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The role of subcortical brain tissue iron as an indicator of dopamine neurophysiology in adolescent cannabis use
The role of subcortical brain tissue iron as an indicator of dopamine neurophysiology in adolescent cannabis use
Approximately 10–20% of U.S. adolescents report past-year cannabis use (CU). Although regular CU beginning in adoles...
GABAergic neurons in the ventrolateral periaqueductal gray mediate fentanyl withdrawal and self-administration in mice
GABAergic neurons in the ventrolateral periaqueductal gray mediate fentanyl withdrawal and self-administration in mice
Opioid addiction is characterized by compulsive drug seeking and use, accompanied by pain and heightened pain sensitivity ...
Role of submedius thalamus and its interaction with orbitofrontal cortex in incubation of oxycodone craving
Role of submedius thalamus and its interaction with orbitofrontal cortex in incubation of oxycodone craving
A major obstacle in oxycodone addiction treatment is relapse during abstinence. In rats, oxycodone seeking intensifies dur...
White matter and impulsivity are prospectively associated with non‑suicidal self‑injury in youth: evidence for sex differences
White matter and impulsivity are prospectively associated with non‑suicidal self‑injury in youth: evidence for sex differences
Non-suicidal self-injury (NSSI) typically begins in adolescence and is associated with higher impulsivity and compromised ...
Cannabidiol corrects sleep deficits and reduces spontaneous seizures in Angelman syndrome model mice
Cannabidiol corrects sleep deficits and reduces spontaneous seizures in Angelman syndrome model mice
The off-label use of cannabidiol (CBD) has outpaced investigation. We assessed the effects of CBD in Angelman syndrome mod...
Effort, timing and choice: a refined rodent effort choice task with excellent sensitivity to dopamine modulators
Effort, timing and choice: a refined rodent effort choice task with excellent sensitivity to dopamine modulators
Motivational deficits and anhedonia are core features of psychiatric disorders such as depression, schizophrenia and addic...
Nucleus accumbens medial shell D1 and D2 medium spiny neurons signal the valence of conditioned stimuli in a sex-dependent manner
Nucleus accumbens medial shell D1 and D2 medium spiny neurons signal the valence of conditioned stimuli in a sex-dependent manner
Assigning valence to stimuli supports survival by promoting approach of stimuli associated with beneficial outcomes and av...
The prelimbic prefrontal cortex mediates the development of lasting social avoidance as a consequence of social threat conditioning
The prelimbic prefrontal cortex mediates the development of lasting social avoidance as a consequence of social threat conditioning
Social avoidance is highly detrimental for natural behavior. Despite much research on this topic, the mechanisms underlyin...
The crosstalk between CREB and PER2 mediates the transition between mania- and depression-like behavior
The crosstalk between CREB and PER2 mediates the transition between mania- and depression-like behavior
Bipolar disorder (BD) is a severe psychiatric disorder characterized by alternating manic and depressive episodes. The mol...
Connectome-based predictive modeling of early and chronic psychosis symptoms
Connectome-based predictive modeling of early and chronic psychosis symptoms
Previous research indicates that early (EP) and chronic (CP) psychosis share brain correlates and symptoms. However, notab...
A new module in the drug development process: preclinical multi-center randomized controlled trial of R-ketamine on alcohol relapse
A new module in the drug development process: preclinical multi-center randomized controlled trial of R-ketamine on alcohol relapse
The drug development process in psychiatry faces significant challenges due to low reproducibility rates in animal testing...
IN MEMORIAM: Floyd E. Bloom, M.D
IN MEMORIAM: Floyd E. Bloom, M.D
On January 8, 2025, the ACNP lost one of its guiding lights, Floyd E. Bloom,...
Persistent brain network signatures in psychosis: implications for diagnosis, prognosis, and treatment
This work was supported by the following sources: Northwell Health Advancing Women in Science and Medicine (Career Develop...
Greater subjective effects of a low dose of LSD in participants with depressed mood
Greater subjective effects of a low dose of LSD in participants with depressed mood
Recent studies and anecdotal reports suggest that psychedelics can improve mood states, even at low doses. However, few pl...
Correction: Voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes
Authors and AffiliationsDepartment of Neuroscience, University of Kentucky, Lexington, KY, USAMengfan Xia, Tanner L. Ander...
ACNP 62nd Annual Meeting: Poster Abstracts P1 – P250
Sanjay Mathew*, Andrew J. Cutler, Nicole C. Visitacion, Michael Gold, Jason Yuan, Bill AuroraBaylor College of Medicine, H...
ACNP 62nd Annual Meeting: Author Index
First Name Last Name Submission Number(s)Scott Aaronson P249, P323, P327Mahmood Y. Abdelkader P186She...
ACNP 62nd Annual Meeting: Poster Abstracts P251 – P500
Aki Tsuchiyagaito, Rayus Kuplicki, Ryan Smith, Masaya Misaki, Noah Philip, Martin Paulus, Salvador Guinjoan*Laureate Insti...
ACNP 62nd Annual Meeting: Keyword Index
Key Word Submission Number(s)(2R,6R)-hydroxynorketamine P354(R,S)-ketamine P250, P354, P365, P726(R,S...
ACNP 62nd Annual Meeting: Poster Abstracts P501 – P753
Johanna Seitz-Holland*, Cornelius Berberich, Nora Penzel, Kevin Cho Kang-Ik, Ofer Pasternak, Suheyla Cetin-Karayumak, Yoge...
ACNP 62nd Annual Meeting: Panels, Mini-Panels and Study Groups
Dong-Jing FuJanssen Research and Development, LLC, Titusville, New Jersey, United StatesBackground: Regulatory agency appr...
Inhibition of asparagine endopeptidase (AEP) effectively treats sporadic Alzheimer’s disease in mice
Inhibition of asparagine endopeptidase (AEP) effectively treats sporadic Alzheimer’s disease in mice
Alzheimer’s disease (AD) is a progressive neurodegenerative disease with cognitive dysfunction as its major clinical...
Correction: Neutralization of tumor necrosis factor-related apoptosis-inducing ligand reduces spinal cord injury damage in mice
Correction: Neutralization of tumor necrosis factor-related apoptosis-inducing ligand reduces spinal cord injury damage in mice
Authors and AffiliationsDepartment of Experimental and Clinical Pharmacology, University of Catania School of Medicine, Ca...
To lump or to split: cognitive impairment across mood and psychotic disorders
Wenzel J, Badde L, Haas SS, Bonivento C, Van Rheenen TE, Antonucci LA, et al. Transdiagnostic subgroups of cognitive impai...