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Tailoring the release of highly loaded amorphous solid dispersions via additive manufacturing
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Engineering IgG antibodies for intracellular targeting and drug delivery
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The therapeutic potential of mRNA-encoded SFTSV human monoclonal antibody encapsulated lipid nanoparticle in vivo
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Enhancing the bystander effect of antibody-drug conjugate by using a novel caspase-3 cleavable peptide linker to overcome tumor heterogeneity
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Oxidized fucoidan-based nanocomposite hydrogel for cryptotanshinone delivery and prevention of postoperative abdominal adhesions
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Synergistic chemo-photothermal treatment via MXene-encapsulated nanoparticles for targeted melanoma therapy
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Glycogen-inspired trimannosylated serum albumin nanocarriers for targeted delivery of toll-like receptor 7/8 agonists to immune cells and liver
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Sonopermeation combined with stroma normalization enables complete cure using nano-immunotherapy in murine breast tumors
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Tough and waterproof microneedles overcome mucosal immunotolerance by modulating antigen release patterns
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Corrigendum to “Overcoming P-glycoprotein-mediated multidrug resistance in cancer cells through micelle-forming PHPMA-b-PPO diblock copolymers for doxorubicin delivery” [Journal of Controlled Release 381 (2025) 113645]
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Corrigendum to “Dual-responsive nanoparticles for enhanced drug delivery in breast cancer chemotherapy” [Volume 377, 10 January 2025, Pages 146–161]
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Incorporation of cellular membrane protein extracts into lipid nanoparticles enhances their cellular uptake and mRNA delivery efficiency
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Visible-light-triggered recovery of biologically intact cells using smart fluoropolymer-nanocoated materials
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Potent therapeutic efficacy of intranasally deliverable paclitaxel modified with pH-sensitive and PEGylated polymeric micelle against glioblastoma
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It's not right, it's not even wrong
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Bone marrow vessels are hyperpermeable to macromolecules and nanoscale medicine in a size-dependent manner
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Design of lipid-based formulations for oral delivery of a BASP1 peptide targeting MYC-dependent gastrointestinal cancer cells
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Decellularized extracellular matrix as a drug delivery carrier
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PD-L1 targeted antibody-polymer-Epirubicin conjugate prolongs survival in a preclinical murine model of advanced ovarian cancer
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Gentle and efficient engineering of primary human NK cells by photoporation with polydopamine nanosensitizers
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pH-dependent pressure-sensitive colonic capsules for the delivery of aqueous bacterial suspensions
pH-dependent pressure-sensitive colonic capsules for the delivery of aqueous bacterial suspensions
Microbiome-based therapies hold great promise for treating various diseases, but the efficient delivery of live bacteria t...
A radioactive CRISPR interference system using 89Zr-labeled LbCas12a
A radioactive CRISPR interference system using 89Zr-labeled LbCas12a
Recently, CRISPR proteins have been recognized as promising candidates for drug development. However, there is still a lac...
Antigen-specific T cell activation through targeted delivery of in-situ generated antigen and calcium ionophore to enhance antitumor immunotherapy
Antigen-specific T cell activation through targeted delivery of in-situ generated antigen and calcium ionophore to enhance antitumor immunotherapy
Current cancer immunotherapy primarily focuses on the activation of T cells to initiate an immune response. The sustained ...
MicroRNA-195 liposomes for therapy of Alzheimer's disease
MicroRNA-195 liposomes for therapy of Alzheimer's disease
Alzheimer's disease (AD) is a progressive disorder that starts with mild memory impairment and eventually results in a sev...
Effective delivery of miR-511-3p with mannose-decorated exosomes with RNA nanoparticles confers protection against asthma
Effective delivery of miR-511-3p with mannose-decorated exosomes with RNA nanoparticles confers protection against asthma
Our previous studies have shown that miR-511-3p treatment has a beneficial effect in alleviating allergic airway inflammat...
Co-delivery of oxaliplatin prodrug liposomes with Bacillus Calmette-Guérin for chemo-immunotherapy of orthotopic bladder cancer
Co-delivery of oxaliplatin prodrug liposomes with Bacillus Calmette-Guérin for chemo-immunotherapy of orthotopic bladder cancer
Bladder cancer (BC) is a prevalent and costly malignancy among urinary carcinomas globally, primarily due to the need for ...
Fish oil-based microemulsion can efficiently deliver oral peptide blocking PD-1/PD-L1 and simultaneously induce ferroptosis for cancer immunotherapy
Fish oil-based microemulsion can efficiently deliver oral peptide blocking PD-1/PD-L1 and simultaneously induce ferroptosis for cancer immunotherapy
In the past decade, significant advances have been made in cancer immunotherapy, demonstrating that the immune system, and...
Micronanoparticled risedronate exhibits potent vaccine adjuvant effects
Micronanoparticled risedronate exhibits potent vaccine adjuvant effects
Bisphosphonates (BPs) are derivatives of inorganic pyrophosphate, characterized by a highly stable phosphorus‑carbon‑phosp...
Albumin hydrogels for repeated capture of drugs from the bloodstream and release into the tumor
Albumin hydrogels for repeated capture of drugs from the bloodstream and release into the tumor
Malignant tumors are one of the leading causes of death worldwide [1,2]. Surgery is often the primary treatment option, pa...
Harnessing astaxanthin-loaded diselenium cross-linked apotransferrin nanoparticles for the treatment of secretory otitis media
Harnessing astaxanthin-loaded diselenium cross-linked apotransferrin nanoparticles for the treatment of secretory otitis media
Secretory otitis media (SOM) is a type of non-suppurative inflammation of the middle ear characterized by tympanic effusio...
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