SCI Abstract

search
+
Pharmacologic Management of Heart Failure with Preserved Ejection Fraction (HFpEF) in Older Adults
Pharmacologic Management of Heart Failure with Preserved Ejection Fraction (HFpEF) in Older Adults
There are several pharmacologic agents that have been touted as guideline-directed medical therapy for heart failure with ...
How Should Clinicians Discuss Deprescribing with Caregivers of Older Adults Living with Dementia? A Qualitative Study
How Should Clinicians Discuss Deprescribing with Caregivers of Older Adults Living with Dementia? A Qualitative Study
Preventive medications are potential targets for deprescribing in older adults with dementia as goals of care change from ...
An Educational Intervention to Promote Central Nervous System-Active Deprescribing in Dementia: A Pilot Study
An Educational Intervention to Promote Central Nervous System-Active Deprescribing in Dementia: A Pilot Study
Central nervous system (CNS)-active polypharmacy (defined as concurrent exposure to three or more antidepressant, antipsyc...
Psychotropic Polypharmacy in Dementia: A Retrospective Analysis for People with Neuropsychiatric Symptoms Referred to an Australian Dementia Support Service
Psychotropic Polypharmacy in Dementia: A Retrospective Analysis for People with Neuropsychiatric Symptoms Referred to an Australian Dementia Support Service
Despite their limited benefits and serious adverse effects, psychotropics remain frequently prescribed for neuropsychiatri...
Regular Use of Oral Nonsteroidal Anti-inflammatory Drugs in a Population of Polish Seniors: Findings from the PolSenior2 Cross-Sectional Survey
Regular Use of Oral Nonsteroidal Anti-inflammatory Drugs in a Population of Polish Seniors: Findings from the PolSenior2 Cross-Sectional Survey
Older adults represent a growing proportion of the general population. Nonsteroidal anti-inflammatory drugs (NSAIDs) const...
Perioperative Anticholinergic Medication Use and Incident Dementia among Older Surgical Patients: a Retrospective Cohort Study using Real-World Data
Perioperative Anticholinergic Medication Use and Incident Dementia among Older Surgical Patients: a Retrospective Cohort Study using Real-World Data
Inpatient anticholinergic medications have been associated with a higher likelihood of postoperative delirium in older adu...
Safety Study of Anticoagulants for Preventing Deep Venous Thrombosis after Intracerebral Hemorrhage: Data from the Chinese Stroke Center Alliance
Safety Study of Anticoagulants for Preventing Deep Venous Thrombosis after Intracerebral Hemorrhage: Data from the Chinese Stroke Center Alliance
The use of anticoagulants to prevent deep vein thrombosis (DVT) after intracerebral hemorrhage (ICH) remains controversial...
Unveiling Cognitive Impairment in Older Adults with Cancer on Systemic Anticancer Therapy: A Comprehensive Review
Unveiling Cognitive Impairment in Older Adults with Cancer on Systemic Anticancer Therapy: A Comprehensive Review
Cancer-related cognitive impairment significantly affects cancer management and decision-making. While the exact mechanism...
Antidepressants to Manage Osteoarthritic Pain: The Value of Pain Phenotyping
Antidepressants to Manage Osteoarthritic Pain: The Value of Pain Phenotyping
Osteoarthritis (OA) is a chronic condition in which pain significantly affects quality of life, often leading to reduced p...
Factors Influencing General Practitioners’ Deprescribing Decisions for Older Adults, with Insights into Frailty: a Qualitative Study in Greek Primary Care
Factors Influencing General Practitioners’ Deprescribing Decisions for Older Adults, with Insights into Frailty: a Qualitative Study in Greek Primary Care
Polypharmacy is increasing among older individuals worldwide. Deprescribing has been suggested as a strategy to reduce pol...
Safety and Efficacy of Sodium-Glucose Cotransporter 2 Inhibitors in Older Adults with Variable Disease States: A Meta-analysis of Large Placebo-Controlled Trials
Safety and Efficacy of Sodium-Glucose Cotransporter 2 Inhibitors in Older Adults with Variable Disease States: A Meta-analysis of Large Placebo-Controlled Trials
Recent guidelines recommend the use of sodium-glucose cotransporter 2 (SGLT-2) inhibitors (SGLT2i) in patients suffering f...
Dementia Medications and Their Association with Pain Medication Use in Medicare Beneficiaries with Alzheimer’s Disease/Alzheimer’s Disease-Related Dementias and Chronic Pain
Dementia Medications and Their Association with Pain Medication Use in Medicare Beneficiaries with Alzheimer’s Disease/Alzheimer’s Disease-Related Dementias and Chronic Pain
Chronic pain is prevalent among older adults with Alzheimer’s disease (AD) and Alzheimer’s disease-related dem...
Trazodone and Risk of Orthostatic Hypotension, Syncope and Falls in Geriatric Outpatients with Hypertension
Trazodone and Risk of Orthostatic Hypotension, Syncope and Falls in Geriatric Outpatients with Hypertension
In older adults, trazodone is frequently prescribed for anxiety and insomnia owing to its perceived greater tolerability i...
Medicine Optimisation and Deprescribing Intervention Outcomes for Older People with Dementia or Mild Cognitive Impairment: A Systematic Review
Medicine Optimisation and Deprescribing Intervention Outcomes for Older People with Dementia or Mild Cognitive Impairment: A Systematic Review
Polypharmacy is common amongst older people with dementia or mild cognitive impairment (MCI), increasing the risk of medic...
