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Dissecting the genetic determinants and biological associations between body mass index and female reproductive disorders based on genome-wide association study
Dissecting the genetic determinants and biological associations between body mass index and female reproductive disorders based on genome-wide association study
While the phenotypic link between body mass index (BMI) and some female reproductive disorders is well established, the ge...
The aryl hydrocarbon receptor: a new frontier in male reproductive system
The aryl hydrocarbon receptor: a new frontier in male reproductive system
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor historically recognized for its role in the...
Phosphate concentrations in follicular fluid during assisted reproductive treatment: relevance for ovarian function and fertility outcomes
Phosphate concentrations in follicular fluid during assisted reproductive treatment: relevance for ovarian function and fertility outcomes
The role of follicular fluid phosphate for reproductive health and oocyte maturation is unclear. This study investigates t...
GnRH-a use before programmed frozen embryo transfer cycles for women with PCOS: a retrospective cohort study
GnRH-a use before programmed frozen embryo transfer cycles for women with PCOS: a retrospective cohort study
Programmed protocols are most commonly chosen as endometrial preparation for women with polycystic ovarian syndrome (PCOS)...
Euploidy rate and pregnancy outcomes in preimplantation genetic testing for aneuploidy cycles using progestin-primed ovarian stimulation versus GnRH antagonist protocol
Euploidy rate and pregnancy outcomes in preimplantation genetic testing for aneuploidy cycles using progestin-primed ovarian stimulation versus GnRH antagonist protocol
Previous studies has yielded contradictory findings regarding the relationship between controlled ovarian hyperstimulation...
Follitropin delta combined with menotropin in patients at risk for poor ovarian response during in vitro fertilization cycles: a prospective controlled clinical study
Follitropin delta combined with menotropin in patients at risk for poor ovarian response during in vitro fertilization cycles: a prospective controlled clinical study
The maximum daily dose of follitropin delta for ovarian stimulation in the first in vitro fertilization cycle is 12 ...
The association between serum testosterone level and congestive heart failure in US male adults: data from National Health and Nutrition Examination Survey (NHANES) 2011–2016
The association between serum testosterone level and congestive heart failure in US male adults: data from National Health and Nutrition Examination Survey (NHANES) 2011–2016
This study aimed to investigate the relationship between serum testosterone levels and the risk of congestive heart failur...
The impact of COVID-19 on the mental and sexual health of patients with infertility: a prospective before-and-after study
The impact of COVID-19 on the mental and sexual health of patients with infertility: a prospective before-and-after study
The coronavirus disease (COVID-19) pandemic has seriously impacted the mental and sexual health of the general population....
Outcomes of BRCA pre-implantation genetic testing according to the parental mutation origin: a cohort study
Outcomes of BRCA pre-implantation genetic testing according to the parental mutation origin: a cohort study
The process of gamete formation and early embryonic development involves rapid DNA replication, chromosome segregation and...
Diagnosis and management of infertility: NICE-adapted guidelines from the Italian Society of Human Reproduction
Diagnosis and management of infertility: NICE-adapted guidelines from the Italian Society of Human Reproduction
In Italy the fertility rate is very low, and an increasing number of patients are infertile and require treatments. The It...
Correlation between controlled ovarian stimulation protocols and euploid blastocyst rate in pre-implantation genetic testing for aneuploidy cycles
Correlation between controlled ovarian stimulation protocols and euploid blastocyst rate in pre-implantation genetic testing for aneuploidy cycles
Several studies have explored which COS protocol yields a higher blastocyst euploidy rate, but findings have been inconsis...
hMG addition affects the change in progesterone level during IVF stimulation and LBR: a retrospective cohort study
hMG addition affects the change in progesterone level during IVF stimulation and LBR: a retrospective cohort study
Premature progesterone (P) rise during IVF stimulation reduces endometrial receptivity and is associated with lower pregna...
Y chromosome microdeletions in Chinese men with infertility: prevalence, phenotypes, and intracytoplasmic sperm injection outcomes
Y chromosome microdeletions in Chinese men with infertility: prevalence, phenotypes, and intracytoplasmic sperm injection outcomes
The incidence of Y chromosome microdeletions varies among men with infertility across regions and ethnicities worldwide. H...
25(OH)D3 improves granulosa cell proliferation and IVF pregnancy outcomes in patients with endometriosis by increasing G2M+S phase cells
25(OH)D3 improves granulosa cell proliferation and IVF pregnancy outcomes in patients with endometriosis by increasing G2M+S phase cells
The 25-hydroxyvitamin D3 (25 (OH) D3) is crucial for follicular development. This study aimed to investigate the relations...
