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White adipose tissue undergoes pathological dysfunction in the TDP-43A315T mouse model of amyotrophic lateral sclerosis (ALS)
White adipose tissue undergoes pathological dysfunction in the TDP-43A315T mouse model of amyotrophic lateral sclerosis (ALS)
White adipose tissue (WAT) has a crucial role in maintaining systemic energy homeostasis. Numerous biological pathway stud...
Ablation of progranulin augments microglial activation and accelerates prion progression
Ablation of progranulin augments microglial activation and accelerates prion progression
Mutations or polymorphisms in GRN, encoding the CNS glycoprotein progranulin (PGRN), have been linked to several neurodege...
Inflammation of central nervous system fiber tracts is active in patients over six months post-intracerebral hemorrhage
Inflammation of central nervous system fiber tracts is active in patients over six months post-intracerebral hemorrhage
The occurrence and extent of central nervous system (CNS) fiber tract inflammation in chronic-phase intracerebral hemorrha...
Pharmacological inhibition of SPAK-NKCC1 complex attenuates astrogliosis and restores cerebral blood flow in a mouse model of VCID
Pharmacological inhibition of SPAK-NKCC1 complex attenuates astrogliosis and restores cerebral blood flow in a mouse model of VCID
Vascular contributions to cognitive impairment and dementia (VCID) are one of the leading causes of dementia, where reacti...
Differentiation to insulin-positive cells from human amnion epithelial cells using a pancreatic development mimicry protocol
Differentiation to insulin-positive cells from human amnion epithelial cells using a pancreatic development mimicry protocol
Diabetes mellitus (DM) is characterized by the loss or dysfunction pancreatic β-cells. Human amniotic epithelial cell...
Excessive intake of fructose and alcohol aggravates high-fat diet-induced steatohepatitis and changes hepatic iron homeostasis
Excessive intake of fructose and alcohol aggravates high-fat diet-induced steatohepatitis and changes hepatic iron homeostasis
Hepatocytes play a vital role in maintaining iron homeostasis, which can be compromised by poor diet and lifestyle. This s...
The ILK–PINCH–parvin complex: a conserved primary adhesome regulating biological processes
The ILK–PINCH–parvin complex: a conserved primary adhesome regulating biological processes
Intracellularly expressed integrin associated proteins (IAPs) play pivotal role in facilitating cellular adhesion and surv...
Exploring the expression of MMP-2, MT1-MMP, and MMP-9 in the pectoral muscle of Ross chickens during E11, E15, and E19 of fetal development
Exploring the expression of MMP-2, MT1-MMP, and MMP-9 in the pectoral muscle of Ross chickens during E11, E15, and E19 of fetal development
There are pertinent studies on the relationship between matrix metalloproteinases (MMPs) and muscle cell differentiation i...
Secreted Frizzled-related proteins in animal development
Secreted Frizzled-related proteins in animal development
Secreted Frizzled-related proteins (SFRPs) are a small, ancient family of extracellular signaling pathway agonists and ant...
Development of optimized differentiation media for murine bone marrow multipotent mesenchymal stromal cells
Development of optimized differentiation media for murine bone marrow multipotent mesenchymal stromal cells
Here, we aimed to define adipogenic, osteogenic, and chondrogenic media for the differentiation of murine mesenchymal stro...
Comparative assessment of human chondroprogenitor viability and molecular phenotype in various parenteral transport media
Comparative assessment of human chondroprogenitor viability and molecular phenotype in various parenteral transport media
Chondroprogenitors derived from articular cartilage offer a promising approach for treating cartilage pathologies owing to...
Proneural gene Mash1 (Ascl1) is expressed in multiple lineages and regulates their differentiation and specification
Proneural gene Mash1 (Ascl1) is expressed in multiple lineages and regulates their differentiation and specification
Ascl1 (Mash1), a bHLH transcription factor, is widely expressed by neuronal progenitors. The gene plays a key role in the ...
The first link between ADAMTS-13 and apoptosis in type 1 diabetic liver injury
The first link between ADAMTS-13 and apoptosis in type 1 diabetic liver injury
Type 1 diabetes mellitus (T1DM) is associated with oxidative stress and inflammation in the liver, which contribute to hep...
Telocytes: history, origin, identification, structure, distribution, and functions
Telocytes: history, origin, identification, structure, distribution, and functions
Telocytes are specialized interstitial cells characterized by their unique structure, which features a relatively small ce...
Combined treatment of melatonin and alpha-lipoic acid facilitates wound healing in rat palate: A macroscopic, histological, and immunohistochemical study
Combined treatment of melatonin and alpha-lipoic acid facilitates wound healing in rat palate: A macroscopic, histological, and immunohistochemical study
Oxidative stress is known to have a detrimental effect on wound healing following oral mucosal injuries. Exogenous antioxi...
