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Intussusceptive angiogenesis: bridging in vivo and in vitro observations
Intussusceptive angiogenesis: bridging in vivo and in vitro observations
Staples SCR, Yin H, Sutherland FSK, Prescott EK, Tinney D, Hamilton DW, Goldman D, Poepping TL, Ellis CG, Pickering JG (20...
Revealing the unseen: 3D synchrotron X-Ray imaging of uterine vasculature in adenomyosis
Revealing the unseen: 3D synchrotron X-Ray imaging of uterine vasculature in adenomyosis
Authors and AffiliationsDepartment of Obstetrics and Gynecology, Amsterdam UMC location University of Amsterdam, Meibergdr...
BMP9 knockout impairs pulmonary vessel muscularisation and confers aberrant tamoxifen sensitivity
BMP9 knockout impairs pulmonary vessel muscularisation and confers aberrant tamoxifen sensitivity
Deleterious mutations in the GDF2 gene, encoding BMP9, are causative of pulmonary arterial hypertension and hereditary hae...
Endothelial LRRC8A mitigates pressure overload-induced cardiac hypertrophy by promoting coronary angiogenesis
Endothelial LRRC8A mitigates pressure overload-induced cardiac hypertrophy by promoting coronary angiogenesis
Clinical evidence has indicated that pressure overload-induced cardiac hypertrophy is closely linked with adverse cardiac ...
Hydroxychloroquine does not affect endotheliopathy or coagulopathy biomarkers in COVID-19: longitudinal results from the  randomized trial
Hydroxychloroquine does not affect endotheliopathy or coagulopathy biomarkers in COVID-19: longitudinal results from the randomized trial
Hydroxychloroquine (HCQ), long used for its immunomodulatory and vasculoprotective properties in autoimmune diseases such ...
Genetic and pharmacological targeting of mTORC1 in mouse models of arteriovenous malformation expose non-cell autonomous signalling in HHT
Genetic and pharmacological targeting of mTORC1 in mouse models of arteriovenous malformation expose non-cell autonomous signalling in HHT
Arteriovenous malformations (AVMs) are abnormal high flow shunts between arteries and veins with major negative impact on ...
Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
Neuropilin-1 (NRP1) regulates endothelial cell (EC) biology through modulation of vascular endothelial growth factor recep...
Effect of oral nintedanib vs placebo on epistaxis in hereditary hemorrhagic telangiectasia: the EPICURE multicenter randomized double-blind trial
Effect of oral nintedanib vs placebo on epistaxis in hereditary hemorrhagic telangiectasia: the EPICURE multicenter randomized double-blind trial
Epistaxis greatly affects patients with hereditary hemorrhagic telangiectasia (HHT). Although few systemic treatment exist...
Anti-angiogenic therapy as potential treatment for adenomyosis
Anti-angiogenic therapy as potential treatment for adenomyosis
Adenomyosis is characterized by abnormal uterine bleeding, dysmenorrhea and subfertility. Increased expression of angiogen...
From bench to bedside: murine models of inherited and sporadic brain arteriovenous malformations
From bench to bedside: murine models of inherited and sporadic brain arteriovenous malformations
Brain arteriovenous malformations are abnormal vascular structures in which an artery shunts high pressure blood directly ...
Correction: Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
Correction: Neuropilin-1 controls vascular permeability through juxtacrine regulation of endothelial adherens junctions
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, whi...
Cxcl9 modulates aging associated microvascular metabolic and angiogenic dysfunctions in subcutaneous adipose tissue
Cxcl9 modulates aging associated microvascular metabolic and angiogenic dysfunctions in subcutaneous adipose tissue
Microvascular aging, predominantly driven by endothelial cells (ECs) dysfunction, is a critical early event in cardiovascu...
Isolated human adipose microvessels retain native microvessel structure and recapitulate sprouting angiogenesis
Isolated human adipose microvessels retain native microvessel structure and recapitulate sprouting angiogenesis
With interest growing in modeling more complex aspects of human disease in the laboratory, the need for effectively vascul...
Immune-privileged cord blood-derived endothelial colony-forming cells: advancing immunomodulation and vascular regeneration
Immune-privileged cord blood-derived endothelial colony-forming cells: advancing immunomodulation and vascular regeneration
Cord blood-derived endothelial colony-forming cells (CB-ECFCs) hold significant promise for regenerative medicine due to t...
Endothelial USP11 drives VEGFR2 signaling and angiogenesis via PRDX2/c-MYC axis
Endothelial USP11 drives VEGFR2 signaling and angiogenesis via PRDX2/c-MYC axis
Angiogenesis is a crucial component of various physiological and pathological processes, including embryonic development, ...
ApoM-bound S1P acts via endothelial S1PR1 to suppress choroidal neovascularization and vascular leakage
ApoM-bound S1P acts via endothelial S1PR1 to suppress choroidal neovascularization and vascular leakage
Neovascular age-related macular degeneration (nAMD) is a major cause of vision loss worldwide. Current standard of care is...
Role of endothelial PDGFB in arterio-venous malformations pathogenesis
Role of endothelial PDGFB in arterio-venous malformations pathogenesis
Arterial-venous malformations (AVMs) are direct connections between arteries and veins without an intervening capillary be...
Circulating Von Willebrand factor: a consistent biomarker predicting in-hospital mortality across different waves of the COVID-19 pandemic
Circulating Von Willebrand factor: a consistent biomarker predicting in-hospital mortality across different waves of the COVID-19 pandemic
Paris Cité University, Innovative Therapies in Hemostasis, INSERM, 75006, Paris, FranceDavid M. Smadja, Aurélien Philippe,...
Multimodality imaging reveals angiogenic evolution in vivo during calvarial bone defect healing
Multimodality imaging reveals angiogenic evolution in vivo during calvarial bone defect healing
The healing of calvarial bone defects is a pressing clinical problem that involves the dynamic interplay between angiogene...
Correction: The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells
Correction: The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells
The Fig. 3a of this article originally contained an incorrect picture showing “HDAC7/AKAP12 siRNA” condition at t = 0 h. I...
Notch ligands are biomarkers of anti-TNF response in RA patients
Notch ligands are biomarkers of anti-TNF response in RA patients
Notch and its ligands play a critical role in rheumatoid arthritis (RA) pathogenesis. Hence, studies were conducted to del...
Targeting the microenvironment in the treatment of arteriovenous malformations
Targeting the microenvironment in the treatment of arteriovenous malformations
Extracranial arteriovenous malformations (AVMs) are regarded as rare diseases and are prone to complications such as pain,...
Executive summary of the 14th HHT international scientific conference
Executive summary of the 14th HHT international scientific conference
Hereditary Hemorrhagic Telangiectasia (HHT) is an autosomal dominant vascular disorder characterized by small, dilated clu...
A defined clathrin-mediated trafficking pathway regulates sFLT1/VEGFR1 secretion from endothelial cells
A defined clathrin-mediated trafficking pathway regulates sFLT1/VEGFR1 secretion from endothelial cells
FLT1/VEGFR1 negatively regulates VEGF-A signaling and is required for proper vessel morphogenesis during vascular developm...
2022 14th HHT International Scientific Conference Abstracts
2022 14th HHT International Scientific Conference Abstracts
Medical therapeuticsO1 Cure HHT research network: building the roadmap to cure HHTFriday C, MS1; Krock N1; Schaefer N1; Le...