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USP37 promotes diffuse large B-cell lymphoma progression by deubiquitinating and stabilizing c-myc
USP37 promotes diffuse large B-cell lymphoma progression by deubiquitinating and stabilizing c-myc
A poorer prognosis is thought to be associated with “double expressor lymphomas,” which are a subtype of diffu...
Silencing miR-126-5p protects trabecular meshwork cells against chronic oxidative injury by upregulating HSPB8 to activate PI3K/AKT pathway
Silencing miR-126-5p protects trabecular meshwork cells against chronic oxidative injury by upregulating HSPB8 to activate PI3K/AKT pathway
Chronic oxidative stress (COS) is related to the pathophysiology of the trabecular meshwork (TM) in glaucoma. MicroRNAs (m...
Bolanthus turcicus: a promising antidiabetic with in-vitro antioxidant, enzyme inhibitory and antiadipogenic activities
Bolanthus turcicus: a promising antidiabetic with in-vitro antioxidant, enzyme inhibitory and antiadipogenic activities
It is crucial to investigate new anti-diabetic agents and therapeutic approaches targeting molecules in potential signalin...
Signaling pathway regulators in preimplantation embryos
Signaling pathway regulators in preimplantation embryos
Embryonic development during the preimplantation stages is highly sensitive and critically dependent on the reception of s...
Effects of Moringa oleifera extract on biochemical and histological parameters of sodium valproate induced lungs damage
Effects of Moringa oleifera extract on biochemical and histological parameters of sodium valproate induced lungs damage
Sodium valproate– a salt of valproic acid (VPA), is an anticonvulsant used in the treatment of epilepsy and a range ...
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the immune system maternal-fetal interface during palatal development
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the immune system maternal-fetal interface during palatal development
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is an important environmental pollutant that disturbs the immune balance of the...
Dendritic pathology and overexpression of MAP2 in Purkinje cells from mice inoculated with rabies virus
Dendritic pathology and overexpression of MAP2 in Purkinje cells from mice inoculated with rabies virus
The effect of rabies virus infection on dendritic morphology and on the expression of the MAP2 protein in Purkinje cells i...
UCF-101 ameliorates traumatic brain injury by promoting microglia M2 polarization via AMPK/NF-κB pathways in LPS-induced BV2 cells
UCF-101 ameliorates traumatic brain injury by promoting microglia M2 polarization via AMPK/NF-κB pathways in LPS-induced BV2 cells
Traumatic brain injury (TBI) is a common neurosurgical emergency. As a macrophage in brain, microglia involves in secondar...
mir-330-5p from mesenchymal stem cell-derived exosomes targets SETD7 to reduce inflammation in rats with cerebral ischemia-reperfusion injury
mir-330-5p from mesenchymal stem cell-derived exosomes targets SETD7 to reduce inflammation in rats with cerebral ischemia-reperfusion injury
This study was to investigate the role of microRNA (miR)-330-5p derived from mesenchymal stem cells-secreted exosomes (MSC...
Immunohistochemical evaluation of LGR5, CD71, CD138 and CXCR3 markers in the small bowel mucosa of participants with celiac disease and persons with normal bowel mucosa
Immunohistochemical evaluation of LGR5, CD71, CD138 and CXCR3 markers in the small bowel mucosa of participants with celiac disease and persons with normal bowel mucosa
Celiac disease (CD) is a chronic autoimmune disease of the small bowel mucosa that develops because of the altered immune ...
Additional benefits of combined ceftriaxone and adipose-derived mesenchymal stem cells on revamping the outcomes in rodent after acute spinal infection
Additional benefits of combined ceftriaxone and adipose-derived mesenchymal stem cells on revamping the outcomes in rodent after acute spinal infection
This study tested whether combined ceftriaxone and adipose-derived mesenchymal stem cells (ADMSCs) would defend the spinal...
The potential ameliorative effect of mesenchymal stem cells-derived exosomes on cerebellar histopathology and their modifying role on PI3k-mTOR signaling in rat model of autism spectrum disorder
The potential ameliorative effect of mesenchymal stem cells-derived exosomes on cerebellar histopathology and their modifying role on PI3k-mTOR signaling in rat model of autism spectrum disorder
Autism spectrum disorder (ASD) is a group of severe neurodevelopmental disorders. This study aimed to elucidate the potent...
The potential role of SCF combined with DPCs in facial nerve repair
The potential role of SCF combined with DPCs in facial nerve repair
Facial nerve injuries lead to significant functional impairments and psychological distress for affected patients. Effecti...
Activation of the WNT4/ β-catenin/FOXO1 pathway by PDK1 promotes cervical cancer metastasis and EMT process
Activation of the WNT4/ β-catenin/FOXO1 pathway by PDK1 promotes cervical cancer metastasis and EMT process
This study aimed to elucidate the role of pyruvate dehydrogenase kinase-1 (PDK1) in cervical cancer (CC) by investigating ...
MiRNAs and tempol therapeutic potential in prostate cancer: a preclinical approach
MiRNAs and tempol therapeutic potential in prostate cancer: a preclinical approach
This study investigated tempol action on genes and miRNAs related to NFκB pathway in androgen dependent or independen...
