Arechavala-Gomeza V, Kinali M, Feng L, Guglieri M, Edge G, Main M et al (2010) Revertant fibres and dystrophin traces in Duchenne muscular dystrophy: implication for clinical trials. Neuromuscul Disord 20(5):295–301

Article  PubMed  Google Scholar 

Beauchamp JR, Heslop L, Yu DS, Tajbakhsh S, Kelly RG, Wernig A et al (2000) Expression of CD34 and Myf5 defines the majority of quiescent adult skeletal muscle satellite cells. J Cell Biol 151(6):1221–1234

Article  CAS  PubMed  PubMed Central  Google Scholar 

Blaveri K, Heslop L, Yu DS, Rosenblatt JD, Gross JG, Partridge TA et al (1999) Patterns of repair of dystrophic mouse muscle: studies on isolated fibers. Dev Dynamics: Official Publication Am Association Anatomists 216(3):244–256

Article  CAS  Google Scholar 

Boldrin L, Morgan JE (2012) Human satellite cells: identification on human muscle fibres. PLoS Curr 3:RRN1294

Article  PubMed  PubMed Central  Google Scholar 

Boldrin L, Morgan JE (2013) Grafting of a single donor myofibre promotes hypertrophy in dystrophic mouse muscle. PLoS ONE 8(1):e54599

Article  CAS  PubMed  PubMed Central  Google Scholar 

Boldrin L, Zammit PS, Morgan JE (2015) Satellite cells from dystrophic muscle retain regenerative capacity. Stem Cell Res 14(1):20–29

Article  CAS  PubMed  PubMed Central  Google Scholar 

Collins CA, Gnocchi VF, White RB, Boldrin L, Perez-Ruiz A, Relaix F et al (2009) Integrated functions of Pax3 and Pax7 in the regulation of proliferation, cell size and myogenic differentiation. PLoS ONE 4(2):e4475

Article  PubMed  PubMed Central  Google Scholar 

Cousins JC, Woodward KJ, Gross JG, Partridge TA, Morgan JE (2004) Regeneration of skeletal muscle from transplanted immortalised myoblasts is oligoclonal. J Cell Sci 117(Pt 15):3259–3269

Article  CAS  PubMed  Google Scholar 

Crawford GE, Lu QL, Partridge TA, Chamberlain JS (2001) Suppression of revertant fibers in Mdx mice by expression of a functional dystrophin. Hum Mol Genet 10(24):2745–2750

Article  CAS  PubMed  Google Scholar 

Crist CG, Montarras D, Pallafacchina G, Rocancourt D, Cumano A, Conway SJ et al (2009) Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression. Proc Natl Acad Sci U S A 106(32):13383–13387

Article  CAS  PubMed  PubMed Central  Google Scholar 

Danko I, Chapman V, Wolff JA (1992) The frequency of revertants in Mdx mouse genetic models for Duchenne muscular dystrophy. Pediatr Res 32(1):128–131

Article  CAS  PubMed  Google Scholar 

Dubowitz VS, Oldfors CA (2013) A. Muscle Biopsy: A Practical Approach. 4th ed: Elsevier; 2013

Dutta D, Nguyen V, Campbell KS, Padron R, Craig R (2023a) Cryo-EM structure of the human cardiac myosin filament. Nature 623(7988):853–862

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dutta D, Nguyen V, Campbell KS, Padron R, Craig R (2023b) Cryo-EM structure of the human cardiac myosin filament. BioRxiv

Fanin M, Danieli G, Cadaldini M, Miorin M, Vitiello L, Angelini C (1995) Dystrophin-posistive fibers in Duchenne dystrophy: origin and correlation to clinical course. MUSCLE NERVE 18:1115–1120

Article  CAS  PubMed  Google Scholar 

Fritz JD, Danko I, Roberds SL, Campbell KP, Latendresse JS, Wolff JA (1995) Expression of deletion-containing dystrophins in Mdx muscle: implications for gene therapy and dystrophin function. Pediatr Res 37(6):693–700

Article  CAS  PubMed  Google Scholar 

Greaser ML, Pleitner JM (2014) Titin isoform size is not correlated with thin filament length in rat skeletal muscle. Front Physiol 5:35

