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Network pharmacology analysis and experimental validation of modified Taohong Siwu decoction against atherosclerosis
Network pharmacology analysis and experimental validation of modified Taohong Siwu decoction against atherosclerosis
The modified Taohong Siwu decoction (MTHSWD), a traditional prescription, demonstrates notable efficacy in treating cardio...
Dynamics of viability and apoptotic regulation in chicken ileal explant culture
Dynamics of viability and apoptotic regulation in chicken ileal explant culture
The development of a reliable ex vivo intestinal model is essential for studying gut physiology and host–microbe int...
VEGFA is essential for the potentiation of ATRA on BMP9-induced osteogenesis of preadipocytes and osteoporotic fracture healing
VEGFA is essential for the potentiation of ATRA on BMP9-induced osteogenesis of preadipocytes and osteoporotic fracture healing
The induction of osteogenic differentiation in preadipocytes may serve as a potential therapeutic approach for treating os...
The differential expression of lipocalin-2 in pig tissues and its molecular mechanism of regulating cell viability, differentiation, adipogenesis, and glycometabolism in porcine intramuscular preadipocytes
The differential expression of lipocalin-2 in pig tissues and its molecular mechanism of regulating cell viability, differentiation, adipogenesis, and glycometabolism in porcine intramuscular preadipocytes
Lipocalin-2 (LCN-2) is an adipocytokine secreted mainly by adipose tissue. Increasing evidences suggest that LCN-2 is an i...
Mechanisms of Xinwei Tang in stress-induced gastric dysmotility: evidence from rat and In Vitro models
Mechanisms of Xinwei Tang in stress-induced gastric dysmotility: evidence from rat and In Vitro models
Stress is a key trigger of gastric dysmotility, partly via mitochondrial dysfunction and disordered gut–brain hormon...
Comparative pathophysiological modeling: the advantage of “two-hit” over “one-hit” in acute liver failure studies
Comparative pathophysiological modeling: the advantage of “two-hit” over “one-hit” in acute liver failure studies
Acute liver failure (ALF), a life-threatening condition marked by rapid hepatocyte death and systemic inflammation, poses ...
A preliminary study on the mechanism of stromal interaction molecule 1 (STIM1) involvement in Adriamycin-induced podocyte injury
A preliminary study on the mechanism of stromal interaction molecule 1 (STIM1) involvement in Adriamycin-induced podocyte injury
Cellular metabolic reprogramming is intimately linked to various physiological and pathological processes. For instance, c...
The chitosan collagen salvianolic membrane mitigates intervertebral disc degeneration through suppression of the Wnt/β-catenin signaling
The chitosan collagen salvianolic membrane mitigates intervertebral disc degeneration through suppression of the Wnt/β-catenin signaling
Intervertebral disc degeneration (IVDD), a natural aging process, leads to intervertebral disc pain, with lumbar resection...
miR-495-3p attenuates cerebral ischemia-reperfusion-induced neuronal inflammation and apoptosis by targeting CCL2 expression
miR-495-3p attenuates cerebral ischemia-reperfusion-induced neuronal inflammation and apoptosis by targeting CCL2 expression
This study aimed to explore the function of miR-495-3p in cerebral ischemia-reperfusion injury (CI/RI) and reveal its pote...
Construction of tissue-engineered vascular sinoatrial node in vitro
Construction of tissue-engineered vascular sinoatrial node in vitro
To develop a biological pacemaker by differentiating rabbit BMSCs into vascular endothelial cells (VECs) and pacemaker-lik...
Decorin inhibits the migration and invasion of the LPS + high glucose–induced primary trophoblast cell through ADAMTS12
Decorin inhibits the migration and invasion of the LPS + high glucose–induced primary trophoblast cell through ADAMTS12
Decorin was identified as the most relevant biomarker in type 2 diabetes or obesity-related diseases, but its function in ...
Mechanism of LPS-activated gingival fibroblasts promote the migration of gastric cancer cells via CXCL12/CXCR4-Snail2-EMT axis
Mechanism of LPS-activated gingival fibroblasts promote the migration of gastric cancer cells via CXCL12/CXCR4-Snail2-EMT axis
The objective of this article is to explore the influence and process by which periodontitis affects the metastasis of gas...
Elevated intravesical pressure promotes circulating tumor cell release in an orthotopic mouse model of bladder cancer
Elevated intravesical pressure promotes circulating tumor cell release in an orthotopic mouse model of bladder cancer
Elevated intravesical pressure during transurethral resection of bladder tumor (TURBT) is hypothesized to facilitate the r...
miR-3614-5p prevents endothelial differentiation and angiogenesis in human exfoliated deciduous teeth by targeting lysophosphatidic acid receptor 2
miR-3614-5p prevents endothelial differentiation and angiogenesis in human exfoliated deciduous teeth by targeting lysophosphatidic acid receptor 2
The contribution of microRNAs (miRNAs) to the endothelial differentiation of stem cells from human exfoliated deciduous te...
