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Mechanisms of Lipid-Mediated Regulation of the Pore-Forming Activity of Antimicrobial Agents: Studies on Planar Lipid Bilayers
Mechanisms of Lipid-Mediated Regulation of the Pore-Forming Activity of Antimicrobial Agents: Studies on Planar Lipid Bilayers
Planar lipid bilayers are unique tools designed for modeling cell membranes and electrophysiological studies of ion channe...
Structure and Functions of the OTOP1 Proton Channel
Structure and Functions of the OTOP1 Proton Channel
OTOP1 belongs to the otopetrin family of membrane proteins that form proton channels in cells of diverse types. In mammals...
Role of Membrane H Transport and Plasmalemma Excitability in Pattern Formation, Long-Distance Transport and Photosynthesis of Characean Algae
Role of Membrane H Transport and Plasmalemma Excitability in Pattern Formation, Long-Distance Transport and Photosynthesis of Characean Algae
Illuminated giant cells of Characeae produce alternating areas with H+-pump activity and zones of high H+/OH– conduc...
Alterations of Store-Operated Calcium Entry in Neurodegenerative Pathologies: History, Facts, and Prospects
Alterations of Store-Operated Calcium Entry in Neurodegenerative Pathologies: History, Facts, and Prospects
Neurodegenerative diseases, along with cardiovascular and oncological pathologies, are one of the most acute problems of m...
Influence of Membrane Curvature on the Energy Barrier of Pore Formation
Influence of Membrane Curvature on the Energy Barrier of Pore Formation
Formation of through conducting defects—pores—in the lipid bilayer affects many processes in living cells and ...
Interaction of Albumin with Angiotensin-I-Converting Enzyme According to Molecular Modeling Data
Interaction of Albumin with Angiotensin-I-Converting Enzyme According to Molecular Modeling Data
Human serum albumin (HSA) is an endogenous inhibitor of angiotensin-I-converting enzyme (ACE), which is an integral membra...
Comparison of Spontaneous and Evoked Activity of CA1 Pyramidal Cells and Dentate Gyrus Granule Cells of the Hippocampus at an Increased Extracellular Potassium Concentration
Comparison of Spontaneous and Evoked Activity of CA1 Pyramidal Cells and Dentate Gyrus Granule Cells of the Hippocampus at an Increased Extracellular Potassium Concentration
In this work the effect of changing extracellular potassium concentration ([K+]o) on spontaneous and evoked burst activity...
Rapid Transfer of Photo-Released Protons from Water to Lipid Membrane
Rapid Transfer of Photo-Released Protons from Water to Lipid Membrane
The transport of protons between the membrane boundary and water can be hindered by the presence of a high potential barri...
Positive Effect of YB-1 and Mesenchymal Stromal Cells on Primary Hippocampal Culture under Conditions of ACE2 Receptor Blockade
Positive Effect of YB-1 and Mesenchymal Stromal Cells on Primary Hippocampal Culture under Conditions of ACE2 Receptor Blockade
Despite the fact that the current situation with COVID-19 incidence is not an emergency, new strains of SARS-CoV-2 coronav...
Cationic and Ionizable Amphiphiles Based on Dihexadecyl Ester of -Glutamic Acid for Liposomal Transport of RNA
Cationic and Ionizable Amphiphiles Based on Dihexadecyl Ester of -Glutamic Acid for Liposomal Transport of RNA
Various RNAs are among the most promising and actively developed therapeutic agents for the treatment of tumors, infectiou...
Electrostatic Potentials during Adsorption and Photochemical Reactions of Pyranine on Bilayer Lipid Membranes
Electrostatic Potentials during Adsorption and Photochemical Reactions of Pyranine on Bilayer Lipid Membranes
Adsorption and photochemical reactions of pyranine on a bilayer lipid membrane (BLM) have been studied by measuring electr...
Simulation of the Glycolytic Metabolite Concentration Profile in Mammalian Resting Skeletal Muscles
Simulation of the Glycolytic Metabolite Concentration Profile in Mammalian Resting Skeletal Muscles
A mathematical model of glycolysis in mammalian skeletal muscles is presented for the first time, in which stationary conc...
Approach for Analysis of Intracellular Markers in Phosphatidylserine-Positive Platelets
Approach for Analysis of Intracellular Markers in Phosphatidylserine-Positive Platelets
Phosphatidylserine- (PS-) positive platelets play an important role in thrombosis and hemostasis. They have high procoagul...
Distribution of Progesterone Receptors and the Membrane Component of the Progesterone Receptor in Various Organs and Tissues of Male and Female Rats
Distribution of Progesterone Receptors and the Membrane Component of the Progesterone Receptor in Various Organs and Tissues of Male and Female Rats
Progesterone regulates reproductive processes and affects many functions of various non-reproductive organs. Its effects i...
Immunofluorescent Identification of GABAergic Structures in the Somatic Muscle of the Earthworm Lumbricus terrestris
Immunofluorescent Identification of GABAergic Structures in the Somatic Muscle of the Earthworm Lumbricus terrestris
Using the immunofluorescence confocal microscopy, we detected the following GABAergic structures in the somatic muscle of ...
