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Genetic and pharmacological targeting of mTORC1 in mouse models of arteriovenous malformation expose non-cell autonomous signalling in HHT
Genetic and pharmacological targeting of mTORC1 in mouse models of arteriovenous malformation expose non-cell autonomous signalling in HHT
Arteriovenous malformations (AVMs) are abnormal high flow shunts between arteries and veins with major negative impact on ...
Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
Neuropilin-1 (NRP1) regulates endothelial cell (EC) biology through modulation of vascular endothelial growth factor recep...
Effect of oral nintedanib vs placebo on epistaxis in hereditary hemorrhagic telangiectasia: the EPICURE multicenter randomized double-blind trial
Effect of oral nintedanib vs placebo on epistaxis in hereditary hemorrhagic telangiectasia: the EPICURE multicenter randomized double-blind trial
Epistaxis greatly affects patients with hereditary hemorrhagic telangiectasia (HHT). Although few systemic treatment exist...
Anti-angiogenic therapy as potential treatment for adenomyosis
Anti-angiogenic therapy as potential treatment for adenomyosis
Adenomyosis is characterized by abnormal uterine bleeding, dysmenorrhea and subfertility. Increased expression of angiogen...
The role of liver sinusoidal endothelial cells in metabolic dysfunction-associated steatotic liver diseases and liver cancer: mechanisms and potential therapies
The role of liver sinusoidal endothelial cells in metabolic dysfunction-associated steatotic liver diseases and liver cancer: mechanisms and potential therapies
Liver sinusoidal endothelial cells (LSECs), with their unique morphology and function, have garnered increasing attention ...
From bench to bedside: murine models of inherited and sporadic brain arteriovenous malformations
From bench to bedside: murine models of inherited and sporadic brain arteriovenous malformations
Brain arteriovenous malformations are abnormal vascular structures in which an artery shunts high pressure blood directly ...
Clioquinol inhibits angiogenesis by promoting VEGFR2 degradation and synergizes with AKT inhibition to suppress triple-negative breast cancer vascularization
Clioquinol inhibits angiogenesis by promoting VEGFR2 degradation and synergizes with AKT inhibition to suppress triple-negative breast cancer vascularization
Inhibition of angiogenesis, either as monotherapy or in conjunction with other treatments, holds significant promise in ca...
Correction: Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
Correction: Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Cxcl9 modulates aging associated microvascular metabolic and angiogenic dysfunctions in subcutaneous adipose tissue
Cxcl9 modulates aging associated microvascular metabolic and angiogenic dysfunctions in subcutaneous adipose tissue
Microvascular aging, predominantly driven by endothelial cells (ECs) dysfunction, is a critical early event in cardiovascu...
Correction: CCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation
Correction: CCL4 contributes to aging related angiogenic insufficiency through activating oxidative stress and endothelial inflammation
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Isolated human adipose microvessels retain native microvessel structure and recapitulate sprouting angiogenesis
Isolated human adipose microvessels retain native microvessel structure and recapitulate sprouting angiogenesis
With interest growing in modeling more complex aspects of human disease in the laboratory, the need for effectively vascul...
Immune-privileged cord blood-derived endothelial colony-forming cells: advancing immunomodulation and vascular regeneration
Immune-privileged cord blood-derived endothelial colony-forming cells: advancing immunomodulation and vascular regeneration
Cord blood-derived endothelial colony-forming cells (CB-ECFCs) hold significant promise for regenerative medicine due to t...
Microvascular and cerebrovascular alterations in Raynaud’s phenomenon and fibromyalgia
Microvascular and cerebrovascular alterations in Raynaud’s phenomenon and fibromyalgia
Consent for publication Written informed consent was obtain...
Endothelial USP11 drives VEGFR2 signaling and angiogenesis via PRDX2/c-MYC axis
Endothelial USP11 drives VEGFR2 signaling and angiogenesis via PRDX2/c-MYC axis
Angiogenesis is a crucial component of various physiological and pathological processes, including embryonic development, ...
ApoM-bound S1P acts via endothelial S1PR1 to suppress choroidal neovascularization and vascular leakage
ApoM-bound S1P acts via endothelial S1PR1 to suppress choroidal neovascularization and vascular leakage
Neovascular age-related macular degeneration (nAMD) is a major cause of vision loss worldwide. Current standard of care is...
