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Preparation and Physicochemical Characterizations of Niosomal Benzoyl Peroxide and Clindamycin Phosphate Formulation for Acne Vulgaris
Preparation and Physicochemical Characterizations of Niosomal Benzoyl Peroxide and Clindamycin Phosphate Formulation for Acne Vulgaris
This study aimed to prepare and characterize a topical niosomal formulation of benzoyl peroxide (BP) and clindamycin phosp...
Formulation and Characterization of Interpenetrating Polymer Network Hydrogel Bead as Drug Carrier System for Extended Release of Sulphonyl Urea Medication
Formulation and Characterization of Interpenetrating Polymer Network Hydrogel Bead as Drug Carrier System for Extended Release of Sulphonyl Urea Medication
The study aims to develop an interpenetrating polymer network (IPN) hydrogel bead. This drug carrier system with a hydroph...
Surface Engineering and Optimizing DepoFoam System: A Robust Quality by Design Approach for Optimal Drug Delivery, Stability, and Quality
Surface Engineering and Optimizing DepoFoam System: A Robust Quality by Design Approach for Optimal Drug Delivery, Stability, and Quality
The study utilized non-ionic polymer macrogol to transform the surface properties of the DepoFoam drug carrier system, dev...
Effect of Rosa damascena Essential Oil Loaded in Nanostructured Lipid Carriers on the Proliferation of Human Breast Cancer Cell Line MDA-MB-231 in Comparison with Cisplatin
Effect of Rosa damascena Essential Oil Loaded in Nanostructured Lipid Carriers on the Proliferation of Human Breast Cancer Cell Line MDA-MB-231 in Comparison with Cisplatin
As Rosa damascena essential oils (RDEOs) have antioxidant, antibacterial, antiviral, and insecticidal activity, they could...
Development and Characterization of Glimepiride-Loaded Polymeric Nanoparticles: Formulation Design and Evaluation
Development and Characterization of Glimepiride-Loaded Polymeric Nanoparticles: Formulation Design and Evaluation
This study was aimed to develop polymeric nanoparticles (PNPs) using chitosan (CTN), polyvinyl pyrrolidone (PVP), and Twee...
Development and Evaluation of Novel Amoxicillin and Phytic Acid-Loaded Gastro-Retentive Mucoadhesive Pectin Microparticles for the Management of Helicobacter pylori Infections
Development and Evaluation of Novel Amoxicillin and Phytic Acid-Loaded Gastro-Retentive Mucoadhesive Pectin Microparticles for the Management of Helicobacter pylori Infections
Amoxicillin, a treatment option widely employed against H. pylori infection, is becoming ineffective due to the rising ant...
Repurposing of IL 33/ST2 Modulating Drugs as a Cardioprotective Agent: A Promising Approach
Repurposing of IL 33/ST2 Modulating Drugs as a Cardioprotective Agent: A Promising Approach
Drug repurposing has emerged as an enigmatic clinical approach in disorders affecting the cardiovascular system. The conce...
Enhanced Oral Bioavailability of Isoformononetin Through Nanoemulsion: Development, Optimization, and Characterization
Enhanced Oral Bioavailability of Isoformononetin Through Nanoemulsion: Development, Optimization, and Characterization
Isoformononetin (IFN) is a methoxyl derivative of daidzein and has been stated as a potent osteogenic isoflavone. However,...
Assessment of Imaging Flow Cytometry for the Simultaneous Discrimination of Protein Particles and Silicone Oil Droplets in Biologicals
Assessment of Imaging Flow Cytometry for the Simultaneous Discrimination of Protein Particles and Silicone Oil Droplets in Biologicals
Silicone oil droplets in biopharmaceutical products can originate from sources such as siliconized surfaces of primary pac...
Integrated Continuous Process Design for Crystallisation, Spherical Agglomeration, and Filtration of Lovastatin
Integrated Continuous Process Design for Crystallisation, Spherical Agglomeration, and Filtration of Lovastatin
This work seeks to improve the particle processability of needle-like lovastatin crystals and develop a small-footprint co...
