Akhtar A., Singh S., Kaushik R., Awasthi R., Behl T. 2024. Types of memory, dementia, Alzheimer’s disease, and their various pathological cascades as targets for potential pharmacological drugs. Ageing Res. Rev. 96, 102289.

Article  CAS  PubMed  Google Scholar 

Gholami A. 2023. Alzheimer’s disease: The role of proteins in formation, mechanisms, and new therapeutic approaches. Neurosci. Lett. 817, 137532.

Article  CAS  PubMed  Google Scholar 

Singh M. K., Shin Y., Ju S., Han S., Kim S.S., Kang I. 2024. Comprehensive overview of Alzheimer’s disease: Etiological insights and degradation strategies. Int. J. Mol. Sci. 25, 6901.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tyagi K., Rai P., Gautam A., Kaur H., Kapoor S., Suttee A., Jaiswal P. K., Sharma A., Singh G., Barnwal R.P. 2023. Neurological manifestations of SARS-CoV-2: Complexity, mechanism and associated disorders. Eur. J. Med. Res. 28, 307.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Swain S.P., Mahanta C.S., Maurya M., Mandal D., Parihar V., Ravichandiran V. 2024. Exploring SK/S1P/S1PR pathway as a target for antiviral drug development. Health Sciences Rev. 11, 100177.

Article  Google Scholar 

Fan C., Wu Y., Rui X., Yang Y., Ling C., Liu S., Liu S., Wang Y. 2022. Animal models for COVID-19: Advances, gaps and perspectives. Signal Transduct. Target. Ther. 7, 220.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Belotserkovskaya Y.G., Romanovskikh A.G., Smirnov I.P., Sinopalnikov, A.I. 2021. Long COVID-19. Consilium Medicum. 23, 261–268.

Article  Google Scholar 

Hu C., Chen C., Dong X.P. 2021. Impact of COVID-19 pandemic on patients with neurodegenerative diseases. Front. Aging Neurosci. 13, 664965.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Pulliam L., Sun B., McCafferty E., Soper S.A., Witek M.A., Hu M., Ford J.M., Song S., Kapogiannis D., Glesby M.J., Merenstein D., Tien P.C., Freasier H., French A., McKay H., Diaz M.M., Ofotokun I., Lake J.E., Margolick J.B., Kim E.-Y., Levine S.R., Fischl M.A., Li W., Martinson J., Tang N. 2024. Microfluidic isolation of neuronal-enriched extracellular vesicles shows distinct and common neurological proteins in long COVID, HIV infection and Alzheimer’s disease. Int. J. Mol. Sci. 25, 3830.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rudnicka-Drożak E., Drożak P., Mizerski G., Zaborowski T., Ślusarska B., Nowicki G., Drożak M. 2023. Links between COVID-19 and Alzheimer’s disease – What do we already know? Int. J. Environ. Res. Public Health. 20, 2146.

Article  PubMed  PubMed Central  Google Scholar 

Griggs E., Trageser K., Naughton S., Yang E.J., Mathew B., Van Hyfte G., Hellmers L., Jette N., Estill M., Shen L., Fischer T., Pasinetti G.M. 2023. Recapitulation of pathophysiological features of AD in SARS-CoV-2-infected subjects. Elife. 12, e86333.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xia X., Wang Y., Zheng J. 2021. COVID-19 and Alzheimer’s disease: How one crisis worsens the other. Transl. Neurodegener. 10, 15.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gkouskou K., Vasilogiannakopoulou T., Andreakos E., Davanos N., Gazouli M., Sanoudou D., Eliopoulos A. G. 2021. COVID-19 enters the expanding network of apolipoprotein E4-related pathologies. Redox Biol. 41, 101938.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kotsev S.V., Miteva., Krayselska S., Shopova M., Pishmisheva-Peleva M., Stanilova S.A., Velikova T. 2021. Hypotheses and facts for genetic factors related to severe COVID-19. World J. Virol. 10, 137.

Article  PubMed  PubMed Central  Google Scholar 

Naughton S.X., Raval U., Pasinetti G.M. 2020. Potential novel role of COVID-19 in Alzheimer’s disease and preventative mitigation strategies. J. Alzheimers Dis. 76, 21–25.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bobkova N.V. 2021. The balance between two branches of RAS can protect us from severe COVID-19 course. Biochem. (Moscow), Suppl. Series A: Membr. Cell Biol. 15, 36–51.

CAS  Google Scholar 

Alenina N., Bader M. 2019. ACE2 in brain physiology and pathophysiology: Evidence from transgenic animal models. Neurochem. Res. 44, 1323–1329.