Sex and resting heart rate influence the relation between arterial stiffness and cardiac structure and function – insights from the general population
Sex and resting heart rate influence the relation between arterial stiffness and cardiac structure and function – insights from the general population
Arterial stiffness, a risk factor for cardiovascular disease, can be measured using pulse wave velocity (PWV) and augmenta...
Relationship between epicardial adipose tissue thickness and sedentary time, physical activity level, and physical performance in patients with hypertension
Epicardial adipose tissue is associated with the development of cardiovascular disease and its increase is positively corr...
Body mass index modifies genetic susceptibility to high systolic blood pressure in adolescents and young adults: results from an 18-year longitudinal study
Body mass index modifies genetic susceptibility to high systolic blood pressure in adolescents and young adults: results from an 18-year longitudinal study
Genome-wide association studies (GWAS) in adults have identified single nucleotide polymorphisms (SNPs) associated with sy...
Home versus routine dialysis-unit blood pressure recordings among patients on hemodialysis
Home versus routine dialysis-unit blood pressure recordings among patients on hemodialysis
The optimal method for the diagnosis of hypertension among patients on hemodialysis remains a controversial issue. Using 4...
PERSPECTIVE – The Growing Global Benefits of Limiting Salt Intake: an urgent call from the World Hypertension League for more effective policy and public health initiatives
PERSPECTIVE – The Growing Global Benefits of Limiting Salt Intake: an urgent call from the World Hypertension League for more effective policy and public health initiatives
Intersalt Cooperative Research Group. Intersalt: an International Study of Electrolyte Excretion And Blood Pressure. Resul...
Population-based surveillance for hypertension awareness, treatment, and control in nine districts - India Hypertension Control Initiative, 2018–19
Population-based surveillance for hypertension awareness, treatment, and control in nine districts - India Hypertension Control Initiative, 2018–19
Hypertension control is the crucial indicator for cardiovascular disease programs. We conducted a baseline cross-sectional...
Correlation between different types of obesity and hypertension in perimenopausal working women
Hypertension (HTN) can lead to a series of target organ damage and is associated with increased cardiovascular disease inc...
Hypertension and Cardiovascular Outcomes in Inflammatory and Autoimmune Diseases: A Systematic Review and Meta-analysis
Hypertension and Cardiovascular Outcomes in Inflammatory and Autoimmune Diseases: A Systematic Review and Meta-analysis
This review aimed to investigate the prevalence of hypertension and cardiovascular (CV) complications in various inflammat...
Beneficial Effects of Exercise on Hypertension-Induced Cardiac Hypertrophy in Adolescents and Young Adults
Beneficial Effects of Exercise on Hypertension-Induced Cardiac Hypertrophy in Adolescents and Young Adults
Hypertension-induced cardiac hypertrophy is widely known as a major risk factor for increased cardiovascular morbidity and...
Is There a Role for SGLT2 Inhibitors in Patients with End-Stage Kidney Disease?
Is There a Role for SGLT2 Inhibitors in Patients with End-Stage Kidney Disease?
Chronic kidney disease and end-stage kidney disease (ESKD) are well-established risk factors for cardiovascular disease (C...
Advances on the Experimental Research in Resistant Hypertension
Advances on the Experimental Research in Resistant Hypertension
Resistant Hypertension (RH) poses a significant public health challenge, contributing to increased mortality, cardiovascul...
Importance of the (Pro)renin Receptor in Activating the Renin-Angiotensin System During Normotensive and Preeclamptic Pregnancies
Importance of the (Pro)renin Receptor in Activating the Renin-Angiotensin System During Normotensive and Preeclamptic Pregnancies
For a healthy pregnancy to occur, a controlled interplay between the maternal circulating renin–angiotensin–al...
Insights into Uromodulin and Blood Pressure
Insights into Uromodulin and Blood Pressure
We review the role of uromodulin, a protein exclusively expressed in the kidney, in blood pressure regulation and hyperten...
Intradialytic Hypertension in Maintenance Hemodialysis
Intradialytic Hypertension in Maintenance Hemodialysis
To summarize the current evidence regarding epidemiology, clinical pathophysiology, and latest therapeutic approaches for ...
Targeting the Brain Leptin-Melanocortin Pathway to Treat Heart Failure
Targeting the Brain Leptin-Melanocortin Pathway to Treat Heart Failure
The role of leptin in regulating cardiac function is still controversial with conflicting results in clinical and preclini...
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