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Fluorescence lifetime imaging microscopy of endogenous fluorophores in health and disease
Fluorescence lifetime imaging microscopy of endogenous fluorophores in health and disease
Fluorescence Lifetime Imaging Microscopy (FLIM) of endogenous fluorophores has recently emerged as a powerful, marker-free...
Plasticity in leukocyte migration during haematopoiesis and inflammation
Plasticity in leukocyte migration during haematopoiesis and inflammation
Under normal physiological conditions, leukocytes and other tissue resident immune cells have been shown to migrate using ...
The influences of ARHGEF9 on myoblasts migration and differentiation
The influences of ARHGEF9 on myoblasts migration and differentiation
Rho guanine nucleotide exchange factor 9 (ARHGEF9), as a protein that assists small GTPases, is widely present in various ...
RNA-seq and ChIP-seq unveils thyroid hormone receptor α deficiency affects skeletal muscle myoblast proliferation and differentiation via Col6a1 during aging
RNA-seq and ChIP-seq unveils thyroid hormone receptor α deficiency affects skeletal muscle myoblast proliferation and differentiation via Col6a1 during aging
Primary sarcopenia, an age-related syndrome, is a serious threat to the health and longevity of the elderly. Our prior stu...
miR-2400 promotes proliferation of bovine skeletal muscle-derived satellite cells by regulating MAGED1 genes expression
miR-2400 promotes proliferation of bovine skeletal muscle-derived satellite cells by regulating MAGED1 genes expression
microRNAs play a crucial role in the intricate process of muscle satellite cells proliferation and differentiation. Previo...
Insights into human muscle biology from human primary skeletal muscle cell culture
Insights into human muscle biology from human primary skeletal muscle cell culture
This review arises from the symposium held in honour of Prof Jenny Morgan at UCL in 2024 and the authors would like to ack...
The elementary step that generates force and sinusoidal analysis in striated muscle fibers
The elementary step that generates force and sinusoidal analysis in striated muscle fibers
The elementary step that generates force by cross-bridges (CBs) in striated muscles is reviewed. A literature search focus...
Skeletal muscle: a biologists’ adventure playground
Skeletal muscle: a biologists’ adventure playground
A brief discussion about skeletal muscle, aberrant expression of dystrophin from null mutations of the gene, potential exp...
The impact of mitokine MOTS-c administration on the soleus muscle of rats subjected to a 7-day hindlimb suspension
The impact of mitokine MOTS-c administration on the soleus muscle of rats subjected to a 7-day hindlimb suspension
The aim of the study was to investigate the effect of MOTS-c on the key functional alterations in the rat soleus muscle du...
Theoretical treatment of tension transients in muscle following sudden changes in orthophosphate concentration: implications for energy transduction
Theoretical treatment of tension transients in muscle following sudden changes in orthophosphate concentration: implications for energy transduction
The relative timing of the force-generating power stroke and release of the ATP-hydrolysis product orthophosphate (Pi) in ...
Influence of neuromuscular transmission and Na channel inhibitors on strength-duration relationship in isolated slow- and fast-twitch muscles
Influence of neuromuscular transmission and Na channel inhibitors on strength-duration relationship in isolated slow- and fast-twitch muscles
Strength-duration (S-D) relationship reflects muscle excitability which partially determines force production. Isolated mu...
Regulation and function of Pax3 in muscle stem cell heterogeneity and stress response
Regulation and function of Pax3 in muscle stem cell heterogeneity and stress response
Pax3 is a key transcription factor that regulates skeletal muscle development and regeneration and plays a critical role i...
Smooth muscle cells from skin perforator vessels as a new tool for vascular research
Smooth muscle cells from skin perforator vessels as a new tool for vascular research
Vascular smooth muscle cells (SMC) comprise the medial layer of blood vessels and are responsible for maintaining vascular...
Residual force enhancement following hindlimb unloading and exercise prehabilitation
Residual force enhancement following hindlimb unloading and exercise prehabilitation
This study was performed to investigate the effect of exercise prehabilitation (EPH) on passive force, residual force enha...
Myoblast and fibroblast derived small extracellular vesicles differentially affect myoblast migration dynamics
Myoblast and fibroblast derived small extracellular vesicles differentially affect myoblast migration dynamics
Muscle injury activates satellite cells and fibroblasts, with extracellular vesicles (EVs) mediating the related intercell...
Skeletal muscle alterations in Marfan syndrome: a systematic review
Skeletal muscle alterations in Marfan syndrome: a systematic review
Marfan syndrome is an autosomal dominant multisystemic connective tissue disorder caused by mutations in the FBN1 gene. Al...