Article  CAS  PubMed  Google Scholar 

Mahajan S., Sen D., Sunil A., Srikanth P., Marathe S.D., Shaw K., Sahare M., Galande S., Abraham N.M. 2023. Knockout of angiotensin converting enzyme-2 receptor leads to morphological aberrations in rodent olfactory centers and dysfunctions associated with sense of smell. Front. Neurosci. 17, 1180868.

Article  PubMed  PubMed Central  Google Scholar 

Panariello F., Cellini L., Speciani M., De Ronchi D., Atti A. R. 2020. How does SARS-CoV-2 affect the central nervous system? A working hypothesis. Front. Psychiatry. 11, 582345.

Article  PubMed  PubMed Central  Google Scholar 

Saikarthik J., Saraswathi I., Al-Atram A. A. 2022. Does COVID-19 affect adult neurogenesis? A neurochemical perspective. In: Recent advances in neurochemistry. Heinbockel T., Weissert R., Eds. UK: Intechopen, p. 134.

Google Scholar 

Gross L.Z., Sacerdoti M., Piiper A., Zeuzem S., Leroux A. E., Biondi R.M. 2020. ACE2, the receptor that enables infection by SARS-CoV-2: Biochemistry, structure, allostery and evaluation of the potential development of ACE2 modulators. Chem. Med. Chem. 15, 1682–1690.

Article  CAS  PubMed  Google Scholar 

Reveret L., Leclerc M., Emond V., Tremblay C., Loiselle A., Bourassa P., Bennett D.A., Hébert S.S., Calon F. 2023. Higher angiotensin-converting enzyme 2 (ACE2) levels in the brain of individuals with Alzheimer’s disease. Acta Neuropathol. Commun. 11, 159.

Article  PubMed  PubMed Central  Google Scholar 

Komatsu T., Suzuki Y., Imai J., Sugano S., Hida M., Tanigami A., Muroi S., Yamada Y., Hanaoka K. 2002. Molecularcloning, mRNA expression and chromosomal localization of mouse angiotensin-converting enzyme-related carboxypeptidase (mACE2). DNA Sequence. 13, 217–220.

Article  CAS  PubMed  Google Scholar 

Staroverov V., Galatenko A., Knyazev E., Tonevitsky A. 2024. Mathematical model explains differences in Omicron and Delta SARS-CoV-2 dynamics in Caco-2 and Calu-3 cells. Peer J. 12, e16964.

Article  PubMed  PubMed Central  Google Scholar 

Ye M., Wysocki J., Gonzales-Pacheco F.R., Salem M., Evora K., Garcia-Halpin L., Poglitsch M., Schuster M., Batlle D. 2012. Murine recombinant ACE2: Effect on angiotensin II dependent hypertension and distinctive ACE2 inhibitor characteristics on rodent and human ACE2. Hypertension. 60, 730.

Article  CAS  PubMed  Google Scholar 

Clever S., Volz A. 2023. Mouse models in COVID-19 research: Analyzing the adaptive immune response. Med. Microbiol. Immunol. 212, 165–183.

Article  CAS  PubMed  Google Scholar 

Bobkova N.V., Poltavtseva R.A., Samokhin A.N., Sukhikh G.T. 2013. Therapeutic effect of mesenchymal multipotent stromal cells on the memory of animals with neurodegeneration of the Alzheimer type. Kletochnye tekhnologii v biologii i meditsine (Rus.). 3, 123–126.

Bobkova N.V., Lyabin D.N., Medvinskaya N.I., Samokhin A.N., Nekrasov P.V., Nesterova I.V., Aleksandrova I.Y., Tatarnikova O.G., Bobylev A.G., Vikhlyantsev I.M., Kukharsky M.S., Ustyugov A.A., Polyakov D.N., Eliseeva I.A., Kretov D.A., Guryanov S G., Ovchinnikov L.P. 2015. The Y-box binding protein 1 suppresses Alzheimer’s disease progression in two animal models. PLoS One. 10, e0138867.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chaplygina A.V., Zhdanova D.Y., Kovalev V.I., Poltavtseva R.A., Medvinskaya N.I., Bobkova N.V. 2022. Cell therapy as a way to correct impaired neurogenesis in the adult brain in a model of Alzheimer’s disease. J. Evol. Biochem. Physiol. 58, 117–137.

Article  CAS  Google Scholar 

Zhdanova D.Yu., Poltavtseva R.A., Svirschevskaya E.V., Bobkova N.V. 2020. Effect of intranasal administration of exosomes of multipotent mesenchymal stromal cells on memory in mice in the model of Alzheimer’s disease. Kletochnye tekhnologii v biologii i meditsine (Rus.). 4, 289–296.

Oakley H., Cole S.L., Logan S., Maus E., Shao P., Craft J., Vassar R. 2006. Intraneuronal β-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer’s disease mutations: Potential factors in amyloid plaque formation. Eur. J. Neurosci. 26, 10129–10140.

Article  CAS