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Vitamin D receptor suppresses pulmonary fibroblast activation by downregulating the TGF-β1/Smad signaling pathway
Vitamin D receptor suppresses pulmonary fibroblast activation by downregulating the TGF-β1/Smad signaling pathway
The vitamin D receptor (VDR) has been implicated in anti-inflammatory and antifibrotic effects, but its role in r...
Relationships between clusters of interchromatin granules and chromatin fibers
Relationships between clusters of interchromatin granules and chromatin fibers
Among nuclear compartments, interchromatin granule clusters (IGCs) are widely regarded as biomolecular condensates implica...
Follicle-dependent differential localization of adipokines in the letrozole-induced hyperandrogenized mouse ovary
Follicle-dependent differential localization of adipokines in the letrozole-induced hyperandrogenized mouse ovary
This study investigated whether ovarian adipokines exhibit uniform or stage-specific expression patterns across different ...
Electric field–induced inflammatory and angiogenic responses in rat female reproductive tissues: evidence for early extracellular matrix remodeling
Electric field–induced inflammatory and angiogenic responses in rat female reproductive tissues: evidence for early extracellular matrix remodeling
High-intensity electric fields (EFs) are increasingly encountered in occupational and environmental settings, raising conc...
February in focus in HCB: spatial transcriptomics
February in focus in HCB: spatial transcriptomics
Welcome to the February 2026 In focus in HCB editorial. In this editorial we will highlight one recent manuscript utilizin...
Time-dependent integrated tissue and circulating biomarker dynamics of spexin and progranulin in an experimental myocardial infarction model
Time-dependent integrated tissue and circulating biomarker dynamics of spexin and progranulin in an experimental myocardial infarction model
Inflammation, oxidative stress and apoptosis, in particular, play critical roles in the pathophysiology of myocardial infa...
Histochemical characterization of muscularis macrophage loss and disruption of a miR-93-5p–AHNAK neuro-immune axis in Hirschsprung’s disease
Histochemical characterization of muscularis macrophage loss and disruption of a miR-93-5p–AHNAK neuro-immune axis in Hirschsprung’s disease
Hirschsprung’s disease (HSCR) is a congenital disorder of the distal intestine characterized by aganglionosis of the...
Targeting SAT1 alleviates high glucose-induced tubular ferroptosis and fibrosis: implications for diabetic kidney disease
Targeting SAT1 alleviates high glucose-induced tubular ferroptosis and fibrosis: implications for diabetic kidney disease
Renal tubular damage and interstitial fibrosis are highly linked to diabetic kidney disease (DKD) progression. Ferroptosis...
Fibre morphology, intramyocellular lipid content and 3D capillary architecture in human postural, respiratory and locomotor muscles in type 2 diabetes mellitus
Fibre morphology, intramyocellular lipid content and 3D capillary architecture in human postural, respiratory and locomotor muscles in type 2 diabetes mellitus
In type 2 diabetes mellitus (T2DM), skeletal muscle is a major site of metabolic and microvascular dysfunction, yet most h...
Periostin in joint physiology and pathology: multiple roles from mechanisms to clinical perspectives
Periostin in joint physiology and pathology: multiple roles from mechanisms to clinical perspectives
Joint-related diseases, including osteoarthritis (OA), rheumatoid arthritis (RA), intervertebral disc degeneration (IDD), ...
ER stress affects proliferation and induces polyploidization of cultured human HaCaT and A431 cells
ER stress affects proliferation and induces polyploidization of cultured human HaCaT and A431 cells
Endoplasmic reticulum (ER) stress is the accumulation of misfolded or defective proteins in the ER. ER stress is capable o...
Fiber type-specific expression of LACTB leverages a function in oxidative metabolism
Fiber type-specific expression of LACTB leverages a function in oxidative metabolism
Skeletal muscle is composed of type I and type II fibers, each characterized by specific metabolic machinery. LACTB is a c...
Functional suppression accompanies internal mitochondrial reorganization during cellular reprogramming
Functional suppression accompanies internal mitochondrial reorganization during cellular reprogramming
During the conversion of fibroblasts into induced pluripotent stem cells (iPSCs), cellular metabolism shifts from oxidativ...
Oncogenic overexpression of kallikrein-related peptidase 7 is associated with the progression of thyroid cancer
Oncogenic overexpression of kallikrein-related peptidase 7 is associated with the progression of thyroid cancer
Mounting evidence suggests that the kallikrein-related peptidase family is dysregulated in thyroid cancer. However, previo...
Localization of dendritic cells and T cells within the tumor microenvironment in different types of skin cancer
Localization of dendritic cells and T cells within the tumor microenvironment in different types of skin cancer
Immunophenotyping of tumor-infiltrating immune cells is increasingly important for understanding the tumor microenvironmen...