Danicamtiv affected isometric force and cross-bridge kinetics similarly in skinned myocardial strips from male and female rats
Danicamtiv affected isometric force and cross-bridge kinetics similarly in skinned myocardial strips from male and female rats
Myotropes are pharmaceuticals that have recently been developed or are under investigation for the treatment of heart dise...
Inhibition of the ubiquitin-proteasome system reduces the abundance of pyruvate dehydrogenase kinase 1 in cultured myotubes
Inhibition of the ubiquitin-proteasome system reduces the abundance of pyruvate dehydrogenase kinase 1 in cultured myotubes
Pyruvate dehydrogenase kinase (PDK), which phosphorylates the pyruvate dehydrogenase complex, regulates glucose metabolism...
Biomechanical evaluation of flash-frozen and cryo-sectioned papillary muscle samples by using sinusoidal analysis: cross-bridge kinetics and the effect of partial Ca2+ activation
Biomechanical evaluation of flash-frozen and cryo-sectioned papillary muscle samples by using sinusoidal analysis: cross-bridge kinetics and the effect of partial Ca2+ activation
We examined the integrity of flash-frozen and cryo-sectioned cardiac muscle preparations (introduced by Feng and Jin, 2020...
Unraveling the bidirectional relationship between muscle inflammation and satellite cells activity: influencing factors and insights
Unraveling the bidirectional relationship between muscle inflammation and satellite cells activity: influencing factors and insights
Inflammation stands as a vital and innate function of the immune system, essential for maintaining physiological homeostas...
Muscle spindle receptors and their impact on Parkinson´s disease and Cerebral Palsy subjects
Muscle spindle receptors and their impact on Parkinson´s disease and Cerebral Palsy subjects
In some neurological conditions, like Parkinson’s disease (PD) and Cerebral Palsy (CP), as well as with ageing, musc...
Enduring effects of acute prenatal ischemia in rat soleus muscle, and protective role of erythropoietin
Enduring effects of acute prenatal ischemia in rat soleus muscle, and protective role of erythropoietin
Motor disorders are considered to originate mainly from brain lesions. Placental dysfunction or maternal exposure to a per...
Rbm24-mediated post-transcriptional regulation of skeletal and cardiac muscle development, function and regeneration
Rbm24-mediated post-transcriptional regulation of skeletal and cardiac muscle development, function and regeneration
RNA-binding proteins are critically involved in the post-transcriptional control of gene expression during embryonic devel...
Skeletal muscle of young females under resistance exercise exhibits a unique innate immune cell infiltration profile compared to males and elderly individuals
Skeletal muscle of young females under resistance exercise exhibits a unique innate immune cell infiltration profile compared to males and elderly individuals
Muscle damage resulting from physical activities such as exercise triggers an immune response crucial for tissue repair an...
Methylglyoxal reduces resistance exercise-induced protein synthesis and anabolic signaling in rat tibialis anterior muscle
Methylglyoxal reduces resistance exercise-induced protein synthesis and anabolic signaling in rat tibialis anterior muscle
Resistance exercise provides significant benefits to skeletal muscle, including hypertrophy and metabolic enhancements, su...
ANKRD1 expression is aberrantly upregulated in the mdm mouse model of muscular dystrophy and induced by stretch through NFκB
ANKRD1 expression is aberrantly upregulated in the mdm mouse model of muscular dystrophy and induced by stretch through NFκB
The muscular dystrophy with myositis (mdm) mouse model results in a severe muscular dystrophy due to an 83-amino-acid dele...
The effects of exercise and mitochondrial transplantation alone or in combination against Doxorubicin-induced skeletal muscle atrophy
The effects of exercise and mitochondrial transplantation alone or in combination against Doxorubicin-induced skeletal muscle atrophy
Doxorubicin (DOX) is a chemotherapy drug used to treat various types of cancer, but it is associated with significant side...
Four phases of a force transient emerge from a binary mechanical system
Four phases of a force transient emerge from a binary mechanical system
Accurate models of muscle contraction are important for understanding both muscle performance and the therapeutics that en...
TAM-associated CASQ1 mutants diminish intracellular Ca2+ content and interfere with regulation of SOCE
TAM-associated CASQ1 mutants diminish intracellular Ca2+ content and interfere with regulation of SOCE
Tubular aggregate myopathy (TAM) is a rare myopathy characterized by muscle weakness and myalgia. Muscle fibers from TAM p...
Arginine ingestion inhibits phagocyte invasion in eccentrically contracted rat fast-twitch muscle
Arginine ingestion inhibits phagocyte invasion in eccentrically contracted rat fast-twitch muscle
Eccentric contraction (ECC) has been shown to induce leukocyte invasion into skeletal muscle, resulting in muscle inflamma...
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