SCI Abstract

search
+
[Genetics] William Castle's Guinea Pigs and the Spread of Mendelian Teaching
A new type of review journal, featuring comprehensive collections of expert review articles on important topics in the mol...
[Developmental Biology] Collective Cell Migration Strategies: Patterning, Motility, and Directionality of the Posterior Lateral Line Primordium in Zebrafish
A new type of review journal, featuring comprehensive collections of expert review articles on important topics in the mol...
[Molecular Biology] Regulation of Human Telomerase: From Molecular Interactions to Population Genetics
A new type of review journal, featuring comprehensive collections of expert review articles on important topics in the mol...
[Cell Biology] Ca2+ Fluxes across Membrane Contact Sites
A new type of review journal, featuring comprehensive collections of expert review articles on important topics in the mol...
[Molecular Biology] Mechanisms and Determinants of -1 Ribosome Frameshifting and Bypassing
A new type of review journal, featuring comprehensive collections of expert review articles on important topics in the mol...
Single-Cell Transcriptomics Identifies a Pivotal Role of SPHK1 Macrophage-Driven Inflammation in Mechanism of Aortic Dissection and Highlights SPHK1 as a Therapeutic Target
Single-Cell Transcriptomics Identifies a Pivotal Role of SPHK1 Macrophage-Driven Inflammation in Mechanism of Aortic Dissection and Highlights SPHK1 as a Therapeutic Target
Macrophages are a key heterogeneous cell population involved in the pathogenesis and progression of acute aortic dissectio...
Adipose-Derived Proinflammatory Visfatin Promotes Vascular Calcification via TLR4 and is Suppressed by Empagliflozin
Adipose-Derived Proinflammatory Visfatin Promotes Vascular Calcification via TLR4 and is Suppressed by Empagliflozin
Vascular calcification, a common complication of metabolic diseases such as diabetes and obesity, is closely associated wi...
Dendritic Cells Derived MMP9 Fuels Sepsis-Induced Cardiac Dysfunction Through JNK/AP1 Driven Pro-Inflammatory Cytokine and Nitric Oxide Storm
Dendritic Cells Derived MMP9 Fuels Sepsis-Induced Cardiac Dysfunction Through JNK/AP1 Driven Pro-Inflammatory Cytokine and Nitric Oxide Storm
Metalloproteinase9 is an important inflammatory mediator, but its contribution to sepsis-induced myocardial dysfunction (S...
The Histamine Four Receptor Regulates LFA-1 But Not Mac-1 -Dependent Neutrophil Adhesion and Inflammatory Functions
The Histamine Four Receptor Regulates LFA-1 But Not Mac-1 -Dependent Neutrophil Adhesion and Inflammatory Functions
Neutrophils incubated on ICAM-1- or fibrinogen- coated plates produced histamine in response to fMLP indicating that hista...
A transgene-free, human peri-gastrulation embryo model presents trilaminar embryonic disc-, amnion- and yolk sac-like structures
A transgene-free, human peri-gastrulation embryo model presents trilaminar embryonic disc-, amnion- and yolk sac-like structures
Human peri-gastrulation is a critical developmental stage, yet challenging to study directly. Stem cell-based embryo model...
SLC33A1 exports oxidized glutathione to maintain endoplasmic reticulum redox homeostasis
SLC33A1 exports oxidized glutathione to maintain endoplasmic reticulum redox homeostasis
The endoplasmic reticulum (ER) requires an oxidative environment to support the efficient maturation of secretory and memb...
A lipid-centric view of endocytosis by caveolae
A lipid-centric view of endocytosis by caveolae
Caveolae have long been considered to be an alternative endocytic pathway, with distinct cargoes, but generally similar fu...
The proteomic landscape and temporal dynamics of human and mouse gastruloid development
The proteomic landscape and temporal dynamics of human and mouse gastruloid development
The embryo establishes a body plan and primes itself for organogenesis during gastrulation. As gastrulation is challenging...
Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability
Electrophilic compound screening identifies GPX4-dependent ferroptosis as a senescence vulnerability
Senescent cells drive ageing and age-related pathologies, including cancer. Consequently, senolytics, drugs that selective...
Longitudinal localization of leukaemic stem cells between the metaphysis and central marrow governs their behaviour
Longitudinal localization of leukaemic stem cells between the metaphysis and central marrow governs their behaviour
Leukaemic stem cells (LSCs) reside in protective bone marrow (BM) niches that promote therapeutic resistance and relapse. ...
Cancer-associated fibroblasts regulate DNA repair in pancreatic cancer through NDRG1-mediated R-loop processing
Cancer-associated fibroblasts regulate DNA repair in pancreatic cancer through NDRG1-mediated R-loop processing
Pancreatic ductal adenocarcinomas (PDACs) are aggressive, stroma-rich tumours. They are unresponsive to treatments, and pa...
Somatic mutations distinguish melanocyte subpopulations in human skin
Somatic mutations distinguish melanocyte subpopulations in human skin
Here, to understand the homeostatic mechanisms governing melanocytes, we interrogate the mutational landscapes, gene-expre...
RNA binding protein SERBP1 is indispensable for oocyte development and maturation in mice
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Etomidate relieves oxaliplatin-induced neuropathic pain by regulating AMPK/Nrf2/HO-1 axis
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Glucose deprivation impairs lipid tolerance related to mitophagy disorder in cardiomyocytes
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
E-cigarette aerosol constituents modulate Leydig cell steroidogenic pathways: Evidence from experimental models
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Kinetic management of endocrine disruption: How chemical dynamics shape hormonal systems
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
FAM237B, a conserved orexigenic neuropeptide, is regulated by fasting, insulin, and neuroinflammation in mouse hypothalamic NPY/AgRP neurons
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Alpha-Klotho-deficient female mice exhibit estrogen metabolic dysregulation and a premature ovarian insufficiency–like phenotype
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
SIK1 drives lipid-induced insulin resistance in skeletal muscle by linking TGFβ1-Smad2/3 activation to PDE4-cAMP dysregulation
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
n-3 polyunsaturated fatty acids inhibit the IL-1β/SP positive feedback loop in intervertebral disc endplate and low back pain-related behaviors in mice
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Oral Honokiol-loaded solid lipid nanoparticles: A shielding nanotherapeutic strategy to attenuate STZ-induced type 1 diabetes via targeted modulation of oxidative stress and apoptotic signaling
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Corrigendum to “Differential effects of synthetic progestagens on neuron survival and estrogen neuroprotection in cultured neurons” [Mol. Cell. Endocrinol. 384 1-2 (2014) 52-60]
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Retraction notice to “Involvement of PI3 kinase and MAP kinase in IGF-I- and insulin-induced oocyte maturation in Cyprinus carpio” [Mol. Endocrinol. 309 (2009) 93-100]
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Retraction notice to “Regulation of ovarian steroidogenesis in vitro by IGF-I and insulin in common carp, Cyprinus carpio: stimulation of aromatase activity and P450arom gene expression” [Mol. Endocrinol. 315 (2010) 95-103]
All content on this site: Copyright © 2025 Elsevier B.V., its licensors, and contributors. All rights are reserved, includ...
Load More
format_indent_increase