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Validation and interpretation of the Triple A model in Turkish myeloproliferative neoplasm patients with a focus on overall and thrombosis free survival
Validation and interpretation of the Triple A model in Turkish myeloproliferative neoplasm patients with a focus on overall and thrombosis free survival
The Triple A model has recently been developed and validated in essential thrombocythemia (ET) and polycythemia vera (PV)....
Primary hyaline vascular Castleman disease in the kidney: a report and brief literature review
Primary hyaline vascular Castleman disease in the kidney: a report and brief literature review
Castleman disease is an uncommon lymphoproliferative disorder that usually involves lymph nodes but can rarely present in ...
A novel splicing variant of :: in myeloid/lymphoid neoplasm with eosinophilia and rearrangement of
A novel splicing variant of :: in myeloid/lymphoid neoplasm with eosinophilia and rearrangement of
Background Myeloid/lymphoid neoplasm with eosinophilia and rearrangement of FGFR1(MLN-FGFR1), also referred to as...
IgG4 plasma cells in hematopathology: beyond IgG4-related disease
IgG4 plasma cells in hematopathology: beyond IgG4-related disease
IgG4 plasma cells are well-known in the context of IgG4-related disease (IgG4-RD). Meanwhile, their role in other disorder...
A novel fusion associated with inversion of chromosome 7, inv(7)(p13q32), in relapsed acute myeloid leukemia
A novel fusion associated with inversion of chromosome 7, inv(7)(p13q32), in relapsed acute myeloid leukemia
Acute myeloid leukemia (AML) is characterized by myeloid blasts in the bone marrow and peripheral blood, and it is a highl...
Rare variant hemoglobin Köln in Southern India—an underdiagnosed entity?
Rare variant hemoglobin Köln in Southern India—an underdiagnosed entity?
We report a 15-year-old boy from Karnataka, India, initially misdiagnosed as HbE/β-thalassemia. On follow-up, Capilla...
From famine to feast: a seesawing platelet count in severe iron deficiency anemia
From famine to feast: a seesawing platelet count in severe iron deficiency anemia
A 22-month-old previously healthy girl presented with profound microcytic anemia and severe thrombocytopenia due to iron d...
Acute promyelocytic leukemia with a rare fusion and distinctive morphologic and phenotypic attributes
Acute promyelocytic leukemia with a rare fusion and distinctive morphologic and phenotypic attributes
Acute promyelocytic leukemias (APL) with variant translocations involving the RARA gene at 17q21.2 with non-PML partners c...
Mantle cell lymphoma transformation to CD19-negative classic Hodgkin lymphoma as a novel mechanism of escape from CD19 chimeric antigen receptor T cell therapy
Mantle cell lymphoma transformation to CD19-negative classic Hodgkin lymphoma as a novel mechanism of escape from CD19 chimeric antigen receptor T cell therapy
Mantle cell lymphoma (MCL) is a mature B cell neoplasm characterized by the CCND1::IgH t(11;14) translocation. The process...
Intrasinusoidal ALK-positive anaplastic large cell lymphoma
Intrasinusoidal ALK-positive anaplastic large cell lymphoma
ALK-positive anaplastic large cell lymphoma (ALCL) may show sinusoidal involvement, but exclusive intrasinusoidal infiltra...
Immunohistochemical evaluation of T cell receptor and T cell receptor beta constant 1 expression distinguishes benign and neoplastic immature T-cell populations and reveals discrete TRBC1/TCR phenotypes
Immunohistochemical evaluation of T cell receptor and T cell receptor beta constant 1 expression distinguishes benign and neoplastic immature T-cell populations and reveals discrete TRBC1/TCR phenotypes
Expression of TRBC1 and TRBC2 is increasingly assessed in the evaluation for clonal T-cell populations. While flow cytomet...
Acute myeloid leukemia with bipotential erythroid and megakaryocytic differentiation: a case series and literature review
Acute myeloid leukemia with bipotential erythroid and megakaryocytic differentiation: a case series and literature review
Acute myeloid leukemia with erythroid and megakaryocytic differentiation (AML-EMD) is a rare and aggressive presentation o...
Rare CD138 negative plasma cell leukemia with pleomorphic morphology—CD319 to the rescue when traditional markers fail
Rare CD138 negative plasma cell leukemia with pleomorphic morphology—CD319 to the rescue when traditional markers fail
Flow cytometric identification of plasma cells can be confounded by therapeutic anti-CD38 antibodies, a phenomenon commonl...
A pleura-based follicular dendritic cell sarcoma with epithelioid morphology and aberrant expression of cytokeratins
A pleura-based follicular dendritic cell sarcoma with epithelioid morphology and aberrant expression of cytokeratins
Follicular dendritic cell sarcoma (FDCS) is a rare mesenchymal neoplasm arising from the follicular dendritic cells (FDC) ...
B-cell acute lymphoblastic leukemia following myelodysplastic syndromes: a case report and literature review
B-cell acute lymphoblastic leukemia following myelodysplastic syndromes: a case report and literature review
Myelodysplastic syndromes (MDS) comprise clonal hematopoietic stem cell disorders characterized by heterogeneous clinical ...
