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A Guide to Pathophysiology, Signaling Pathways, and Preclinical Models of Liver Fibrosis
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Functional analysis of SRY variants in individuals with 46,XY Differences of Sex Development.
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EDNRB negatively regulates glycolysis to exhibit anti-tumor functions in prostate cancer by cGMP/PKG pathway
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Transcriptomic Analysis of Effects of Developmental PCB Exposure in the Hypothalamus of Female Rats
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Genetic loss of Uchl1 leads to female infertility by affecting oocyte quality and follicular development
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NAT10 drives endometriosis progression through acetylation and stabilization of TGFB1 mRNA
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MDPAO1 peptide from human milk enhances brown adipose tissue thermogenesis and mitigates obesity
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USP7 promotes decidualization of ESCs by STAT3/PR axis during early pregnancy
USP7 promotes decidualization of ESCs by STAT3/PR axis during early pregnancy
A prospective human pregnancy requires successful implantation and decidualization, which are two critically orchestrated ...
Nrf2 inhibition regulates intracellular lipid accumulation in mouse insulinoma cells and improves insulin secretory function
Nrf2 inhibition regulates intracellular lipid accumulation in mouse insulinoma cells and improves insulin secretory function
Obesity and overweight can raise the risk of type 2 diabetes (T2D). A high amount of fat in the pancreas, known as intrapa...
Endosomal signaling via cAMP in parathyroid hormone (PTH) type 1 receptor biology
Endosomal signaling via cAMP in parathyroid hormone (PTH) type 1 receptor biology
Available online 20 November 2023, 112107Author links open overlay panel, , AbstractCompartmentalization of GPCR signaling...
A MUFA/carotenoid-rich oil ameliorated insulin resistance by improving inflammation and oxidative stress in obese rats
A MUFA/carotenoid-rich oil ameliorated insulin resistance by improving inflammation and oxidative stress in obese rats
Obesity is characterized by excessive fat accumulation in adipose tissue, and its origin is multifactorial. The excessive ...
The BRAFV600E mutation maintains the aggressiveness of papillary thyroid cancers requiring downregulation of primary cilia
The BRAFV600E mutation maintains the aggressiveness of papillary thyroid cancers requiring downregulation of primary cilia
Papillary thyroid cancers (PTCs) account for more than 80% of all thyroid cancers (TCs). PTC generally has an indolent nat...
Novel regulatory roles of small G protein GDP dissociation stimulator (smgGDS) in insulin secretion from pancreatic β-cells
Novel regulatory roles of small G protein GDP dissociation stimulator (smgGDS) in insulin secretion from pancreatic β-cells
It is well established that GSIS from pancreatic β-cells requires the generation of soluble second messengers including cy...
Male-specific vasotocin expression in the medaka tuberal hypothalamus: Androgen dependence and probable role in aggression
Male-specific vasotocin expression in the medaka tuberal hypothalamus: Androgen dependence and probable role in aggression
Aggression is an adaptive behavioral trait that is crucial for competition for territories, food, and mating partners and ...
Activation of mitophagy improves cognitive dysfunction in diabetic mice with recurrent non-severe hypoglycemia
Activation of mitophagy improves cognitive dysfunction in diabetic mice with recurrent non-severe hypoglycemia
Maintaining blood sugar level is critical for the management of patients with diabetes. However, accidental recurrent exce...
Deregulation of ABCG1 early in life contributes to prostate carcinogenesis in maternally malnourished offspring rats
Deregulation of ABCG1 early in life contributes to prostate carcinogenesis in maternally malnourished offspring rats
Over the past decades, the incidence of non-communicable chronic diseases (NCDs), such as cardiovascular diseases, respira...