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MiThyCA: A Computational Pathology Pipeline for the Identification of Microscopic Foci of Papillary Thyroid Carcinoma-Like Nuclear Features with AI in Whole-Slide Histological Images
MiThyCA: A Computational Pathology Pipeline for the Identification of Microscopic Foci of Papillary Thyroid Carcinoma-Like Nuclear Features with AI in Whole-Slide Histological Images
The histological identification of papillary thyroid carcinoma (PTC) is straightforward for experienced endocrine patholog...
Pituitary Neuroendocrine Tumor or Pituitary Adenoma? Let’s Ask the Epigenome!
Pituitary Neuroendocrine Tumor or Pituitary Adenoma? Let’s Ask the Epigenome!
The introduction of the term pituitary neuroendocrine tumor (PitNET) to replace pituitary adenoma has sparked a versatile ...
Performance of Immunohistochemistry to Detect Rb/p53 Alterations in High-Grade Neuroendocrine Neoplasms: Staining Patterns and Comparison with Genetic Testing
Performance of Immunohistochemistry to Detect Rb/p53 Alterations in High-Grade Neuroendocrine Neoplasms: Staining Patterns and Comparison with Genetic Testing
Rb and p53 status helps distinguishing well from poorly differentiated high-grade neuroendocrine neoplasms (HG-NENs) and m...
Follicular Thyroid Carcinoma Relapse Cases - Revisited by X-ray 3D Virtual Histology
Follicular Thyroid Carcinoma Relapse Cases - Revisited by X-ray 3D Virtual Histology
The diagnosis and prognosis of follicular thyroid neoplasms are based on the identification of capsular and vascular invas...
The Utility of Cabozantinib in the Therapy of Endocrine Tumours
The Utility of Cabozantinib in the Therapy of Endocrine Tumours
Endocrine and neuroendocrine malignancies, including epithelial neuroendocrine neoplasms (NENs), phaeochromocytoma/paragan...
Correction to: Molecular Subtypes of Pancreatic Neuroendocrine Tumors Mutated in Explain Biological Variability
Correction to: Molecular Subtypes of Pancreatic Neuroendocrine Tumors Mutated in Explain Biological Variability
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Multi-center Assessment of DLL3 Expression by Immunohistochemistry in Medullary Thyroid Carcinoma
Multi-center Assessment of DLL3 Expression by Immunohistochemistry in Medullary Thyroid Carcinoma
Medullary thyroid carcinoma (MTC) is a rare neuroendocrine malignancy accounting for 1–2% of thyroid carcinomas. As ...
Quantitative Assessment of Focus Quality in Whole-Slide Imaging of Thyroid Liquid-Based Cytology Using Laplacian Variance
Quantitative Assessment of Focus Quality in Whole-Slide Imaging of Thyroid Liquid-Based Cytology Using Laplacian Variance
Reliable focus is essential for digital cytopathology, yet three-dimensional cell clusters in liquid-based cytology (LBC) ...
Adult Pancreatoblastoma: A Challenge in the Differential Diagnosis of Pancreatic Neuroendocrine Neoplasms
Adult Pancreatoblastoma: A Challenge in the Differential Diagnosis of Pancreatic Neuroendocrine Neoplasms
Authors and AffiliationsDepartment of Biomedical Sciences, Humanitas University, Milan, ItalyVincenzo Guastafierro, Saveri...
Book Review: AFIP Atlases of Tumor and Non-tumor Pathology Series 5, Fascicle 21: Tumors of the Adrenal Glands and Extra-adrenal Paraganglia by Ronald R. de Krijger, Arthur S. Tischler, Sylvia L. Asa, Ernest E. Lack, Marco Volante
Book Review: AFIP Atlases of Tumor and Non-tumor Pathology Series 5, Fascicle 21: Tumors of the Adrenal Glands and Extra-adrenal Paraganglia by Ronald R. de Krijger, Arthur S. Tischler, Sylvia L. Asa, Ernest E. Lack, Marco Volante
Cite this articleMete, O. Book Review: AFIP Atlases of Tumor and Non-tumor Pathology Series 5, Fascicle 21: Tumors of the ...