Ginsenoside F1 ameliorates nonalcoholic fatty liver disease by activating the AMPK/PGC-1α pathway and autophagy
Ginsenoside F1 ameliorates nonalcoholic fatty liver disease by activating the AMPK/PGC-1α pathway and autophagy
Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver diseases globally, and currently, the...
In vitro culture for long-term maintenance of embryonic insect cells from the house cricket
In vitro culture for long-term maintenance of embryonic insect cells from the house cricket
Insect cell culture has become foundational for many areas of research and biotechnological innovation, yet major taxonomi...
Correction: The effect of IGF-1 on cartilage injury in bone marrow mesenchymal stem cells through the BMP2-Smad1/5 signaling pathway
Correction: The effect of IGF-1 on cartilage injury in bone marrow mesenchymal stem cells through the BMP2-Smad1/5 signaling pathway
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License...
Cabozantinib activates TFEB-mediated autophagy to exert anti-tumor effects in hepatocellular carcinoma
Cabozantinib activates TFEB-mediated autophagy to exert anti-tumor effects in hepatocellular carcinoma
Autophagy signaling plays a crucial yet complex role in hepatocellular carcinoma (HCC), influencing tumor progression and ...
Integrated assessment of graphene oxide and graphitic carbon nitride nanoparticles: from synthesis to in vitro biological impact on zebrafish () cell models
Integrated assessment of graphene oxide and graphitic carbon nitride nanoparticles: from synthesis to in vitro biological impact on zebrafish () cell models
Graphene and its derivatives have been increasingly explored for various biomedical applications. Despite their promising ...
RYK silencing-modified bone marrow-derived mesenchymal stem cells suppress gastric cancer progression
RYK silencing-modified bone marrow-derived mesenchymal stem cells suppress gastric cancer progression
Gastric cancer (GC) is a prevalent malignant tumor threatening human health. This study aimed to explore the potential mec...
Identification and characterization of the Dmrt1B gene in the oriental river prawn,
Identification and characterization of the Dmrt1B gene in the oriental river prawn,
Dmrt (doublesex and mab-3 related transcription factor) is a protein family of transcription factors implicated in sexual ...
From bristle to brain: embryonic development of topographic projections from basiconic sensilla in the antennal nervous system of the locust
From bristle to brain: embryonic development of topographic projections from basiconic sensilla in the antennal nervous system of the locust
The antennal flagellum of the locust S. gregaria is an articulated structure bearing a spectrum of sensilla that responds ...
Unveiling the cell dynamics during the final shape formation of the tarsus in adult leg by live imaging
Unveiling the cell dynamics during the final shape formation of the tarsus in adult leg by live imaging
Organisms display a remarkable diversity in their shapes. Although substantial progress has been made in unraveling the me...
Effects of two -knockout strains on the morphology and behavior in zebrafish
Effects of two -knockout strains on the morphology and behavior in zebrafish
The chromodomain helicase DNA binding domain 2 (CHD2) gene is an ATPase and a member of the SNF2-like family of helicase-r...
Molecular evolution and genetic diversity of in and (Diptera, Tephritidae)
Molecular evolution and genetic diversity of in and (Diptera, Tephritidae)
The family Tephritidae comprises numerous fruit fly species, some of which are economically significant, such as several i...
Silencing of blocks tail regeneration, but does not induce head regeneration in the flatworm
Silencing of blocks tail regeneration, but does not induce head regeneration in the flatworm
β-Catenin has two major functions conserved across metazoans. It enables the interaction of classical cadherin with a...
Early expression of chelicerate orthologs and its bearing on the homology of arthropod head segments
Early expression of chelicerate orthologs and its bearing on the homology of arthropod head segments
Evolution and development of the arthropod head are heavily debated topics often referred to as “The arthropod head ...
Sex-type specification and meristem development in fern gametophytes
Sex-type specification and meristem development in fern gametophytes
Sex determination, involving the physiological and morphological separation of male and female gamete-producing structures...
expression in the protonephridial system and foot neurons of the rotifer
expression in the protonephridial system and foot neurons of the rotifer
The homeobox gene engrailed is a multifunctional regulator with diverse developmental roles across Bilateria, ranging from...
Mapping micromere fate in the clitellate annelid
Mapping micromere fate in the clitellate annelid
In spiralians, the relationship between early cleavage patterns and the establishment of the juvenile body plan remains on...
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