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5-Methoxytryptophan improves cerebrovascular injury induced by chronic kidney disease through NF-κB pathway
5-Methoxytryptophan improves cerebrovascular injury induced by chronic kidney disease through NF-κB pathway
5-Methoxytryptophan (5-MTP), a candidate biomarker for chronic kidney disease (CKD), has an undefined role in cerebrovascu...
Cyto-genotoxic assessment of bisphenol P through expression of DNA damage/repair genes in MDBK cell line
Cyto-genotoxic assessment of bisphenol P through expression of DNA damage/repair genes in MDBK cell line
Bisphenol P (BPP) is a recognized endocrine disruptor with detrimental effects on human health. This study aimed to evalua...
Bone marrow–derived mesenchymal stem cells and their extracellular vesicles suppress splenocyte activation and ameliorate experimental autoimmune encephalomyelitis
Bone marrow–derived mesenchymal stem cells and their extracellular vesicles suppress splenocyte activation and ameliorate experimental autoimmune encephalomyelitis
Multiple sclerosis (MS) is a neurodegenerative and autoimmune disease affecting the central nervous system (CNS). Recently...
Adhesion extracellular matrix proteins improve in vitro cellular and functional properties of enriched caprine adult dermal fibroblast
Adhesion extracellular matrix proteins improve in vitro cellular and functional properties of enriched caprine adult dermal fibroblast
The study was supported by a grant from the National Livestock Mission (NLM) (Grant No. R-99011(11)9/2022-DADF-Dept (E-232...
Functions of ectodysplasin A2 receptor (EDA2R) in inducing capacitation of sperm in mice
Functions of ectodysplasin A2 receptor (EDA2R) in inducing capacitation of sperm in mice
Sperm capacitation, a prerequisite for fertilization, is regulated not only by intrinsic signaling but also by paracrine f...
Role of PDGFRα-mediated signalling in anoikis resistance in glioblastoma: in vitro study
Role of PDGFRα-mediated signalling in anoikis resistance in glioblastoma: in vitro study
Anoikis resistance, the evasion of programmed cell death when cells detach from the extracellular matrix (ECM), is a criti...
Exploring the effects of roscovitine, serum starvation, and contact inhibition at G/G arrest in northern tiger cat dermal fibroblasts
Exploring the effects of roscovitine, serum starvation, and contact inhibition at G/G arrest in northern tiger cat dermal fibroblasts
Nuclear reprogramming studies are important tools in conserving wild felids, with efficacy depending on efficient G0/G1 ce...
Establishment of a method to evaluate the dynamics of highly chemotactic THP-1 cells during differentiation into monocyte-M1 macrophage-like cells
Establishment of a method to evaluate the dynamics of highly chemotactic THP-1 cells during differentiation into monocyte-M1 macrophage-like cells
Differentiation of the human monocytic leukemia cell line THP-1 is widely used to analyze the function of monocyte/macroph...
Nuclear protein 1 protects against neonatal hypoxic-ischemic encephalopathy by inhibiting neuronal ferroptosis by improving iron storage
Nuclear protein 1 protects against neonatal hypoxic-ischemic encephalopathy by inhibiting neuronal ferroptosis by improving iron storage
Recent studies have highlighted the role of ferroptosis in neuronal damage during neonatal hypoxic-ischemic encephalopathy...
Optimization of a protocol for the high-yield isolation of active muscle stem cells from bovine skeletal muscle tissue
Optimization of a protocol for the high-yield isolation of active muscle stem cells from bovine skeletal muscle tissue
Beef is primarily made up of skeletal muscle tissue. Therefore, the cultivation of bovine muscle stem cells (MSCs) to prov...
Therapeutic potential of miR-10a overexpressing mesenchymal stem cell–derived extracellular vesicles in modulating inflammation in collagen-induced arthritis
Therapeutic potential of miR-10a overexpressing mesenchymal stem cell–derived extracellular vesicles in modulating inflammation in collagen-induced arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune condition that leads to joint damage. Mesenchymal stem cells (MSCs) are ...
KHDRBS3-mediated upregulation of circ_0024107 in gastric cancer cells and GC-MSCs synergistically drives gastric cancer cell migration and invasion
KHDRBS3-mediated upregulation of circ_0024107 in gastric cancer cells and GC-MSCs synergistically drives gastric cancer cell migration and invasion
Gastric cancer is a significant global health concern due to its high morbidity and mortality. Gastric cancer-associated m...
promotes lactoferrin synthesis and secretion in bovine mammary epithelial cells through STAT3 and AP-1 transcription factor pathways
promotes lactoferrin synthesis and secretion in bovine mammary epithelial cells through STAT3 and AP-1 transcription factor pathways
Probiotics can support the immune function of dairy cows and contribute to the synthesis of milk components in mammary gla...
ALDH4A1 knockdown inhibits in vitro atherosclerosis model by modulating Trim28-mediated P53 ubiquitination to suppress ferroptosis of vascular endothelial cells
ALDH4A1 knockdown inhibits in vitro atherosclerosis model by modulating Trim28-mediated P53 ubiquitination to suppress ferroptosis of vascular endothelial cells
Atherosclerosis (AS) is a primary contributor to cardiovascular disease (CVD), resulting in high mortality. Ferroptosis, t...
ATF4 regulates PI3K/AKT signaling axis to promote angiogenesis after myocardial infarction
ATF4 regulates PI3K/AKT signaling axis to promote angiogenesis after myocardial infarction
Effective neovascularization is critical for tissue repair and the enhancement of cardiac function following myocardial in...
