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Carer Health-Related Quality of Life: A Review of Modelling Considerations in National Institute for Health and Care Excellence Technology Appraisals (2000–2023)
Carer Health-Related Quality of Life: A Review of Modelling Considerations in National Institute for Health and Care Excellence Technology Appraisals (2000–2023)
Carer health-related quality of life (HRQoL) is increasingly used to support health technology assessments conducted by th...
Venetoclax in Combination with Obinutuzumab in Previously Untreated Fit Patients with Chronic Lymphocytic Leukemia: A Canadian Cost-Utility Analysis
Venetoclax in Combination with Obinutuzumab in Previously Untreated Fit Patients with Chronic Lymphocytic Leukemia: A Canadian Cost-Utility Analysis
Chronic lymphocytic leukemia (CLL) is the most common lymphoproliferative disorder diagnosed in Canada and is associated w...
Health Utility Decrement of Injection Treatment-Related Attributes Using Time Trade-Off Among Type 2 Diabetes Patients: A Vignette-Based Study
Health Utility Decrement of Injection Treatment-Related Attributes Using Time Trade-Off Among Type 2 Diabetes Patients: A Vignette-Based Study
To identify health utility decrements of injection treatment-related attributes among patients with type 2 diabetes mellit...
Cost-Effectiveness Analysis of Abrocitinib Compared with Dupilumab for Adolescents With Severe Atopic Dermatitis in Spain
Cost-Effectiveness Analysis of Abrocitinib Compared with Dupilumab for Adolescents With Severe Atopic Dermatitis in Spain
The adapted model consisted of a 52-week decision tree followed by a Markov approach, where patients remained for the rest...
Cost of Chronic Heart Failure Among Adult Europeans—A Systematic Literature Review
Cost of Chronic Heart Failure Among Adult Europeans—A Systematic Literature Review
Chronic heart failure (CHF) imposes a substantial and growing burden on healthcare systems. While individual studies have ...
Cost-Effectiveness Analysis of Etrasimod Compared With Biologic Therapies for the Treatment of Patients with Moderately-to-Severely Active Ulcerative Colitis in Spain
Cost-Effectiveness Analysis of Etrasimod Compared With Biologic Therapies for the Treatment of Patients with Moderately-to-Severely Active Ulcerative Colitis in Spain
Etrasimod (2 mg orally, once daily) is a novel advanced therapy (AT) for patients aged 16 years and older, with m...
Estimation of Health Utility Values for Eosinophilic Granulomatosis With Polyangiitis
Estimation of Health Utility Values for Eosinophilic Granulomatosis With Polyangiitis
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare autoimmune disease, characterised by inflammation of small-...
Model-Based Economic Analyses of Haemophilia from a Societal Perspective: A Scoping Review
Model-Based Economic Analyses of Haemophilia from a Societal Perspective: A Scoping Review
Haemophilia imposes substantial lifelong humanistic and economic burdens, necessitating economic evaluations that adopt a ...
Impact of Inhibitor Development on the Cost Effectiveness of Prophylactic Treatment with Recombinant Factor VIII in Previously Untreated Patients with Severe Hemophilia A
Impact of Inhibitor Development on the Cost Effectiveness of Prophylactic Treatment with Recombinant Factor VIII in Previously Untreated Patients with Severe Hemophilia A
Inhibitor development against recombinant factor VIII (rFVIII) is a significant complication in the prophylactic treatment...
Global Assessment of Health Utilities Associated with Pneumococcal Disease in Adults: Targeted Literature Reviews
Global Assessment of Health Utilities Associated with Pneumococcal Disease in Adults: Targeted Literature Reviews
Pneumococcal disease can significantly reduce quality of life (QoL). Health utilities are commonly used to assess QoL burd...
Societal Economic Burden of Antibiotic Resistance in Uganda: A Cost of Illness Study
Societal Economic Burden of Antibiotic Resistance in Uganda: A Cost of Illness Study
Antibiotic resistance (ABR), largely owing to inappropriate prescriptions and misuse of antibiotics, threatens the effecti...
Cost-Effectiveness of Chimeric Antigen Receptor (CAR) T-Cell Therapy for Blood Cancers: An Updated Systematic Review
Cost-Effectiveness of Chimeric Antigen Receptor (CAR) T-Cell Therapy for Blood Cancers: An Updated Systematic Review
Chimeric antigen receptor (CAR) T-cell therapy is an area of rapid development, showing the promise of curing blood cancer...
Use of Health State Utility Values in Cost-Utility Analyses of Selected Infectious Diseases in Aging Populations: A Systematic Review and Critical Appraisal
Use of Health State Utility Values in Cost-Utility Analyses of Selected Infectious Diseases in Aging Populations: A Systematic Review and Critical Appraisal
Health state utility values (HSUVs) are vital in cost-utility analyses (CUAs) that inform policymaking. However, suboptima...
Budget Impact of the LungFlag™ Predictive Risk Model for Lung Cancer Screening
Budget Impact of the LungFlag™ Predictive Risk Model for Lung Cancer Screening
Lung cancer screening has historically been associated with false-positive results that can lead to complications and incr...
