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Reviews in endocrine and metabolic disorders
Reviews in endocrine and metabolic disorders
This is the first 2026 volume of Reviews in Endocrine and Metabolic Disorders (REMD)....
The evolving concept from Cardiovascular-kidney-metabolic syndrome to metabolic associated liver-cardiovascular-kidney syndrome: insights from endocrinology
The evolving concept from Cardiovascular-kidney-metabolic syndrome to metabolic associated liver-cardiovascular-kidney syndrome: insights from endocrinology
Metabolic diseases, cardiovascular diseases (CVD), and chronic kidney disease (CKD) often coexist. To understand the compl...
Hypothalamic control of arousal
Hypothalamic control of arousal
The hypothalamus is a federation of nuclei with a broad range of homeostatic functions, including regulation of sleep and ...
Disease activity and maternal–fetal outcomes in pregnant women with cushing’s syndrome: a systematic review and meta‑analysis
Disease activity and maternal–fetal outcomes in pregnant women with cushing’s syndrome: a systematic review and meta‑analysis
Pregnancy in women with Cushing’s syndrome (CS) is uncommon due to the detrimental effects of hypercortisolism on fe...
The role of monoclonal antibodies against IL-6 or IL-6R in the treatment of thyroid eye disease
The role of monoclonal antibodies against IL-6 or IL-6R in the treatment of thyroid eye disease
Thyroid eye disease (TED) is a chronic inflammatory autoimmune disorder characterized by expansion and fibrosis of orbital...
Live tissue microbiota and bacterial translocation: mechanisms and translational perspectives in cardiometabolic diseases
Live tissue microbiota and bacterial translocation: mechanisms and translational perspectives in cardiometabolic diseases
The long-standing view of sterile internal tissues has been challenged by accumulating evidence that microbial material, a...
Use of osilodrostat in a block-and-replace and titration strategy for cushing’s syndrome: a position paper by French experts
Use of osilodrostat in a block-and-replace and titration strategy for cushing’s syndrome: a position paper by French experts
The primary treatment for active Cushing’s Syndrome (CS) is the surgical removal of the causative tumor. Alternative...
Efficacy of different types of intermittent fasting in improving glycemic control in adults with overweight or obesity: a systematic review and network meta-analysis
Efficacy of different types of intermittent fasting in improving glycemic control in adults with overweight or obesity: a systematic review and network meta-analysis
Intermittent fasting (IF) aids the management of obesity and impaired glucose homeostasis, although the comparative effica...
Hypothalamic wars: the last nanodelivery
Hypothalamic wars: the last nanodelivery
The hypothalamus plays important roles in maintaining overall body homeostasis and energy balance. Disruption of its norma...
Obestatin: canonical and unexpected functions
Obestatin: canonical and unexpected functions
The functions of appetite-regulating hormones have been studied for decades with the aim of finding a solution to the prob...
The longitudinal impact of individual and parental emotional factors and individual behavioral factors on weight and disordered eating: A scoping review
The longitudinal impact of individual and parental emotional factors and individual behavioral factors on weight and disordered eating: A scoping review
Emotional and behavioral problems during childhood and adolescence play a significant role in the development of disordere...
A 50 year review of hyperpalatable foods consumed in binge-eating episodes
A 50 year review of hyperpalatable foods consumed in binge-eating episodes
Hyperpalatable foods containing hedonically reinforcing combinations of fat, sugar, carbohydrates, and sodium have increas...
Early-life programming of hypothalamic circuits by maternal obesity: implications for neuroendocrine disorders
Early-life programming of hypothalamic circuits by maternal obesity: implications for neuroendocrine disorders
Obesity in women before or during conception can exert lasting effects on offspring metabolic and neuroendocrine health. E...
The 24/7 lifestyle and male hormonal health: how sleep deprivation and ultra-processed foods impact testosterone and reproduction
The 24/7 lifestyle and male hormonal health: how sleep deprivation and ultra-processed foods impact testosterone and reproduction
Sleep is a fundamental physiological state essential for the regulation of multiple biological systems, including hormonal...
Neurocognitive performance and appetite-regulating hormones in obesity with and without eating disorders: A comprehensive review and empirical analysis
Neurocognitive performance and appetite-regulating hormones in obesity with and without eating disorders: A comprehensive review and empirical analysis
Obesity and eating disorders (ED) share neurocognitive vulnerabilities involving executive control and reward processing, ...