Force Characteristics of Yersinia pestis Lipopolysaccharide Interaction with TLR4 and CD14 Receptors on J774 Macrophages: Atomic Force Microscopy
Force Characteristics of Yersinia pestis Lipopolysaccharide Interaction with TLR4 and CD14 Receptors on J774 Macrophages: Atomic Force Microscopy
One of the main stages of the infectious process, which largely determines the course and outcome of the disease, is the p...
Lipid Membranes Electroporation Cannot Be Described by the Constant Line Tension Model of the Pore Edge
Lipid Membranes Electroporation Cannot Be Described by the Constant Line Tension Model of the Pore Edge
We have studied the process of electroporation of bilayer lipid membranes (BLMs) made of dioleoylphosphatidylcholine (DOPC...
Membrane-Active Mitochondria-Targeted Antitumor Agents and Drug Delivery Systems
Membrane-Active Mitochondria-Targeted Antitumor Agents and Drug Delivery Systems
Mitochondria are the “power stations” of cells. Without them, the normal functioning of a living cell is impos...
Effect of Auxin on Fatty Acid Composition and Activity of Acyl-Lipid Desaturases in Seedlings of Spring Wheat Triticum aestivum L.
Effect of Auxin on Fatty Acid Composition and Activity of Acyl-Lipid Desaturases in Seedlings of Spring Wheat Triticum aestivum L.
The effect of exogenous auxin on changes in the fatty acid composition of the total lipids of leaves and roots of spring w...
Comparison of Changes in the Content of Plasma Membrane and Tonoplast Sterols under Oxidative and Osmotic Stress
Comparison of Changes in the Content of Plasma Membrane and Tonoplast Sterols under Oxidative and Osmotic Stress
We compared oxidative and osmotic stress-induced changes in sterol content in plasma membranes and tonoplasts isolated fro...
Theoretical Explanation for the Variability in Platelet Activation through the GPVI Receptor
Theoretical Explanation for the Variability in Platelet Activation through the GPVI Receptor
One of the key receptors on the surface of platelets, non-nuclear cells responsible for preventing blood loss when blood v...
Application of N,N,N',N'-Tetramethyl-p-Phenylenediamine and α,ω-Hexadecanedioic Acid for Determination of the H+/O Ratios of Complexes III and IV of the Liver Mitochondrial Respiratory Chain under Free Respiration Conditions
Application of N,N,N',N'-Tetramethyl-p-Phenylenediamine and α,ω-Hexadecanedioic Acid for Determination of the H+/O Ratios of Complexes III and IV of the Liver Mitochondrial Respiratory Chain under Free Respiration Conditions
Stimulation of mitochondrial respiration in state 4 without changes in passive proton leakage is known to be accompanied b...
Mixed Cationic Liposomes Based on L-Amino Acids As Efficient Delivery Systems of Therapeutic Molecules into Cells
Mixed Cationic Liposomes Based on L-Amino Acids As Efficient Delivery Systems of Therapeutic Molecules into Cells
This work aimed to produce mixed liposomes based on natural amino acids as vehicles for delivery of anticancer drugs and n...
Benzimidazole Derivative NS1619 Inhibits Functioning of Mitochondria Isolated from Mouse Skeletal Muscle
Benzimidazole Derivative NS1619 Inhibits Functioning of Mitochondria Isolated from Mouse Skeletal Muscle
The activator of the large-conductance Ca2+-activated K+ channel (BKCa) NS1619 is known to have a pleiotropic action and i...
Activation of the Cannabinoid Receptors Suppresses Hyperexcitation of Rat Hippocampal Neuronal Networks In Vitro
Activation of the Cannabinoid Receptors Suppresses Hyperexcitation of Rat Hippocampal Neuronal Networks In Vitro
Cannabinoid receptors (CBRs) play a key role in various physiological processes, including neurogenesis, synaptic plastici...
BAR Domain Proteins as Putative Regulators of the Protein Liquid Phase in Nerve Terminals in the Central Nervous System
BAR Domain Proteins as Putative Regulators of the Protein Liquid Phase in Nerve Terminals in the Central Nervous System
BAR proteins are key components of the synaptic vesicle cycle in nerve terminals. They participate in the regulation of ne...
Electron Transport in Chloroplast Membranes of Shade-Tolerant and Light Loving Tradescantia Species
Electron Transport in Chloroplast Membranes of Shade-Tolerant and Light Loving Tradescantia Species
The processes of electronic transport in chloroplasts of two contrasting species of Tradescantia, the shade-tolerant speci...
Effects of Plant Acclimation on Electron Transport in Chloroplast Membranes of Cucumis sativus and Cucumis melo
Effects of Plant Acclimation on Electron Transport in Chloroplast Membranes of Cucumis sativus and Cucumis melo
The processes of electron transport in the leaves of two species of plants of the genus Cucumis, the shade-tolerant specie...
Monoclonal Line of Cells Co-Expressing Genetically Encoded Sensors for cAMP and Ca2+
Monoclonal Line of Cells Co-Expressing Genetically Encoded Sensors for cAMP and Ca2+
A variety of surface receptors and intracellular signaling systems are involved in cell-to-cell communication and paracrin...
Cationic Lipoaminoacid Derivatives of Diethanolamine As Potentially Membrane-Active Antibacterial Agents
Cationic Lipoaminoacid Derivatives of Diethanolamine As Potentially Membrane-Active Antibacterial Agents
This work is aimed to develop several cationic amphiphiles based on amino acid derivatives of diethanolamine as potentiall...
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