Ahechu P, Zozaya G, Martí P, Hernández-Lizoáin JL, Baixauli J, Unamuno X, Frühbeck G, Catalán V (2018) NLRP3 inflammasome: a possible link between obesity-associated low-grade chronic inflammation and colorectal cancer development. Front Immunol 9:2918. https://doi.org/10.3389/fimmu.2018.02918
Article CAS PubMed PubMed Central Google Scholar
Carreira-Santos S, López-Sejas N, González-Sánchez M, Sánchez-Hernández E, Pera A, Hassouneh F, Durán E, Solana R, Casado JG, Tarazona R (2023) Enhanced expression of natural cytotoxicity receptors on cytokine-induced memory-like natural killer cells correlates with effector function. Front Immunol 14:1256404. https://doi.org/10.3389/fimmu.2023.1256404
Article CAS PubMed PubMed Central Google Scholar
Chang YH, Connolly J, Shimasaki N, Mimura K, Kono K, Campana D (2013) A chimeric receptor with NKG2D specificity enhances natural killer cell activation and killing of tumor cells. Cancer Res 73:1777–1786. https://doi.org/10.1158/0008-5472.Can-12-3558
Article CAS PubMed Google Scholar
Chen S, Li X, Chen R, Yin M, Zheng Q (2016) Cetuximab intensifies the ADCC activity of adoptive NK cells in a nude mouse colorectal cancer xenograft model. Oncol Lett 12:1868–1876. https://doi.org/10.3892/ol.2016.4835
Article CAS PubMed PubMed Central Google Scholar
Chow MT, Sceneay J, Paget C, Wong CS, Duret H, Tschopp J, Möller A, Smyth MJ (2012) NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases. Cancer Res 72:5721–5732. https://doi.org/10.1158/0008-5472.Can-12-0509
Article CAS PubMed Google Scholar
Dhar P, Wu JD (2018) NKG2D and its ligands in cancer. Curr Opin Immunol 51:55–61. https://doi.org/10.1016/j.coi.2018.02.004
Article CAS PubMed PubMed Central Google Scholar
Dietsch GN, Lu H, Yang Y, Morishima C, Chow LQ, Disis ML, Hershberg RM (2016) Coordinated activation of toll-like receptor8 (TLR8) and NLRP3 by the TLR8 agonist, VTX-2337, ignites tumoricidal natural killer cell activity. PLoS One 11:e0148764. https://doi.org/10.1371/journal.pone.0148764
Article CAS PubMed PubMed Central Google Scholar
Dupaul-Chicoine J, Arabzadeh A, Dagenais M, Douglas T, Champagne C, Morizot A, Rodrigue-Gervais IG, Breton V, Colpitts SL, Beauchemin N, Saleh M (2015) The Nlrp3 inflammasome suppresses colorectal cancer metastatic growth in the liver by promoting natural killer cell tumoricidal activity. Immunity 43:751–763. https://doi.org/10.1016/j.immuni.2015.08.013
Article CAS PubMed Google Scholar
Ferrari de Andrade L, Tay RE, Pan D, Luoma AM, Ito Y, Badrinath S, Tsoucas D, Franz B, May KF Jr., Harvey CJ, Kobold S, Pyrdol JW, Yoon C, Yuan GC, Hodi FS, Dranoff G, Wucherpfennig KW (2018) Antibody-mediated Inhibition of MICA and MICB shedding promotes NK cell-driven tumor immunity. Science (New York, NY) 359:1537–1542. https://doi.org/10.1126/science.aao0505
Fernández-Torres J, Zamudio-Cuevas Y, Ruiz-Dávila X, López-Macay A, Martínez-Flores K (2024) MICA and NLRP3 gene polymorphisms interact synergistically affecting the risk of ankylosing spondylitis. Immunol Res 72:119–127. https://doi.org/10.1007/s12026-023-09419-8
Article CAS PubMed Google Scholar
Fuertes MB, Domaica CI, Zwirner NW (2021) Leveraging NKG2D ligands in immuno-oncology. Front Immunol 12:713158. https://doi.org/10.3389/fimmu.2021.713158
Article CAS PubMed PubMed Central Google Scholar
Gao Z, Jiang J, Hou L. and, Zhang B (2022) Dysregulation of MiR-144-5p/RNF187 axis contributes to the progression of colorectal cancer. J Transl Intern Med 10:65–75. https://doi.org/10.2478/jtim-2021-0043
Guan X, Liu R, Wang B, Xiong R, Cui L, Liao Y, Ruan Y, Fang L, Lu X, Yu X, Su D, Ma Y, Dang T, Chen Z, Yao Y, Liu C, Zhang Y (2024) Inhibition of HDAC2 sensitises antitumour therapy by promoting NLRP3/GSDMD-mediated pyroptosis in colorectal cancer. Clin Transl Med 14:e1692. https://doi.org/10.1002/ctm2.1692
Article CAS PubMed PubMed Central Google Scholar
