Amilpur S, Bhukya R (2022) Predicting novel drug candidates against Covid-19 using generative deep neural networks. J Mol Graph Model 110:108045. https://doi.org/10.1016/j.jmgm.2021.108045
Article CAS PubMed Google Scholar
Atabaki-Pasdar N, Ohlsson M, Viñuela A, Frau F, Pomares-Millan H, Haid M, Jones AG, Thomas EL, Koivula RW, Kurbasic A, Mutie PM, Fitipaldi H, Fernandez J, Dawed AY, Giordano GN, Forgie IM, Mcdonald TJ, Rutters F, Cederberg H, Chabanova E, Dale M, Masi F, Thomas CE, Allin KH, Hansen TH, Heggie A, Hong MG, Elders PJM, Kennedy G, Kokkola T, Pedersen HK, Mahajan A, Mcevoy D, Pattou F, Raverdy V, Häussler RS, Sharma S, Thomsen HS, Vangipurapu J, Vestergaard H, T Hart LM, Adamski J, Musholt PB, Brage S, Brunak S, Dermitzakis E, Frost G, Hansen T, Laakso M, Pedersen O, Ridderstråle M, Ruetten H, Hattersley AT, Walker M, Beulens JWJ, Mari A, Schwenk JM, Gupta R, Mccarthy MI, Pearson ER, Bell JD, Pavo I, Franks PW (2020) Predicting and elucidating the etiology of fatty liver disease: a machine learning modeling and validation study in the IMI DIRECT cohorts. PLoS Med 17:e1003149. https://doi.org/10.1371/journal.pmed.1003149
Article CAS PubMed PubMed Central Google Scholar
Barrett T, Wilhite SE, Ledoux P, Evangelista C, Kim IF, Tomashevsky M, Marshall KA, Phillippy KH, Sherman PM, Holko M, Yefanov A, Lee H, Zhang N, Robertson CL, Serova N, Davis S, Soboleva A (2013) Ncbi geo: archive for functional genomics data sets–update. Nucleic Acids Res 41:D991-995. https://doi.org/10.1093/nar/gks1193
Article CAS PubMed Google Scholar
Blanc V, Riordan JD, Soleymanjahi S, Nadeau JH, Nalbantoglu I, Xie Y, Molitor EA, Madison BB, Brunt EM, Mills JC, Rubin DC, Ng IO, Ha Y, Roberts LR, Davidson NO (2021) Apobec1 complementation factor overexpression promotes hepatic steatosis, fibrosis, and hepatocellular cancer. J Clin Invest. https://doi.org/10.1172/jci138699
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J, Hentze MW (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 149:1393–1406. https://doi.org/10.1016/j.cell.2012.04.031
Article CAS PubMed Google Scholar
Castello A, Fischer B, Frese CK, Horos R, Alleaume AM, Foehr S, Curk T, Krijgsveld J, Hentze MW (2016) Comprehensive identification of RNA-binding domains in human cells. Mol Cell 63:696–710. https://doi.org/10.1016/j.molcel.2016.06.029
Article CAS PubMed PubMed Central Google Scholar
Chen L, Li J, Zhang J, Dai C, Liu X, Wang J, Gao Z, Guo H, Wang R, Lu S, Wang F, Zhang H, Chen H, Fan X, Wang S, Qin Z (2015) S100A4 promotes liver fibrosis via activation of hepatic stellate cells. J Hepatol 62:156–164. https://doi.org/10.1016/j.jhep.2014.07.035
Article CAS PubMed Google Scholar
Chen B, Zheng YM, Zhang MQ, Han Y, Zhang JP, Hu CQ (2019) Microarray expression profiling and Raman spectroscopy reveal anti-fatty liver action of berberine in a diet-induced larval zebrafish model. Front Pharmacol 10:1504. https://doi.org/10.3389/fphar.2019.01504
Article CAS PubMed Google Scholar
Cheng R, Wang L, Le S, Yang Y, Zhao C, Zhang X, Yang X, Xu T, Xu L, Wiklund P, Ge J, Lu D, Zhang C, Chen L, Cheng S (2022) A randomized controlled trial for response of microbiome network to exercise and diet intervention in patients with nonalcoholic fatty liver disease. Nat Commun 13:2555. https://doi.org/10.1038/s41467-022-29968-0
Article CAS PubMed PubMed Central Google Scholar
Chu WK, Hung LM, Hou CW, Chen JK (2021) PKC regulates YAP expression through alternative splicing of YAP 3’UTR pre-mRNA by hnRNP F. Int J Mol Sci. https://doi.org/10.3390/ijms22020694
Article PubMed PubMed Central Google Scholar
Del Río-Moreno M, Alors-Pérez E, González-Rubio S, Ferrín G, Reyes O, Rodríguez-Perálvarez M, Sánchez-Frías ME, Sánchez-Sánchez R, Ventura S, López-Miranda J, Kineman RD, De La Mata M, Castaño JP, Gahete MD, Luque RM (2019) Dysregulation of the splicing machinery is associated to the development of nonalcoholic fatty liver disease. J Clin Endocrinol Metab 104:3389–3402. https://doi.org/10.1210/jc.2019-00021
