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CEP78 regulates the proliferation and angiogenesis of endothelial cells by mediating microtubule stabilization via p150glued
CEP78 regulates the proliferation and angiogenesis of endothelial cells by mediating microtubule stabilization via p150glued
Angiogenesis, the sprouting of neovasculature from established vessels, is an essential biological process for wound heali...
Nature’s shield: ginseng as a neuroprotective agent against titanium dioxide nanoparticle exposure
Nature’s shield: ginseng as a neuroprotective agent against titanium dioxide nanoparticle exposure
Titanium dioxide nanoparticles (TiO₂-NPs) are widely used in various industries due to their unique properties. Howe...
Dihydromyricetin protects hippocampal neurons in sepsis-associated encephalopathy by reducing ER stress-mediated apoptosis and inflammation
Dihydromyricetin protects hippocampal neurons in sepsis-associated encephalopathy by reducing ER stress-mediated apoptosis and inflammation
Sepsis-associated encephalopathy (SAE) involves hippocampal dysfunction and cognitive deficits, but its underlying mechani...
Ferroptosis: a novel pathway in the pathogenesis and treatment of endometriosis
Ferroptosis: a novel pathway in the pathogenesis and treatment of endometriosis
As a common chronic disease, endometriosis (EMs) affects nearly 10% of women of childbearing age, may cause other complica...
Hippo signaling pathway in human testis and seminoma: anticancer effect of verteporfin on human seminoma TCam-2 cells
Hippo signaling pathway in human testis and seminoma: anticancer effect of verteporfin on human seminoma TCam-2 cells
Seminoma and embryonal carcinoma are among the most common germ cell tumors. Verteporfin, a YAP-TEAD inhibitor, has emerge...
Immunohistochemical examination of CD163 and TROP2 expression levels in ovarian endometriosis
Immunohistochemical examination of CD163 and TROP2 expression levels in ovarian endometriosis
Endometriosis is described as an estrogen-associated, chronic, inflammatory disorder characterized by ectopic endometrial ...
NLRP3 promotes NK cell-mediated cytotoxicity and inhibits colorectal cancer development via the NKG2D signaling pathway
NLRP3 promotes NK cell-mediated cytotoxicity and inhibits colorectal cancer development via the NKG2D signaling pathway
Colorectal cancer progression involves tumor metastasis and immune evasion, with the NOD-like receptor family, pyrin domai...
Prenatal and pubertal exposure to ethinylestradiol induces Long-Term stromal and epithelial changes in the gerbil dorsal prostate
Prenatal and pubertal exposure to ethinylestradiol induces Long-Term stromal and epithelial changes in the gerbil dorsal prostate
17α-Ethinylestradiol (EE2) is a synthetic estrogen derived from 17β-estradiol and widely used in oral contracept...
Ephrin-B1 and EphB4 expression and localization in steroidogenic cells of mouse adrenal gland
Ephrin-B1 and EphB4 expression and localization in steroidogenic cells of mouse adrenal gland
Erythropoietin-producing hepatocellular (Eph) receptors and their ligands ephrin are membrane-bound molecules that modulat...
Voacangine targeting of PI3K/Akt/ERK via the knockdown of inflammation in DEN-induced liver cancer: in vivo and in silico approach
Voacangine targeting of PI3K/Akt/ERK via the knockdown of inflammation in DEN-induced liver cancer: in vivo and in silico approach
Hepatocellular carcinoma (HCC) is a type of primary liver cancer characterized by inflammation and liver damage. It is a s...
Kurarinone protects against renal injury and fibrosis after unilateral ureteral obstruction through enhancement of the Nrf-2 signaling pathway
Kurarinone protects against renal injury and fibrosis after unilateral ureteral obstruction through enhancement of the Nrf-2 signaling pathway
Chronic kidney disease (CKD) is an epidemic with higher cardiovascular risk, and this pathology involves renal injury and ...
Therapeutic potential of derivatized carbon dots in ameliorating chemotherapy-induced anemia
Therapeutic potential of derivatized carbon dots in ameliorating chemotherapy-induced anemia
Aplastic anemia, a prevalent disorder of the hematopoietic system, may develop as a result of bone marrow suppression indu...
Gallic acid enhanced reproductive function by modulating oxidative stress mediators in gentamicin-treated rats
Gallic acid enhanced reproductive function by modulating oxidative stress mediators in gentamicin-treated rats
Gentamicin (GEN), commonly used to treat gram-negative bacterial infections, can cause testicular damage, maybe by increas...
Coenzyme Q10 may protect ovarian tissue against by the nearly century-old drug methotrexate caused gonadotoxicity: a biochemical, flow cytometric, and histopathological study
Coenzyme Q10 may protect ovarian tissue against by the nearly century-old drug methotrexate caused gonadotoxicity: a biochemical, flow cytometric, and histopathological study
Methotrexate (MTX) is still a broad-spectrum drug that has been used for almost a century for leukemia, rheumatoid arthrit...
USP37 promotes diffuse large B-cell lymphoma progression by deubiquitinating and stabilizing c-myc
USP37 promotes diffuse large B-cell lymphoma progression by deubiquitinating and stabilizing c-myc
A poorer prognosis is thought to be associated with “double expressor lymphomas,” which are a subtype of diffu...
