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Study protocol: HiSNAP trial - a multi-centre, randomised, open label, blinded end-point, safety and efficacy trial of conventional (300mg/kg) versus higher doses of acetylcysteine (450mg/kg and 600mg/kg) in patients with paracetamol overdose in the United Kingdom
Study protocol: HiSNAP trial - a multi-centre, randomised, open label, blinded end-point, safety and efficacy trial of conventional (300mg/kg) versus higher doses of acetylcysteine (450mg/kg and 600mg/kg) in patients with paracetamol overdose in the United Kingdom
medRxiv - The Preprint Server for Health Sciences
Global Lipidomic and Metabolomic Uncovers Blood Signatures of Left Ventricular Assist Devices for Heart Failure
Global Lipidomic and Metabolomic Uncovers Blood Signatures of Left Ventricular Assist Devices for Heart Failure
medRxiv - The Preprint Server for Health Sciences
FARFOOD: A database of potential interactions between food compounds and drugs.
FARFOOD: A database of potential interactions between food compounds and drugs.
medRxiv - The Preprint Server for Health Sciences
Trends and patterns of sedative prescribing in primary care in Ireland between 2014 and 2022 - a repeated cross-sectional study
Trends and patterns of sedative prescribing in primary care in Ireland between 2014 and 2022 - a repeated cross-sectional study
medRxiv - The Preprint Server for Health Sciences
Alternative dosing regimens of GLP-1 receptor agonists may reduce costs and maintain efficacy
Alternative dosing regimens of GLP-1 receptor agonists may reduce costs and maintain efficacy
medRxiv - The Preprint Server for Health Sciences
Effect of levodopa/carbidopa on the progression of Machado-Joseph disease /spinocerebellar ataxia type 3 (MJD/SCA3)
Effect of levodopa/carbidopa on the progression of Machado-Joseph disease /spinocerebellar ataxia type 3 (MJD/SCA3)
medRxiv - The Preprint Server for Health Sciences
Association between the use of levodopa/carbidopa and the disease outcomes included in the National Alzheimer Coordinating Center Uniform Data Set
Association between the use of levodopa/carbidopa and the disease outcomes included in the National Alzheimer Coordinating Center Uniform Data Set
medRxiv - The Preprint Server for Health Sciences
Low dose oral ketamine treatment on post-traumatic stress disorder (PTSD) (OKTOP): An open-label pilot study
Low dose oral ketamine treatment on post-traumatic stress disorder (PTSD) (OKTOP): An open-label pilot study
medRxiv - The Preprint Server for Health Sciences
Real-world safety of zonisamide: Mining and analysis of adverse events related to zonisamide based on FAERS database
Real-world safety of zonisamide: Mining and analysis of adverse events related to zonisamide based on FAERS database
medRxiv - The Preprint Server for Health Sciences
Simulate Scientific Reasoning with Multiple Large Language Models: An Application to Alzheimer's Disease Combinatorial Therapy
Simulate Scientific Reasoning with Multiple Large Language Models: An Application to Alzheimer's Disease Combinatorial Therapy
medRxiv - The Preprint Server for Health Sciences
CSF pharmacokinetics-pharmacodynamics of linezolid in critically brain injured patients, with or without central nervous system healthcare-associated infection. The PK-Pop-LCR Study: A Multicenter Pharmacokinetics and Pharmacodynamics Population Study.
CSF pharmacokinetics-pharmacodynamics of linezolid in critically brain injured patients, with or without central nervous system healthcare-associated infection. The PK-Pop-LCR Study: A Multicenter Pharmacokinetics and Pharmacodynamics Population Study.
medRxiv - The Preprint Server for Health Sciences
Pragmatic modeling supports current dosing guidelines for carbamazepine and valproic acid for the treatment of epilepsy in children
Pragmatic modeling supports current dosing guidelines for carbamazepine and valproic acid for the treatment of epilepsy in children
medRxiv - The Preprint Server for Health Sciences
Safety, tolerability and clinical effects of BC007 on fatigue and quality of life in patients with post-COVID syndrome (reCOVer): a prospective, exploratory, randomised , placebo-controlled, double-blind, crossover phase IIa clinical trial
Safety, tolerability and clinical effects of BC007 on fatigue and quality of life in patients with post-COVID syndrome (reCOVer): a prospective, exploratory, randomised , placebo-controlled, double-blind, crossover phase IIa clinical trial
medRxiv - The Preprint Server for Health Sciences
Eq-DIAGNOBATCH, a Shiny application for topical product equivalence with batch effect and multivariate outlier analysis
Eq-DIAGNOBATCH, a Shiny application for topical product equivalence with batch effect and multivariate outlier analysis
medRxiv - The Preprint Server for Health Sciences
Sotalol dose optimization for fetal tachycardia: a pregnancy physiologically based pharmacokinetic model study.
