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Amino acid patterns predict white matter integrity measures in the brain in patients across the Alzheimer’s disease continuum
Amino acid patterns predict white matter integrity measures in the brain in patients across the Alzheimer’s disease continuum
Alzheimer’s disease (AD), the leading cause of dementia, poses a growing global health challenge due to its rising p...
Cola acuminata extract’s inhibition of NLRP3 inflammasome in THP-1 cells as a potential treatment option for Parkinson’s disease
Cola acuminata extract’s inhibition of NLRP3 inflammasome in THP-1 cells as a potential treatment option for Parkinson’s disease
Neuroinflammation has been described as one of the multiple clinical manifestations of Parkinson’s and AlzheimerR...
Rice bran extract attenuates cognitive impairment by enhancing pancreatic β-cell insulin secretion in STZ-induced diabetic rats targeting the PPARγ/PDX1 pathway
Rice bran extract attenuates cognitive impairment by enhancing pancreatic β-cell insulin secretion in STZ-induced diabetic rats targeting the PPARγ/PDX1 pathway
Type I diabetes (T1D), also known as juvenile diabetes, is an autoimmune disease that causes gradual destruction of pancre...
Metabolomic analysis of blood spots in a Chinese cohort with autism spectrum disorders: a pilot study
Metabolomic analysis of blood spots in a Chinese cohort with autism spectrum disorders: a pilot study
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with a strong genetic component that is becoming increasin...
Differential effects of industrial and ruminant trans fatty acids on appetitive memory
Differential effects of industrial and ruminant trans fatty acids on appetitive memory
Trans-fatty acids (TFAs) are categorized into industrial TFAs (iTFAs) and ruminant TFAs (rTFAs). TFAs intakes over 48&...
Tanshinone IIA inhibits neuronal ferroptosis and relieves cerebral ischemia‒reperfusion injury by regulating miR-449a/ACSL4
Tanshinone IIA inhibits neuronal ferroptosis and relieves cerebral ischemia‒reperfusion injury by regulating miR-449a/ACSL4
Cerebral ischemia‒reperfusion injury (CI/RI) plays a significant role in the initiation of ischemic stroke. This stu...
An analysis of the therapeutic efficacy and underlying mechanisms of combining lycopene with dental pulp stem cells to ameliorate alzheimer’s disease in rats
An analysis of the therapeutic efficacy and underlying mechanisms of combining lycopene with dental pulp stem cells to ameliorate alzheimer’s disease in rats
The choroid plexus (CP), which is responsible for forming the blood-cerebrospinal fluid barrier, contributes to the modula...
Ivermectin’s neuroprotective effects decrease with prolonged use after cerebral ischemia/reperfusion
Ivermectin’s neuroprotective effects decrease with prolonged use after cerebral ischemia/reperfusion
Ivermectin (IVM), the recipient of the 2015 Nobel Prize, is an FDA-approved drug for a variety of parasitic diseases in an...
Association between traumatic brain injury and risk of developing infections in the central nervous system and periphery
Association between traumatic brain injury and risk of developing infections in the central nervous system and periphery
Traumatic brain injury (TBI) is defined as structural damage or physiological disruption of brain function resulting from ...
Mechanisms of SIRT1/SIRT3-mediated reduction of mitochondrial regeneration and inflammatory response in diabetic cerebral ischemia-reperfusion injury
Mechanisms of SIRT1/SIRT3-mediated reduction of mitochondrial regeneration and inflammatory response in diabetic cerebral ischemia-reperfusion injury
This study investigates the specific mechanisms by which SIRT1/SIRT3 modulates the reduction of mitochondrial regeneration...
Neuroprotective efficacy of in Cadmium-induced neurotoxicity: involvement of antioxidant defense, anti-inflammatory, dopaminergic, and cholinergic systems
Neuroprotective efficacy of in Cadmium-induced neurotoxicity: involvement of antioxidant defense, anti-inflammatory, dopaminergic, and cholinergic systems
The incidence of neurotoxicity has been rising recently due to increase exposure to toxic compounds such as Cadmium (Cd). ...
Mechanistic study of butylphthalide in alleviating cerebral Edema after intracerebral Hemorrhage by regulating miR-7-5p expression
Mechanistic study of butylphthalide in alleviating cerebral Edema after intracerebral Hemorrhage by regulating miR-7-5p expression
To investigate the mechanisms by which butylphthalide (NBP) alleviates cerebral edema after intracerebral hemorrhage (ICH)...
Neuroprotective effects of Simvastatin against alcohol-induced oxidative stress and neurodegeneration in the Hippocampus of adolescent mice
Neuroprotective effects of Simvastatin against alcohol-induced oxidative stress and neurodegeneration in the Hippocampus of adolescent mice
Adolescent alcohol abuse in disadvantaged communities is a significant concern due to regulatory gaps. It disrupts brain d...
From nonalcoholic fatty liver disease to neuroinflammation: the role of chronic systemic inflammation
From nonalcoholic fatty liver disease to neuroinflammation: the role of chronic systemic inflammation
Neuroinflammation is a significant contributor to neurological disorders. While previous research has mainly concentrated ...
Paeoniflorin and depression: a comprehensive review of underlying molecular mechanisms
Paeoniflorin and depression: a comprehensive review of underlying molecular mechanisms
Depression is one of the common mental disorders that often leads to persistent low mood, feelings of sadness or a sense o...
