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Selective imaging probes for differential detection of pathological tau polymorphs in tauopathies
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Advancing ocular gene therapy: a machine learning approach to enhance delivery, uptake and gene expression
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Artificial intelligence in preclinical research: enhancing digital twins and organ-on-chip to reduce animal testing
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Advances in artificial intelligence-envisioned technologies for protein and nucleic acid research
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Leveraging mHealth wearables for managing patients with Alzheimer’s disease: a scoping review
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An overview of progress in human metapneumovirus (hMPV) research: Structure, function, and therapeutic opportunities
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A cutting-edge solution to a Gordian knot? Aptamers targeting cancer stem cell markers for strategic cancer therapy
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DCTPP1: A promising target in cancer therapy and prognosis through nucleotide metabolism
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Computational modeling approaches and regulatory pathways for drug combinations
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The connection between Bayesian networks and adverse outcome pathway (AOP) networks and how to use it for predicting drug toxicity
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JAK inhibitors as a promising therapy for immune-mediated photodermatoses
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Are leukotrienes really the world’s best bronchoconstrictors and at least 100 to 1000 times more potent than histamine?
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Pathogenic TDP-43 in amyotrophic lateral sclerosis
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Evaluation of the implementation effectiveness of accelerated drug marketing registration procedures in China: lessons from the 2016–2024 regulatory review
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The spindle assembly checkpoint: Molecular mechanisms and kinase-targeted drug discovery
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Targeting FLT3 for treating diseases: FLT3 inhibitors
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Therapeutic potential of targeting ubiquitin-specific proteases in colorectal cancer
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Advancing atherosclerosis treatment: Drug encapsulation nanosystems and synthetic HDL nanoparticles
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Novel mechanisms underlying rapid-acting antidepressants: ketamine-like compounds, neurosteroid GABAkines, and psychedelics
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Genetic–epigenetic targets for PCOS-associated diabesity
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Fighting fire with fire: the immune system might be key in our fight against Alzheimer’s disease
Pieter Dujardin is a PhD student at Ghent University and the VIB-UGent Center for Inflammation Research in Ghent, Belgium....
Role of siRNA-based nanocarriers for the treatment of neurodegenerative diseases
Available online 10 January 2022Highlights•The clinical application of siRNA for brain disease therapy remains a significa...
The changing landscape of treatment options in childhood acute lymphoblastic leukaemia
Available online 7 January 2022Highlights•Paediatric acute lymphoblastic leukaemia remains an active research area.•First ...
Dendrimer nanoplatforms for veterinary medicine applications: a concise overview
Available online 6 January 2022Highlights•The sick animal is indeed a threat to man.•Dendrimer nanoplatforms can be used f...
Enhancing access to innovative cancer drugs: cross-sector consensus on a way forward to benefit patients
Available online 22 December 2021Highlights•New discoveries are driving advances in our understanding of cancer and its ev...
Applications of density functional theory in COVID-19 drug modeling
Available online 23 December 2021Highlights•Rapidly evolving COVID-19 pandemic demands the discovery of effective antivira...
Experimental murine models of brainstem gliomas
Available online 23 December 2021Highlights•Brainstem glioma (BG) is a highly aggressive malignancy with poor prognosis.•T...
Organoid and microfluidics-based platforms for drug screening in COVID-19
Catherine Verfaillie is professor in the Faculty of Medicine and head of Stem Cell and Developmental Biology at the Kathol...
Therapeutic potential of targeting regulatory mechanisms of hepatic stellate cell activation in liver fibrosis
Kaveh Baghaei is a principle investigator at the Shahid Beheshti Medical University-Research Institute of Gastroenterology...
Current clinical trials for epigenetic targets and therapeutic inhibitors for pancreatic cancer therapy
Available online 21 December 2021Highlights•Discusses the epigenetic mechanism in pancreatic cancer (PC).•Explores the met...
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