SCI Abstract

search
Purinosomes as a therapeutic target in hepatocellular carcinoma: insights and opportunities
Purinosomes as a therapeutic target in hepatocellular carcinoma: insights and opportunities
The formation of purinosomes, dynamic complexes involved in de novo purine biosynthesis, has been recognized as a critical...
CXCR7 promoted proliferation, migration and invasion in HCC Cells by inactivating Hippo-YAP signaling
CXCR7 promoted proliferation, migration and invasion in HCC Cells by inactivating Hippo-YAP signaling
CXCR7 (ACKR3) has been well-supported as a promoter of growth and metastasis in hepatocellular carcinoma (HCC). Both CXCR7...
ZNF280A promotes malignant melanoma development through regulating cell proliferation, apoptosis, and cell cycle
ZNF280A promotes malignant melanoma development through regulating cell proliferation, apoptosis, and cell cycle
Malignant melanoma (MM) is the most lethal skin cancer globally, with a high incidence of over 300,000 per year. Though co...
is an independent predictor for the prognosis of gastric cancer
is an independent predictor for the prognosis of gastric cancer
To explore novel biomarkers capable of predicting the prognosis of gastric cancer (GC) and investigate the mechanisms unde...
Single-cell RNA sequencing reveals key signaling pathways and biological functions in giant cell tumors of bone
Single-cell RNA sequencing reveals key signaling pathways and biological functions in giant cell tumors of bone
Giant cell tumor of bone (GCTB) represents a group of tumors that characterized by their heterogeneity and the presence of...
P4HA1 is highly expressed in gastric cancer and promotes proliferation and metastasis of gastric cancer cells
P4HA1 is highly expressed in gastric cancer and promotes proliferation and metastasis of gastric cancer cells
Gastric cancer (GC), a prevalent aggressive form of tumor, imposes a significant burden in terms of morbidity and mortalit...
Plasma protein levels and hepatocellular carcinoma: a Mendelian randomization study with drug screening implications
Plasma protein levels and hepatocellular carcinoma: a Mendelian randomization study with drug screening implications
Hepatocellular carcinoma (HCC) remains a significant cause of cancer-related mortality, highlighting the need for novel th...
Advances in the roles and molecular mechanisms of exosomal circular RNAs in regulating the pre-metastatic niche of tumors
Advances in the roles and molecular mechanisms of exosomal circular RNAs in regulating the pre-metastatic niche of tumors
Metastasis remains a major cause of morbidity and mortality in patients with malignant tumors. The pre-metastatic niche is...
Prognostic value of combined nutritional and inflammatory markers in NSCLC patients receiving ICIs
Prognostic value of combined nutritional and inflammatory markers in NSCLC patients receiving ICIs
In the treatment of non-small cell lung cancer (NSCLC), immune checkpoint inhibitors (ICIs) have markedly improved patient...
Research progress on ADAM28 in malignant tumors
Research progress on ADAM28 in malignant tumors
A disintegrin and metalloproteinase (ADAM) 28 belongs to the zinc-dependent metalloproteinase superfamily and has a signal...
Glycosphingolipids as emerging attack points in bladder cancer
Glycosphingolipids as emerging attack points in bladder cancer
Bladder cancer is a prevalent malignancy associated with significant morbidity and mortality worldwide. Emerging research ...
Next-generation sequencing in cancer diagnosis and treatment: clinical applications and future directions
Next-generation sequencing in cancer diagnosis and treatment: clinical applications and future directions
Next-generation sequencing (NGS) has emerged as a pivotal technology in the field of oncology, transforming the approach t...
Interactions between long non-coding RNAs and m6 A modification in cancer
Interactions between long non-coding RNAs and m6 A modification in cancer
Long non-coding RNAs (lncRNAs) are a class of transcripts exceeding 200 nucleotides (nt) in length, which are broadly impl...
MTHFD2 marks pemetrexed resistance in pulmonary adenocarcinoma with EGFR wild type
MTHFD2 marks pemetrexed resistance in pulmonary adenocarcinoma with EGFR wild type
Lung cancer is the leading cause of cancer-related deaths worldwide. Patients with an amplification of the MTHFD2 gene hav...
Machine learning-based prognostic modelling of NK cells in PAAD for immunotherapy guidance
Machine learning-based prognostic modelling of NK cells in PAAD for immunotherapy guidance
Pancreatic cancer’s high incidence and mortality rates are underscored by ineffective treatments, particularly immun...