Sotalol dose optimization for fetal tachycardia: a pregnancy physiologically based pharmacokinetic model study.
medRxiv - The Preprint Server for Health Sciences
No one-size-fits-all approach: Retrospective analysis of efficacy and safety of serum concentrations of continuously administered vancomycin in critically ill adults reveals different target serum concentrations depending on disease severity
No one-size-fits-all approach: Retrospective analysis of efficacy and safety of serum concentrations of continuously administered vancomycin in critically ill adults reveals different target serum concentrations depending on disease severity
medRxiv - The Preprint Server for Health Sciences
A Non-Pharmacological, Nociceutical Formulation Lessens Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients
A Non-Pharmacological, Nociceutical Formulation Lessens Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients
medRxiv - The Preprint Server for Health Sciences
Exploring Drug Repurposing for Rare Diseases: Leveraging Biomedical Knowledge Graphs and Access to Scientific Literature
Exploring Drug Repurposing for Rare Diseases: Leveraging Biomedical Knowledge Graphs and Access to Scientific Literature
medRxiv - The Preprint Server for Health Sciences
Ivabradine and Atrial Fibrillation Incidence: A Nested Matching Study
Ivabradine and Atrial Fibrillation Incidence: A Nested Matching Study
medRxiv - The Preprint Server for Health Sciences
Integrative proteogenomics study identifies the indirect effect of circulating proteins on 8 diseases via telomere length
Integrative proteogenomics study identifies the indirect effect of circulating proteins on 8 diseases via telomere length
medRxiv - The Preprint Server for Health Sciences
Investigation of genomic and transcriptomic risk factors in clopidogrel response in African Americans.
Investigation of genomic and transcriptomic risk factors in clopidogrel response in African Americans.
medRxiv - The Preprint Server for Health Sciences
Effect of RAS Inhibitors in Acute Ischemic Stroke to Improve Outcomes: A Cross Sectional and Longitudinal Analysis.
Effect of RAS Inhibitors in Acute Ischemic Stroke to Improve Outcomes: A Cross Sectional and Longitudinal Analysis.
medRxiv - The Preprint Server for Health Sciences
Mendelian randomization analysis supports Factors II and XI as actionable anticoagulant targets
Mendelian randomization analysis supports Factors II and XI as actionable anticoagulant targets
medRxiv - The Preprint Server for Health Sciences
SLCO1B1 functional variants and statin-induced myopathy in people with recent genealogical ancestors from Africa: a population-based real-world study.
SLCO1B1 functional variants and statin-induced myopathy in people with recent genealogical ancestors from Africa: a population-based real-world study.
medRxiv - The Preprint Server for Health Sciences
Thyroid hyperplasia and neoplasm adverse events associated with GLP-1 receptor agonists in FDA Adverse Event Reporting System
Thyroid hyperplasia and neoplasm adverse events associated with GLP-1 receptor agonists in FDA Adverse Event Reporting System
medRxiv - The Preprint Server for Health Sciences
Availability, market share and price of quality assured artemisinin-based combination therapies in private drug outlets after over a decade of Copayment mechanism in Uganda.
Availability, market share and price of quality assured artemisinin-based combination therapies in private drug outlets after over a decade of Copayment mechanism in Uganda.
medRxiv - The Preprint Server for Health Sciences
Effects of testosterone and metformin on the GlycanAge index of biological age and the composition of the IgG glycome
Effects of testosterone and metformin on the GlycanAge index of biological age and the composition of the IgG glycome
medRxiv - The Preprint Server for Health Sciences
Oxytocin-augmented modular-based group intervention for loneliness: A proof-of-concept randomized-controlled trial
Oxytocin-augmented modular-based group intervention for loneliness: A proof-of-concept randomized-controlled trial
medRxiv - The Preprint Server for Health Sciences
Phenotypic models of drug-drug-gene interactions mediated by cytochrome drug-metabolizing enzymes
Phenotypic models of drug-drug-gene interactions mediated by cytochrome drug-metabolizing enzymes
medRxiv - The Preprint Server for Health Sciences
Effectiveness and safety of drugs in pregnancy: evidence from drug target Mendelian randomization
Effectiveness and safety of drugs in pregnancy: evidence from drug target Mendelian randomization
medRxiv - The Preprint Server for Health Sciences
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