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Targeting TRAP1-dependent metabolic reprogramming to overcome doxorubicin resistance in quiescent breast cancer
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CD105 blockade restores osimertinib sensitivity in drug-resistant EGFR-mutant non-small cell lung cancer
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Targeting cTRIP12 counteracts ferroptosis resistance and augments sensitivity to immunotherapy in pancreatic cancer
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MVP-LCN2 axis triggers evasion of ferroptosis to drive hepatocarcinogenesis and sorafenib resistance
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PARP inhibition elicits NK cell-associated immune evasion via potentiating HLA-G expression in tumor
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Aging and senescence: Key players in brain tumor progression and drug resistance
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Overcoming cancer therapy resistance: From drug innovation to therapeutics
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Novel insights into taxane pharmacology: An update on drug resistance mechanisms, immunomodulation and drug delivery strategies
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Methotrexate resistance and its regulatory mechanisms in pediatric tumors and beyond
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Role of the sulfur-containing amino acid-ROS axis in cancer chemotherapeutic drug resistance
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Lactylation in cancer progression and drug resistance
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Widespread antibiotic heterotolerance in bacteria remains undetected by resistance assays
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Upregulation of CoQ shifts ferroptosis dependence from GPX4 to FSP1 in acquired radioresistance
Upregulation of CoQ shifts ferroptosis dependence from GPX4 to FSP1 in acquired radioresistance
Acquired radioresistance is the primary cause of treatment failure in radiotherapy, which is considered as one of the prim...
Global Spread characteristics of CTX-M-type Extended-spectrum β-lactamases: a genomic epidemiology analysis
Global Spread characteristics of CTX-M-type Extended-spectrum β-lactamases: a genomic epidemiology analysis
The problem of bacterial resistance due to the massive and unregulated use of antibiotics is one of the most important pub...
Rewiring chaperone-mediated autophagy in cancer by a prion-like chemical inducer of proximity to counteract adaptive immune resistance
Rewiring chaperone-mediated autophagy in cancer by a prion-like chemical inducer of proximity to counteract adaptive immune resistance
Chaperone-mediated autophagy (CMA), a proteolytic system contributing to the degradation of intracellular proteins in lyso...
Vaccine effects on COVID-19 infection with bivalent boosting by age group
Vaccine effects on COVID-19 infection with bivalent boosting by age group
Available online 27 December 2023, 101039Author links open overlay panelABSTRACTThis paper examines time-series vaccine ef...
TRAIL-driven targeting and reversing cervical cancer radioresistance by seleno-nanotherapeutics through regulating cell metabolism
TRAIL-driven targeting and reversing cervical cancer radioresistance by seleno-nanotherapeutics through regulating cell metabolism
Globally, cervical cancer is a major health concern for women, with about 604,000 new cases and 342,000 deaths estimated i...
Cefiderocol: Clinical application and emergence of resistance
Cefiderocol: Clinical application and emergence of resistance
Antibiotic resistance has significantly impacted humankind, primarily due to the prolonged misuse of antibacterial drugs (...
Deciphering the genetic basis of resistome and virulome diversity among multidrug-resistant Mycoplasma hominis
Deciphering the genetic basis of resistome and virulome diversity among multidrug-resistant Mycoplasma hominis
Mycoplasma hominis is one of the smallest pathogens responsible for a diverse range of infections, including non-gonococca...
Progress in characterizing ABC multidrug transporters in zebrafish
Progress in characterizing ABC multidrug transporters in zebrafish
The ATP-binding cassette (ABC) transporter gene superfamily encodes membrane proteins that transport their substrates in a...
Global distribution and genomic characteristics of carbapenemase-producing Escherichia coli among humans, 2005-2023
Global distribution and genomic characteristics of carbapenemase-producing Escherichia coli among humans, 2005-2023
Antibiotic resistance represents a global public health crisis and poses a significant challenge worldwide (Laxminarayan e...