Rubino F, Cummings DE, Eckel RH, Cohen RV, Wilding JPH, Brown WA et al. Definition and diagnostic criteria of clinical obesity. Lancet Diabetes Endocrinol [Internet]. 2025; Available from: http://www.ncbi.nlm.nih.gov/pubmed/39824205

Bosy-Westphal A, Müller MJ. Diagnosis of obesity based on body composition-associated health risks—Time for a change in paradigm. Obes Rev. 2021;22:S2.

Article  Google Scholar 

Costa-Urrutia P, Vizuet-Gámez A, Ramirez-Alcántara M, Guillen-González MÁ, Medina-Contreras O, Valdes-Moreno M, et al. Obesity measured as percent body fat, relationship with body mass index, and percentile curves for Mexican pediatric population. PLoS ONE. 2019;14(2):1–13.

Article  Google Scholar 

Deurenberg P, Yap M, van Staveren W. Body mass index and percent body fat: a meta analysis among different ethnic groups. Int J Obes. 1998;22(12):1164–71.

Article  CAS  Google Scholar 

The Association of Life Insurance Medical Directors and the Actuarial Society of America. Medico-actuarial mortality investigation. The Association of Life Insurance Medical Directors and the Actuarial Society of America. 1913. Obes Res. 1995;3(1):100–6.

Billewicz WZ, Kemsley WFF, Thomson AM. INDICES OF ADIPOSITY. 16, Brit J Prev Soc Med. 1962.

Falk IS, Louis I, Dublin. November 1, 1882-March 7, 1969. Am J Public Health Nations Health [Internet]. 1969;59(7):1083–5. Available from: https://ajph.aphapublications.org/doi/full/https://doi.org/10.2105/AJPH.59.7.1083

Kelly TL, Wilson KE, Heymsfield SB. Dual energy X-ray absorptiometry body composition reference values from NHANES. PLoS ONE. 2009;4(9).

Pray R, Riskin S. The History and Faults of the Body Mass Index and Where to Look Next: A Literature Review. Cureus. 2023.

Keys A, Fidanza F, Karvonen,$ MJ, Kimura N, Taylor ~ HL. INDICES OF RELATIVE WEIGHT AND OBESITY. J Chron Dis. Volume 25. Pergamon; 1972.

Gutin I. In BMI we trust: reframing the body mass index as a measure of health. Social Theory Health. 2018;16(3):256–71.

Article  PubMed  Google Scholar 

Norman K, Stobäus N, Pirlich M, Bosy-Westphal A. Bioelectrical phase angle and impedance vector analysis - Clinical relevance and applicability of impedance parameters. Clin Nutr. 2012;31:854–61.

Article  PubMed  Google Scholar 

Stefan N, Häring HU, Hu FB, Schulze MB. Metabolically healthy obesity: Epidemiology, mechanisms, and clinical implications. Vol. 1, The Lancet Diabetes and Endocrinology. 2013. pp. 152–62.

Jung CH, Lee WJ, Song KH. Metabolically healthy obesity: A friend or foe? Korean Journal of Internal Medicine. Volume 32. Korean Association of Internal Medicine; 2017. pp. 611–21.

Prado CM, Cristina Gonzalez M, Heymsfield SB. Body composition phenotypes and obesity paradox. Vol. 18, Current Opinion in Clinical Nutrition and Metabolic Care. Lippincott Williams and Wilkins; 2015. pp. 535–51.

Carbone S, Canada JM, Billingsley HE, Siddiqui MS, Elagizi A, Lavie CJ. Obesity paradox in cardiovascular disease: where do we stand? Vascular Health and Risk Management. Volume 15. Dove Medical Press Ltd.; 2019. pp. 89–100.

Prado CMM, Siervo M, Mire E, Heymsfield SB, Stephan BCM, Broyles S, et al. A population-based approach to define body-composition phenotypes. Am J Clin Nutr. 2014;99(6):1369–77.

Article  CAS  PubMed  Google Scholar 

BAUMGARTNER RN. Body Composition in Healthy Aging, Ann NY, Acad Sci. [Internet]. 2000;904(1):437–48. Available from: https://nyaspubs.onlinelibrary.wiley.com/doi/https://doi.org/10.1111/j.1749-6632.2000.tb06498.x

April-Sanders AK, Rodriguez CJ. Metabolically healthy obesity redefined. JAMA Network Open. Volume 4. American Medical Association; 2021.