Insights into Biologic Evolution of Grade 3 Neuroendocrine Tumors Reflect Classification Challenges
Insights into Biologic Evolution of Grade 3 Neuroendocrine Tumors Reflect Classification Challenges
In the IARC/WHO classification framework of neuroendocrine neoplasms (NENs), high-gra...
Evaluating CK20 and MCPyV Antibody Clones in Diagnosing Merkel Cell Carcinoma
Evaluating CK20 and MCPyV Antibody Clones in Diagnosing Merkel Cell Carcinoma
Merkel cell carcinoma (MCC) is diagnosed through histopathological and immunohistochemical examination of biopsies from sk...
Deep Learning Enabled Scoring of Pancreatic Neuroendocrine Tumors Based on Cancer Infiltration Patterns
Deep Learning Enabled Scoring of Pancreatic Neuroendocrine Tumors Based on Cancer Infiltration Patterns
Pancreatic neuroendocrine tumors (PanNETs) are a heterogeneous group of neoplasms that include tumors with different histo...
Clinical Relevance of Gene Mutations and ALT in Functioning Pancreatic Neuroendocrine Tumors
Clinical Relevance of Gene Mutations and ALT in Functioning Pancreatic Neuroendocrine Tumors
Functioning pancreatic neuroendocrine tumors (PanNETs) represent a subset of PanNETs that cause symptoms due to hormonal a...
Comprehensive Gene Expression Analysis in Papillary Thyroid Carcinoma Reveals a Transcriptional Profile Associated with Reduced Radioiodine Avidity
Comprehensive Gene Expression Analysis in Papillary Thyroid Carcinoma Reveals a Transcriptional Profile Associated with Reduced Radioiodine Avidity
Papillary thyroid carcinoma (PTC) is the most common form of well-differentiated thyroid cancer (WDTC) and generally has a...
Identification of Oncogenic Alterations in 124 Cases of Pediatric Papillary Thyroid Carcinoma: ::, ::, and :: Fusions Induce MAPK Pathway Activation
Identification of Oncogenic Alterations in 124 Cases of Pediatric Papillary Thyroid Carcinoma: ::, ::, and :: Fusions Induce MAPK Pathway Activation
Pediatric papillary thyroid carcinoma (PPTC; under age 18 at the time of diagnosis) is relatively uncommon. There are few ...
Methylation Profiles Differ According to Clinical Characteristics in Well-Differentiated Neuroendocrine Tumors of the Lung
Methylation Profiles Differ According to Clinical Characteristics in Well-Differentiated Neuroendocrine Tumors of the Lung
Neuroendocrine tumors (NET) of the lung constitute a rare entity of primary lung malignancies that often exhibit an indole...
Refining Fusion Detection in Papillary Thyroid Carcinoma Through Pan-TRK Immunohistochemistry and Histopathologic Features
Refining Fusion Detection in Papillary Thyroid Carcinoma Through Pan-TRK Immunohistochemistry and Histopathologic Features
NTRK fusions are rare but recurrent driver alterations in papillary thyroid carcinoma (PTC), with therapeutic significance...
Next-Generation Immunohistochemistry in Thyroid Neoplasm: A Practical Review on the Applications in Diagnosis and Molecular Classification
Next-Generation Immunohistochemistry in Thyroid Neoplasm: A Practical Review on the Applications in Diagnosis and Molecular Classification
An integrative histologic and molecular classification of thyroid tumors has become clinically relevant due to the potenti...
DLL3 Expression in Neuroendocrine Carcinomas and Neuroendocrine Tumours: Insights From a Multicentric Cohort of 1294 Pulmonary and Extrapulmonary Neuroendocrine Neoplasms
DLL3 Expression in Neuroendocrine Carcinomas and Neuroendocrine Tumours: Insights From a Multicentric Cohort of 1294 Pulmonary and Extrapulmonary Neuroendocrine Neoplasms
Delta-like ligand 3 (DLL3) is frequently expressed in pulmonary small cell neuroendocrine carcinoma (SCNEC) and has emerge...