An Understanding of the Relationship Between Mixing Performance and Power Consumption in a High-Shear Wet Granulation Pre-mixing
An Understanding of the Relationship Between Mixing Performance and Power Consumption in a High-Shear Wet Granulation Pre-mixing
High-shear wet granulation (HSWG) is most commonly used in the pharmaceutical industry, with the advantages of being fully...
Fluconazole Microsponges Loaded Bioadhesive Vaginal Film to Treat Vulvovaginal Candidiasiss
Fluconazole Microsponges Loaded Bioadhesive Vaginal Film to Treat Vulvovaginal Candidiasiss
The purpose of this study was to develop fluconazole microsponges loaded bioadhesive film, rolled into a torpedo-shaped ca...
Design and Development of Immediate Release Pellets Formulation Containing Co Amorphous Mixture of Aceclofenac: In-Vitro and In-Vivo Study
Design and Development of Immediate Release Pellets Formulation Containing Co Amorphous Mixture of Aceclofenac: In-Vitro and In-Vivo Study
Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) belonging to BCS Class II, has a constraint over its therapeu...
Loss-on-Drying Prediction for a Vibrated Fluidised Bed Dryer by Means of Mass and Energy Balances
Loss-on-Drying Prediction for a Vibrated Fluidised Bed Dryer by Means of Mass and Energy Balances
Continuous wet granulation and drying require an adequate process control strategy to ensure the product quality. The most...
Exploring Liposomal Systems for Gallic Acid and Tannic Acid Delivery: Potential Strategies to Address Inflammation and Infections in Pediatric Ventricular Assist Device Recipients
Exploring Liposomal Systems for Gallic Acid and Tannic Acid Delivery: Potential Strategies to Address Inflammation and Infections in Pediatric Ventricular Assist Device Recipients
Pediatric heart failure imposes a significant health burden, necessitating effective interventions. Left ventricular assis...
Optimization, Formulation, and Stability of Topical Rapamycin Used for Rare Tuberous Sclerosis Disease: from Ointment to Liposomes
Optimization, Formulation, and Stability of Topical Rapamycin Used for Rare Tuberous Sclerosis Disease: from Ointment to Liposomes
Topical rapamycin has been established as an effective and safe therapy for facial angiofibromas in tuberous sclerosis. Di...
Topical Delivery of Methoxsalen Co-loaded Curcumin Using Hybrid Nanocarrier-Based Polymeric Hydrogel for Synergistic Therapy in the Treatment of Psoriasis
Topical Delivery of Methoxsalen Co-loaded Curcumin Using Hybrid Nanocarrier-Based Polymeric Hydrogel for Synergistic Therapy in the Treatment of Psoriasis
Psoriasis is a chronic autoimmune inflammatory cutaneous disorder, and single-drug therapy is inadequate for curing this d...
Exploiting response surface D-optimal design study for preparation and optimization of spanlastics loaded with miconazole nitrate as a model antifungal drug for topical application
Exploiting response surface D-optimal design study for preparation and optimization of spanlastics loaded with miconazole nitrate as a model antifungal drug for topical application
Skin fungal infections are widely spreading worldwide and are considered a main cause of skin, mucous membranes, and syste...
pH-Triggered Dynamic Carrier-Free Nanodrugs Self-Assembled from Dasatinib and Chlorambucil with a Potential for Precise Tumoral Targeting Theranostic
pH-Triggered Dynamic Carrier-Free Nanodrugs Self-Assembled from Dasatinib and Chlorambucil with a Potential for Precise Tumoral Targeting Theranostic
Dynamic carrier-free theranostic nanodrugs are in great demand, owing to their extraordinary high drug loading, enhanced t...
Formulation and Characterization of Luliconazole Microsponge Gel for Diaper Dermatitis
Formulation and Characterization of Luliconazole Microsponge Gel for Diaper Dermatitis
Many current drug delivery technologies are ineffective and require high concentrations of active drugs for effective ther...