Nuclear-cytoplasmic asynchrony in oocyte maturation caused by TUBB8 variants via impairing microtubule function: a novel pathogenic mechanism
Nuclear-cytoplasmic asynchrony in oocyte maturation caused by TUBB8 variants via impairing microtubule function: a novel pathogenic mechanism
TUBB8, a crucial gene encoding microtubule protein, plays a pivotal role in cellular processes. Deleterious TUBB8 variants...
A review of nitric oxide and oxidative stress in typical ovulatory women and in the pathogenesis of ovulatory dysfunction in PCOS
A review of nitric oxide and oxidative stress in typical ovulatory women and in the pathogenesis of ovulatory dysfunction in PCOS
Polycystic ovary syndrome (PCOS) is a heterogeneous functional endocrine disorder associated with a low-grade, chronic inf...
Pregnancy prediction via ultrasound-detected endometrial blood for hormone replacement therapy-frozen embryo transfer: a prospective observational study
Pregnancy prediction via ultrasound-detected endometrial blood for hormone replacement therapy-frozen embryo transfer: a prospective observational study
This study aimed to assess the predictive value of endometrial blood flow branches on pregnancy outcomes after hormone rep...
Multi-omics study identifies that PICK1 deficiency causes male infertility by inhibiting vesicle trafficking in Sertoli cells
Multi-omics study identifies that PICK1 deficiency causes male infertility by inhibiting vesicle trafficking in Sertoli cells
Infertility affects approximately 10–15% of reproductive-age men worldwide, and genetic causes play a role in one-th...
Association of insulin resistance with polycystic ovary syndrome phenotypes and patients’ characteristics: a cross-sectional study in Iran
Association of insulin resistance with polycystic ovary syndrome phenotypes and patients’ characteristics: a cross-sectional study in Iran
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women. This disorder affects 6–15% of wome...
Thyroid hormone transport and metabolism are disturbed in the placental villi of miscarriage
Thyroid hormone transport and metabolism are disturbed in the placental villi of miscarriage
It has been long known that thyroid hormone regulates placental villi development, which is associated with the occurrence...
Body mass index impacts ectopic pregnancy during in vitro fertilization: an analysis of 42,362 clinical pregnancy cycles
Body mass index impacts ectopic pregnancy during in vitro fertilization: an analysis of 42,362 clinical pregnancy cycles
This large, single-center, retrospective cohort study was aimed to explore the effect of female body mass index (BMI) on e...
Correction: Mifepristone inhibited the expression of B7-H2, B7-H3, B7-H4 and PD-L2 in adenomyosis
Correction: Mifepristone inhibited the expression of B7-H2, B7-H3, B7-H4 and PD-L2 in adenomyosis
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Decreased HAT1 expression in granulosa cells disturbs oocyte meiosis during mouse ovarian aging
Decreased HAT1 expression in granulosa cells disturbs oocyte meiosis during mouse ovarian aging
With advanced maternal age, abnormalities during oocyte meiosis increase significantly. Aneuploidy is an important reason ...
Small RNAs, spermatogenesis, and male infertility: a decade of retrospect
Small RNAs, spermatogenesis, and male infertility: a decade of retrospect
Small non-coding RNAs (sncRNAs), being the top regulators of gene expression, have been thoroughly studied in various biol...
Endometriosis and IVF treatment outcomes: unpacking the process
Endometriosis and IVF treatment outcomes: unpacking the process
Advanced endometriosis is associated with a reduction of IVF success. Surgical damage to the ovarian reserve following the...
Application of elastography to diagnose adenomyosis and evaluate the degree of dysmenorrhea: a prospective observational study
Application of elastography to diagnose adenomyosis and evaluate the degree of dysmenorrhea: a prospective observational study
To determine whether there is a correlation between stiffness measured by strain elastography and the severity of dysmenor...
Longitudinal changes of oxidative stress and PON1 lactonase activity and status in older pregnant women undergoing assisted reproductive technology: a prospective nested case-control study
Longitudinal changes of oxidative stress and PON1 lactonase activity and status in older pregnant women undergoing assisted reproductive technology: a prospective nested case-control study
Childbearing in women with advanced maternal age (AMA) has increased the need for artificial reproductive technology (ART)...
Applications of laser technology in the manipulation of human spermatozoa
Applications of laser technology in the manipulation of human spermatozoa
The application of laser technology in the field of assisted reproductive technology (ART) has experienced rapid growth ov...
Circulating acyl-CoA-binding protein/diazepam-binding inhibitor in gestational diabetes mellitus
Circulating acyl-CoA-binding protein/diazepam-binding inhibitor in gestational diabetes mellitus
Acyl-CoA-binding protein (ACBP)/diazepam-binding inhibitor has recently been characterized as an endocrine factor affectin...
Cumulative live birth rates with autologous oocytes plateau with fewer number of cycles for each year of age > 42
Cumulative live birth rates with autologous oocytes plateau with fewer number of cycles for each year of age > 42
To disaggregate the Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) age category ...
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