Multicentric Retrospective Analysis of Oncocytic Adrenocortical Carcinoma: Insights into Clinical and Management Strategies
Multicentric Retrospective Analysis of Oncocytic Adrenocortical Carcinoma: Insights into Clinical and Management Strategies
Oncocytic adrenocortical carcinoma (OAC) is a rare variant of conventional adrenocortical carcinoma (ACC), characterized b...
Prevalence and Clinical Impact of p.V600E Mutation in Papillary Thyroid Carcinoma
Prevalence and Clinical Impact of p.V600E Mutation in Papillary Thyroid Carcinoma
Identifying risk factors in papillary thyroid carcinoma (PTC) that warrant more aggressive treatment is paramount. Importa...
Identification of Specific Biomarkers for Anaplastic Thyroid Carcinoma Through Spatial Transcriptomic and Immunohistochemical Profiling
Identification of Specific Biomarkers for Anaplastic Thyroid Carcinoma Through Spatial Transcriptomic and Immunohistochemical Profiling
Anaplastic thyroid carcinoma (ATC) is an aggressive malignancy with a poor prognosis. Despite its rarity, identifying pred...
Amplification a Risk Stratification Marker in Papillary Thyroid Carcinoma, Significantly Correlated with Tumor Recurrence and Survival
Amplification a Risk Stratification Marker in Papillary Thyroid Carcinoma, Significantly Correlated with Tumor Recurrence and Survival
Few studies have analyzed the prevalence of TERT amplification in thyroid cancer, showing discrepancies in various topics....
Is Ectopic Cushing Syndrome Commonly Associated with Small Cell Lung Cancer (SCLC)? Critical Review of the Literature and ACTH Expression in Resected SCLC
Is Ectopic Cushing Syndrome Commonly Associated with Small Cell Lung Cancer (SCLC)? Critical Review of the Literature and ACTH Expression in Resected SCLC
The literature emphasizes that pulmonary ectopic Cushing syndrome (ECS) is associated not only with neuroendocrine tumors ...
ABCC3 Is a Differential Marker of CYP11B2-Negative Zona Glomerulosa Cells in Human Adrenal Cortex
ABCC3 Is a Differential Marker of CYP11B2-Negative Zona Glomerulosa Cells in Human Adrenal Cortex
ATP Binding Cassette Subfamily C Member 3 (ABCC3) is a membrane transporter that exports diverse compounds, influencing dr...
Clinicopathological Correlates of Hormone Expression-Based Subtypes of Non-Functioning Duodenal/Ampullary Neuroendocrine Tumors: A Multicenter Study of 151 Cases
Clinicopathological Correlates of Hormone Expression-Based Subtypes of Non-Functioning Duodenal/Ampullary Neuroendocrine Tumors: A Multicenter Study of 151 Cases
Duodenal neuroendocrine tumors (Duo-NETs) may arise in the ampullary and non-ampullary duodenum. Non-functioning Duo-NETs ...
Three Synchronous Pituitary Neuroendocrine Tumors—Epigenomics Confirm an Exceptional Triple PitNET
Three Synchronous Pituitary Neuroendocrine Tumors—Epigenomics Confirm an Exceptional Triple PitNET
Histopathology revealed three distinct tumor components (Fig. 1C). The first component was characterized by scant infiltra...
Clinical and Molecular Characteristics of Gonadotroph Pituitary Tumors According to the WHO Classification
Clinical and Molecular Characteristics of Gonadotroph Pituitary Tumors According to the WHO Classification
Since 2017, hormone-negative pituitary neuroendocrine tumors expressing the steroidogenic factor SF1 have been recognized ...
Artificial Intelligence Detected the Relationship Between Nuclear Morphological Features and Molecular Abnormalities of Papillary Thyroid Carcinoma
Artificial Intelligence Detected the Relationship Between Nuclear Morphological Features and Molecular Abnormalities of Papillary Thyroid Carcinoma
Papillary thyroid carcinoma (PTC) is the most common type of thyroid carcinoma and has characteristic nuclear features. Ge...
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