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Resetting the aging clock through epigenetic reprogramming: Insights from natural products
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The multifaceted role of agents counteracting metabolic syndrome: A new hope for gastrointestinal cancer therapy
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Effect of cannabinoids on the efficacy and side effects of anticancer therapeutic strategies – Current status of preclinical and clinical research
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GLP-1 receptor agonists, are we witnessing the emergence of a paradigm shift for neuro-cardio-metabolic disorders?
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The (neuro)inflammatory system in anxiety disorders and PTSD: Potential treatment targets
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The role of macrophages in asthma-related fibrosis and remodelling
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Recent advances in target identification technology of natural products
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Neuroimmune modulators derived from natural products: Mechanisms and potential therapies
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The anti-inflammatory effects of saponins from natural herbs
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Improvement of chronic metabolic inflammation and regulation of gut homeostasis: Tea as a potential therapy
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G protein-coupled estrogen receptor biased signaling in health and disease
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Biased agonism in peptide-GPCRs: A structural perspective
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Receptor dimers and biased ligands: Novel strategies for targeting G protein-coupled receptors
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Fibroblast growth factor receptor signaling in metabolic dysfunction-associated fatty liver disease: Pathogenesis and therapeutic targets
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Inflammatory bowel disease and neuropsychiatric disorders: Mechanisms and emerging therapeutics targeting the microbiota-gut-brain axis
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Understanding the regulatory landscape of protein phosphatase 2A (PP2A): Pharmacological modulators and potential therapeutics
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Plant-derived nanovesicles and therapeutic application
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Investigation into biased signaling, glycosylation, and drug vulnerability of acute myeloid leukemia
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G-protein coupled receptors in metabolic reprogramming and cancer
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Organic cation transporters in psychiatric and substance use disorders
Organic cation transporters in psychiatric and substance use disorders
Psychiatric and substance use disorders pose significant public health burdens across the globe. An estimated 970 million ...
Clinical advances in TNC delivery vectors and their conjugate agents
Clinical advances in TNC delivery vectors and their conjugate agents
Tenascin C (TNC), a glycoprotein that is abundant in the tumor extracellular matrix (ECM), is strongly overexpressed in tu...
Emerging roles of RNA ac4C modification and NAT10 in mammalian development and human diseases
Emerging roles of RNA ac4C modification and NAT10 in mammalian development and human diseases
Available online 7 December 2023, 108576Author links open overlay panel, , , , , , , , , , AbstractRNA ac4C modification i...
Hypertension & dementia: Pathophysiology & potential utility of antihypertensives in reducing disease burden
Hypertension & dementia: Pathophysiology & potential utility of antihypertensives in reducing disease burden
Dementia is a progressive neurodegenerative disease that develops most commonly in late adulthood and is predominantly cha...
Repurposing of pexidartinib for microglia depletion and renewal
Repurposing of pexidartinib for microglia depletion and renewal
Available online 3 December 2023, 108565Author links open overlay panel, , , AbstractPexidartinib (PLX3397) is a small mol...
Retracing our steps: A review on autism research in children, its limitation and impending pharmacological interventions
Retracing our steps: A review on autism research in children, its limitation and impending pharmacological interventions
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by three core impairments: impaired communic...
Therapeutic potential of stem cells in regeneration of liver in chronic liver diseases: Current perspectives and future challenges
Therapeutic potential of stem cells in regeneration of liver in chronic liver diseases: Current perspectives and future challenges
Chronic liver diseases (CLDs) are the leading cause of liver-related fatalities, accounting for 2 million deaths yearly (D...
Emerging role of immune cells as drivers of pulmonary fibrosis
Emerging role of immune cells as drivers of pulmonary fibrosis
Pulmonary fibrosis is an irreversible condition where the tissue (interstitium) surrounding the small air sacs (alveoli) i...
Retinoid X receptor agonists as selective modulators of the immune system for the treatment of cancer
Retinoid X receptor agonists as selective modulators of the immune system for the treatment of cancer
Retinoid X receptors (RXRs) are essential modulators of human physiology and attractive targets for treating cancer (Altuc...
What matters in aging is signaling for responsiveness
What matters in aging is signaling for responsiveness
Aging has traditionally been viewed as a multifaceted process influenced by various factors, including genetics, environme...
From exploring cancer and virus targets to discovering active peptides through mRNA display
From exploring cancer and virus targets to discovering active peptides through mRNA display
At first glance, cancer and viral infections have nothing in common – and, indeed, the differences run deep. However, from...
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