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Vitamin D-Do Diet Recommendations for Health Remain Strong?
Vitamin D-Do Diet Recommendations for Health Remain Strong?
How will the scientific community and authoritative bodies define future nutritional requirements for vitamin D? At the In...
Between a Rock and a Short Place—The Impact of Nephrolithiasis on Skeletal Growth and Development Across the Lifespan
Between a Rock and a Short Place—The Impact of Nephrolithiasis on Skeletal Growth and Development Across the Lifespan
The impact of nephrolithiasis on skeletal growth and bone health across the life span of kidney stone formers is reviewed....
Adiposity and Mineral Balance in Chronic Kidney Disease
Adiposity and Mineral Balance in Chronic Kidney Disease
Bone homeostasis is balanced between formation and resorption activities and remain in relative equilibrium. Under disease...
Associations Among Estrogens, the Gut Microbiome and Osteoporosis
Associations Among Estrogens, the Gut Microbiome and Osteoporosis
The purpose of this Review was to summarize the evidence on the associations among estrogen status, cellular senescence, t...
Role of Chemokines and Cytokines in Prostate Cancer Skeletal Metastasis
Role of Chemokines and Cytokines in Prostate Cancer Skeletal Metastasis
Once prostate cancer (PCa) bone metastases develop, the prognosis dramatically declines. The precise mechanisms regulating...
Association Between Air Pollution and Osteoporosis with High-Risk Populations: A Narrative Review
Association Between Air Pollution and Osteoporosis with High-Risk Populations: A Narrative Review
Air pollution has been raised as a novel risk factor for osteoporosis, which impose a huge burden on both individuals and ...
DAMPs, PAMPs, NLRs, RIGs, CLRs and TLRs – Understanding the Alphabet Soup in the Context of Bone Biology
DAMPs, PAMPs, NLRs, RIGs, CLRs and TLRs – Understanding the Alphabet Soup in the Context of Bone Biology
The purpose of this review is to summarize the current understanding of cell-autonomous innate immune pathways that contri...
Calcium Supplementation- Efficacy and Safety
Calcium Supplementation- Efficacy and Safety
To assess the efficacy of calcium supplements in preventing fractures, and to review their adverse effects, particularly o...
Management of Bone Health in Adult Mastocytosis
Management of Bone Health in Adult Mastocytosis
The present review will examine bone disease in mastocytosis, analyze the existing literature on its management, and propo...
Management of Adverse Skeletal Effects Following Bariatric Surgery Procedures in People Living with Obesity
Management of Adverse Skeletal Effects Following Bariatric Surgery Procedures in People Living with Obesity
This review focuses on recent findi+ngs regarding the management of adverse skeletal effects following weight loss in peop...
Congenital Bone Disorders Associated with ERI1-Mediated RNA Metabolism Dysfunction: Spondylo-Epi-Metaphyseal Dysplasia Guo-Campeau Type and Beyond
Congenital Bone Disorders Associated with ERI1-Mediated RNA Metabolism Dysfunction: Spondylo-Epi-Metaphyseal Dysplasia Guo-Campeau Type and Beyond
The purpose of this review is to explore the multifaceted roles of the ERI1 exoribonuclease, particularly in RNA metabolis...
PTH Substitution Therapy for Chronic Hypoparathyroidism: PTH 1–84 and Palopegteriparatide
PTH Substitution Therapy for Chronic Hypoparathyroidism: PTH 1–84 and Palopegteriparatide
to describe and compare the efficacy and safety of the main PTH treatments, namely PTH(1–84) and palopegteriparatide...
Medical Management of Hypophosphatasia: Review of Data on Asfotase Alfa
Medical Management of Hypophosphatasia: Review of Data on Asfotase Alfa
Hypophosphatasia (HPP) is a rare, dento-osseous disorder caused by impaired activity of tissue non-specific alkaline phosp...
Chronic Kidney Disease-Mineral and Bone Disorder Management in 4D: The Case for Dynamic Treatment Regime Methods to Optimize Care
Chronic Kidney Disease-Mineral and Bone Disorder Management in 4D: The Case for Dynamic Treatment Regime Methods to Optimize Care
Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) is a complex condition impacting patients with kidney failure a...
