Shahim B, Kapelios CJ, Savarese G, Lund LH. Global Public Health Burden of Heart Failure: an updated review. Card Fail Rev. 2023;9:e11.

Article  PubMed  PubMed Central  Google Scholar 

Kannel WB, Hjortland M, Castelli WP. Role of Diabetes in Congestive Heart Failure: the Framingham study. Am J Cardiol. 1974;34(1):29–34.

Article  CAS  PubMed  Google Scholar 

Erqou S, Adler AI, Challa AA, Fonarow GC, Echouffo-Tcheugui JB. Insulin resistance and incident Heart Failure: a meta-analysis. Eur J Heart Fail. 2022;24(6):1139–41.

Article  PubMed  Google Scholar 

Braunwald E. Diabetocardiology: a new subspecialty? Eur Heart J 2023.

Tao LC, Xu JN, Wang TT, Hua F, Li JJ. Triglyceride-glucose index as a marker in Cardiovascular Diseases: landscape and limitations. Cardiovasc Diabetol. 2022;21(1):68.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Minh HV, Tien HA, Sinh CT, Thang DC, Chen CH, Tay JC, Siddique S, Wang TD, Sogunuru GP, Chia YC, et al. Assessment of preferred methods to measure insulin resistance in Asian patients with Hypertension. J Clin Hypertens. 2021;23(3):529–37.

Article  CAS  Google Scholar 

Simental-Mendia LE, Rodriguez-Moran M, Guerrero-Romero F. The product of fasting glucose and triglycerides as surrogate for identifying insulin resistance in apparently healthy subjects. Metab Syndr Relat D. 2008;6(4):299–304.

Article  CAS  Google Scholar 

Placzkowska S, Pawlik-Sobecka L, Kokot I, Piwowar A. Indirect insulin resistance detection: current clinical trends and laboratory limitations. Biomed Pap. 2019;163(3):187–99.

Article  Google Scholar 

Bala C, Gheorghe-Fronea O, Pop D, Pop C, Caloian B, Comsa H, Bozan C, Matei C, Dorobantu M. The Association between six surrogate insulin resistance indexes and Hypertension: a Population-based study. Metab Syndr Relat D. 2019;17(6):328–33.

Article  CAS  Google Scholar 

Ramirez-Velez R, Perez-Sousa MA, Gonzalez-Ruiz K, Cano-Gutierrez CA, Schmidt-RioValle J, Correa-Rodriguez M, Izquierdo M, Romero-Garcia JA, Campos-Rodriguez AY, Triana-Reina HR et al. Obesity- and Lipid-Related Parameters in the Identification of Older Adults with a High Risk of Prediabetes According to the American Diabetes Association: An Analysis of the 2015 Health, Well-Being, and Aging Study. Nutrients 2019, 11(11).

Er LK, Wu S, Chou HH, Hsu LA, Teng MS, Sun YC, Ko YL. Triglyceride glucose-body Mass Index is a simple and clinically useful surrogate marker for insulin resistance in nondiabetic individuals. PLoS One. 2016;11(3):e149731.

Article  Google Scholar 

Lim J, Kim J, Koo SH, Kwon GC. Comparison of triglyceride glucose index, and related parameters to predict insulin resistance in Korean adults: an analysis of the 2007–2010 Korean National Health and Nutrition Examination Survey. PLoS One. 2019;14(3):e212963.

Article  Google Scholar 

Zhang Y, Wang R, Fu X, Song H. Non-insulin-based insulin resistance indexes in predicting severity for coronary artery Disease. Diabetol Metab Syndr. 2022;14(1):191.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cheng W, Kong F, Chen S. Comparison of the predictive value of four insulin resistance surrogates for the prevalence of Hypertension: a population-based study. Diabetol Metab Syndr. 2022;14(1):137.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li H, Shi Z, Chen X, Wang J, Ding J, Geng S, Sheng X, Shi S. Relationship between six insulin resistance surrogates and nonalcoholic fatty Liver Disease among older adults: a cross-sectional study. Diabet Metab Synd Ob. 2023;16:1685–96.

Article  CAS  Google Scholar 

Han Y, Hu H, Li Q, Deng Z, Liu D. Triglyceride glucose-body mass index and the risk of progression to Diabetes from prediabetes: a 5-year cohort study in Chinese adults. Front Public Health. 2023;11:1028461.

Article  PubMed  PubMed Central  Google Scholar 

Johnson A, Bulgarelli L, Shen L, Gayles A, Shammout A, Horng S, Pollard TJ, Hao S, Moody B, Gow B, et al. MIMIC-IV, a freely accessible electronic health record dataset. Sci Data. 2023;10(1):1.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cheng Y, Fang Z, Zhang X, Wen Y, Lu J, He S, Xu B. Association between triglyceride glucose-body mass index and cardiovascular outcomes in patients undergoing percutaneous coronary intervention: a retrospective study. Cardiovasc Diabetol. 2023;22(1):75.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Stekhoven DJ, Buhlmann P. MissForest–non-parametric missing value imputation for mixed-type data. Bioinformatics. 2012;28(1):112–8.

