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Causality assessment of adverse drug reaction: A narrative review to find the most exhaustive and easy-to-use tool in post-authorization settings
Background: The core motive of pharmacovigilance is the detection and prevention of adverse drug reactions (ADRs), to impr...
Sequential hybrid ablation versus surgical CryoMaze alone for treatment of atrial fibrillation (SurHyb Trial): a protocol of the multicentre randomized controlled trial
Background: Atrial fibrillation is common in patients with structural heart disease who are undergoing cardiac surgery. Su...
In vitro study of Nigella sativa and thymoquinone activity on endothelial activation and monocyte adhesion
Introduction: Thymoquinone (TQ) is one of the bioactive compounds in Nigella sativa (NS). Also known as black seeds/cumin,...
Antioxidant action of xanthine oxidase inhibitor febuxostat protects the liver and blood vasculature in SHRSP5/Dmcr rats
Background: Xanthine oxidase (XO) generates reactive oxygen species during uric acid production. Therefore, XO inhibitors,...
The hepatoprotective effect of Sophora viciifolia fruit extract against acetaminophen-induced liver injury in mice
This research demonstrated the protective effect and possible mechanism of the Sophora viciifolia extract (SVE) against ac...
Experimental study on clinical and morphological determination of the optimal cannula diameter for lipoaspirate harvest from rabbit inguinal fat pad
Determining the most appropriate cannula diameter for lipoaspirate harvesting is important, both in terms of the quality a...
Closed reduction and minimally invasive screw osteosynthesis of Pipkin femoral head fractures
Background: Femoral posterior hip dislocation with associated femoral head fractures (Pipkin fractures) are rare high-ener...
hKLK alleviates myocardial fibrosis in mice with viral myocarditis
Myocardial fibrosis is the most serious complication of viral myocarditis (VMC). This study aimed to investigate the thera...
As a novel anticancer candidate, ether extract of Dendrobium nobile overstimulates cellular protein biosynthesis to induce cell stress and autophagy
Increasing data has confirmed the potential anticancer properties of Dendrobium, a traditional Chinese herb. However, most...
Amaryllidaceae alkaloids in skin cancer management: Photoprotective effect on human keratinocytes and anti-proliferative activity in melanoma cells
Skin cancer has high rates of mortality and therapeutic failure. In this study, to develop a multi-agent strategy for skin...
Effects of oleanolic acid on hair growth in mouse dorsal skin mediated via regulation of inflammatory cytokines
Oleanolic acid (OA) is a pentacyclic triterpenoid with favourable physiological activity. It is widely distributed in more...
Comparison of cardiocerebrovascular disease incidence between angiotensin converting enzyme inhibitor and angiotensin receptor blocker users in a real-world cohort
Background: Both angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) are known to...
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