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Oblique-incidence reflectivity difference technology identifies the antiviral drug Ribavirin as an inhibitor of lung tumor progression by targeting AMPK signaling
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Real-time visualization of drug-target interactions in native subcellular microenvironments for lysosome-targeted drug discovery
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Molecular mechanisms and therapeutic advances of ferroptosis in radiotherapy resistance of nasopharyngeal carcinoma
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Probucol inhibits palmitic acid-mediated renal calcium oxalate stone formation by targeting KLF5-PPARγ axis-mediated lipotoxicity
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Discovery of Mitochondrial Modulators Using Target-Aggregated Machine Learning
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Pharmacomultiomics suggests new off-targets for targeted anti-cancer agents
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Recent advances in bacterial detection techniques targeting genetic, protein, and enzymatic biomarkers
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Classification of pulmonary inflammation stages and assessment of multicomponent drug intervention based on spatiotemporal imaging variations utilizing RhB-conjugated poly-L-lysine nanoparticles
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Harnessing natural products to target programmed cell death for intervertebral disc degeneration: Mechanisms and opportunity
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A Nanotechnology-Enhanced SERS Platform Integrated with Isothermal Amplification for Ultrasensitive Detection of Urinary miR-21 in Early Acute Kidney Injury Diagnosis
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TCM-Agent: Advancing Network Pharmacology and Herbal Medicine Discovery with LLM-Based Multi-Agent Systems
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Active peptides pursuit from complicated matrices via tracing ligand-protein complex with MS/MS: Chaperone screening for lysozyme as a pilot study
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The dual faces of lactylation: From post-translational modification to disease regulation
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Multi-omics uncovers the critical role of ceramide-mediated Acinetobacter growth suppression in pressure injury healing under aging and malnutrition
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Self-amplifying nicotinamide N-methyltransferase feedback loops: Drivers of anticancer drug resistance and therapeutic opportunities
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NAT10 aggravates psoriasis by promoting keratinocytes fatty acid synthesis via stable FASN transcription
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Microsphere-loaded dual-response in situ gel for enhanced ocular drug delivery
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Identification of lotus seeds stored over different periods by analyzing the changes in the chemical structure of starch
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Unraveling the mechanism of Lianqiaobaidu powder in viral myocarditis: Complementary actions within cardiac cell types
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Integrating mass spectrometry imaging and data-driven segmentation for spatial metabolic mapping of diabetic eye disease
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The anti-hyperuricemia potential of bioactive natural products and extracts derived from traditional Chinese medicines: A review and perspective
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GPCRs identified on mitochondrial membranes: New therapeutic targets for diseases
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Aldolase A accelerates hepatocarcinogenesis by refactoring c-Jun transcription
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Ginkgolic acid inhibits CD8+ T cell activation and induces ferroptosis by lactate dehydrogenase A to exert immunosuppressive effect
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PU.1 regulation of type 1 dendritic cell function via NF-κB pathway in inhibition of non-small cell lung cancer progression
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Silent or low expression of blaTEM and blaSHV suggests potential for targeted proteomics in clinical detection of β-lactamase-related antimicrobial resistance
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ToxBERT: An explainable AI framework for enhancing prediction of adverse drug reactions and structural insights
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Recent trends in mesoporous carbon-based nanoplatforms for biomedical application
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FPS_P/N: A two-dimensional mass spectrometry utilization program with precursor ion determination for accurately distinguishing anthocyanin from other flavonoids
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Fast-Adapting Graph Neural Network with Prior Knowledge for Drug Response Prediction Across Preclinical and Clinical Data
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