Duque AP, Luiz F, Rodrigues J, Mediano MFF, Tibiriça E, De Lorenzo A. Emerging concepts in metabolically healthy obesity [Internet]. Vol. 10, Am J Cardiovasc Dis. 2020. Available from: www.AJCD.us/.

Blüher M. Metabolically healthy obesity. Vol. 41, endocrine reviews. Endocrine Society; 2020. pp. 405–20.

Stefan N. Metabolically healthy and unhealthy normal weight and obesity. Endocrinol Metabolism. 2020;35(3):487–93.

Article  CAS  Google Scholar 

Liu C, Wang C, Guan S, Liu H, Wu X, Zhang Z, et al. The prevalence of metabolically healthy and unhealthy obesity according to different criteria. Obes Facts. 2019;12(1):78–90.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cypess AM. Reassessing human adipose tissue. N Engl J Med. 2022;386(8):768–79.

Article  CAS  PubMed  Google Scholar 

Clemente-Suárez VJ, Redondo-Flórez L, Beltrán-Velasco AI, Martín-Rodríguez A, Martínez-Guardado I, Navarro-Jiménez E, et al. The role of adipokines in health and disease. Biomedicines. 2023;11(5):1290.

Article  PubMed  PubMed Central  Google Scholar 

Zorena K, Jachimowicz-Duda O, Ślęzak D, Robakowska M, Mrugacz M. Adipokines and obesity. Potential link to metabolic disorders and chronic complications. Int J Mol Sci. 2020;21(10):3570.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lee SW, Son JY, Kim JM, Hwang S, Han JS, Heo NJ. Body fat distribution is more predictive of all-cause mortality than overall adiposity. Diabetes Obes Metab [Internet]. 2018;20(1):141–7. Available from: https://onlinelibrary.wiley.com/doi/https://doi.org/10.1111/dom.13050

Sattar N, Gill JMR. Type 2 diabetes as a disease of ectopic fat? BMC Med. 2014;12(1).

Abraham TM, Pedley A, Massaro JM, Hoffmann U, Fox CS. Association between visceral and subcutaneous adipose depots and incident cardiovascular disease risk factors. Circulation. 2015;132(17):1639–47.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ruiz-Castell M, Samouda H, Bocquet V, Fagherazzi G, Stranges S, Huiart L. Estimated visceral adiposity is associated with risk of cardiometabolic conditions in a population based study. Sci Rep. 2021;11(1).

Tallis J, James RS, Seebacher F. The effects of obesity on skeletal muscle contractile function. Journal of Experimental Biology. Volume 221. Company of Biologists Ltd; 2018.

Lee JH, Jun HS. Role of myokines in regulating skeletal muscle mass and function. Frontiers in Physiology. Volume 10. Frontiers Media S.A.; 2019.

Kim SR, Lee G, Choi S, Oh YH, Son JS, Park M, et al. Changes in predicted lean body mass, appendicular skeletal muscle mass, and body fat mass and cardiovascular disease. J Cachexia Sarcopenia Muscle. 2022;13(2):1113–23.

Article  PubMed  PubMed Central  Google Scholar 

Gu X, Wang L, Liu S, Shan T. Adipose tissue adipokines and lipokines: functions and regulatory mechanism in skeletal muscle development and homeostasis. Clinical and experimental. Volume 139. Metabolism: W.B. Saunders; 2023.

Google Scholar 

Messina C, Albano D, Gitto S, Tofanelli L, Bazzocchi A, Ulivieri FM, et al. Body composition with dual energy X-ray absorptiometry: from basics to new tools. Quantitative Imaging in Medicine and Surgery. Volume 10. AME Publishing Company; 2020. pp. 1687–98.

Shepherd JA, Ng BK, Sommer MJ, Heymsfield SB. Body composition by DXA. Bone. 2017;104:101–5.

Article  PubMed  PubMed Central  Google Scholar 

da Costa RF, Nogueira RC, Fisberg M, Ferrari G, Editorial. Body composition assessment techniques in clinical and epidemiological settings: Development, validation and use in dietary programs, physical training and sports. Front Nutr [Internet]. 2023;10(5). Available from: https://www.frontiersin.org/articles/https://doi.org/10.3389/fnut.2023.1146553/full

Faron A, Sprinkart AM, Kuetting DLR, Feisst A, Isaak A, Endler C et al. Body composition analysis using CT and MRI: intra-individual intermodal comparison of muscle mass and myosteatosis. Sci Rep. 2020;10(1).

