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FDA approves anti-prekallikrein drug for hereditary angioedema
FDA approves anti-prekallikrein drug for hereditary angioedema
Discover the world’s best science and medicine | Nature.com
Synthetic lethality in cancer drug discovery: challenges and opportunities
Synthetic lethality in cancer drug discovery: challenges and opportunities
Synthetic lethality, first proposed more than two decades ago, has long held immense promise for targeted cancer therapy. ...
Breakthrough therapy designations in China and the United States
Breakthrough therapy designations in China and the United States
Discover the world’s best science and medicine | Nature.com
New US$3.1 billion foundation takes big, long-term bets on bioscience, AI and the environment
New US$3.1 billion foundation takes big, long-term bets on bioscience, AI and the environment
Lynda Stuart, president and CEO of the newly launched Fund for Science and Technology, discusses the philanthropic organiz...
Microsystem technologies for accelerating the discovery and translation of immunotherapies
Microsystem technologies for accelerating the discovery and translation of immunotherapies
Immunotherapies have transformed the treatment of many cancers and autoimmune diseases. However, durable therapeutic benef...
Upcoming FDA approval decisions in Q4 2025
Upcoming FDA approval decisions in Q4 2025
Discover the world’s best science and medicine | Nature.com
RNA modification systems as therapeutic targets
RNA modification systems as therapeutic targets
Ribonucleotide bases can be chemically modified by cellular enzymes such as methyltransferases to regulate RNA metabolism ...
FDA approves new non-opioid pain drug
Discover the world’s best science and medicine | Nature.com
The multiple myeloma drug market
The multiple myeloma drug market
Discover the world’s best science and medicine | Nature.com
Novel strategies to manage CAR-T cell toxicity
Novel strategies to manage CAR-T cell toxicity
The immune-related adverse events associated with chimeric antigen receptor (CAR)-T cell therapy result in substa...
Voltage-gated sodium channels in excitable cells as drug targets
Voltage-gated sodium channels in excitable cells as drug targets
Excitable cells — including neurons, muscle cells and cardiac myocytes — are unique in expressing high densiti...
Integrating QSAR modelling and deep learning in drug discovery: the emergence of deep QSAR
Integrating QSAR modelling and deep learning in drug discovery: the emergence of deep QSAR
Quantitative structure–activity relationship (QSAR) modelling, an approach that was introduced 60 years ago, is wide...
Extracellular targeted protein degradation: an emerging modality for drug discovery
Extracellular targeted protein degradation: an emerging modality for drug discovery
Targeted protein degradation (TPD) has emerged in the past decade as a major new drug modality to remove intracellular pro...
Top product forecasts for 2024
Discover the world’s best science and medicine | Nature.com
Upcoming market catalysts in Q1 2024
Upcoming market catalysts in Q1 2024
Discover the world’s best science and medicine | Nature.com
FDA approves first chikungunya vaccine
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PROTAC in clinic for autoimmune skin disease
PROTAC in clinic for autoimmune skin disease
Discover the world’s best science and medicine | Nature.com
Gene therapy zeroes in on Parkinson disease brain circuits
Gene therapy zeroes in on Parkinson disease brain circuits
Discover the world’s best science and medicine | Nature.com
FDA approves first-in-class AKT inhibitor
Discover the world’s best science and medicine | Nature.com
A decade of HCV drugs
A decade of HCV drugs
Discover the world’s best science and medicine | Nature.com
Antibodies achieve leptin balancing act
Antibodies achieve leptin balancing act
Discover the world’s best science and medicine | Nature.com
γ-secretase inhibitor notches first approval
Discover the world’s best science and medicine | Nature.com
De-risking rare disease acquisitions: a win–win–win for patients, biotech and investors
Discover the world’s best science and medicine | Nature.com
tRNA therapeutics for genetic diseases
tRNA therapeutics for genetic diseases
Transfer RNAs (tRNAs) have a crucial role in protein synthesis, and in recent years, their therapeutic potential for the t...
CAAR T cells to treat encephalitis
Discover the world’s best science and medicine | Nature.com
A safer polyene antifungal
Discover the world’s best science and medicine | Nature.com
USP30 inhibition protects dopaminergic neurons
Discover the world’s best science and medicine | Nature.com
Open-science drug discovery for COVID-19
Discover the world’s best science and medicine | Nature.com
Antibodies combat Gram-negative pathogen
Antibodies combat Gram-negative pathogen
Discover the world’s best science and medicine | Nature.com
Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets
Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets
Diseases associated with chronic inflammation constitute a major health burden across the world. As central instigators of...
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