Article  CAS  PubMed  Google Scholar 

Ingelsson E, Sundstrom J, Arnlov J, Zethelius B, Lind L. Insulin resistance and risk of Congestive Heart Failure. Jama-J Am Med Assoc. 2005;294(3):334–41.

Article  CAS  Google Scholar 

Held C, Gerstein HC, Yusuf S, Zhao F, Hilbrich L, Anderson C, Sleight P, Teo K. Glucose levels predict hospitalization for Congestive Heart Failure in patients at high cardiovascular risk. Circulation. 2007;115(11):1371–5.

Article  CAS  PubMed  Google Scholar 

How OJ, Aasum E, Severson DL, Chan WY, Essop MF, Larsen TS. Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice. Diabetes. 2006;55(2):466–73.

Article  CAS  PubMed  Google Scholar 

Lebeche D, Davidoff AJ, Hajjar RJ. Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy. Nat Clin Pract Cardiovasc Med. 2008;5(11):715–24.

Article  CAS  PubMed  Google Scholar 

Nagoshi T, Yoshimura M, Rosano GM, Lopaschuk GD, Mochizuki S. Optimization of cardiac metabolism in Heart Failure. Curr Pharm Design. 2011;17(35):3846–53.

Article  CAS  Google Scholar 

Tuunanen H, Knuuti J. Metabolic remodelling in human Heart Failure. Cardiovasc Res. 2011;90(2):251–7.

Article  CAS  PubMed  Google Scholar 

Falcao-Pires I, Leite-Moreira AF. Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment. Heart Fail Rev. 2012;17(3):325–44.

Article  CAS  PubMed  Google Scholar 

Bell DS. Functional class in patients with Heart Failure is associated with the development of Diabetes. Am J Med. 2003;115(5):412.

Article  PubMed  Google Scholar 

Mamas MA, Deaton C, Rutter MK, Yuille M, Williams SG, Ray SG, New J, Gibson JM, Neyses L. Impaired glucose tolerance and insulin resistance in Heart Failure: underrecognized and undertreated? J Card Fail. 2010;16(9):761–8.

Article  CAS  PubMed  Google Scholar 

Heck PM, Dutka DP. Insulin resistance and Heart Failure. Curr Heart Fail Rep. 2009;6(2):89–94.

Article  CAS  PubMed  Google Scholar 

Putnam K, Shoemaker R, Yiannikouris F, Cassis LA. The renin-angiotensin system: a target of and contributor to dyslipidemias, altered glucose homeostasis, and Hypertension of the metabolic syndrome. Am J Physiol-Heart C. 2012;302(6):H1219–30.

Article  CAS  Google Scholar 

Lastra G, Dhuper S, Johnson MS, Sowers JR. Salt, aldosterone, and insulin resistance: impact on the cardiovascular system. Nat Rev Cardiol. 2010;7(10):577–84.

Article  CAS  PubMed  Google Scholar 

Zheng H, Chen G, Wu K, Wu W, Huang Z, Wang X, Chen Z, Cai Z, Cai Z, Lan Y, et al. Relationship between cumulative exposure to triglyceride-glucose index and Heart Failure: a prospective cohort study. Cardiovasc Diabetol. 2023;22(1):239.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khalaji A, Behnoush AH, Khanmohammadi S, Ghanbari MK, Sharifkashani S, Sahebkar A, Vinciguerra C, Cannavo A. Triglyceride-glucose index and Heart Failure: a systematic review and meta-analysis. Cardiovasc Diabetol. 2023;22(1):244.

Article  PubMed  PubMed Central  Google Scholar 

Zhou Q, Yang J, Tang H, Guo Z, Dong W, Wang Y, Meng X, Zhang K, Wang W, Shao C, et al. High triglyceride-glucose (TyG) index is associated with poor prognosis of Heart Failure with preserved ejection fraction. Cardiovasc Diabetol. 2023;22(1):263.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Lavie CJ, Kokkinos P, Lin GM. Obesity paradox is still alive in heart failure. Heart 2023.

Horwich TB, Fonarow GC, Clark AL. Obesity and the obesity Paradox in Heart Failure. Prog Cardiovasc Dis. 2018;61(2):151–6.

Article  PubMed  Google Scholar 

Lavie CJ, Sharma A, Alpert MA, De Schutter A, Lopez-Jimenez F, Milani RV, Ventura HO. Update on obesity and obesity Paradox in Heart Failure. Prog Cardiovasc Dis. 2016;58(4):393–400.

Article  PubMed  Google Scholar 

Fonarow GC, Srikanthan P, Costanzo MR, Cintron GB, Lopatin M. An obesity paradox in acute Heart Failure: analysis of body mass index and inhospital mortality for 108,927 patients in the Acute Decompensated Heart Failure National Registry. Am Heart J. 2007;153(1):74–81.

Article  PubMed  Google Scholar 

Sharma A, Lavie CJ, Borer JS, Vallakati A, Goel S, Lopez-Jimenez F, Arbab-Zadeh A, Mukherjee D, Lazar JM. Meta-analysis of the relation of body mass index to all-cause and cardiovascular mortality and hospitalization in patients with chronic Heart Failure. Am J Cardiol. 2015;115(10):1428–34.

Article  PubMed  Google Scholar