SCI Abstract

search
+
Lithium compromises the bioenergetic reserve of cardiomyoblasts mitochondria
Lithium compromises the bioenergetic reserve of cardiomyoblasts mitochondria
Lithium is used in the long-term treatment of bipolar disorder, exhibiting a beneficial effect on the neuronal cells. The ...
Mitochondrial glutamic-oxaloacetic transaminase (GOT2) in the growth of C2C12 myoblasts
Mitochondrial glutamic-oxaloacetic transaminase (GOT2) in the growth of C2C12 myoblasts
Glutamine is well recognized as critical to the growth of most cell types. Within mitochondria glutamine is converted to g...
METTL3 mediates CPB1 expression by regulating transcription factor BACH2 to promote apoptosis and oxidative stress of lens epithelial cells
METTL3 mediates CPB1 expression by regulating transcription factor BACH2 to promote apoptosis and oxidative stress of lens epithelial cells
Background: Cataracts are a significant cause of vision loss, adversely affecting the quality of human life. Numerous stud...
Dexmedetomidine activates mitophagy and protects against pyroptosis in oxygen-glucose deprivation/reperfusion-induced brain damage PINK1/Parkin pathway activation
Dexmedetomidine activates mitophagy and protects against pyroptosis in oxygen-glucose deprivation/reperfusion-induced brain damage PINK1/Parkin pathway activation
Accumulating studies have unraveled that dexmedetomidine (DEX) is neuroprotective against brain damage. However, it remain...
Anti-inflammatory effects of Esomeprazole in septic lung injury by mediating endoplasmic reticulum stress
Anti-inflammatory effects of Esomeprazole in septic lung injury by mediating endoplasmic reticulum stress
Acute lung injury characterized by overactive pulmonary inflammation is a common and serious complication of sepsis. Esome...
Targeting hypoxia-induced HIF-1α/JMJD3/Notch axis in gastric cancer therapy
Targeting hypoxia-induced HIF-1α/JMJD3/Notch axis in gastric cancer therapy
Hypoxia has been reported to induce high expression of HIF-1α in multiple cancer tissues, and HIF-1α significant...
KunMingShanHaiTang formula reprograms macrophage metabolism and promotes M2 polarization via the HIF-1α pathway to alleviate ulcerative colitis symptoms in a rat model
KunMingShanHaiTang formula reprograms macrophage metabolism and promotes M2 polarization via the HIF-1α pathway to alleviate ulcerative colitis symptoms in a rat model
The KunMingShanHaiTang Formula (KMSHTF), adjusted by Professor Zhong Chuanhua for the treatment of ulcerative colitis (UC)...
The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer
The Warburg hypothesis and the emergence of the mitochondrial metabolic theory of cancer
Otto Warburg originally proposed that cancer arose from a two-step process. The first step involved a chronic insufficienc...
Mechanism of LncRNA CBR3-AS1 in regulating pyroptosis of intestinal epithelial cells in ulcerative colitis
Mechanism of LncRNA CBR3-AS1 in regulating pyroptosis of intestinal epithelial cells in ulcerative colitis
Ulcerative colitis (UC) is a common chronic relapsing inflammatory disease that threatens human life. This study aims to e...
Differences in metabolite profiling by cold atmospheric plasma in normal and cancer cells
Differences in metabolite profiling by cold atmospheric plasma in normal and cancer cells
Cold atmospheric plasma (CAP) recently it has been introduced as an innovative therapeutic approach for cancer cell treatm...
NSUN2 contributes to the RB malignant progression and Glycolysis by mediating the m5C methylation modification of HKDC1
NSUN2 contributes to the RB malignant progression and Glycolysis by mediating the m5C methylation modification of HKDC1
Retinoblastoma (RB) is a malignant neoplasm originating from photoreceptor precursor cells that is common in children unde...
Mollugin attenuates oxygen-glucose deprivation/reperfusion-induced brain microvascular endothelial cell death and permeability through activation of BDNF/TrkB-modulated Akt pathway
Mollugin attenuates oxygen-glucose deprivation/reperfusion-induced brain microvascular endothelial cell death and permeability through activation of BDNF/TrkB-modulated Akt pathway
Brain microvascular endothelial cell injury is an important pathological basis for blood-brain barrier damage in ischemic ...
TKT regulates the pentose phosphate pathway via RBKS to promote epithelial-mesenchymal transition during AML progression
TKT regulates the pentose phosphate pathway via RBKS to promote epithelial-mesenchymal transition during AML progression
Acute myeloid leukemia is a life-threaten disease. Researches have indicated that increased expression of TKT was closely ...
Dimethyl fumarate improves sepsis-induced acute lung injury by inhibiting STING-mediated ferroptosis
Dimethyl fumarate improves sepsis-induced acute lung injury by inhibiting STING-mediated ferroptosis
The precise pathogenic mechanisms underlying sepsis-induced acute respiratory distress syndrome (ARDS) remain incompletely...
WTAP Silencing protects human aortic smooth muscle cells from angiotensin II-induced senescence, apoptosis, ferroptosis, and inflammation by regulating PCSK9
WTAP Silencing protects human aortic smooth muscle cells from angiotensin II-induced senescence, apoptosis, ferroptosis, and inflammation by regulating PCSK9
Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease characterized by aortic wall degeneration and infla...
E2F7 transcriptionally upregulates SPC24 to mediate aerobic Glycolysis and facilitate stemness of breast cancer
E2F7 transcriptionally upregulates SPC24 to mediate aerobic Glycolysis and facilitate stemness of breast cancer
Metabolic reprogramming characterized by aerobic glycolysis is observed in various cancers, including breast cancer (BC), ...