Practical Compass of Single-Cell RNA-Seq Analysis
Practical Compass of Single-Cell RNA-Seq Analysis
This review paper provides step-by-step instructions on the fundamental process, from handling fastq datasets to illustrat...
Racial/Ethnic Differences in Bone Mineral Density for Osteoporosis
Racial/Ethnic Differences in Bone Mineral Density for Osteoporosis
We primarily aim to review differences in bone mineral density (BMD) for osteoporosis among different racial/ethnic groups...
Loss of Muscle Mass and Strength After Hip Fracture: an Intervention Target for Nutrition Supplementation
Loss of Muscle Mass and Strength After Hip Fracture: an Intervention Target for Nutrition Supplementation
To summarize what is known about the deleterious effect of hip fracture on muscle mass and strength as well as the scienti...
Biomimetic Inspired Hydrogels for Regenerative Vertebral Body Stenting
Biomimetic Inspired Hydrogels for Regenerative Vertebral Body Stenting
This review aims to explore the potential of biomimetic hydrogels as an alternative to bone cement in vertebral body stent...
Zebrafish as a Model for Osteoporosis: Functional Validations of Genome-Wide Association Studies
Zebrafish as a Model for Osteoporosis: Functional Validations of Genome-Wide Association Studies
GWAS, as a largely correlational analysis, requires in vitro or in vivo validation. Zebrafish (Danio rerio) have many adva...
Weight-bearing Guidelines for Common Geriatric Upper and Lower Extremity Fractures
Weight-bearing Guidelines for Common Geriatric Upper and Lower Extremity Fractures
The purpose of this review paper is to summarize current weight-bearing guidelines for common geriatric fractures, around ...
Characterizing Bone Phenotypes Related to Skeletal Fragility Using Advanced Medical Imaging
Characterizing Bone Phenotypes Related to Skeletal Fragility Using Advanced Medical Imaging
Summarize the recent literature that investigates how advanced medical imaging has contributed to our understanding of ske...
Bone Material Properties in Bone Diseases Affecting Children
Bone Material Properties in Bone Diseases Affecting Children
Metabolic and genetic bone disorders affect not only bone mass but often also the bone material, including degree of miner...
Micropetrosis: Osteocyte Lacunar Mineralization in Aging and Disease
Micropetrosis: Osteocyte Lacunar Mineralization in Aging and Disease
As the importance of osteocytes for bone mineral homeostasis is increasingly recognized, there is growing interest in oste...
Correction: Bringing Mechanical Context to Image-Based Measurements of Bone Integrity
Correction: Bringing Mechanical Context to Image-Based Measurements of Bone Integrity
Department of Anatomy, Physiology and Pharmacology, University of Saskatchewan, 105 Administration Place, Saskatoon, SK, S...
The Origin and Fate of Chondrocytes: Cell Plasticity in Physiological Setting
The Origin and Fate of Chondrocytes: Cell Plasticity in Physiological Setting
Here, we discuss the origin of chondrocytes, their destiny, and their plasticity in relationship to bone growth, articulat...
The Differential Effect of Metformin on Osteocytes, Osteoblasts, and Osteoclasts
The Differential Effect of Metformin on Osteocytes, Osteoblasts, and Osteoclasts
Metformin is an anti-glycemic agent, which is widely prescribed to diabetes patients. Although its alleged role on bone st...
Genetic and Gene Expression Resources for Osteoporosis and Bone Biology Research
Genetic and Gene Expression Resources for Osteoporosis and Bone Biology Research
The integration of data from multiple genomic assays from humans and non-human model organisms is an effective approach to...
Novel Insights into Osteoclast Energy Metabolism
Novel Insights into Osteoclast Energy Metabolism
Osteoclasts are crucial for the dynamic remodeling of bone as they resorb old and damaged bone, making space for new bone....
Inflammatory Processes Affecting Bone Health and Repair
Inflammatory Processes Affecting Bone Health and Repair
The purpose of this article is to review the current understanding of inflammatory processes on bone, including direct imp...
Osteocyte Mechanotransduction in Orthodontic Tooth Movement
Osteocyte Mechanotransduction in Orthodontic Tooth Movement
Orthodontic tooth movement is characterized by periodontal tissue responses to mechanical loading, leading to clinically r...
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