Silencing miR-126-5p protects trabecular meshwork cells against chronic oxidative injury by upregulating HSPB8 to activate PI3K/AKT pathway
Silencing miR-126-5p protects trabecular meshwork cells against chronic oxidative injury by upregulating HSPB8 to activate PI3K/AKT pathway
Chronic oxidative stress (COS) is related to the pathophysiology of the trabecular meshwork (TM) in glaucoma. MicroRNAs (m...
Bolanthus turcicus: a promising antidiabetic with in-vitro antioxidant, enzyme inhibitory and antiadipogenic activities
Bolanthus turcicus: a promising antidiabetic with in-vitro antioxidant, enzyme inhibitory and antiadipogenic activities
It is crucial to investigate new anti-diabetic agents and therapeutic approaches targeting molecules in potential signalin...
Signaling pathway regulators in preimplantation embryos
Signaling pathway regulators in preimplantation embryos
Embryonic development during the preimplantation stages is highly sensitive and critically dependent on the reception of s...
Effects of Moringa oleifera extract on biochemical and histological parameters of sodium valproate induced lungs damage
Effects of Moringa oleifera extract on biochemical and histological parameters of sodium valproate induced lungs damage
Sodium valproate– a salt of valproic acid (VPA), is an anticonvulsant used in the treatment of epilepsy and a range ...
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the immune system maternal-fetal interface during palatal development
Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the immune system maternal-fetal interface during palatal development
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is an important environmental pollutant that disturbs the immune balance of the...
Dendritic pathology and overexpression of MAP2 in Purkinje cells from mice inoculated with rabies virus
Dendritic pathology and overexpression of MAP2 in Purkinje cells from mice inoculated with rabies virus
The effect of rabies virus infection on dendritic morphology and on the expression of the MAP2 protein in Purkinje cells i...
UCF-101 ameliorates traumatic brain injury by promoting microglia M2 polarization via AMPK/NF-κB pathways in LPS-induced BV2 cells
UCF-101 ameliorates traumatic brain injury by promoting microglia M2 polarization via AMPK/NF-κB pathways in LPS-induced BV2 cells
Traumatic brain injury (TBI) is a common neurosurgical emergency. As a macrophage in brain, microglia involves in secondar...
mir-330-5p from mesenchymal stem cell-derived exosomes targets SETD7 to reduce inflammation in rats with cerebral ischemia-reperfusion injury
mir-330-5p from mesenchymal stem cell-derived exosomes targets SETD7 to reduce inflammation in rats with cerebral ischemia-reperfusion injury
This study was to investigate the role of microRNA (miR)-330-5p derived from mesenchymal stem cells-secreted exosomes (MSC...
Immunohistochemical evaluation of LGR5, CD71, CD138 and CXCR3 markers in the small bowel mucosa of participants with celiac disease and persons with normal bowel mucosa
Immunohistochemical evaluation of LGR5, CD71, CD138 and CXCR3 markers in the small bowel mucosa of participants with celiac disease and persons with normal bowel mucosa
Celiac disease (CD) is a chronic autoimmune disease of the small bowel mucosa that develops because of the altered immune ...
Additional benefits of combined ceftriaxone and adipose-derived mesenchymal stem cells on revamping the outcomes in rodent after acute spinal infection
Additional benefits of combined ceftriaxone and adipose-derived mesenchymal stem cells on revamping the outcomes in rodent after acute spinal infection
This study tested whether combined ceftriaxone and adipose-derived mesenchymal stem cells (ADMSCs) would defend the spinal...
The potential ameliorative effect of mesenchymal stem cells-derived exosomes on cerebellar histopathology and their modifying role on PI3k-mTOR signaling in rat model of autism spectrum disorder
The potential ameliorative effect of mesenchymal stem cells-derived exosomes on cerebellar histopathology and their modifying role on PI3k-mTOR signaling in rat model of autism spectrum disorder
Autism spectrum disorder (ASD) is a group of severe neurodevelopmental disorders. This study aimed to elucidate the potent...
The potential role of SCF combined with DPCs in facial nerve repair
The potential role of SCF combined with DPCs in facial nerve repair
Facial nerve injuries lead to significant functional impairments and psychological distress for affected patients. Effecti...
Activation of the WNT4/ β-catenin/FOXO1 pathway by PDK1 promotes cervical cancer metastasis and EMT process
Activation of the WNT4/ β-catenin/FOXO1 pathway by PDK1 promotes cervical cancer metastasis and EMT process
This study aimed to elucidate the role of pyruvate dehydrogenase kinase-1 (PDK1) in cervical cancer (CC) by investigating ...
MiRNAs and tempol therapeutic potential in prostate cancer: a preclinical approach
MiRNAs and tempol therapeutic potential in prostate cancer: a preclinical approach
This study investigated tempol action on genes and miRNAs related to NFκB pathway in androgen dependent or independen...
Comparative analysis with stem cell therapy in rats with pharyngocutaneous fistula formation
Comparative analysis with stem cell therapy in rats with pharyngocutaneous fistula formation
Laryngocutaneous fistula is one of the most important complications encountered after larynx surgery. Stem cell therapy is...
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