MyoAnalyst: an ImageJ plugin for accurate and automatic myofiber segmentation and analysis in skeletal muscle cross sections
MyoAnalyst: an ImageJ plugin for accurate and automatic myofiber segmentation and analysis in skeletal muscle cross sections
Quantifying myofiber size is essential for assessing the health and function of skeletal muscle. Although several ImageJ p...
July in focus in HCB
July in focus in HCB
The inhibitor of growth protein family (ING) consists of at least five family members (ING1–5), with a range of proposed a...
Increased Fos immunoreactivity in astrocytes in the raphe pallidus under hypoxia, not hypercapnia
Increased Fos immunoreactivity in astrocytes in the raphe pallidus under hypoxia, not hypercapnia
The raphe pallidus (RPa), a part of the caudal medullary raphe nucleus, has been suggested to participate in respiratory r...
Unveiling the intricacies of exosome biology: from biogenesis to therapeutic applications
Unveiling the intricacies of exosome biology: from biogenesis to therapeutic applications
Exosomes are small membrane-bound nanovesicles that are secreted by cells when multivesicular bodies merge with the plasma...
Gamma smooth muscle actin as a new potential marker of cancer-associated fibroblasts
Gamma smooth muscle actin as a new potential marker of cancer-associated fibroblasts
Cancer-associated fibroblasts (CAFs) represent an important component of the cancer ecosystem, influencing the broad scale...
Effects of extenders on the functional activity of chilled canine spermatozoa during prolonged storage
Effects of extenders on the functional activity of chilled canine spermatozoa during prolonged storage
Álvarez-Rodríguez, M., Nieto-Cristobal, H., & de Mercado, E. (2024). Bovine serum albumin inclus...
Post-harvest application of biological residue decomposers and mulching: Effects on soil health and winter wheat yield
Post-harvest application of biological residue decomposers and mulching: Effects on soil health and winter wheat yield
Bardgett, R. D., & Caruso, T. (2020). Soil microbial community responses to climate extremes: Re...
Histological and ultramicroscopic features of the liver of Hypophthalmichthys nobilis
Histological and ultramicroscopic features of the liver of Hypophthalmichthys nobilis
Abusrer, S. A., & Shtewi, H. H. (2023). Morphological and histological structure of hepatopancre...
The role of GNAS1 gene polymorphisms in development of bladder and prostate cancer: A case–control study
The role of GNAS1 gene polymorphisms in development of bladder and prostate cancer: A case–control study
Arjumand, W., Ahmad, S. T., Nafees, S., Ali, N., Rashid, S., Seth, A., & Sultana, S. (2012). GNA...
A medical drug based on fipronil, dinotefuran, and pyriproxyfen for treatment of ectoparasitic infestations of dogs and cats
A medical drug based on fipronil, dinotefuran, and pyriproxyfen for treatment of ectoparasitic infestations of dogs and cats
Authoy, A. S., Chanda, A., Datta, A., Al Faruk, S., & Kamal, T. (2023). Prevalence of ectoparasi...
Sorptive properties of hydrogel dressings and their antimicrobial action after saturation with tetracyclines
Sorptive properties of hydrogel dressings and their antimicrobial action after saturation with tetracyclines
Anghel, I., Holban, A. M., Grumezescu, A. M., Andronescu, E., Ficai, A., Anghel, A. G., Maganu, M., ...
Bacterial strains isolated from sinusitis infections and their drug resistance profiles in Nasiriyah (Iraq)
Bacterial strains isolated from sinusitis infections and their drug resistance profiles in Nasiriyah (Iraq)
Alshehri, A. M. S., Assiri, O. A., Alqarni, A. M. S., Alkhairi, M. A. Y., Alzahrani, M. A. A., Alshe...
Association between IL-17A rs2275913 gene polymorphism and the levels of inflammatory markers (NFKB1 and IL-17A) in Iraqi patients with diabetic nephropathy (T2DNP)
Association between IL-17A rs2275913 gene polymorphism and the levels of inflammatory markers (NFKB1 and IL-17A) in Iraqi patients with diabetic nephropathy (T2DNP)
Afkarian, M., Sachs, M. C., Kestenbaum, B., Hirsch, I. B., Tuttle, K. R., Himmelfarb, J., & de B...
Features of the microscopic structure of the lungs of Clarias gariepinus of the catfish family
Features of the microscopic structure of the lungs of Clarias gariepinus of the catfish family
Aleksiienko, V. R. (2007). Ikhtiolohiia [Ichthyology]. Ukrainskyi Fitosotsiolohichnyi Tsentr, Kyiv (...
Clinical outcomes of concurrent use of corticosteroids and immune checkpoint inhibitors in oncology
Clinical outcomes of concurrent use of corticosteroids and immune checkpoint inhibitors in oncology
Capella, M. P., Pang, S. A., Magalhaes, M. A., & Esfahani, K. (2024). A review of immunotherapy ...
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