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Reduced 5-HT receptor responsiveness in rats after chronic midazolam treatment: behavioral and neurochemical evidence in rats
Reduced 5-HT receptor responsiveness in rats after chronic midazolam treatment: behavioral and neurochemical evidence in rats
Repeated administration of midazolam, a benzodiazepine with potent anxiolytic properties, has been associated wit...
Mesenchymal stromal cells from umbilical Wharton’s jelly provide cerebroprotection in acute ischemic stroke: evidence from a rat study
Mesenchymal stromal cells from umbilical Wharton’s jelly provide cerebroprotection in acute ischemic stroke: evidence from a rat study
Mesenchymal stromal cells of human umbilical cord Wharton’s jelly (hWJ-MSCs) show considerable potential in regenera...
Improved skin–nerve preparation technique for recording from cutaneous afferents
Improved skin–nerve preparation technique for recording from cutaneous afferents
The skin–nerve preparation technique, originally developed by Reeh in the late 1980s, remains a unique ex v...
Behavioral phenotypes in Alzheimer’s disease: exploring novel therapeutic targets using animal models and behavioral assays
Behavioral phenotypes in Alzheimer’s disease: exploring novel therapeutic targets using animal models and behavioral assays
The neurodegenerative condition known as Alzheimer’s disease (AD) is characterized by behavioral abnormalities and c...
Schisandrin B Improves Mitochondrial Function and Inhibits HT22 Cell Apoptosis by Regulating Sirt3 Protein
Schisandrin B Improves Mitochondrial Function and Inhibits HT22 Cell Apoptosis by Regulating Sirt3 Protein
Neurological diseases refer to pathological changes that occur in the brain, spinal cord, and peripheral nerves. Their eti...
Single-Molecule Insights into GPCR Conformational Landscapes
Single-Molecule Insights into GPCR Conformational Landscapes
Agyemang E, Gonneville AN, Tiruvadi-Krishnan S, Lamichhane R (2024) Exploring GPCR conformational dynamics using single-mo...
Metabolic Energy is Stored in a Homeostatic Trans-Membrane Water Barochemical Gradient
Metabolic Energy is Stored in a Homeostatic Trans-Membrane Water Barochemical Gradient
Trans-membrane water transport and co-transport is ubiquitous in cell biology. Integrated over all the c...
Correction: Single‑Molecule Insights into GPCR Conformational Landscapes
Correction: Single‑Molecule Insights into GPCR Conformational Landscapes
Share this articleAnyone you share the following link with will be able to read this content:Get shareable linkSorry, a sh...
Action of the Terminal Complement Pathway on Cell Membranes
Action of the Terminal Complement Pathway on Cell Membranes
The complement pathway is one of the most ancient elements of the host's innate response and includes a set of protein...
Cholesterol Concentration in Cell Membranes and its Impact on Receptor–Ligand Interaction: A Computational Study of ATP-Sensitive Potassium Channels and ATP Binding
Cholesterol Concentration in Cell Membranes and its Impact on Receptor–Ligand Interaction: A Computational Study of ATP-Sensitive Potassium Channels and ATP Binding
This work describes a computer study that looks at how different amounts of cholesterol (0%, 25%, and 50%) in cell membran...
Pore Formation by Pore Forming Proteins in Lipid Membranes: Structural Insights Through Cryo-EM
Pore Formation by Pore Forming Proteins in Lipid Membranes: Structural Insights Through Cryo-EM
Many pathogenic bacteria utilize their complicated appalling arsenal, bacterial virulence factors, to attack host cells by...
The Effect of Xenon on the Voltage‒Current Characteristics of Tethered Lipid Bilayers
The Effect of Xenon on the Voltage‒Current Characteristics of Tethered Lipid Bilayers
In this study, we describe the effect of the noble gas, xenon on the electrical properties of tethered lipid bilayer membr...
Role of Ion Channels in Alzheimer’s Disease Pathophysiology
Role of Ion Channels in Alzheimer’s Disease Pathophysiology
Ion channels play an integral role in the normal functioning of the brain. They regulate neuronal electrical properties li...
Cholesterol Affects the Pore Formation and the Membrane–Membrane Interaction Induced by an Antimicrobial Peptide, NK-2, in Phospholipid Vesicles
Cholesterol Affects the Pore Formation and the Membrane–Membrane Interaction Induced by an Antimicrobial Peptide, NK-2, in Phospholipid Vesicles
Antimicrobial peptides are part of the innate immune response and show their antimicrobial activity by forming pores, foll...
