SCI Abstract

search
+
Targeted Metabolomics of Nucleotide Intermediates for Biomarker Discovery in Acute Kidney Injury
Acute kidney injury (AKI) is a common syndrome among critically ill patients with high incidence and high mortality, chara...
Establishment of the new dispersive solid phase microextraction method with green adsorbent CaAl-LDH hybrid with g-C 3 N 4 utilised for the determination of Pb 2+ in Instant cup noodles and environmental samples
Adsorbents with a significant adsorption capacity and high selectivity are required to identify and eliminate heavy metal ...
Construction and validation of a method for detecting DPP-IV activity and tissue distribution in C57 mice based on fluorescent probe
Dipeptidyl peptidase-IV (DPP-IV) is critical for drug metabolism and physiological regulation. In terms of species differe...
Analytical methods for glycoRNA detection: A systematic review
Glycosylated RNAs (glycoRNAs) are a groundbreaking discovery in glycobiology, extending the diversity of known glycoconjug...
Establishment and evaluation of the detection method for human adenovirus and its subtypes based on RAA-LFD technology
Abstract: In this research, we developed a rapid assay for detecting human adenovirus (HAdV) and its prevalent subtypes (i...
Ambient Ionization Mass Spectrometry for Rapid Screening of Illegal Adulteration in Traditional Chinese Medicines: A Review
Illegal adulteration of Traditional Chinese Medicines has become a critical global safety concern, driven by the covert ad...
Characterizing Noninvasively Conservation Status of Historical Wet Collections using Spatially Offset Raman Spectroscopy
Fluid-preserved specimens are central to the scientific and cultural value of natural history collections, yet their conse...
Correction: A portable fluorescent aptamer sensor for rapid quantitative detection of Hg2+
Correction for ‘A portable fluorescent aptamer sensor for rapid quantitative detection of Hg2+’ by Jiayi Li et al., Anal. ...
Untargeted UHPLC-Q-Orbitrap Metabolomics Reveals Hormonal Suppression and Candidate Serum Markers as Evidence of Testosterone Misuse in Cattle
The illicit use of androgenic anabolic steroids, such as 17β-testosterone, in food-producing animals poses significant ris...
A novel APE1-assisted cycling amplification for rapid and ultrasensitive SERS detection of TK1 mRNA in human serum
Quantitative mRNA expression levels are essential for differential and clinical diagnoses. In this work, we present an apu...
An Integrated Magnetic-Microfluidic Chemiluminescence Platform for Rapid Quantification of Exosomal miR-21 Associated with Breast Cancer
Accurate quantification of microRNAs (miRNAs) is crucial for early cancer diagnosis, but conventional techniques, such as ...
Hypoxia activated fluorescent probe for specific visualization of mitochondrial dysfunction in tumor
Selectively monitoring the mitochondrial dysfunction and viability of tumor was an important task for the treatment agains...
A novel electrochemical sensor for the analysis of vibegron as a newly approved FDA drug: A rational computational design and cleaning validation application
A novel analytical tool was developed for the assay of the recently approved β3-adrenergic receptor agonist “vibegron”. Th...
Selection of a DNA Aptamer for the Development of an Electrochemical Aptasensor for the Detection of Pb²⁺
In order to develop a simple, highly sensitive and cost-effective electrochemical sensor with high specificity for lead io...
Nanosensors as Diagnostic Tools: Emerging Concepts, Opportunities, and Design Barriers
Nanosensors have become a revolutionary tool, enabling early diagnosis and continuous monitoring of diseases with high acc...
Radical Reactivity of Aryl Thianthrenium Salts
Functionalization of the C(sp2)–H bond is a challenging yet highly useful synthetic task due to its relative inertness and...
I2/DMSO-Enabled Cascade Michael Addition/Oxidative Cyclization: Access to Imidazo[2,1-b][1,3,4]thiadiazoles
A straightforward protocol for accessing imidazo[2,1-b][1,3,4]thiadiazoles via I2-catalyzed tandem Michael addition-oxidat...
Theoretical Insights into the Cu-Catalyzed Boronation of Conjugated Trienes: Mechanism and Selectivity Control
The copper-catalyzed boronation of conjugated trienes offers a promising route to organoboron compounds but is often limit...
Tandem indium(III)-catalyzed cyclization and intermolecular hydrofunctionalization of 1,6-enynes
A tandem indium(III)-catalyzed cyclization and intermolecular hydrofunctionalization of 1,6-enynes for the stereoselective...
Preparation and Catalytic Properties of Benziodolium Salts
Dibenziodolium salts have recently emerged as useful iodine (III)-type halogen bonding (XB) donors. However, although benz...
Asymmetric Transfer Hydrogenation of Polyoxygenated 3-Arylidenechroman-4-ones: A Powerful Tool for the Total Synthesis of Natural Homoisoflavonoids
A mild and highly efficient one-pot asymmetric transfer hydrogenation (ATH) of challenging, electron-rich 3arylidenechroma...
Isoquinoline-Catalyzed Visible-Light-Mediated 1,2-/1,4-Thiosulfonylation Difunctionalization Reaction of Thiosulfates with Alkenes
We have developed a novel method for the 1,2-/1,4thiosulfonylation bifunctional reaction of thiosulfates with nonaromatic ...
Dehydrogenative Aromatization of Cyclohexanone Derivatives for the Synthesis of Site-selective Substituted Phenols and Anilines
Aromatic compounds containing phenol or aniline functionalities are ubiquitous building blocks in various fields both in a...
A Versatile and Practical One-Pot Strategy for a Greener, Waste-Minimized Synthesis of Aryloxy- and Alkyloxy-Substituted Metallophthalocyanines via Tandem SNAr-cyclotetramerization
Phthalocyanines represent molecules of considerable scientific interest, yet their synthesis remains challenging, particul...
Theoretical Insight: Dual Roles of Electron-Pair Donors and Acceptors in Activating and Mediating Iodine Atom Transfer
Lewis bases (Lbs) act as electron-pair donors and react with BH3 to form Lbs→BH3 complexes. In catalytic systems, these pr...
Visible light-driven construction of isoxazoline/isoxazole scaffolds via [2+2+1] cyclization of alkenes with tert-butyl nitrite
A visible light-driven [2+2+1] cyclization of alkenes with tert-butyl nitrite (TBN) has been developed for the efficient c...
Multi-site thiolation enables rapid and precise synthesis of 2-pyridone thioethers
The direct and selective functionalization of 2-pyridones remains a fundamental challenge in synthetic chemistry. While co...
Brønsted acid-catalyzed synthesis of trifluoromethylated azulenes via cyclization of 1-phenyl-2-CF3-1,3-enynes
Azulene and its derivatives are important scaffolds with broad applications. The introduction of a trifluoromethyl group i...
Photoredox Catalyzed Visible Light-Induced Reduction of Nitroarenes into Anilines
A photochemical methodology was developed for the reduction of nitroarenes, utilizing γ-terpinene as the reductant and 9-H...
Ligand-controlled Copper-catalyzed Carboamination Reactions of Styrenes and 1,3-Enynes to Access Diverse Imides
The multi-component reaction among alkenes, nitriles and carboxylic acids via the radical Ritter-type process is one of th...
Load More
format_indent_increase