Impact of Disease-Modifying Antirheumatic Drugs on Cognitive Function in Older Adults with Rheumatoid Arthritis
Impact of Disease-Modifying Antirheumatic Drugs on Cognitive Function in Older Adults with Rheumatoid Arthritis
Cognitive impairment poses significant challenges for aging populations. Systemic inflammation, a hallmark of rheumatoid a...
A Post Hoc Analysis of Older Patients with Metastatic Colorectal Cancer Receiving Oxaliplatin-Based Chemotherapy Plus Bevacizumab: The Randomized Obelics Study
A Post Hoc Analysis of Older Patients with Metastatic Colorectal Cancer Receiving Oxaliplatin-Based Chemotherapy Plus Bevacizumab: The Randomized Obelics Study
Phase II trials and subgroup analyses of clinical studies suggest that bevacizumab plus an oxaliplatin-based chemotherapy ...
Prescription and Non-prescription Medication Pill Burdens and Their Associations with Health-Related Quality of Life in Older Adults: A Cross-Sectional Study
Prescription and Non-prescription Medication Pill Burdens and Their Associations with Health-Related Quality of Life in Older Adults: A Cross-Sectional Study
Polypharmacy is associated with reduced health-related quality of life (HRQoL). This study explores the association betwee...
International Deprescribing Guidelines Did Not Impact Actual Practice in Deprescribing of Potentially Inappropriate Medications for Nursing Home Residents: An Interrupted Time Series Analysis
International Deprescribing Guidelines Did Not Impact Actual Practice in Deprescribing of Potentially Inappropriate Medications for Nursing Home Residents: An Interrupted Time Series Analysis
Deprescribing guidelines reduce the use of potentially inappropriate medications (PIMs) in trial settings; however, their ...
Potentially Inappropriate Psychotropic Drugs in Nursing Homes: An Italian Observational Study
Potentially Inappropriate Psychotropic Drugs in Nursing Homes: An Italian Observational Study
Physicians often face difficulties in selecting appropriate medications for older adults with multiple comorbidities. As p...
Cutaneous Lupus Erythematosus: Review and Considerations for Older Populations
Cutaneous Lupus Erythematosus: Review and Considerations for Older Populations
Though more common earlier in life, increasing attention is being focused on the development of cutaneous lupus erythemato...
A Trial-Based Cost-Utility Analysis of a Medication Optimization Intervention Versus Standard Care in Older Adults
A Trial-Based Cost-Utility Analysis of a Medication Optimization Intervention Versus Standard Care in Older Adults
Older adults are at greater risk of medication-related harm than younger adults. The Integrated Medication Management mode...
Evaluating the Safety of an Educational Deprescribing Intervention: Lessons from the Optimize Trial
Evaluating the Safety of an Educational Deprescribing Intervention: Lessons from the Optimize Trial
Patients, family members, and clinicians express concerns about potential adverse drug withdrawal events (ADWEs) following...
Potentially inappropriate prescribing in multimorbid and polymedicated older adults with AF: A Systematic Review and Meta-Analysis
Potentially inappropriate prescribing in multimorbid and polymedicated older adults with AF: A Systematic Review and Meta-Analysis
Polypharmacy in multimorbid older patients with atrial fibrillation (AF) is a risk factor for potentially inappropriate pr...
Current Pharmacological Therapies for the Management of Spondyloarthritis: Special Considerations in Older Patients
Current Pharmacological Therapies for the Management of Spondyloarthritis: Special Considerations in Older Patients
Spondylarthritis (SpA) is generally observed in young male patients but can be diagnosed in older patients. These cases co...
Polypharmacy and Antibody Response to SARS-CoV-2 Vaccination in Residents of Long-Term Care Facilities: The GeroCovid Vax Study
Polypharmacy and Antibody Response to SARS-CoV-2 Vaccination in Residents of Long-Term Care Facilities: The GeroCovid Vax Study
Polypharmacy is common in older adults, particularly among those living in long-term care facilities. This condition repre...
Prevalence and factors associated with inappropriate dosing of apixaban and rivaroxaban in hospitalized older adults with atrial fibrillation: a cross-sectional study
Prevalence and factors associated with inappropriate dosing of apixaban and rivaroxaban in hospitalized older adults with atrial fibrillation: a cross-sectional study
Atrial fibrillation (AF) is a common condition among older adults, requiring anticoagulation therapy to prevent thromboemb...
Factors Associated with Psychotropic Medication Use in People Living with Dementia in the Community: A Systematic Review and Meta-Analysis
Factors Associated with Psychotropic Medication Use in People Living with Dementia in the Community: A Systematic Review and Meta-Analysis
There has been considerable focus on the use of psychotropic agents in people living with dementia in long-term care. Howe...
NSAIDs for Pain Control During the Peri-Operative Period of Hip Fracture Surgery: A Systematic Review
NSAIDs for Pain Control During the Peri-Operative Period of Hip Fracture Surgery: A Systematic Review
Hip fracture (HF) mostly affects older adults and is responsible for increased morbidity and mortality. Non-steroidal anti...
Five-Year Follow-Up of Diabetic Complications and Geriatric Alterations in French Older Patients with Type 2 Diabetes According to Treatment Modalities: The Observational Prospective GERODIAB Cohort
Five-Year Follow-Up of Diabetic Complications and Geriatric Alterations in French Older Patients with Type 2 Diabetes According to Treatment Modalities: The Observational Prospective GERODIAB Cohort
Little is known about clinical events occurring in older patients with type 2 diabetes mellitus according to their therape...
Low-Income Older Adults’ Vulnerability to Anticholinergic Medication-Associated Frailty
Low-Income Older Adults’ Vulnerability to Anticholinergic Medication-Associated Frailty
A growing body of research supports the negative impact of anticholinergic drug burden on physical frailty. However, prior...
Load More
format_indent_increase