Economic Evaluation of NHS England’s Type 2 Diabetes Path to Remission Pilot Scheme: Evidence From Real-World Data and Patient Simulation Modelling
Economic Evaluation of NHS England’s Type 2 Diabetes Path to Remission Pilot Scheme: Evidence From Real-World Data and Patient Simulation Modelling
The ‘Type 2 Diabetes Path to Remission’ programme (T2DPR) of NHS England (NHSE) is a low-calorie diet interven...
Potential Economic Value of Multi-cancer Early Detection Testing Under Differential Cost Trends for Cancer Screening and Management
Potential Economic Value of Multi-cancer Early Detection Testing Under Differential Cost Trends for Cancer Screening and Management
Multi-cancer early detection (MCED) tests aim to reduce the clinical and economic burden of cancer by detecting cases at e...
Retractions of Health Economic Evaluations: A Systematic Review
Retractions of Health Economic Evaluations: A Systematic Review
Retractions of scientific articles have increased over time, across different health fields, disease indications, and stud...
Semaglutide 2.4 mg versus Liraglutide 3 mg for the Treatment of Obesity in Greece: A Short-Term Cost-Effectiveness Analysis
Semaglutide 2.4 mg versus Liraglutide 3 mg for the Treatment of Obesity in Greece: A Short-Term Cost-Effectiveness Analysis
Obesity is a global health issue with significant economic implications for health systems. Pharmacotherapy, including sem...
Pricing for Multi-Indication Drugs in the Italian Regulatory Context
Pricing for Multi-Indication Drugs in the Italian Regulatory Context
The authorization of new therapeutic indications for drugs already reimbursed by the Italian National Health Service (NHS)...
From Vision to Reality: The EU’s Pharmaceutical Reforms and the Path to Improved Access
From Vision to Reality: The EU’s Pharmaceutical Reforms and the Path to Improved Access
Disparities in access to oncology medicines in European Union (EU) member states can impact patient outcomes profoundly, w...
Very Early Health Technology Assessment for Potential Predictive Biomarkers in the Treatment of Advanced Non-Small Cell Lung Cancer
Very Early Health Technology Assessment for Potential Predictive Biomarkers in the Treatment of Advanced Non-Small Cell Lung Cancer
Immune checkpoint inhibitor (ICI)-containing treatment is currently prescribed as first-line treatment for all patients wi...
Burden of Disease and Cost of Illness of Triple-Negative Breast Cancer in Portugal
Burden of Disease and Cost of Illness of Triple-Negative Breast Cancer in Portugal
Triple-negative breast cancer accounts for 15% of all breast cancer cases, and it has a lower survival rate and higher inc...
So Many Choices, So Little Value: Potential Savings from Selecting Cost-Effective Proton Pump Inhibitors
So Many Choices, So Little Value: Potential Savings from Selecting Cost-Effective Proton Pump Inhibitors
Given that Korea lacks measures to promote cost-effective prescribing, this study investigated the efficiency of prescribe...
Do We Understand Unmet Need? A Proposal to Use Length-Of-Life Equivalent (LOLE) as a Patient-Centric Measure of Unmet Need
Do We Understand Unmet Need? A Proposal to Use Length-Of-Life Equivalent (LOLE) as a Patient-Centric Measure of Unmet Need
Many decision-makers have emphasized the importance of leveraging patient experience data to measure unmet need. However, ...
Predicting Danish EQ-5D-5L Utilities Based on United Kingdom EQ-5D-3L Utilities for Use in Health Economic Models
Predicting Danish EQ-5D-5L Utilities Based on United Kingdom EQ-5D-3L Utilities for Use in Health Economic Models
Since 2021, the Danish Medicines Council recommends the use of the Danish EQ-5D-5L value set when estimating utilities. Th...
Costs and Complications of Respiratory Syncytial Virus and Acute Respiratory Infections in the Adult Population: Analysis of a German Claims Database
Costs and Complications of Respiratory Syncytial Virus and Acute Respiratory Infections in the Adult Population: Analysis of a German Claims Database
Respiratory syncytial virus (RSV) infections pose health and economic burdens to adults. Using claims data, we estimated R...
Cost-Effectiveness Analysis of Daridorexant for the Pharmacological Treatment of Chronic Insomnia Disorder in Adults
Cost-Effectiveness Analysis of Daridorexant for the Pharmacological Treatment of Chronic Insomnia Disorder in Adults
Daridorexant 50 mg is recommended for treating chronic insomnia in England, Wales (NICE, 2023) and Scotland (Scot...
Economic Burden of Acute Myeloid Leukemia in European Union: Results from a Systematic Review of Literature
Economic Burden of Acute Myeloid Leukemia in European Union: Results from a Systematic Review of Literature
Acute myeloid leukemia (AML) is a heterogenous malignancy whose management is associated with considerable healthcare reso...
Economic Evaluation of Patiromer in Patients with Concomitant Heart Failure and Chronic Kidney Disease in Italy
Economic Evaluation of Patiromer in Patients with Concomitant Heart Failure and Chronic Kidney Disease in Italy
Hyperkalaemia (HK), in patients with heart failure (HF) with and without chronic kidney disease (CKD), is potentially life...
Adjusting Health State Utility Values for Multiple Conditions: Real-World EQ-5D-3L Data Modeling in Brazil
Adjusting Health State Utility Values for Multiple Conditions: Real-World EQ-5D-3L Data Modeling in Brazil
Decision analytical models are typically included in health economic evaluations to represent clinical pathways and enable...
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