Algorithm-guided insulin therapy in hospitalized patients: current evidence, implementation challenges, and future perspectives
Algorithm-guided insulin therapy in hospitalized patients: current evidence, implementation challenges, and future perspectives
Up to 40% of hospitalized patients experience hyperglycemia, often caused by undiagnosed diabetes or stress-induced hyperg...
Hypothalamus-liver talks: whispers in the language of metabolism
Hypothalamus-liver talks: whispers in the language of metabolism
Closely associated with the exponential increase of obesity and sedentary life, liver-related disorders are a major global...
Targeting the activin/myostatin - actrii pathway to preserve skeletal muscle mass in obesity: mechanistic insights and therapeutic perspectives
Targeting the activin/myostatin - actrii pathway to preserve skeletal muscle mass in obesity: mechanistic insights and therapeutic perspectives
Skeletal muscle deterioration is a relevant complication of obesity associated with poor physical function, impairment of ...
Pregnancy-associated thyroid disorders: the role of genetic, epigenetic, and oxidative stress factors
Pregnancy-associated thyroid disorders: the role of genetic, epigenetic, and oxidative stress factors
Thyroid inflammation during pregnancy, particularly Hashimoto’s thyroiditis (HT) and postpartum thyroiditis (PPT), h...
Mechanisms of exercise in preventing cardiovascular diseases: Insights from gut microbiota characteristics in pathological states of cardiovascular diseases
Mechanisms of exercise in preventing cardiovascular diseases: Insights from gut microbiota characteristics in pathological states of cardiovascular diseases
Cardiovascular diseases (CVD) are major lethal diseases worldwide. Imbalance of gut microbiota (GM) homeostasis affects th...
Pathophysiological insights into asprosin: an emerging adipokine in reproductive health
Pathophysiological insights into asprosin: an emerging adipokine in reproductive health
Asprosin is a versatile protein hormone primarily produced by white adipose tissue (WAT). When secreted into the bloodstre...
Lights or shadows, a promising future for positron emission tomography in pituitary tumors: a systematic review
Lights or shadows, a promising future for positron emission tomography in pituitary tumors: a systematic review
The diagnosis of pituitary adenomas (PAs), also called pituitary tumors or neuroendocrine tumors (PitNETs) currently invol...
Exploring obesity phenotypes: a longitudinal perspective
Exploring obesity phenotypes: a longitudinal perspective
Traditional reliance on Body Mass Index (BMI) as a diagnostic tool for obesity is increasingly challenged due to its inabi...
Association between continuous glucose monitoring metrics and cardiovascular autonomic neuropathy in diabetic patients: a systematic review
Association between continuous glucose monitoring metrics and cardiovascular autonomic neuropathy in diabetic patients: a systematic review
Cardiovascular autonomic neuropathy (CAN) is a serious and prevalent complication of diabetes, linked to significant morbi...
Neurovascular plasticity as a modulator of hypothalamic function
Neurovascular plasticity as a modulator of hypothalamic function
The hypothalamus, located at the most ventral part of the brain, is the central regulator of homeostatic processes such as...
Sexual dimorphism in the development and function of the melanocortin system
Sexual dimorphism in the development and function of the melanocortin system
The melanocortin system is fundamental for the regulation of whole-body energy homeostasis. This system consists of pro-op...
Targeted therapeutic strategies as alternative and sustainable treatment options for obesity-induced steatohepatitis
Targeted therapeutic strategies as alternative and sustainable treatment options for obesity-induced steatohepatitis
The development of metabolic dysfunction-associated steatotic liver disease (MASLD), and its progression to metabolic dysf...
Hyperphagia in rare melanocortin-4 receptor pathway diseases: therapeutic options and assessing treatment response
Hyperphagia in rare melanocortin-4 receptor pathway diseases: therapeutic options and assessing treatment response
Hyperphagia is a hallmark of both congenital and acquired rare melanocortin-4 receptor (MC4R) pathway diseases. Currently,...
BBSome: An essential component of hypothalamic regulation of energy homeostasis
BBSome: An essential component of hypothalamic regulation of energy homeostasis
The BBSome is a protein complex composed of eight Bardet-Biedl syndrome (BBS) proteins. Although the BBSome is best known ...
Body mass index and body composition changes in transgender people undergoing gender-affirming hormone therapy: a systematic review and meta-analysis
Body mass index and body composition changes in transgender people undergoing gender-affirming hormone therapy: a systematic review and meta-analysis
Gender-affirming hormone therapy (GAHT) uses sex steroid hormones to induce desired physical changes, improving the qualit...
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