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Cardiometabolic heart failure with preserved ejection fraction: from molecular signatures to personalized treatment
Cardiometabolic heart failure with preserved ejection fraction: from molecular signatures to personalized treatment
Heart failure with preserved ejection fraction (HFpEF) represents nearly half of all heart failure cases globally. The inc...
Human cardiac tissues produce lower contractile stress and exhibit slower cross-bridge cycling in type 2 diabetes
Human cardiac tissues produce lower contractile stress and exhibit slower cross-bridge cycling in type 2 diabetes
Diabetes mellitus elevates the risk of developing heart failure and increases associated mortality rates. While the clinic...
Efficacy and safety of Tafolecimab in Chinese patients with type 2 diabetes and hypercholesterolemia: a post-hoc analysis of pooled data from three phase 3 trials
Efficacy and safety of Tafolecimab in Chinese patients with type 2 diabetes and hypercholesterolemia: a post-hoc analysis of pooled data from three phase 3 trials
This study evaluated the efficacy and safety of tafolecimab in patients with type 2 diabetes (T2D) and hypercholesterolemi...
Interpretable machine learning analysis of immunoinflammatory biomarkers for predicting CHD among NAFLD patients
Interpretable machine learning analysis of immunoinflammatory biomarkers for predicting CHD among NAFLD patients
Coronary Heart Disease (CHD) and Non-Alcoholic Fatty Liver Disease (NAFLD) share overlapping pathogenic mechanisms includi...
Fatty liver index is an independent risk factor for all-cause mortality and major cardiovascular events in type 1 diabetes: an 11-year observational study
Fatty liver index is an independent risk factor for all-cause mortality and major cardiovascular events in type 1 diabetes: an 11-year observational study
Non-alcoholic fatty liver disease (NAFLD), identified by the Fatty Liver Index (FLI), is associated with increased mortali...
The prognostic value of the stress hyperglycemia ratio for all-cause and cardiovascular mortality in patients with diabetes or prediabetes: insights from NHANES 2005–2018
The prognostic value of the stress hyperglycemia ratio for all-cause and cardiovascular mortality in patients with diabetes or prediabetes: insights from NHANES 2005–2018
The Stress hyperglycemia ratio (SHR) is a novel marker reflecting the true acute hyperglycemia status and is associated wi...
The SGLT2 inhibitor Empagliflozin promotes post-stroke functional recovery in diabetic mice
The SGLT2 inhibitor Empagliflozin promotes post-stroke functional recovery in diabetic mice
Type-2 diabetes (T2D) worsens stroke recovery, amplifying post-stroke disabilities. Currently, there are no therapies targ...
Effects of exenatide on coronary stent’s endothelialization in subjects with type 2 diabetes: a randomized controlled trial. The Rebuild study
Effects of exenatide on coronary stent’s endothelialization in subjects with type 2 diabetes: a randomized controlled trial. The Rebuild study
Subjects with type 2 diabetes (T2D) have a higher risk of in-stent restenosis and stent thrombosis. The activation of the ...
Isthmin-1 (ISM1), a novel adipokine that reflects abdominal adipose tissue distribution in individuals with obesity
Isthmin-1 (ISM1), a novel adipokine that reflects abdominal adipose tissue distribution in individuals with obesity
The assessment of obesity-related health risks has traditionally relied on the Body Mass Index and waist circumference, bu...
Effects of diabetes mellitus and glycemic traits on cardiovascular morpho-functional phenotypes
Effects of diabetes mellitus and glycemic traits on cardiovascular morpho-functional phenotypes
The effects of diabetes on the cardiac and aortic structure and function remain unclear. Detecting and intervening these v...
Impact of stress hyperglycemia ratio, derived from glycated albumin or hemoglobin A1c, on mortality among ST-segment elevation myocardial infarction patients
Impact of stress hyperglycemia ratio, derived from glycated albumin or hemoglobin A1c, on mortality among ST-segment elevation myocardial infarction patients
Stress hyperglycemia ratio (SHR), associated with adverse outcomes in patients with ST-segment elevation myocardial infarc...
An elevated triglyceride-glucose index predicts adverse outcomes and interacts with the treatment strategy in patients with three-vessel disease
An elevated triglyceride-glucose index predicts adverse outcomes and interacts with the treatment strategy in patients with three-vessel disease
Insulin resistance is a pivotal risk factor for cardiovascular diseases, and the triglyceride-glucose (TyG) index is a wel...
Temporal relationship between triglyceride-glucose index and blood pressure and their joint cumulative effect on cardiovascular disease risk: a longitudinal cohort study
Temporal relationship between triglyceride-glucose index and blood pressure and their joint cumulative effect on cardiovascular disease risk: a longitudinal cohort study
Concurrent insulin resistance and elevated blood pressure are commonly observed in cardiovascular disease (CVD) and have l...
Cost-effectiveness of screening of coronary artery disease in patients with type 2 diabetes at a very high cardiovascular risk (SCADIAB) study. Updated study design: emulation of a randomised target trial using electronic health records
Cost-effectiveness of screening of coronary artery disease in patients with type 2 diabetes at a very high cardiovascular risk (SCADIAB) study. Updated study design: emulation of a randomised target trial using electronic health records
Type 2 diabetes mellitus (T2DM) is a substantial health problem with a high clinical and economic burden [1, 2]. Despite a...
Effects of dapagliflozin and dapagliflozin-saxagliptin on erythropoiesis, iron and inflammation markers in patients with type 2 diabetes and chronic kidney disease: data from the DELIGHT trial
Effects of dapagliflozin and dapagliflozin-saxagliptin on erythropoiesis, iron and inflammation markers in patients with type 2 diabetes and chronic kidney disease: data from the DELIGHT trial
This post-hoc analysis of the DELIGHT trial assessed effects of the SGLT2 inhibitor dapagliflozin on iron metabolism and m...