Kuriyan R. Body composition techniques. Indian Journal of Medical Research. Volume 148. Wolters Kluwer Medknow; 2018. pp. 648–58.

Jensen B, Braun W, Geisler C, Both M, Klückmann K, Müller MJ, et al. Limitations of fat-free mass for the assessment of muscle mass in obesity. Obes Facts. 2019;12(3):307–15.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bosy-Westphal A, Jensen B, Braun W, Pourhassan M, Gallagher D, Müller MJ. Quantification of whole-body and segmental skeletal muscle mass using phase-sensitive 8-electrode medical bioelectrical impedance devices. Eur J Clin Nutr. 2017;71(9):1061–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bosy-Westphal A, Schautz B, Later W, Kehayias JJ, Gallagher D, Müller MJ. What makes a BIA equation unique? Validity of eight-electrode multifrequency BIA to estimate body composition in a healthy adult population. Eur J Clin Nutr. 2013;67:S14–21.

Article  PubMed  Google Scholar 

Ward LC, Brantlov S. Bioimpedance basics and phase angle fundamentals. Reviews in Endocrine and Metabolic Disorders. Volume 24. Springer; 2023. pp. 381–91.

Cancello R, Brunani A, Brenna E, Soranna D, Bertoli S, Zambon A, et al. Phase angle (PhA) in overweight and obesity: evidence of applicability from diagnosis to weight changes in obesity treatment. Reviews in Endocrine and Metabolic Disorders. Volume 24. Springer; 2023. pp. 451–64.

Rosero R, González C, Polanco J, Eraso-Checa F. Identificación de variables antropométricas para determinación de Índice de Masa Grasa como herramienta diagnóstica en Obesidad. Revista Colombiana de Endocrinología, Diabetes & Metabolismo. 2022;9(4).

Neeland IJ, Poirier P, Després JP. Cardiovascular and metabolic heterogeneity of obesity: clinical challenges and implications for management. Circulation. 2018;137(13):1391–406.

Article  PubMed  PubMed Central  Google Scholar 

Cifuentes L, Ghusn W, Feris F, Campos A, Sacoto D, De la Rosa A, et al. Phenotype tailored lifestyle intervention on weight loss and cardiometabolic risk factors in adults with obesity: a single-centre, non-randomised, proof-of-concept study. EClinicalMedicine. 2023;58:101923.

Article  PubMed  PubMed Central  Google Scholar 

Lin X, Li H, Obesity. Epidemiology, pathophysiology, and therapeutics. Frontiers in Endocrinology. Volume 12. Frontiers Media S.A.; 2021.

Acosta A, Camilleri M, Abu Dayyeh B, Calderon G, Gonzalez D, McRae A, et al. Selection of antiobesity medications based on phenotypes enhances weight loss: A pragmatic trial in an obesity clinic. Obesity. 2021;29(4):662–71.

Article  PubMed  Google Scholar 

Ghusn W, Cifuentes L, Anazco D, Fansa S, Tama E, Campos A, et al. Cumulative effect of obesity phenotypes on body weight and body mass index. Int J Obes. 2024;48(6):884–90.

Article  Google Scholar 

Acosta A, Camilleri M, Shin A, Carlson P, Burton D, O’Neill J, et al. Association of melanocortin 4 receptor gene variation with satiation and gastric emptying in overweight and obese adults. Genes Nutr. 2014;9(2):384.

Article  PubMed  PubMed Central  Google Scholar 

Rosero RJ, Polanco JP, Ciro V, Uribe A, Manrique H, Sánchez PE. Proposal for a Multidisciplinary Clinical Approach to Obesity. Journal of Medical– Clinical Research & Reviews [Internet]. 2020;4(12):1047–60. Available from: https://scivisionpub.com/pdfs/proposal-for-a-multidisciplinary-clinical-approach-to-obesity-1462.pdf

Keller M, Svensson SIA, Rohde-Zimmermann K, Kovacs P, Böttcher Y. Genetics and epigenetics in obesity: what do we know so far?? Curr Obes Rep. 2023;12(4):482–501.

Article  PubMed  PubMed Central  Google Scholar 

Mahmoud R, Kimonis V, Butler MG. Genetics of obesity in humans: A clinical review. Int J Mol Sci. 2022;23(19):11005.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Novelli G, Cassadonte C, Sbraccia P, Biancolella M. Genetics: A starting point for the prevention and the treatment of obesity. Nutrients. 2023;15(12):2782.

Article  CAS  PubMed