Article  PubMed  PubMed Central  Google Scholar 

Guo W, Bharmal SJ, Esbona K, Greaser ML (2010) Titin diversity–alternative splicing gone wild. J Biomed Biotechnol 2010:753675

Article  PubMed  PubMed Central  Google Scholar 

Guo W, Schafer S, Greaser ML, Radke MH, Liss M, Govindarajan T et al (2012) RBM20, a gene for hereditary cardiomyopathy, regulates Titin splicing. Nat Med 18(5):766–773

Article  CAS  PubMed  PubMed Central  Google Scholar 

Guo W, Zhu C, Yin Z, Wang Q, Sun M, Cao H et al (2018) Splicing factor RBM20 regulates transcriptional network of Titin associated and calcium handling genes in the heart. Int J Biol Sci 14(4):369–380

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hoffman EP, Morgan JE, Watkins SC, Partridge TA (1990) Somatic reversion/suppression of the Mdx mouse phenotype in vivo. J Neurol Sci 99:9–25

Article  CAS  PubMed  Google Scholar 

Klein CJ, Coovert DD, Bulman DE, Ray PN, Mendell JR, Burghes AH (1992) Somatic reversion/suppression in Duchenne muscular dystrophy (DMD): evidence supporting a frame-restoring mechanism in rare dystrophin-positive fibers. Am J Hum Genet 50(5):950–959

CAS  PubMed  PubMed Central  Google Scholar 

Lu QL, Morris GE, Wilton SD, Ly T, Artem’yeva OV, Strong P et al (2000a) Massive idiosyncratic exon skipping corrects the nonsense mutation in dystrophic mouse muscle and produces functional revertant fibers by clonal expansion. J Cell Biol 148(5):985–996

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lu QL, Morris GE, Wilton SD, Ly T, Artem’yeva OV, Strong P et al (2000b) Massive idiosyncratic exon skipping corrects the nonsense mutation in dystrophic mouse muscle and produces functional revertant fibers by clonal expansion. J Cell Biol 148(5):985–995

Article  CAS  PubMed  PubMed Central  Google Scholar 

Morgan J, Partridge T (2020) Skeletal muscle in health and disease. Dis Model Mech. 13(2)

Morgan JE, Hoffman EP, Partridge TA (1990) Normal myogenic cells from newborn mice restore normal histology to degenerating muscles of the Mdx mouse. J Cell Biol 111(6 Pt 1):2437–2449

Article  CAS  PubMed  Google Scholar 

Morin A, Stantzou A, Petrova ON, Hildyard J, Tensorer T, Matouk M et al (2023) Dystrophin myonuclear domain restoration governs treatment efficacy in dystrophic muscle. Proc Natl Acad Sci U S A 120(2):e2206324120

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nicholson LV, Johnson MA, Bushby KM, Gardner Medwin D (1993) Functional significance of dystrophin positive fibres in Duchenne muscular dystrophy. Arch Dis Child 68(5):632–636

Article  CAS  PubMed  PubMed Central  Google Scholar 

Partridge TA, Morgan JE, Coulton GR, Hoffman EP, Kunkel LM (1989) Conversion of Mdx myofibres from dystrophin-negative to -positive by injection of normal myoblasts. Nature 337(6203):176–179

Article  CAS  PubMed  Google Scholar 

Rodrigues M, Echigoya Y, Maruyama R, Lim KR, Fukada SI, Yokota T (2016) Impaired regenerative capacity and lower revertant fibre expansion in dystrophin-deficient Mdx muscles on DBA/2 background. Sci Rep 6:38371

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tamborrini D, Wang Z, Wagner T, Tacke S, Stabrin M, Grange M et al (2023) Structure of the native myosin filament in the relaxed cardiac sarcomere. Nature 623(7988):863–871

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wallgren-Pettersson C, Jasani B, Rosser LG, Lazarou LP, Nicholson LV, Clarke A (1993) Immunohistological evidence for second or somatic mutations as the underlying cause of dystrophin expression by isolated fibres in Xp21 muscular dystrophy of Duchenne-type severity. J Neurol Sci 118(1):56–63

Article  CAS