic Dermatitis in Spain
Cost-Effectiveness Analysis of Abrocitinib Compared with Other Systemic Treatments for Severe Atopic Dermatitis in Spain
Atopic dermatitis (AD) is a chronic, inflammatory skin disease characterized by itchy, painful, and dry skin. Despite the ...
Cost-Effectiveness Analysis of Digital Breast Tomosynthesis Added to Synthetic Mammography in Breast Cancer Screening in Brazil
Cost-Effectiveness Analysis of Digital Breast Tomosynthesis Added to Synthetic Mammography in Breast Cancer Screening in Brazil
Literature meta-analysis results show that digital breast tomosynthesis (DBT) combined with synthesized two-dimensional (s...
An Economic Evaluation of a Streamlined Day-Case Atrial Fibrillation Ablation Protocol and Conventional Cryoballoon Ablation versus Antiarrhythmic Drugs in a UK Paroxysmal Atrial Fibrillation Population
An Economic Evaluation of a Streamlined Day-Case Atrial Fibrillation Ablation Protocol and Conventional Cryoballoon Ablation versus Antiarrhythmic Drugs in a UK Paroxysmal Atrial Fibrillation Population
Symptom control for atrial fibrillation can be achieved by catheter ablation or drug therapy. We assessed the cost effecti...
Health Economic Evaluations of Hemochromatosis Screening and Treatment: A Systematic Review
Health Economic Evaluations of Hemochromatosis Screening and Treatment: A Systematic Review
Hereditary hemochromatosis (HH) is an autosomal recessive disorder that leads to iron overload and multiorgan failure. The...
Cost Effectiveness of Endovascular Ultrasound Renal Denervation in Patients with Resistant Hypertension
Cost Effectiveness of Endovascular Ultrasound Renal Denervation in Patients with Resistant Hypertension
Resistant hypertension (rHTN) is defined as blood pressure (BP) of ≥ 140/90 mmHg despite treatment wi...
United States Value Set for the Functional Assessment of Cancer Therapy-General Eight Dimensions (FACT-8D), a Cancer-Specific Preference-Based Quality of Life Instrument
United States Value Set for the Functional Assessment of Cancer Therapy-General Eight Dimensions (FACT-8D), a Cancer-Specific Preference-Based Quality of Life Instrument
To develop a value set reflecting the United States (US) general population’s preferences for health states describe...
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