Mechanism Changes with High Temperature: Significance for Use of Accelerated Aging Modeling of Pharmaceuticals
Mechanism Changes with High Temperature: Significance for Use of Accelerated Aging Modeling of Pharmaceuticals
This work evaluates the probability and impact of using high-temperature accelerated aging for determining shelf life base...
QBD Approach for Design and Characterization of Pramlintide Microspheres for Controlled Drug Release
QBD Approach for Design and Characterization of Pramlintide Microspheres for Controlled Drug Release
The research was centered on the optimization of the microsphere formulation through a systematic quality-by-design (QBD) ...
Study on the Correlation Between Nimodipine (BCS Class II) Solubility, Dissolution Improvement, and Brain Tissue Concentration Through Cocrystallization
Study on the Correlation Between Nimodipine (BCS Class II) Solubility, Dissolution Improvement, and Brain Tissue Concentration Through Cocrystallization
Cocrystallization by solvent evaporation was used to enhance the dissolution, physicochemical properties, and bioavailabil...
QbD-Driven Development and Characterization of Solid Lipid Nanoparticles (SLNs)–Based Nanogel of Luliconazole for the Effective Management of Dermal Fungal Infection
QbD-Driven Development and Characterization of Solid Lipid Nanoparticles (SLNs)–Based Nanogel of Luliconazole for the Effective Management of Dermal Fungal Infection
Solid lipid nanoparticles (SLNs) have shown tremendous utility in the topical delivery of such anti-fungal moieties. Hence...
Development, Characterization, and Ex Vivo Permeation Assessment of Diclofenac Diethylamine Deep Eutectic Systems Across Human Skin
Development, Characterization, and Ex Vivo Permeation Assessment of Diclofenac Diethylamine Deep Eutectic Systems Across Human Skin
The primary aim of this study is to introduce Therapeutic Deep Eutectic Systems (THEDES) as a novel, green, and biocompati...
Development, Optimization, and Evaluation of Nano-platforms for Delivery of siRNA and BPTES in c-Myc Induced Breast Cancer
Development, Optimization, and Evaluation of Nano-platforms for Delivery of siRNA and BPTES in c-Myc Induced Breast Cancer
siRNA therapeutics has emerged as a promising strategy for treating several “undruggable” genetically impaired...
SGLT-2i: Nanoparticular-Based Strategies, Solutions, and Clinical Applications in Opposition to Low Bioavailability
SGLT-2i: Nanoparticular-Based Strategies, Solutions, and Clinical Applications in Opposition to Low Bioavailability
Although SGLT-2i initially acquired prominence for usage in diabetes, they later emerged as the top medication class in bo...
Synthesis and Characterization of Cosmetic Grade Ionic Liquids and Their Application as Skin Whitening Agents
Synthesis and Characterization of Cosmetic Grade Ionic Liquids and Their Application as Skin Whitening Agents
Recent developments emphasize the ready conversion of known active pharmaceutical ingredients (APIs) into novel phases lik...
Effect of Manufacturing Conditions on Particle Characteristics in the Drug-Layering Process of a Novel Melt Granulation Technology, MALCORE®, Using a Design of Experiments
Effect of Manufacturing Conditions on Particle Characteristics in the Drug-Layering Process of a Novel Melt Granulation Technology, MALCORE®, Using a Design of Experiments
MALCORE®, a manufacturing technology of drug-containing particles (DCPs) for coating, consists of a 2-step melt granu...
Bioavailability Enhancement of Poorly Aqueous Soluble Atorvastatin Calcium by Solid Dispersion Technique Using a Modified Natural Polymer as a Hydrophilic Carrier
Bioavailability Enhancement of Poorly Aqueous Soluble Atorvastatin Calcium by Solid Dispersion Technique Using a Modified Natural Polymer as a Hydrophilic Carrier
The goal of this study was to improve the solubility and bioavailability of poorly water-soluble atorvastatin calcium (ATC...
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