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Decoding Adipose Tissue Phenotypic Switching: From Mechanisms to Computational Drug Discovery
Decoding Adipose Tissue Phenotypic Switching: From Mechanisms to Computational Drug Discovery
This review aims to explore the therapeutic potential of brown adipose tissue (BAT) to combat obesity and associated metab...
Beyond the Scale: Setting Goals for Outcomes Beyond Weight in Evidence-based Obesity Treatment
Beyond the Scale: Setting Goals for Outcomes Beyond Weight in Evidence-based Obesity Treatment
As definitions of obesity evolve beyond a sole focus on weight, evidence-based obesity treatments may also benefit from a ...
Metabolic Flux Adaptations During GLP-1 Receptor Agonist Therapy: Redox Implications
Metabolic Flux Adaptations During GLP-1 Receptor Agonist Therapy: Redox Implications
GLP-1 receptor agonists (GLP-1RAs) have become central therapies for obesity and metabolic disease. Although these agents ...
Opportunities and Challenges for Precision Nutrition in Gestational Obesity Management
Opportunities and Challenges for Precision Nutrition in Gestational Obesity Management
This review summarizes current knowledge on precision nutrition in gestational obesity management and outlines priorities ...
Intelligence-driven Mechanomedicine for Weight Rebound in Obesity
Intelligence-driven Mechanomedicine for Weight Rebound in Obesity
This perspective aims to propose a mechanomedicine framework integrating the body’s intrinsic “mechanical inte...
Intersectionality in Weight Stigma Research: A Systematic Review of Empirical Evidence
Intersectionality in Weight Stigma Research: A Systematic Review of Empirical Evidence
Social stigma and discrimination based on body weight or size (weight stigma) contribute to inequities in healthcare acces...
Prioritising Indicators for Large-scale Monitoring and Assessment of Food Environments for Public Health
Prioritising Indicators for Large-scale Monitoring and Assessment of Food Environments for Public Health
This study aimed to prioritise key indicators for monitoring and assessing the healthiness of food environments, including...
The Epidemiology of the Global Syndemic in Africa: New Evidence and Key Insights
The Epidemiology of the Global Syndemic in Africa: New Evidence and Key Insights
Over the past decade, Sub-Saharan Africa has entered a new phase in the evolution of the global syndemic of undernutrition...
Autophagy in Obesity and Type 2 Diabetes: Beyond the Protective Paradigm
Autophagy in Obesity and Type 2 Diabetes: Beyond the Protective Paradigm
This review examines the current evidence on autophagy dysregulation in obesity and type 2 diabetes mellitus (T2DM), with ...
Burden of Intrapancreatic Fat Deposition in Type 2 Diabetes and the Role of Obesity: A Systematic Review and Meta-Analysis
Burden of Intrapancreatic Fat Deposition in Type 2 Diabetes and the Role of Obesity: A Systematic Review and Meta-Analysis
Growing evidence supports a role for high intrapancreatic fat deposition (IPFD) in the pathogenesis of type 2 dia...
How Have Researchers Estimated the Impact of Excess Weight on Mortality? A Systematic Review
How Have Researchers Estimated the Impact of Excess Weight on Mortality? A Systematic Review
The aim of this review is to describe and reflect on the methodology of the studies that estimate the attributable mortali...
The Role of Fathers in the Intergenerational Transmission of Obesity
The Role of Fathers in the Intergenerational Transmission of Obesity
This narrative review aims to synthesize recent evidence demonstrating that paternal influences can significantly affect c...
Synergistic Intervention for Obesity: Integrating Central Appetite Regulation and Peripheral Energy Expenditure
Synergistic Intervention for Obesity: Integrating Central Appetite Regulation and Peripheral Energy Expenditure
Obesity stems from a chronic imbalance between energy intake and expenditure. Current therapeutic strategies primarily foc...
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All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
From static lipids to dynamic risk: The role of atherogenic index of plasma in prediabetes
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Diabetes-driven oxidative stress and calcium dysregulation in gametogenesis and early fertilization
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Fixed-Dose Combination Therapy as a Strategy to Improve Antidiabetic Medication Adherence in People with Type 2 Diabetes: A Narrative Review
Fixed-Dose Combination Therapy as a Strategy to Improve Antidiabetic Medication Adherence in People with Type 2 Diabetes: A Narrative Review
Type 2 diabetes mellitus (T2DM) is a metabolic condition associated with increased morbidity, mortality and healthcare cos...
Optimizing Type 2 Diabetes Management in Iraq: Expert Consensus on Initiation and Intensification of Insulin-Based Treatment Options
Optimizing Type 2 Diabetes Management in Iraq: Expert Consensus on Initiation and Intensification of Insulin-Based Treatment Options
Type 2 diabetes mellitus (T2DM) prevalence in Iraq is projected to rise significantly by 2045, creating urgent need for op...
Impact of SGLT2 Inhibitors on Clinical Outcomes in Patients with Diabetes Mellitus Following Heart Transplantation: A Meta-analysis
Impact of SGLT2 Inhibitors on Clinical Outcomes in Patients with Diabetes Mellitus Following Heart Transplantation: A Meta-analysis
In this new era, heart transplantation (HT) is rapidly gaining popularity worldwide. Patients with end-stage heart disease...