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Recent advancements of neoadjuvant strategies in locally advanced rectal cancer
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“Targeting platelets in breast cancer: Insights into pathophysiology and therapeutic strategies”
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Past, present, and future perspectives in estrogen-receptor-low breast cancer
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When defense turns dangerous: The dual nature of senescence in pancreatic ductal adenocarcinoma
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Therapeutic sequencing and role of cabozantinib after immunotherapy in metastatic renal cell carcinoma
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Epidermal growth factor receptor (EGFR) atypical mutations in non-small-cell lung cancer (NSCLC): ‘Where the streets have no name’
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Mapping the immune microenvironment of non-small cell lung cancer
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From G12C To pan-RAS: The expanding therapeutic landscape of KRAS-mutant NSCLC
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Emerging treatment paradigms for gastric cancer peritoneal metastasis in the era of multimodal precision therapy
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Vitamin D receptor in tumors: A review of biological mechanisms, therapeutic potentials, and prognostic values
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Management of atypical cartilaginous tumors (ACT): an Italian Sarcoma Group (ISG) consensus document
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Adjuvant mitotane in low-risk adrenocortical carcinoma: A reconstructed IPD analysis of the ADIUVO randomized and observational studies
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Treatment-related deaths with immune checkpoint inhibitor–based combinations versus tyrosine kinase inhibitor monotherapy in hepatocellular carcinoma: A systematic review and meta-analysis
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When death pathways converge: PANoptosis in the evolution and treatment of female tumors
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Single-cell RNA sequencing unveils CD8+ T cell heterogeneity in the diffuse large B-cell lymphoma microenvironment: A systematic review
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Context-dependent rewiring of the cGAS-STING pathway in cancer: Implications for immunotherapy and therapeutic resistance
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Prognostic impact of CT-defined sarcopenia and prognostic nutritional index in immune checkpoint inhibitor–treated head and neck squamous cell carcinoma: A systematic review and meta-analysis
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The cGAS-STING pathway in the tumor immune microenvironment: Multidimensional regulation and therapeutic implications
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In vivo generation of CAR-T cells: Current obstacles, strategic solutions, and clinical translation
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Immunotherapeutic strategies in HPV-positive and HPV-negative recurrent/metastatic oropharyngeal squamous cell carcinoma: From PD-1 blockade to EGFR-directed bispecifics and therapeutic HPV vaccines
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Emerging Significance and Implications of a Durable Complete Molecular Remission in the Treatment of Polycythemia Vera
Emerging Significance and Implications of a Durable Complete Molecular Remission in the Treatment of Polycythemia Vera
Polycythemia vera (PV) is a Philadelphia chromosome-negative myeloproliferative neoplasm (MPN) caused by a somatic gain-of...
The Role of Inflammation in CMML Pathobiology and Progression
The Role of Inflammation in CMML Pathobiology and Progression
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic malignancy characterized by monocytosis and dysplasia. Wh...
Use of Patient-Reported Outcome Measures in Clinical Studies of Chronic Myeloid Leukemia: A Scoping Literature Review
Use of Patient-Reported Outcome Measures in Clinical Studies of Chronic Myeloid Leukemia: A Scoping Literature Review
Management of chronic myeloid leukemia (CML) with tyrosine kinase inhibitors has improved patient survival. However, patie...
Splicing Factor Mutations in Chronic Myelomonocytic Leukemia: Biological Consequences and Therapeutic Implications
Splicing Factor Mutations in Chronic Myelomonocytic Leukemia: Biological Consequences and Therapeutic Implications
This review will summarize recent research into the diverse biological consequences of splicing factor mutations, and poss...
Myelodysplastic syndromes: Updates on Genomic Landscape, Molecular Subtypes, & Targeted Therapies
Myelodysplastic syndromes: Updates on Genomic Landscape, Molecular Subtypes, & Targeted Therapies
Advances in modern molecular and genomic testing have spurred tremendous progress in our understanding of MDS pathogenesis...
From MRD To Match: the Role of Allogeneic Hematopoietic Cell Transplant in Philadelphia-Negative B-ALL
From MRD To Match: the Role of Allogeneic Hematopoietic Cell Transplant in Philadelphia-Negative B-ALL
Given the high risk of relapse for Philadelphia-negative (Ph-negative) B-cell acute lymphoblastic leukemia (ALL), allogene...
Targeting RUNX1 Germline Variants: Agents Under Investigation
Targeting RUNX1 Germline Variants: Agents Under Investigation
Despite increased recognition of FPDMM and advancements in genetic technologies that have improved carrier identification ...
Impact of Germline DNA Repair Mutations on Clonal Hematopoiesis and Myeloid Neoplasm Development
Impact of Germline DNA Repair Mutations on Clonal Hematopoiesis and Myeloid Neoplasm Development
Clonal hematopoiesis (CH) arises from the expansion of a single hematopoietic stem cell harboring somatic mutations that c...
Understanding Triple Negative Myeloproliferative Neoplasms and Identifying Molecular Drivers
Understanding Triple Negative Myeloproliferative Neoplasms and Identifying Molecular Drivers
Triple-negative (TN) myeloproliferative neoplasms (MPNs), defined by the absence of canonical driver JAK2, CALR and MPL mu...
Advances and Controversies in the Management of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Navigating First-Line Therapies
Advances and Controversies in the Management of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Navigating First-Line Therapies
The goal of this review is to provide an updated synthesis of therapeutic advances and remaining controversies in the mana...
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