SASP-driven vascular aging: unraveling the transcriptional nexus in endothelial senescence and cardiovascular disease
SASP-driven vascular aging: unraveling the transcriptional nexus in endothelial senescence and cardiovascular disease
Endothelial cell senescence represents a critical mechanistic driver in the initiation and progression of cardiovascular d...
Effects of obesity on DNA methylation and DNA methyltransferases in the reproductive system
Effects of obesity on DNA methylation and DNA methyltransferases in the reproductive system
Obesity is increasingly recognized as a condition with profound systemic and epigenetic consequences. However, the molecul...
Approaches to visualize, quantify, and manipulate phosphoinositides in cells
Approaches to visualize, quantify, and manipulate phosphoinositides in cells
Phosphoinositides are low-abundance regulatory lipids that control a broad range of cellular processes, from membrane traf...
Methodological framework for chromogenic mRNA detection using in situ hybridization chain reaction
Methodological framework for chromogenic mRNA detection using in situ hybridization chain reaction
In situ hybridization chain reaction (HCR) is a highly sensitive method for visualizing single-molecule messenger RNA (mRN...
Assessment of strain-dependent variation of phytostimulatory activity in Streptomyces ambofaciens-based bioformulations for agricultural applications
Assessment of strain-dependent variation of phytostimulatory activity in Streptomyces ambofaciens-based bioformulations for agricultural applications
Andriuschenko, O. V., Strashnova, I. V., Ivanytsia, T. V., Rakytska, S. I., & Galkin, M. B. (202...
Kinetic properties of glutathione-S-transferase in prostate gland biopsies of patients with benign prostatic hyperplasia and chronic prostatitis
Kinetic properties of glutathione-S-transferase in prostate gland biopsies of patients with benign prostatic hyperplasia and chronic prostatitis
Alnasser, S. M. (2024). The role of glutathione S-transferases in human disease pathogenesis and the...
Microstructure of goat milk
Microstructure of goat milk
Ali, M. E., Abdelrahman, M., Zakaria, A. M., Farag, B. F., Mohamed, R. H., Fayed, H., El-Hamid, I. S...
Phytoindication assessment of spatial patterns of ecological regimes in urban parks as a basis for ecologically relevant management
Phytoindication assessment of spatial patterns of ecological regimes in urban parks as a basis for ecologically relevant management
Bai, J., Wang, Y., & Chang, Q. (2024). Cultural ecosystem services of urban green space for huma...
Physiological responses of microclonally propagated willow to excessive levels of UV-B radiation
Physiological responses of microclonally propagated willow to excessive levels of UV-B radiation
Ali, A., Santoro, P., Mori, J., Ferrante A., & Cocetta, G. (2024). Effect of UV-B elicitation on...
Influence of microorganisms of fleece on the structure, physical properties, amino acid and mineral composition of sheep wool
Influence of microorganisms of fleece on the structure, physical properties, amino acid and mineral composition of sheep wool
Bergendal, E., Batista, M., Luengo, G. S., & Rutland, M. W. (2025). Self-assembly induced patter...
Effects of insulin-like growth factor-1 and fibroblast growth factor-2 on the in vitro maturation of bovine oocytes
Effects of insulin-like growth factor-1 and fibroblast growth factor-2 on the in vitro maturation of bovine oocytes
Artini, P. G., Tatone, C., Sperduti, S., D'Aurora, M., Franchi, S., Di Emidio, G., Ciriminna, R., Ve...
Clinical and diagnostic significance of oxidative stress in post-COVID olfactory dysfunction associated with acute rhinosinusitis
Clinical and diagnostic significance of oxidative stress in post-COVID olfactory dysfunction associated with acute rhinosinusitis
Amer, S. A., Al-Zahrani, A., Imam, E. A., Ishteiwy, E. M., Djelleb, I. F., Abdullh, L. R., Ballaj, D...
Comprehensive phytochemical and antioxidant evaluation of Salvia officinalis via in vitro and in silico analyses, ADME prediction
Comprehensive phytochemical and antioxidant evaluation of Salvia officinalis via in vitro and in silico analyses, ADME prediction
Ahmed, F., Akter, D., Muhit, M. A., Raihan, S. Z., & Faroque, A. B. M. (2018). DPPH free-radical...
The interaction between cytokine profiles and Epstein-Barr virus-induced immune response
The interaction between cytokine profiles and Epstein-Barr virus-induced immune response
Ajeed, A. M., Naif, N. H., Farag, A. H., & Mohsein, O. A. (2025). Assessing the impact of sleeve...
Adiponectin, leptin, and novel adipokines (resistin, visfatin, omentin) as biomarkers of metabolic and immune dysregulation in type 1 diabetes
Adiponectin, leptin, and novel adipokines (resistin, visfatin, omentin) as biomarkers of metabolic and immune dysregulation in type 1 diabetes
Abdalla, M. M. I. (2024). Therapeutic potential of adiponectin in prediabetes: Strategies, challenge...
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