Peripheral Arterial Disease in Human Immunodeficiency Virus Infection

Peach G, Griffin M, Jones KG, Thompson MM, Hinchliffe RJ. Diagnosis and management of peripheral arterial disease. BMJ. 2012;345:e5208. https://doi.org/10.1136/bmj.e5208.

Article  CAS  PubMed  Google Scholar 

Campia U, Gerhard-Herman M, Piazza G, Goldhaber SZ. Peripheral Artery Disease: Past, Present, and Future. Am J Med. 2019;132(10):1133–41. https://doi.org/10.1016/j.amjmed.2019.04.043.

Article  PubMed  Google Scholar 

Kohn CG, Alberts MJ, Peacock WF, Bunz TJ, Coleman CI. Cost and inpatient burden of peripheral artery disease: Findings from the National Inpatient Sample. Atherosclerosis. 2019;286:142–6. https://doi.org/10.1016/j.atherosclerosis.2019.05.026.

Article  CAS  PubMed  Google Scholar 

Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FG, et al. Inter-Society consensus for the management of peripheral arterial disease (TASC II). Eur J Vasc Endovasc Surg. 2007;33(1):S1-75. https://doi.org/10.1016/j.ejvs.2006.09.024.

Article  PubMed  Google Scholar 

Poredos P, Stanek A, Catalano M, Boc V. Ankle-brachial index: diagnostic tool of peripheral arterial disease and predictor of cardiovascular risk-an update of current knowledge. Angiology. 2024;33197241226512. https://doi.org/10.1177/00033197241226512.

Article  CAS  Google Scholar 

Johnston LE, Stewart BT, Yangni-Angate H, Veller M, Upchurch GR Jr., Gyedu A, et al. Peripheral arterial disease in sub-Saharan Africa: a review. JAMA Surg. 2016;151(6):564–72. https://doi.org/10.1001/jamasurg.2016.0446.

Article  PubMed  PubMed Central  Google Scholar 

Hackler EL 3, Hamburg NM, White Solaru KT. Racial and ethnic disparities in peripheral artery disease. Circ Res. 2021;128:1913–26. https://doi.org/10.1161/CIRCRESAHA.121.318243.

Article  CAS  PubMed  Google Scholar 

Gornik HL, Aronow HD, Goodney PP, Arya S, Brewster LP, Byrd L, et al. 2024 ACC/AHA/AACVPR/APMA/ABC/SCAI/SVM/SVN/SVS/SIR/VESS Guideline for the Management of Lower Extremity Peripheral Artery Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2024;149(24):e1313-e410. https://doi.org/10.1161/CIR.0000000000001251.

Article  Google Scholar 

Mumtaz A, Tariq Berlas MF, Malik J, Bhojani MF, Moeed A, Panhwar W, et al. Comparison of bypass surgery versus endovascular interventions for peripheral artery disease through systematic review and meta-analysis of randomized controlled trials. J Vasc Interv Radiol. 2025. https://doi.org/10.1016/j.jvir.2025.02.005.

Article  PubMed  Google Scholar 

Naidoo N, Pillay B, Le Roux D. Vascular Society of southern Africa (VASSA) 2020 clinical practice guidelines on the management of peripheral arterial disease. S Afr Med J. 2022;112(2b):126–84.

Google Scholar 

Mayne ES, Louw S. Good Fences Make Good Neighbors: Human Immunodeficiency Virus and Vascular Disease. Open Forum Infect Dis. 2019;6(11):ofz303. https://doi.org/10.1093/ofid/ofz303.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Neuhaus J, Angus B, Kowalska JD, La Rosa A, Sampson J, Wentworth D, et al. Risk of all-cause mortality associated with nonfatal AIDS and serious non-AIDS events among adults infected with HIV. AIDS. 2010;24(5):697–706. https://doi.org/10.1097/QAD.0b013e3283365356.

Article  PubMed  PubMed Central  Google Scholar 

Mayne ES, George JA. Mortal allies: human immunodeficiency virus and noncommunicable diseases. Curr Opin HIV AIDS. 2017;12(2):148–56. https://doi.org/10.1097/COH.0000000000000342.

Article  PubMed  Google Scholar 

Louw S, Mayne ES, Jacobson BF, Mayne AL. Selected inflammatory and coagulation biomarkers pre-viral suppression in people with human immunodeficiency virus (HIV) infection without overt cardiovascular disease: is there a need to redefine reference indices? Cytokine. 2023;165:156174. https://doi.org/10.1016/j.cyto.2023.156174.

Article  CAS  PubMed  Google Scholar 

Agrati C, Mazzotta V, Pinnetti C, Biava G, Bibas M. Venous thromboembolism in people living with HIV infection (PWH). Transl Res. 2020. https://doi.org/10.1016/j.trsl.2020.07.007.