Comparative analysis with stem cell therapy in rats with pharyngocutaneous fistula formation
Comparative analysis with stem cell therapy in rats with pharyngocutaneous fistula formation
Laryngocutaneous fistula is one of the most important complications encountered after larynx surgery. Stem cell therapy is...
LINC02418 suppresses endometrial cancer progression via regulating miR-494-3p/RASGRF1 axis
LINC02418 suppresses endometrial cancer progression via regulating miR-494-3p/RASGRF1 axis
Long non-coding RNAs (lncRNAs) have emerged as pivotal regulatory molecules in cancer biology. Among these, long intergeni...
LOC102549726/miR-760-3p network is involved in the progression of ISO-induced pathological cardiomyocyte hypertrophy via endoplasmic reticulum stress
LOC102549726/miR-760-3p network is involved in the progression of ISO-induced pathological cardiomyocyte hypertrophy via endoplasmic reticulum stress
Pathological cardiac hypertrophy (CH) is featured by myocyte enlargement and cardiac malfunction. Multiple signaling pathw...
Investigation of miR-26b and miR-27b expressions and the effect of quercetin on fibrosis in experimental pulmonary fibrosis
Investigation of miR-26b and miR-27b expressions and the effect of quercetin on fibrosis in experimental pulmonary fibrosis
In this study, investigation of the effects of Quercetin on Bleomycin-induced pulmonary fibrosis and fibrosis-associated m...
The circSNX14 functions as a tumor suppressor via the miR-562/ LATS2 pathway in hepatocellular carcinoma cells
The circSNX14 functions as a tumor suppressor via the miR-562/ LATS2 pathway in hepatocellular carcinoma cells
Circular RNAs (circRNAs) play critical roles in the initiation and progression of various cancers. However, the potential ...
Mitochondria as a target for exercise-mitigated type 2 diabetes
Mitochondria as a target for exercise-mitigated type 2 diabetes
Type 2 diabetes mellitus (T2DM) is one of most common metabolic diseases and continues to be a leading cause of death worl...
Effects of abnormal expression of CD73 on malignant phenotype of nasopharyngeal carcinoma
Effects of abnormal expression of CD73 on malignant phenotype of nasopharyngeal carcinoma
Cluster of differentiation (CD) 73, encoded by the NT5E gene, plays important enzymatic and non-enzymatic roles in cells. ...
Osteopontin: an essential regulatory protein in idiopathic pulmonary fibrosis
Osteopontin: an essential regulatory protein in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive, chronic lung disease characterized by abnormal proliferation and act...
Intra-articular delivery of geraniol encapsulated by pH/redox-responsive nanogel ameliorates osteoarthritis by regulating oxidative stress and inflammation
Intra-articular delivery of geraniol encapsulated by pH/redox-responsive nanogel ameliorates osteoarthritis by regulating oxidative stress and inflammation
Osteoarthritis (OA) remains a challenging condition due to limited drug bioavailability within the avascular and dense car...
The ratio of alpha-calcitonin gene-related peptide to substance P is associated with the transition of bone metabolic states during aging and healing
The ratio of alpha-calcitonin gene-related peptide to substance P is associated with the transition of bone metabolic states during aging and healing
Alpha-calcitonin gene-related peptide (αCGRP) and substance P (SP) are functionally correlated sensory neuropeptides ...
Serum HBV RNA levels among untreated adults with chronic hepatitis B in distinct immune phases and liver histopathology statuses
Serum HBV RNA levels among untreated adults with chronic hepatitis B in distinct immune phases and liver histopathology statuses
HBV RNA is a novel serum biomarker that reflects intrahepatic HBV covalently closed circular DNA (cccDNA) transcription ac...
Cdk1 protects against oxygen-glucose deprivation and reperfusion-induced Golgi fragmentation and apoptosis through mediating GM130 phosphorylation
Cdk1 protects against oxygen-glucose deprivation and reperfusion-induced Golgi fragmentation and apoptosis through mediating GM130 phosphorylation
Increasing evidence has indicated that the Golgi apparatus (GA) is involved in the development of cerebral ischemia–...
Dynamic patterns of histone lactylation during early tooth development in mice
Dynamic patterns of histone lactylation during early tooth development in mice
Histone lactylation on its lysine (K) residues has been reported to have indispensable roles in lung fibrosis, embryogenes...
ERO1α promotes the proliferation and inhibits apoptosis of colorectal cancer cells by regulating the PI3K/AKT pathway
ERO1α promotes the proliferation and inhibits apoptosis of colorectal cancer cells by regulating the PI3K/AKT pathway
Endoplasmic reticulum oxidoreductin 1α (ERO1α) is an oxidase that exists in the endoplasmic reticulum and plays ...
Three-dimensional visualization of the lymphatic, vascular and neural network in rat lung by confocal microscopy
Three-dimensional visualization of the lymphatic, vascular and neural network in rat lung by confocal microscopy
In order to demonstrate the intricate interconnection of pulmonary lymphatic vessels, blood vessels, and nerve fibers, the...
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