Article PubMed PubMed Central Google Scholar
Dolicka D, Zahoran S, Correia De Sousa M, Gjorgjieva M, Sempoux C, Fournier M, Maeder C, Collart MA, Foti M, Sobolewski C (2022) TIA1 loss exacerbates fatty liver disease but exerts a dual role in hepatocarcinogenesis. Cancers (Basel). https://doi.org/10.3390/cancers14071704
Feng H, Liu J, Qiu Y, Liu Y, Saiyin H, Liang X, Zheng F, Wang Y, Jiang D, Wang Y, Yu L, Su W, Shen S, Wu J (2020) RNA-binding motif protein 43 (RBM43) suppresses hepatocellular carcinoma progression through modulation of cyclin B1 expression. Oncogene 39:5495–5506. https://doi.org/10.1038/s41388-020-1380-7
Article CAS PubMed Google Scholar
Gerstberger S, Hafner M, Tuschl T (2014) A census of human RNA-binding proteins. Nat Rev Genet 15:829–845. https://doi.org/10.1038/nrg3813
Article CAS PubMed PubMed Central Google Scholar
Guo XF, Gao JL, Li JM, Li D (2017) Fat-1 mice prevent high-fat plus high-sugar diet-induced non-alcoholic fatty liver disease. Food Funct 8:4053–4061. https://doi.org/10.1039/c7fo01050h
Article CAS PubMed Google Scholar
Hartwig J, Loebel M, Steiner S, Bauer S, Karadeniz Z, Roeger C, Skurk C, Scheibenbogen C, Sotzny F (2021) Metformin attenuates ROS via FOXO3 activation in immune cells. Front Immunol 12:581799. https://doi.org/10.3389/fimmu.2021.581799
Article CAS PubMed PubMed Central Google Scholar
Hentze MW, Castello A, Schwarzl T, Preiss T (2018) A brave new world of RNA-binding proteins. Nat Rev Mol Cell Biol 19:327–341. https://doi.org/10.1038/nrm.2017.130
Article CAS PubMed Google Scholar
Hoang SA, Oseini A, Feaver RE, Cole BK, Asgharpour A, Vincent R, Siddiqui M, Lawson MJ, Day NC, Taylor JM, Wamhoff BR, Mirshahi F, Contos MJ, Idowu M, Sanyal AJ (2019) Gene expression predicts histological severity and reveals distinct molecular profiles of nonalcoholic fatty liver disease. Sci Rep 9:12541. https://doi.org/10.1038/s41598-019-48746-5
Article CAS PubMed PubMed Central Google Scholar
Horvat P, Richards M, Kubinova R, Pajak A, Malyutina S, Shishkin S, Pikhart H, Peasey A, Marmot MG, Singh-Manoux A, Bobak M (2015) Alcohol consumption, drinking patterns, and cognitive function in older Eastern European adults. Neurology 84:287–295. https://doi.org/10.1212/wnl.0000000000001164
Article CAS PubMed PubMed Central Google Scholar
Jafri Z, Li Y, Zhang J, O’meara CH, Khachigian LM (2025) Jun, an oncological foe or friend? Int J Mol Sci 26:555. https://doi.org/10.3390/ijms26020555
Article CAS PubMed PubMed Central Google Scholar
Jiang H, Zhu H, Huo G, Li S, Wu Y, Zhou F, Hua C, Hu Q (2022) Oudemansiella raphanipies polysaccharides improve lipid metabolism disorders in murine high-fat diet-induced non-alcoholic fatty liver disease. Nutrients. https://doi.org/10.3390/nu14194092
Article PubMed PubMed Central Google Scholar
Kim GW, Jo HK, Chung SH (2018) Ginseng seed oil ameliorates hepatic lipid accumulation in vitro and in vivo. J Ginseng Res 42:419–428. https://doi.org/10.1016/j.jgr.2017.04.010
Kumar D, Das M, Sauceda C, Ellies LG, Kuo K, Parwal P, Kaur M, Jih L, Bandyopadhyay GK, Burton D, Loomba R, Osborn O, Webster NJ (2019) Degradation of splicing factor SRSF3 contributes to progressive liver disease. J Clin Invest 129:4477–4491. https://doi.org/10.1172/jci127374
Article PubMed PubMed Central Google Scholar
Kwok R, Tse YK, Wong GL, Ha Y, Lee AU, Ngu MC, Chan HL, Wong VW (2014) Systematic review with meta-analysis: non-invasive assessment of non-alcoholic fatty liver disease–the role of transient elastography and plasma cytokeratin-18 fragments. Aliment Pharmacol Ther 39:254–269. https://doi.org/10.1111/apt.12569
Article CAS PubMed Google Scholar
Lee CY, Hsin MC, Chen PN, Lin CW, Wang PH, Yang SF, Hsiao YH (2022a) Arctiin inhibits cervical cancer cell migration and invasion through suppression of S100A4 expression via PI3K/Akt pathway. Pharmaceutics. https://doi.org/10.3390/pharmaceutics14020365
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