Article  PubMed  Google Scholar 

Louw S, Gededzha MP, Mayne AL, Mayne ES. Thrombotic thrombocytopenic purpura in HIV-infected patients: new twists on an old disease. AIDS. 2022;36(10):1345–54. https://doi.org/10.1097/QAD.0000000000003257.

Article  CAS  PubMed  Google Scholar 

Louw S, Gounden R, Mayne ES. Thrombotic thrombocytopenic purpura (TTP)-like syndrome in the HIV era. Thromb J. 2018;16:35. https://doi.org/10.1186/s12959-018-0189-x.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Louw S, Jacobson BF, Mayne ES. Distinguishing and overlapping laboratory results of thrombotic microangiopathies in HIV infection: can scoring systems assist? J Clin Apher. 2022;37(5):460–7. https://doi.org/10.1002/jca.22003.

Article  PubMed  PubMed Central  Google Scholar 

Mayne ES, Mayne A, Louw S. Diagnosis of human immunodeficiency virus associated disseminated intravascular coagulation. PLoS One. 2022;17(1):e0262306. https://doi.org/10.1371/journal.pone.0262306.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Funderburg NT, Andrade A, Chan ES, Rosenkranz SL, Lu D, Clagett B, et al. Dynamics of immune reconstitution and activation markers in HIV+ treatment-naive patients treated with raltegravir, tenofovir disoproxil fumarate and emtricitabine. PLoS One. 2013;8(12):e83514. https://doi.org/10.1371/journal.pone.0083514.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hileman CO, Funderburg NT. Inflammation, immune activation, and antiretroviral therapy in HIV. Curr HIV AIDS Rep. 2017;14(3):93–100. https://doi.org/10.1007/s11904-017-0356-x.

Article  PubMed  PubMed Central  Google Scholar 

Botes K, Van Marle J. Surgical intervention for HIV related vascular disease. Eur J Vasc Endovasc Surg. 2007;34(4):390–6. https://doi.org/10.1016/j.ejvs.2007.06.007.

Article  CAS  PubMed  Google Scholar 

van Marle J, Mistry PP, Botes K. HIV-occlusive vascular disease. S Afr J Surg. 2009;47(2):36–42.

PubMed  Google Scholar 

van Marle J, Tudhope L, Weir G, Botes K. Vascular disease in HIV/AIDS patients. S Afr Med J. 2002;92(12):974–8.

PubMed  Google Scholar 

Sharma A, Holman S, Pitts R, Minkoff HL, Dehovitz JA, Lazar J. Peripheral arterial disease in HIV-infected and uninfected women. HIV Med. 2007;8(8):555–60. https://doi.org/10.1111/j.1468-1293.2007.00509.x.

Article  CAS  PubMed  Google Scholar 

Bernal E, Masia M, Padilla S, Hernandez I, Gutierrez F. Low prevalence of peripheral arterial disease in HIV-infected patients with multiple cardiovascular risk factors. J Acquir Immune Defic Syndr. 2008;47(1):126–7. https://doi.org/10.1097/QAI.0b013e318157b0b3.

Article  PubMed  Google Scholar 

Palacios R, Alonso I, Hidalgo A, Aguilar I, Sanchez MA, Valdivielso P et al. Peripheral arterial disease in HIV patients older than 50 years of age. AIDS Res Hum Retroviruses. 2008;24(8):1043 – 6. https://doi.org/10.1089/aid.2008.0001

Periard D, Cavassini M, Taffe P, Chevalley M, Senn L, Chapuis-Taillard C, et al. High prevalence of peripheral arterial disease in HIV-infected persons. Clin Infect Dis. 2008;46(5):761–7. https://doi.org/10.1086/527564.

Article  PubMed  Google Scholar 

Johns K, Saeedi R, Mancini GB, Bondy G. Ankle brachial index screening for occult vascular disease is not useful in HIV-positive patients. AIDS Res Hum Retroviruses. 2010;26(9):955–9. https://doi.org/10.1089/aid.2009.0275.

Article  PubMed  Google Scholar 

Jang JJ, Schwarcz AI, Amaez DA, Woodward M, Olin JW, Keller MJ et al. Elevated osteoprotegerin is associated with abnormal ankle brachial indices in patients infected with HIV: a cross-sectional study. J Int AIDS Soc. 2010;13:12. https://doi.org/10.1186/1758-2652-13-12

Choi AI, Li Y, Deeks SG, Grunfeld C, Volberding PA, Shlipak MG. Association between kidney function and albuminuria with cardiovascular events in HIV-infected persons. Circulation. 2010;121(5):651 – 8. https://doi.org/10.1161/CIRCULATIONAHA.109.898585

Ye Y, Zeng Y, Li X, Zhang S, Fang Q, Luo L, et al. HIV infection: an independent risk factor of peripheral arterial disease. J Acquir Immune Defic Syndr. 2010;53(2):276–8. https://doi.org/10.1097/QAI.0b013e3181ba1c31.

Article  PubMed 

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