Cost-effectiveness of finerenone in chronic kidney disease associated with type 2 diabetes in The Netherlands
Cost-effectiveness of finerenone in chronic kidney disease associated with type 2 diabetes in The Netherlands
In the Netherlands, more than one million patients have type 2 diabetes (T2D), and approximately 36% of these patients hav...
Safety and efficacy of bempedoic acid: a systematic review and meta-analysis of randomised controlled trials
Safety and efficacy of bempedoic acid: a systematic review and meta-analysis of randomised controlled trials
Bempedoic Acid (BA) is a novel Lipid-Lowering Therapy (LLT). We performed a systematic review and meta-analysis to assess ...
Association between the triglyceride–glucose index and left ventricular global longitudinal strain in patients with coronary heart disease in Jilin Province, China: a cross-sectional study
Association between the triglyceride–glucose index and left ventricular global longitudinal strain in patients with coronary heart disease in Jilin Province, China: a cross-sectional study
This study aimed to investigate the association between the triglyceride–glucose (TyG) index and left ventricular gl...
Association of triglyceride glucose index with all-cause and cardiovascular mortality in the general population
Association of triglyceride glucose index with all-cause and cardiovascular mortality in the general population
The Triglyceride-glucose (TyG) index, a novel indicator of insulin resistance, has been associated with mortality from cor...
Once-weekly glucagon-like peptide-1 receptor agonists vs dipeptidyl peptidase-4 inhibitors: cardiovascular effects in people with diabetes and cardiovascular disease
Once-weekly glucagon-like peptide-1 receptor agonists vs dipeptidyl peptidase-4 inhibitors: cardiovascular effects in people with diabetes and cardiovascular disease
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), which have proven cardiovascular benefits, are recommended in peopl...
Effects of diabetes mellitus on left ventricular function and deformation in patients with restrictive cardiomyopathies: a 3.0T CMR feature tracking study
Effects of diabetes mellitus on left ventricular function and deformation in patients with restrictive cardiomyopathies: a 3.0T CMR feature tracking study
Diabetes mellitus (DM) is the most common metabolic disease worldwide and a major risk factor for adverse cardiovascular e...
Machine learning identification of risk factors for heart failure in patients with diabetes mellitus with metabolic dysfunction associated steatotic liver disease (MASLD): the Silesia Diabetes-Heart Project
Machine learning identification of risk factors for heart failure in patients with diabetes mellitus with metabolic dysfunction associated steatotic liver disease (MASLD): the Silesia Diabetes-Heart Project
Diabetes mellitus (DM), heart failure (HF) and metabolic dysfunction associated steatotic liver disease (MASLD) are overla...
Diabetic microvascular disease in non-classical beds: the hidden impact beyond the retina, the kidney, and the peripheral nerves
Diabetic microvascular disease in non-classical beds: the hidden impact beyond the retina, the kidney, and the peripheral nerves
Diabetes microangiopathy, a hallmark complication of diabetes, is characterised by structural and functional abnormalities...
Relationship between the cumulative exposure to atherogenic index of plasma and ischemic stroke: a retrospective cohort study
Relationship between the cumulative exposure to atherogenic index of plasma and ischemic stroke: a retrospective cohort study
Atherogenic index of plasma (AIP) has been demonstrated as a surrogate marker for ischemic stroke, but there is limited ev...
Sodium-glucose cotransporter-2 inhibition for heart failure with preserved ejection fraction and chronic kidney disease with or without type 2 diabetes mellitus: a narrative review
Sodium-glucose cotransporter-2 inhibition for heart failure with preserved ejection fraction and chronic kidney disease with or without type 2 diabetes mellitus: a narrative review
Heart failure (HF), chronic kidney disease (CKD), and type 2 diabetes mellitus (T2DM) are common and interrelated conditio...
Association of glycemic variability with death and severe consciousness disturbance among critically ill patients with cerebrovascular disease: analysis of the MIMIC-IV database
Association of glycemic variability with death and severe consciousness disturbance among critically ill patients with cerebrovascular disease: analysis of the MIMIC-IV database
The association of glycemic variability with severe consciousness disturbance and in-hospital all-cause mortality in criti...
Association between triglyceride glucose-body mass and one-year all-cause mortality of patients with heart failure: a retrospective study utilizing the MIMIC-IV database
Association between triglyceride glucose-body mass and one-year all-cause mortality of patients with heart failure: a retrospective study utilizing the MIMIC-IV database
The triglyceride glucose-body mass (TyG-BMI) index is acknowledged as both a reliable indicator of the risk of cardiovascu...
Triglycerides/HDL cholesterol ratio and type 2 diabetes incidence: Panasonic Cohort Study 10
Triglycerides/HDL cholesterol ratio and type 2 diabetes incidence: Panasonic Cohort Study 10
Previous studies have investigated the association between the ratio of triglycerides (TG) to high-density lipoprotein cho...
Association between triglyceride-glucose index and in-hospital mortality in critically ill patients with sepsis: analysis of the MIMIC-IV database
Association between triglyceride-glucose index and in-hospital mortality in critically ill patients with sepsis: analysis of the MIMIC-IV database
This study aimed to explore the association between the triglyceride-glucose (TyG) index and the risk of in-hospital morta...
Association between insulin resistance and uncontrolled hypertension and arterial stiffness among US adults: a population-based study
Association between insulin resistance and uncontrolled hypertension and arterial stiffness among US adults: a population-based study
Prior research has established the correlation between insulin resistance (IR) and hypertension. While the association bet...
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