Therapeutic targeting of Nrf2/HO-1/NF-κB signaling axis with casticin mitigates intervertebral disc degeneration: in vitro and in vivo investigations
Therapeutic targeting of Nrf2/HO-1/NF-κB signaling axis with casticin mitigates intervertebral disc degeneration: in vitro and in vivo investigations
As a persistent osteoarticular degenerative condition, intervertebral disc deterioration (IDD) has been established as a p...
Fetal bovine serum in cryomedia protects sheep spermatogonial stem cells and preserves stemness characteristics during cryopreservation
Fetal bovine serum in cryomedia protects sheep spermatogonial stem cells and preserves stemness characteristics during cryopreservation
Baust JM, Corwin W, Snyder KK, Van Buskirk R, Baust JG (2016) Cryopreservation: evolution of molecular based strategies. A...
Inhibition of cGAS-STING signaling pathway alleviates high glucose-induced mesothelial-mesenchymal transition in human peritoneal mesothelial cell line HMrSV5
Inhibition of cGAS-STING signaling pathway alleviates high glucose-induced mesothelial-mesenchymal transition in human peritoneal mesothelial cell line HMrSV5
The mesothelial-mesenchymal transition (MMT) of peritoneal mesothelial cells is a critical factor contributing to the prog...
LncRNA TP53TG1 promotes the growth and osteo/dentinogenic differentiation of dental pulp stem cells by activating the Smad3 and JNK1/2 pathway
LncRNA TP53TG1 promotes the growth and osteo/dentinogenic differentiation of dental pulp stem cells by activating the Smad3 and JNK1/2 pathway
TP53TG1 is a long non-coding RNA related to the TP53 gene, which plays an important role in various biological processes s...
Correction: The adaptation of bovine embryonic stem cells to the changes of feeder layers
Correction: The adaptation of bovine embryonic stem cells to the changes of feeder layers
Correction: In Vitro Cellular & Developmental Biology - Animal (2023) 59:85-99The...
MiR-146a-5p downregulated TRAF6/NF-κB p65 pathway to attenuate the injury of HT-22 cells induced by oxygen–glucose deprivation/reoxygenation
MiR-146a-5p downregulated TRAF6/NF-κB p65 pathway to attenuate the injury of HT-22 cells induced by oxygen–glucose deprivation/reoxygenation
MicroRNA-146a-5p (miR-146a-5p) actively participates in the process of cerebral ischemia–reperfusion (CI/R) injury. ...
Development and characterization of polyvinyl alcohol/gelatin/chitosan hydrogel for tissue engineering and wound healing applications using a fish cell line model
Development and characterization of polyvinyl alcohol/gelatin/chitosan hydrogel for tissue engineering and wound healing applications using a fish cell line model
Chitosan-based hydrogels have gained considerable attention in biomedical research due to their inherent biocompatibility,...
Maxing Yigan formula promotes cartilage regeneration by regulating chondrocyte autophagy in osteoarthritis
Maxing Yigan formula promotes cartilage regeneration by regulating chondrocyte autophagy in osteoarthritis
Maxing Yigan formula (MYF) is a traditional Chinese medicine (TCM) prescription used for the treatment of OA for decades i...
OPA3 inhibits the cGAS-STING pathway mediated by mtDNA stress to promote colorectal cancer progression
OPA3 inhibits the cGAS-STING pathway mediated by mtDNA stress to promote colorectal cancer progression
Colorectal cancer (CRC) is an extremely harmful malignant tumor. Optic atrophy 3 (OPA3) is highly expressed in multiple tu...
Expression, prognosis, immunological infiltration, and DNA methylation of members of the SFRP gene family in colorectal cancer: a comparative bioinformatic and experimental analysis
Expression, prognosis, immunological infiltration, and DNA methylation of members of the SFRP gene family in colorectal cancer: a comparative bioinformatic and experimental analysis
This study aimed to investigate the expression, prognostic significance, methylation, and immune invasion levels of secret...
Preliminary study on the potential damage of cigarette smoke extract in 3D human chondrocyte culture
Preliminary study on the potential damage of cigarette smoke extract in 3D human chondrocyte culture
Osteoarthritis (OA) is a chronic degenerative disease characterized by the progressive loss of articular cartilage. The ro...
Efficacy determination of a disinfectant against channel catfish virus by in vitro and in vivo methods
Efficacy determination of a disinfectant against channel catfish virus by in vitro and in vivo methods
Channel catfish virus (CCV) poses a significant threat to catfish culture. Lack of effective vaccines and antiviral treatm...
Urolithin B suppresses phenotypic switch in vascular smooth muscle cells induced by PDGF-BB via inhibiting the PI3K-AKT pathway
Urolithin B suppresses phenotypic switch in vascular smooth muscle cells induced by PDGF-BB via inhibiting the PI3K-AKT pathway
Atherosclerosis (AS) is a prevalent cardiovascular condition, and the growth and phenotypic switch of vascular smooth musc...
Tianxiangdan suppresses foam cell formation by enhancing lipophagy and reduces the progression of atherosclerosis
Tianxiangdan suppresses foam cell formation by enhancing lipophagy and reduces the progression of atherosclerosis
The aim of this study is to assess the impact of Tianxiangdan (TXD) on lipophagy in foam cells and its underlying mechanis...
Melatonin inhibits ferroptosis through the ATF3/GPX4 signaling pathway to relieve myocardial ischemia–reperfusion injury in rats
Melatonin inhibits ferroptosis through the ATF3/GPX4 signaling pathway to relieve myocardial ischemia–reperfusion injury in rats
Melatonin (MEL), functioning as a circulating hormone, is important for the regulation of ferroptosis in different health ...
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