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Neuroprotective effects of hesperidin and auraptene on 6-hydroxydopamine-induced neurodegeneration in SH-SY5Y cells
Objective: Destruction of dopaminergic neurons causes diseases. Various compounds with neuroprotective and antioxidant pro...
The hydroalcoholic extract of Nasturtium officinale protectively inhibits apoptotic and inflammatory pathways in hepato- and nephrotoxicity: An in vivo study
Objective: Nasturtium officinale (N. officinale (NO)) has been widely used in traditional medicine. This study investigate...
Inhibition of mast cell activation via MRGPRX2 receptor by Curcuma mangga and Sonchus arvensis water suspensions: An in vitro study
Objective: Traditional medicine is often used to relief pain, but its use is frequently not supported by appropriate scien...
Phenolic screening, antioxidant activity and diuretic effect of Moroccan Pinus pinaster Bark extract
Objective: This study aims to evaluate the chemical composition antioxidant activity, and diuretic effects of Moroccan Pin...
The effects of an Aloe-based polyherbal formulation on fertility parameters in male rats
Objective: Aloe dry juice as a purgative agent is widely used in phytotherapy. In Iranian traditional medicine to decrease...
The relaxant effect of the extract of Crocus sativus petal on Wistar rats airway smooth muscle and its possible mechanisms
Objective: Obstructive pulmonary diseases are characterized by airflow limitation secondary to airway wall thickening, air...
Effects of royal jelly consumption on inflammation and oxidative stress: A systematic review and meta-analysis of randomized controlled trials
Objective: This systematic review and meta-analysis examines the impact of royal jelly (RJ) on inflammation and oxidative ...
The role of Anvillea garcinii and its compounds in health and disease: An overview
Objective: This scoping review aims to examine the potential health benefits of Anvillea garcinii and its compounds and pr...
Investigating the potential effects of olive leaves and ginger rhizome extracts on kidney and liver functions in alloxan-induced diabetic rats
Objective: Although there are many drugs on the shelves of pharmacies to manage diabetes mellitus (DM), many people around...
Investigating the effect of a herbal cream containing rose essence in an animal model of eczema
Objective: Eczema, a common inflammatory skin condition characterized by itching and dermatitis, can significantly impact ...
The effects of carvacrol on the cardiac apoptosis gene expression levels in heart tissue of obese male rats induced by high-fat diet
Objective: Animal studies have revealed that lipid accumulation in obese mice fed with a high-fat diet (HFD) leads to alte...
Possible effects of royal jelly against neuronal injury in the hippocampus of ovariectomized rats with pentylenetetrazol-induced seizures: Role of luteinizing and follicle-stimulating hormones
Objective: This study aimed to investigate the potential impact of royal jelly (RJ) on hippocampal neurons in an ovariecto...
Anti-leishmanial effect of the hydroalcoholic extract of the leaves, roots and seeds of Arctium lappa
Objective: Zoonotic cutaneous leishmaniasis is a common including endemic infectious disease in many parts of the world an...
Protective role of zeaxanthin on acrylamide-induced neurotoxicity in Wistar rats
Objective: The Maillard reaction generates acrylamide (ACR), a toxic compound commonly found in laboratory and industrial ...
The effect of wet cupping on reactive airway dysfunction syndrome (RADS) caused by early exposure to chlorine gas: A randomized clinical trial
Objective: In the absence of targeted antidotes for chlorine gas poisoning, a common yet concerning problem, this study in...
Effect of Daucus carota L. extract on spermiogram factors in men with idiopathic infertility: A double‐blinded randomized clinical trial
Objective: Male infertility is a common issue that affects people worldwide and presents challenges in terms of treatment....
Protective effects of Indigofera argentea against acetic acid-induced inflammatory bowel disease are mediated by modulating antioxidant and inflammatory mediators
Objective: The plant Indigofera argentea Burm. f., belonging to the family Fabaceae, is locally known as Hathio, Jantar an...
Antimicrobial effectiveness of aqueous and alcoholic herbal extracts on Streptococcus mutans: A systematic review and meta-analysis of randomized controlled trials
Objective: Debates about the efficacy of herbal products in oral care have inspired researchers to conduct a large number ...
Exploring the anti-inflammatory effects of Lavandula stoechas L. extract on ovalbumin-induced acute asthma in BALB/c mice
Objective: Asthma is an inflammatory disease of the respiratory system affecting over 300 million people worldwide. Lavand...
Evaluating the effect of crocin on contrast-induced nephropathy in rats
Objective: Contrast-induced nephropathy (CIN) raises the risk of renal injury, but crocin, a saffron component, may improv...
Discovery of structurally diverse sesquiterpenoids from isolated from feces and their antifungal activities
Discovery of structurally diverse sesquiterpenoids from isolated from feces and their antifungal activities
Thirty-six structurally diverse sesquiterpenoids, including caryolanes (1–12), germacranes (13–16), isodaucane...
Diterpene chemical space of Briq. aerial part
Diterpene chemical space of Briq. aerial part
The Plectranthinae clade, which includes genera such as Plectranthus, Ocimum, and Aeollanthus, is well known for its diver...
Euchrestifolines A–O, fifteen novel carbazole alkaloids with potent anti-ferroptotic activity from
Euchrestifolines A–O, fifteen novel carbazole alkaloids with potent anti-ferroptotic activity from
Fifteen novel carbazole alkaloids, euchrestifolines A–O (1–15), were obtained from Murraya euchrestifolia. The...
Widely targeted metabolomics analysis reveals differences in volatile metabolites among four species
Widely targeted metabolomics analysis reveals differences in volatile metabolites among four species
Angelica L. has attracted global interest for its traditional medicinal uses and commercial values. However, few studies h...
Phytochemical fingerprinting of phytotoxins as a cutting-edge approach for unveiling nature’s secrets in forensic science
Phytochemical fingerprinting of phytotoxins as a cutting-edge approach for unveiling nature’s secrets in forensic science
The integration of phytochemistry into forensic science has emerged as a groundbreaking frontier, providing unprecedented ...
Unveiling the mechanism of action of a novel natural dual inhibitor of SARS-CoV-2 Mpro and PLpro with molecular dynamics simulations
Unveiling the mechanism of action of a novel natural dual inhibitor of SARS-CoV-2 Mpro and PLpro with molecular dynamics simulations
In the twenty-first century, we have witnessed multiple coronavirus pandemics. Despite declining SARS-CoV-2 cases, continu...
New semisynthetic α-glucosidase inhibitor from a doubly-chemically engineered extract
New semisynthetic α-glucosidase inhibitor from a doubly-chemically engineered extract
Chemically engineered extracts represent a promising source of new bioactive semi-synthetic molecules. Prepared through di...
Discovery of a parallel family of euglenatide analogs in
Discovery of a parallel family of euglenatide analogs in
The euglenatides are a family of hybrid polyketide-nonribosomal peptides produced by the unicellular algae Euglena gracili...
Novel -clerodane diterpenoids from and their anti-ferroptosis effect
Novel -clerodane diterpenoids from and their anti-ferroptosis effect
Teucrifarides A–D (1–4), four previously unreported neo-clerodane-type diterpenoids, combined with sixteen kno...
Dibohemamines I–O from sp. GZWMJZ-662, an endophytic actinomycete from the medicinal and edible plant Thunb.
Dibohemamines I–O from sp. GZWMJZ-662, an endophytic actinomycete from the medicinal and edible plant Thunb.
A chemical investigation of Streptomyces sp. GZWMJZ-662, an endophytic actinomycete isolated from Houttuynia cordata Thunb...
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