Exploration of Imatinib involved in amyloidogenesis as a common foundation for type-2 diabetes mellitus (T2DM) and Alzheimer’s disease (AD)
Exploration of Imatinib involved in amyloidogenesis as a common foundation for type-2 diabetes mellitus (T2DM) and Alzheimer’s disease (AD)
Diabetes patients have reduced basal cognitive abilities like learning, memory, and perceptual quickness, as well as a 65 ...
Optimizing predictive biomarkers for alzheimer’s disease: muscarinic M1 antagonist-induced synaptic signaling disruptions and bee venom intervention through cholinergic modulation and multiregression dose selection
Optimizing predictive biomarkers for alzheimer’s disease: muscarinic M1 antagonist-induced synaptic signaling disruptions and bee venom intervention through cholinergic modulation and multiregression dose selection
Alzheimer’s (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and neurochemical im...
Correction to: Non-invasive remote ischemic postconditioning stimulates neurogenesis during the recovery phase after cerebral ischemia
Correction to: Non-invasive remote ischemic postconditioning stimulates neurogenesis during the recovery phase after cerebral ischemia
Cite this articleHuang, D., Liu, H., Qu, Y. et al. Correction to: Non-invasive remote ischemic postconditioning stimulates...
The evaluation of maternal immune activation and the development of schizophrenia in offspring of rats
The evaluation of maternal immune activation and the development of schizophrenia in offspring of rats
Prenatal infection, consequently, maternal immune activation (MIA) contributes to changes in neurogenesis and myelination ...
Neuroprotective effects of resveratrol and sodium valproate in penicillin-induced epilepsy model
Neuroprotective effects of resveratrol and sodium valproate in penicillin-induced epilepsy model
This study investigated resveratrol’s (RSV) neuroprotective properties in a penicillin-mediated epilepsy model, focu...
CD47 signaling induces hepatic cell death and microglia activation during hepatic encephalopathy
CD47 signaling induces hepatic cell death and microglia activation during hepatic encephalopathy
Acute liver failure results from severe hepatic injury and can lead to neurological dysfunction known as hepatic encephalo...
Value of systemic inflammation markers for the detection of minimal and prediction of overt hepatic encephalopathy after TIPS insertion
Value of systemic inflammation markers for the detection of minimal and prediction of overt hepatic encephalopathy after TIPS insertion
Development of overt hepatic encephalopathy (oHE) is a particularly feared complication when considering treatment with tr...
Effects of ginger root extract on cognitive impairment and the Nrf2/GPX4/SLC7A11 signaling pathway in aluminum-exposed rats
Effects of ginger root extract on cognitive impairment and the Nrf2/GPX4/SLC7A11 signaling pathway in aluminum-exposed rats
Aluminum exposure has been widely demonstrated to cause cognitive impairment and neuronal damage, which are significant fa...
Macaiba palm pulp (Acrocomia intumescens Drude) improves memory and induces anxiolytic-like behavior in dyslipidemic rats
Macaiba palm pulp (Acrocomia intumescens Drude) improves memory and induces anxiolytic-like behavior in dyslipidemic rats
Macaiba pulp is a source of bioactive compounds. This study aimed to evaluate the effects of macaiba pulp on anxiety behav...
Regulation of the blood-brain barrier function by peripheral cues in health and disease
Regulation of the blood-brain barrier function by peripheral cues in health and disease
The blood-brain barrier (BBB) is formed by microvascular endothelial cells which are ensembled with pericytes, astrocytes,...
Exploring role of citrus fruits in comorbid neurodegenerative disorders associated with psoriasis
Exploring role of citrus fruits in comorbid neurodegenerative disorders associated with psoriasis
A neurodegenerative illness is a disorder in which the brain and/or spinal cord’s neurons, or nerve cells, gradually...
Intricate mechanism of anxiety disorder, recognizing the potential role of gut microbiota and therapeutic interventions
Intricate mechanism of anxiety disorder, recognizing the potential role of gut microbiota and therapeutic interventions
Anxiety is a widespread psychological disorder affecting both humans and animals. It is a typical stress reaction; however...
Therapeutic potential of the extract of giant millipede Telodeinopus Canaliculatus on epileptogenesis and associated anxiety-like behavior
Therapeutic potential of the extract of giant millipede Telodeinopus Canaliculatus on epileptogenesis and associated anxiety-like behavior
The secretions of Telodeinopus canaliculatus, a giant millipede, are used in traditional medicine to treat epileptic seizu...
Assessment of blood-brain barrier injury in hypertensive CSVD by 11.7TMR T1mapping and microvascular pathologic changes
Assessment of blood-brain barrier injury in hypertensive CSVD by 11.7TMR T1mapping and microvascular pathologic changes
We used spontaneously hypertensive rats (SHR) as a hypertensive cerebral small vessel disease (CSVD) model to quantify blo...
Energy restriction inhibits β-catenin ubiquitination to improve ischemic stroke injury via USP18/SKP2 axis
Energy restriction inhibits β-catenin ubiquitination to improve ischemic stroke injury via USP18/SKP2 axis
Ischemic stroke (IS) remains a global health issue because of its great disability and mortality. Energy restriction (ER) ...
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