Hou Y, Jin J, Duan H, Liu C, Chen L, Huang W, Gao Z, Jin M (2022) Targeted therapeutic effects of oral inulin-modified double-layered nanoparticles containing chemotherapeutics on orthotopic colon cancer. Biomaterials 283:121440. https://doi.org/10.1016/j.biomaterials.2022.121440
Article CAS PubMed Google Scholar
Huang Y, Wang H, Hao Y, Lin H, Dong M, Ye J, Song L, Wang Y, Li Q, Shan B, Jiang Y, Li H, Shao Z, Kroemer G, Zhang H, Bai L, Jin T, Wang C, Ma Y, Cai Y, Ding C, Liu S, Pan Y, Jiang W, Zhou R (2020) Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity. Nat Cell Biol 22:716–727. https://doi.org/10.1038/s41556-020-0510-3
Article CAS PubMed Google Scholar
Khandia R, Munjal A (2020) Interplay between inflammation and cancer. Adv Protein Chem Struct Biol 119:199–245. https://doi.org/10.1016/bs.apcsb.2019.09.004
Article CAS PubMed Google Scholar
Kumar V, Hertz M, Agro A, Byrne AJ (2023) Type 1 invariant natural killer T cells in chronic inflammation and tissue fibrosis. Front Immunol 14:1260503. https://doi.org/10.3389/fimmu.2023.1260503
Article CAS PubMed PubMed Central Google Scholar
Kummer JA, Broekhuizen R, Everett H, Agostini L, Kuijk L, Martinon F, Van Bruggen R, Tschopp J (2007) Inflammasome components NALP 1 and 3 show distinct but separate expression profiles in human tissues suggesting a site-specific role in the inflammatory response. J Histochem Cytochem 55:443–452. https://doi.org/10.1369/jhc.6A7101.2006
Article CAS PubMed Google Scholar
Lee HH, Kim D, Jung J, Kang H, Cho H (2021) NLRP3 deficiency in hepatocellular carcinoma enhances surveillance of NK-92 through a modulation of MICA/B. Int J Mol Sci 22:9285. https://doi.org/10.3390/ijms22179285
Li Y, Liu M, Zuo Z, Liu J, Yu X, Guan Y, Zhan R, Han Q, Zhang J, Zhou R, Sun R, Tian Z, Zhang C (2017) TLR9 regulates the NF-κB-NLRP3-IL-1β pathway negatively in Salmonella-Induced NKG2D-Mediated intestinal inflammation. J Immunol 199:761–773. https://doi.org/10.4049/jimmunol.1601416
Article CAS PubMed Google Scholar
Li T, Fu B, Zhang X, Zhou Y, Yang M, Cao M, Chen Y, Tan Y, Hu R (2021) Overproduction of gastrointestinal 5-HT promotes colitis-associated colorectal cancer progression via enhancing NLRP3 inflammasome activation. Cancer Immunol Res 9:1008–1023. https://doi.org/10.1158/2326-6066.Cir-20-1043
Liu X, Chen Q, Yan J, Wang Y, Zhu C, Chen C, Zhao X, Xu M, Sun Q, Deng R, Zhang H, Qu Y, Huang J, Jiang B, Yu J (2013) MiRNA-296-3p-ICAM-1 axis promotes metastasis of prostate cancer by possible enhancing survival of natural killer cell-resistant circulating tumour cells. Cell Death Dis 4:e928. https://doi.org/10.1038/cddis.2013.458
Article CAS PubMed PubMed Central Google Scholar
Man SM, Kanneganti TD (2015) Regulation of inflammasome activation. Immunol Rev 265:6–21. https://doi.org/10.1111/imr.12296
Article CAS PubMed PubMed Central Google Scholar
Papafragkos I, Grigoriou M, Boon L, Kloetgen A, Hatzioannou A, Verginis P (2022) Ablation of NLRP3 inflammasome rewires MDSC function and promotes tumor regression. Front Immunol 13:889075. https://doi.org/10.3389/fimmu.2022.889075
Article CAS PubMed PubMed Central Google Scholar
Raynaud A, Desrumeaux K, Vidard L, Termine E, Baty D, Chames P, Vigne E, Kerfelec B (2020) Anti-NKG2D single domain-based antibodies for the modulation of anti-tumor immune response. Oncoimmunology 10:1854529. https://doi.org/10.1080/2162402x.2020.1854529
Article CAS PubMed PubMed Central Google Scholar
Schreiber RD, Old LJ, Smyth MJ (2011) Cancer immunoediting: integrating immunity’s roles in cancer suppression and promotion. Science (New York, NY) 331:1565–1570. https://doi.org/10.1126/science.1203486
Sharma BR, Kanneganti TD (2021) NLRP3 inflammasome in cancer and metabolic diseases. Nat Immunol 22:550–559. https://doi.org/10.1038/s41590-021-00886-5
Article CAS PubMed PubMed Central Google Scholar
Sharma D, Malik A, Guy CS, Karki R, Vogel P, Kanneganti TD (2018) Pyrin inflammasome regulates tight junction integrity to restrict colitis and tumorigenesis. Gastroenterology 154:948–964e948. https://doi.org/10.1053/j.gastro.2017.11.276
Comments (0)