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Gastro-stable liposomal Bee's propolis extract protects against cisplatin-induced hepato-renal toxicity in rats
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Edoxaban-loaded nanostructured GMS/sesame oil carriers for augmented antithrombotic activity
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Dual function composite hydrogel for rheumatoid arthritis management: Development and in-vivo evaluation in rat model
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Therapeutic potential of liquid crystal containing α-BISABOLOL in the treatment of diabetic wounds
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Harnessing liposome technology to deliver a Rubus ulmifolius fruit extract to hyperglycemic rats
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Ultrasound-controlled release of curcumin and nitric oxide for synergistic treatment of MRSA-infected pneumonia
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Cisplatin-BSA-based carbon dots for colorectal cancer detection and therapy
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Fabrication and in vivo evaluation of metformin hydrogel wound dressing in experimental rat model
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Intranasal delivery of nanocarriers for the treatment of schizophrenia: An overview of current research
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Effect of post-administration head movements on nasal irrigation and mesh nebuliser mediated sinus drug delivery
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Repurposing atorvastatin for uterine leiomyosarcoma: mevalonate pathway inhibition yields preclinical antitumor efficacy
Repurposing atorvastatin for uterine leiomyosarcoma: mevalonate pathway inhibition yields preclinical antitumor efficacy
Uterine leiomyosarcoma (ULMS) is a rare yet aggressive uterine malignancy with high recurrence and poor survival, promptin...
Epigenetic plasticity in cancer drug resistance: mechanistic insights and strategies for therapeutic intervention
Epigenetic plasticity in cancer drug resistance: mechanistic insights and strategies for therapeutic intervention
Therapy resistance remains a central barrier to durable clinical benefit across cancer types, limiting the long-term effic...
S1UTRSP5, a short restructured RNA from SLIT1 3′UTR, mitigates mouse cardiac remodeling via enhancing SlRT1 activity
S1UTRSP5, a short restructured RNA from SLIT1 3′UTR, mitigates mouse cardiac remodeling via enhancing SlRT1 activity
The 3′ untranslated regions (3′UTRs) have been known to regulate mRNA location, stability, and translation. 3&...
METTL3 loss exacerbates colitis via m6A-dependent Slc39a8 regulation and epithelial lineage depletion
METTL3 loss exacerbates colitis via m6A-dependent Slc39a8 regulation and epithelial lineage depletion
The intestinal epithelium maintains host-microbiota homeostasis, while inflammatory conditions, such as inflammatory bowel...
Serum/glucocorticoid-regulated kinase 1 regulates vascular inflammation in atherosclerosis
Serum/glucocorticoid-regulated kinase 1 regulates vascular inflammation in atherosclerosis
Endothelial and macrophage inflammation and sterol transport play an important role in atherogenesis. Serum/glucocorticoid...
Paclitaxel prodrug loaded high-density lipoprotein nanoparticles for chemoimmunotherapy of triple-negative breast cancer
Paclitaxel prodrug loaded high-density lipoprotein nanoparticles for chemoimmunotherapy of triple-negative breast cancer
Insufficient tumor-specific immunogenicity and cytotoxic T lymphocytes infiltration limit the therapeutic efficacy of comb...
Sevoflurane-induced disruption of critical period Arc signaling drives aberrant microglial synaptic pruning and cognitive deficits
Sevoflurane-induced disruption of critical period Arc signaling drives aberrant microglial synaptic pruning and cognitive deficits
Early-life sevoflurane exposure is associated with long-term cognitive deficits. Given that hippocampal development relies...
Amyloid-beta fibrils as active contributors to synaptic dysfunction in Alzheimer’s disease
Amyloid-beta fibrils as active contributors to synaptic dysfunction in Alzheimer’s disease
Alzheimer’s disease (AD) is a neurodegenerative disorder that is characterized by the accumulation of amyloid-beta (...
Advancing Vaccination Strategies for Older Adults: Insights of the Adult Immunization Board Meeting
Advancing Vaccination Strategies for Older Adults: Insights of the Adult Immunization Board Meeting
As Europe’s population ages, optimizing vaccination strategies for older adults is an increasing public health prior...
Association Between Anticholinergic Burden and Dry Mouth Severity in Acutely Ill Older Adults
Association Between Anticholinergic Burden and Dry Mouth Severity in Acutely Ill Older Adults
Dry mouth is a common and burdensome condition in older adults and its severity may increase with use of anticholinergic m...