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The Structural and Functional Journey of Apolipoprotein A-I Through the Human Body
The Structural and Functional Journey of Apolipoprotein A-I Through the Human Body
Apolipoprotein A-I (APOA1) is the primary protein and structural scaffold on high density lipoproteins (HDL), playing key ...
Peripheral Arterial Disease in Human Immunodeficiency Virus Infection
Peripheral Arterial Disease in Human Immunodeficiency Virus Infection
Human immunodeficiency virus infection (HIV) is a chronic inflammatory and pro-atherosclerotic condition although the cont...
High Density Lipoprotein Assessment Revisited: A Review of Foundational Understanding and Recent Developments in Function, Particle Size, and Cardiometabolic Impact
High Density Lipoprotein Assessment Revisited: A Review of Foundational Understanding and Recent Developments in Function, Particle Size, and Cardiometabolic Impact
High density lipoprotein (HDL) has historically been considered cardioprotective, with HDL cholesterol (HDL-C) levels wide...
Depression, Anxiety, and Bipolar Disorder and Atherosclerosis
Depression, Anxiety, and Bipolar Disorder and Atherosclerosis
This review describes the complex relationships between depression, anxiety, and bipolar disorder with atherosclerosis by ...
CETP Renaissance with Obicetrapib
CETP Renaissance with Obicetrapib
This review examines the emerging role of cholesteryl ester transfer protein (CETP) inhibition, with a focus on obicetrapi...
Regulation of Cholesterol and Triglyceride Metabolism by Fatty acid Ethanolamides
Regulation of Cholesterol and Triglyceride Metabolism by Fatty acid Ethanolamides
This paper reviews the existing literature supporting a role for fatty acid ethanolamides including oleoylethanolamide and...
Neuroimmune Dynamics in Diseases of the Arterial Wall: Mechanistic Foundations and Translational Prospects
Neuroimmune Dynamics in Diseases of the Arterial Wall: Mechanistic Foundations and Translational Prospects
Peripheral nerves are increasingly recognized as regulators of vascular pathology, shaping arterial tone, inflammation, an...
Spontaneous Coronary Artery Dissection: Advances in Understanding and Management in Women
Spontaneous Coronary Artery Dissection: Advances in Understanding and Management in Women
Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute myocardial infarction (MI), par...
Metabolic Pathways Linking Atherosclerotic Cardiovascular Disease With Metabolic Dysfunction-Associated Steatotic Liver Disease
Metabolic Pathways Linking Atherosclerotic Cardiovascular Disease With Metabolic Dysfunction-Associated Steatotic Liver Disease
This review explores the metabolic pathways dysregulated in both atherosclerotic cardiovascular disease (ASCVD) and metabo...
Unraveling Atherosclerosis through Multi-omics: Systematic Insights into the Unique Applications and Clinical Perspectives
Unraveling Atherosclerosis through Multi-omics: Systematic Insights into the Unique Applications and Clinical Perspectives
Atherosclerosis (AS) is a progressive disease of the arterial wall characterized by metabolic dysregulation, inflammatory ...
Gut Microbial Dysbiosis in Type 2 Diabetes Patients with Concurrent Atherosclerosis
Gut Microbial Dysbiosis in Type 2 Diabetes Patients with Concurrent Atherosclerosis
The association of the gut microbiome with T2DM has been conflicting due to the disease’s inherent complexity—...
Incidental Detection of Coronary Artery Calcification in Women Undergoing Cancer Screening or Treatment
Incidental Detection of Coronary Artery Calcification in Women Undergoing Cancer Screening or Treatment
Cardiovascular disease and cancer are significant causes of morbidity and mortality. Cancer screening in woman provides an...
Pharmacogenomics of Atherosclerotic Plaque: Pathophysiological Background and Therapeutic Perspectives
Pharmacogenomics of Atherosclerotic Plaque: Pathophysiological Background and Therapeutic Perspectives
Advances in pharmacogenomics have paved the way for personalized medicine. Cardiovascular diseases still represent the lea...
Microcalcification: Effects on Atherosclerotic Vulnerable Plaques, Detection, and Therapeutic Perspectives
Microcalcification: Effects on Atherosclerotic Vulnerable Plaques, Detection, and Therapeutic Perspectives
We aim to elucidate the formation mechanisms of microcalcification in atherosclerotic plaques, systematically clarify its ...
Desialylated vs. Oxidized LDL: Sialidase Inhibitors as Promising Antiatherosclerotic Agents
Desialylated vs. Oxidized LDL: Sialidase Inhibitors as Promising Antiatherosclerotic Agents
The accumulation of lipids, particularly cholesteryl esters, in the arterial intima is an early sign of atherogenesis. Alt...