Leukemic appendix with clinical presentation that mimics acute appendicitis
Leukemic appendix with clinical presentation that mimics acute appendicitis
Acute myeloid leukemia (AML) is a malignant neoplasm characterized by the uncontrolled, clonal growth of hematopoietic cel...
A case of transient monoclonal plasma cell aberrancy following respiratory syncytial virus (RSV) vaccination
A case of transient monoclonal plasma cell aberrancy following respiratory syncytial virus (RSV) vaccination
Plasma cell neoplasms include a spectrum of disorders ranging from monoclonal gammopathy of undetermined significance to m...
Morphologic findings and mutational profiles of myelodysplastic neoplasms with normal versus abnormal karyotype
Morphologic findings and mutational profiles of myelodysplastic neoplasms with normal versus abnormal karyotype
Myelodysplastic syndromes are clonal bone marrow failure disorders demonstrating variable degrees of cytopenias, morpholog...
The importance of bone marrow biopsy for chronic myeloid leukemia classification—a case report
The importance of bone marrow biopsy for chronic myeloid leukemia classification—a case report
Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the BCR::ABL1 rearrangement, usually diag...
Nucleolated cells in extranodal marginal zone lymphoma: a case report and discussion of circulating lymphoma cells with prominent nucleoli
Nucleolated cells in extranodal marginal zone lymphoma: a case report and discussion of circulating lymphoma cells with prominent nucleoli
Various types of lymphoma/leukemia can present with leukemic involvement by neoplastic cells with prominent nucleoli. Pati...
Demystifying the evaluation of a “dry tap”
Demystifying the evaluation of a “dry tap”
“Dry tap” refers to the failed aspiration of bone marrow hematopoietic elements. Faulty technique is frequentl...
Day + 100 bone marrow megakaryocyte count predicts transplant outcome in patients with high-risk myelodysplastic syndrome and acute leukemia
Day + 100 bone marrow megakaryocyte count predicts transplant outcome in patients with high-risk myelodysplastic syndrome and acute leukemia
Megakaryocytes (MKs), the precursor cells of platelets, have essential roles in a variety of pathophysiological processes ...
Mantle cell lymphoma with a prominent intrasinusoidal pattern of bone marrow involvement and circulating “prolymphocytoid” cells: an unusual pathological presentation posing diagnostic pitfalls
Mantle cell lymphoma with a prominent intrasinusoidal pattern of bone marrow involvement and circulating “prolymphocytoid” cells: an unusual pathological presentation posing diagnostic pitfalls
Ethical approval All procedures performed in studies involv...
The t(18;22)/:: translocation defines a unique CLL subtype: association with early treatment initiation
The t(18;22)/:: translocation defines a unique CLL subtype: association with early treatment initiation
The most prevalent BCL2 fusion in B-cell lymphoma involves the IGH gene, attributable to the t(14;18)(q32;q21) translocati...
Variant allele fraction or copy-neutral loss of heterozygosity? A comparison of testing platforms in the classification of myeloid neoplasia
Variant allele fraction or copy-neutral loss of heterozygosity? A comparison of testing platforms in the classification of myeloid neoplasia
Myelodysplastic syndrome (MDS) and myelodysplastic/myeloproliferative neoplasm (MDS/MPN) classification requires integrati...
Reed-Sternberg cell-like morphologic variant of B-lymphoblastic leukemia
Reed-Sternberg cell-like morphologic variant of B-lymphoblastic leukemia
Ethical approval This article does not contain any studies ...
A case of acid sphingomyelinase deficiency type B with prominent histiocytes with engulfed nucleated cells and compound heterozygosity
A case of acid sphingomyelinase deficiency type B with prominent histiocytes with engulfed nucleated cells and compound heterozygosity
Acid sphingomyelinase deficiency type B (ASMD-B), also known as Niemann-Pick type B (NPB), is caused by inherited mutation...
A rare case of B-cell acute lymphoblastic leukemia with translocation (14;14)(q11.2;q32) involving and with review of the literature
A rare case of B-cell acute lymphoblastic leukemia with translocation (14;14)(q11.2;q32) involving and with review of the literature
Translocation (14;14)(q11;q32) with immunoglobulin heavy chain (IGH) (14q32) and CCAAT enhancer-binding protein (CEBPE) (1...
Exploring castleman disease in a cohort of hispanic patients: a recognition to its histopathology
Exploring castleman disease in a cohort of hispanic patients: a recognition to its histopathology
Castleman disease is a clinicopathological entity that shares features with hematological, rheumatological, and infectious...
CD5-positive B-cell acute lymphoblastic leukemia/lymphoma with mimicking aggressive mature B-cell lymphoma: a case report of a newly described entity and potential diagnostic pitfall
CD5-positive B-cell acute lymphoblastic leukemia/lymphoma with mimicking aggressive mature B-cell lymphoma: a case report of a newly described entity and potential diagnostic pitfall
Here, we present a challenging diagnostic case of a B-cell acute lymphoblastic leukemia (B-ALL) presenting as a rare extra...
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