Functional and Physiological Implications of Oligopeptide Transporters: Potential Targets for Pharmacological Interventions
Functional and Physiological Implications of Oligopeptide Transporters: Potential Targets for Pharmacological Interventions
Peptide transporters are important plasma membrane proteins that facilitate the cellular uptake of di- and tripeptides in ...
Oxysterols Outcompete Cholesterol Binding to the Membrane-Inserted Cytolysin A Pore Complex
Oxysterols Outcompete Cholesterol Binding to the Membrane-Inserted Cytolysin A Pore Complex
Pore-forming toxins (PFTs) belong to a class of proteins expressed by bacteria to initiate infections by unregulated pore ...
Resurrection of the Helical Hairpin Hypothesis for Understanding Coronavirus Fusion
Resurrection of the Helical Hairpin Hypothesis for Understanding Coronavirus Fusion
Coronaviruses use the spike protein (spike) to bind to target cells, and fuse the viral envelope with a host lipi...
Biomimetic Bacterial Membrane Models for Comprehending Membrane Dynamics
Biomimetic Bacterial Membrane Models for Comprehending Membrane Dynamics
Boucher HW et al (2009) Bad bugs, no drugs: no ESKAPE! An update from the infectious diseases society of America. Clin Inf...
TtfA is a Highly Stable Membrane-Anchored DNA-Binding Protein
TtfA is a Highly Stable Membrane-Anchored DNA-Binding Protein
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a deadly intracellular pathogen, with a per...
Passage of the Channel-Forming Agent Nystatin Through Ergosterol-Containing Lipid Membranes
Passage of the Channel-Forming Agent Nystatin Through Ergosterol-Containing Lipid Membranes
The passage of nystatin through the ergosterol-containing phospholipid bilayer was studied on monovesicular and multivesic...
Stomatin and Stomatin-Like Proteins Can Regulate Transporter Proteins Activity and Has a Role in Cancer Metastasis
Stomatin and Stomatin-Like Proteins Can Regulate Transporter Proteins Activity and Has a Role in Cancer Metastasis
Stomatin, encoded by STOM gene, is an integral membrane protein found in a wide variety of species. Although years have pa...
Molecular Insights into Interactions between Ofloxacin and Ionic Micelles
Molecular Insights into Interactions between Ofloxacin and Ionic Micelles
The growing antimicrobial resistance presents a challenge in developing new potent drugs, but this effort is hindered by a...
Cytokine and adipokine response following high-intensity interval running and cycling in female adolescents
Cytokine and adipokine response following high-intensity interval running and cycling in female adolescents
The purpose of this study was to compare the response of cytokines, and adipokines to high-intensity interval running (HII...
Non-linear heart rate variability is sensitive to exercise duration but not indicative of acute performance decrement
Non-linear heart rate variability is sensitive to exercise duration but not indicative of acute performance decrement
The short-term scaling exponent alpha 1 (DFA α1), derived from detrended fluctuation analysis of heart rate variabili...
Acute sodium bicarbonate supplementation reduces the increase in markers of acute kidney injury during physical work in the heat
Acute sodium bicarbonate supplementation reduces the increase in markers of acute kidney injury during physical work in the heat
In response to metabolic acidosis, compensatory mechanisms are deployed by the kidney to maintain acid–base homeosta...
SERCA blockade as a treatment strategy for obesity
SERCA blockade as a treatment strategy for obesity
Sarco/endoplasmic reticulum calcium ATPase (SERCA) pump is essential for maintaining calcium homeostasis in various cell t...
Brief extreme passive heat exposure leads to elevated biomarkers of systemic inflammation and acute kidney injury in older vs young adults
Brief extreme passive heat exposure leads to elevated biomarkers of systemic inflammation and acute kidney injury in older vs young adults
With the advent of climate change, older adults are increasingly exposed to hot ambient temperatures that can lead to a st...
The influence of high-load and combined high- and low-load resistance training on electromyographic behavior during an absolute muscular endurance task
The influence of high-load and combined high- and low-load resistance training on electromyographic behavior during an absolute muscular endurance task
To compare the effects of 6 weeks of combined high- and low-load lower body resistance training (H + ...
Measured thoracic gas volume using the bod pod air displacement plethysmography system versus three predictions
Measured thoracic gas volume using the bod pod air displacement plethysmography system versus three predictions
Bod Pod air displacement plethysmography is a common method to estimate body fat percentage (%BF). To determine body volum...
How does age affect changes in leg muscle activation patterns and leg joint moments during prolonged walking?
How does age affect changes in leg muscle activation patterns and leg joint moments during prolonged walking?
The ways in which age affects neuromuscular control in response to walking-related fatigue are poorly understood. Better u...
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