Beyond the Coronaries: Utility of Extra-Coronary Calcification for Cardiovascular Risk Assessment in Women
Beyond the Coronaries: Utility of Extra-Coronary Calcification for Cardiovascular Risk Assessment in Women
Globally, cardiovascular disease (CVD) is the leading cause of mortality in women. Traditional risk calculators underestim...
Patient Engagement Strategies for Implementing Evidence-Based Care in Atherosclerosis
Patient Engagement Strategies for Implementing Evidence-Based Care in Atherosclerosis
Despite continuing therapeutic advances in cardiovascular disease, it remains a leading cause of morbidity and mortality i...
Anti-Atherogenic Mechanisms and Therapies
Anti-Atherogenic Mechanisms and Therapies
This review examines anti-atherogenic mechanisms and the crucial role of efferocytosis in promoting inflammation resolutio...
Salutary Effects of Nutritional Ketosis for the Diseased Human Heart
Salutary Effects of Nutritional Ketosis for the Diseased Human Heart
We provide an overview of cardiac metabolism, ketone physiology and terminology, methods of elevating ketones and their ef...
Transforming Population Health Screening for Atherosclerotic Cardiovascular Disease with AI-Enhanced ECG Analytics: Opportunities and Challenges
Transforming Population Health Screening for Atherosclerotic Cardiovascular Disease with AI-Enhanced ECG Analytics: Opportunities and Challenges
To define the emerging role of artificial intelligence-enhanced electrocardiography (AI-ECG) in advancing population-level...
The Bidirectionality of Psychosocial Stress and Cardiovascular Disease Risk in Women; Recognition and Strategies for Management
The Bidirectionality of Psychosocial Stress and Cardiovascular Disease Risk in Women; Recognition and Strategies for Management
This review describes and summarizes the relationships between psychosocial stress and cardiovascular disease risk in wome...
Cardiovascular Risk Prediction in Older Adults
Cardiovascular Risk Prediction in Older Adults
This review examines cardiovascular disease (CVD) risk prediction models relevant to older adults, a rapidly expanding pop...
Unveiling the Sex-Based Divide: Exploring Sex Differences in Peripheral Artery Disease
Unveiling the Sex-Based Divide: Exploring Sex Differences in Peripheral Artery Disease
Peripheral artery disease (PAD) is a leading cause of cardiovascular morbidity and mortality. Despite its growing clinical...
Dietary Management of Atherogenic Dyslipidemia
Dietary Management of Atherogenic Dyslipidemia
This paper reviews the effects of major macronutrients and specific dietary interventions on atherogenic dyslipidemia, a c...
Tackling the Cardio-Kidney-Metabolic Burden in Cancer
Tackling the Cardio-Kidney-Metabolic Burden in Cancer
This review aims to examine the clinical relevance of cardio-kidney-metabolic syndrome (CKMS) in oncology, highlighting it...
Effects of Pioglitazone On Lipoprotein(a): A Meta-analysis
Effects of Pioglitazone On Lipoprotein(a): A Meta-analysis
To evaluate the effect of pioglitazone, a member of the thiazolidinedione family of drugs known for its antihyperglycemic ...
Correlation Between Oral Bacteria and Atherosclerotic Thrombotic Disease: Advances in Animal Model Studies
Correlation Between Oral Bacteria and Atherosclerotic Thrombotic Disease: Advances in Animal Model Studies
This review summarizes the current applications of animal models in studying oral bacteria and atherosclerotic thrombotic ...
Self-DNA by Activating the CGAS-STING1 Pathway Contributes to the Pathogenesis of Atherosclerosis
Self-DNA by Activating the CGAS-STING1 Pathway Contributes to the Pathogenesis of Atherosclerosis
To discuss the role of self-DNA in activating the cytosolic DNA-sensing proteins (CDSPs) and inducing low-grade inflammati...
Serial Coronary CTA for Monitoring Response to Lipid-Lowering Therapy: A Narrative Review
Serial Coronary CTA for Monitoring Response to Lipid-Lowering Therapy: A Narrative Review
This review summarizes current evidence on the use of serial coronary computed tomography angiography (CCTA) to monitor th...
AI in Adipose Imaging: Revolutionizing Visceral Adipose Tissue, Ectopic Fat, and Cardiovascular Risk Assessment
AI in Adipose Imaging: Revolutionizing Visceral Adipose Tissue, Ectopic Fat, and Cardiovascular Risk Assessment
This review explores the role of artificial intelligence (AI) in visceral adipose tissue (VAT) and ectopic fat imaging. It...
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