Early cardioprotective effects of SGLT2i on hypertensive cardiac remodeling via STIM1/Orai1-dependent calcium signaling: beyond blood pressure control
Early cardioprotective effects of SGLT2i on hypertensive cardiac remodeling via STIM1/Orai1-dependent calcium signaling: beyond blood pressure control
The cardioprotective effects of sodium-glucose cotransporter-2 inhibitors (SGLT2i) have attracted significant attention. T...
Untargeted metabolomic analysis of the therapeutic effects of in H22 hepatocellular carcinoma tumor-bearing mice
Untargeted metabolomic analysis of the therapeutic effects of in H22 hepatocellular carcinoma tumor-bearing mice
Pholiota adiposa is a traditional Chinese medicine “Huangsan”. Huangsan is rich in proteins, polysaccharides, ...
The mitochondrial uncoupling proteins in early-branching animals: comparative analysis and transcriptional response to temperature in the jellyfish sp.2
The mitochondrial uncoupling proteins in early-branching animals: comparative analysis and transcriptional response to temperature in the jellyfish sp.2
Uncoupling proteins (UCPs) are mitochondrial membrane proteins involved in metabolite transportation and proton translocat...
The vascular influence of melatonin on endothelial response to angiotensin II in diabetic rat aorta
The vascular influence of melatonin on endothelial response to angiotensin II in diabetic rat aorta
The current study explored melatonin (MEL) and its receptors, including MEL type 1 receptor (MT1) receptor and MEL type 2 ...
Reduction in mitochondrial ATP synthesis mimics the effect of low glucose in depolarizing neurons from the subpostremal nucleus of the solitary tract of rats
Reduction in mitochondrial ATP synthesis mimics the effect of low glucose in depolarizing neurons from the subpostremal nucleus of the solitary tract of rats
Neurons of the subpostremal nucleus of the solitary tract (NTS) respond to changes in extracellular glucose with alteratio...
DSC and FTIR study on the interaction between pentacyclic triterpenoid lupeol and DPPC membrane
DSC and FTIR study on the interaction between pentacyclic triterpenoid lupeol and DPPC membrane
Natural products are a great resource for physiologically active substances. It is widely recognized that a major percenta...
WTAP promotes fibroblast-like synoviocyte pyroptosis in Rheumatoid arthritis by upregulating N6-methyladenosine modification of NLRP3
WTAP promotes fibroblast-like synoviocyte pyroptosis in Rheumatoid arthritis by upregulating N6-methyladenosine modification of NLRP3
Rheumatoid arthritis (RA) is a chronic condition characterized by inflammation and an abnormal immune response. N6-methyla...
NFS1 inhibits ferroptosis in gastric cancer by regulating the STAT3 pathway
NFS1 inhibits ferroptosis in gastric cancer by regulating the STAT3 pathway
Cysteine desulfurase (NFS1) is highly expressed in a variety of tumors, which is closely related to ferroptosis of tumor c...
The effect of intra spinal administration of cerium oxide nanoparticles on central pain mechanism: An experimental study
The effect of intra spinal administration of cerium oxide nanoparticles on central pain mechanism: An experimental study
This study investigated Cerium oxide nanoparticles (CeONPs) effect on central neuropathic pain (CNP). The compressive meth...
CircRNA Arf3 suppresses glomerular mesangial cell proliferation and fibrosis in diabetic nephropathy via miR-107-3p/Tmbim6 axis
CircRNA Arf3 suppresses glomerular mesangial cell proliferation and fibrosis in diabetic nephropathy via miR-107-3p/Tmbim6 axis
Diabetic nephropathy (DN) is one of microvascular complication associated with diabetes. Circular RNAs (circRNAs) have bee...
METTL14 inhibits Aβ1-42-induced neuronal injury through regulating the stability of CBLN4 mRNA in Alzheimer’s disease
METTL14 inhibits Aβ1-42-induced neuronal injury through regulating the stability of CBLN4 mRNA in Alzheimer’s disease
Previous studies have suggested that N6-methyladenosine (mA) modification of RNA affects fundamental aspects of RNA metabo...
Effects of MMP2 and its inhibitor TIMP2 on DNA damage, apoptosis and senescence of human lens epithelial cells induced by oxidative stress
Effects of MMP2 and its inhibitor TIMP2 on DNA damage, apoptosis and senescence of human lens epithelial cells induced by oxidative stress
Oxidative stress-induced lens epithelial cells (LECs) death plays a pivotal role in pathogenesis of age-related cataract (...
N6-methyladenosine (m6A) reader HNRNPA2B1 accelerates the cervical cancer cells aerobic glycolysis
N6-methyladenosine (m6A) reader HNRNPA2B1 accelerates the cervical cancer cells aerobic glycolysis
N6-methyladenosine (m6A) modification is, a more common epigenetic modification, mainly found in mRNA. More and more resea...
LncRNA UCA1 enhances NRF2 expression through the m6A pathway to mitigate oxidative stress and ferroptosis in aging cardiomyocytes
LncRNA UCA1 enhances NRF2 expression through the m6A pathway to mitigate oxidative stress and ferroptosis in aging cardiomyocytes
To explore the regulatory mechanism of lncRNA UCA1 and NRF2 in cardiomyocyte aging. In this study, we explored how lncRNA ...
Load More
format_indent_increase