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Curcumin-loaded Niosomes Prepared by Microfluidic Mixing; Characterization and Cytotoxicity Evaluation
Curcumin-loaded Niosomes Prepared by Microfluidic Mixing; Characterization and Cytotoxicity Evaluation
Curcumin is a commonly used natural chemical compound that has several reported therapeutic applications. Derived from Cur...
A Novel Prednisolone-Loaded Layer-by-Layer Nanoparticles (LBL-NPs) for Rheumatoid Arthritis: Optimization and Therapeutic Evaluation
A Novel Prednisolone-Loaded Layer-by-Layer Nanoparticles (LBL-NPs) for Rheumatoid Arthritis: Optimization and Therapeutic Evaluation
Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with bone erosion, inflammatory joint disease, and lo...
Formulation, In Vitro Characterization and Anti-Tuberculosis Investigation of Isoniazid NANOCAPSULES.
Formulation, In Vitro Characterization and Anti-Tuberculosis Investigation of Isoniazid NANOCAPSULES.
Tuberculosis (TB) is a major cause of mortality worldwide. The most commonly used first-line anti-TB drugs in the treatmen...
Development and Pharmacokinetic Evaluation of Binary Carrier-Based Solid Dispersion of Desidustat, a New Drug for Chronic Kidney Disease-Associated Anemia
Development and Pharmacokinetic Evaluation of Binary Carrier-Based Solid Dispersion of Desidustat, a New Drug for Chronic Kidney Disease-Associated Anemia
Desidustat is a new oral hypoxia-inducible factor prolyl hydroxylase inhibitor indicated for the management of chronic kid...
Phytochemical Composition and Bioactivities of (Briq.) Leaf Extracts: Antimicrobial and Antibiofilm Properties
Phytochemical Composition and Bioactivities of (Briq.) Leaf Extracts: Antimicrobial and Antibiofilm Properties
Many plants have been reported to exhibit both antimicrobial and anti-biofilm activities potentially serving as natural al...
Development of Bimatoprost-Loaded Nano Spanlastic In-Situ Gel for Ophthalmic Drug Delivery: A Box-Behnken Optimization Approach with In Vitro and Ex Vivo Characterization
Development of Bimatoprost-Loaded Nano Spanlastic In-Situ Gel for Ophthalmic Drug Delivery: A Box-Behnken Optimization Approach with In Vitro and Ex Vivo Characterization
The present study aimed to develop and optimize a Bimatoprost-loaded spanlastic in-situ gel to enhance precorneal retentio...
Protection of Mucous Membranes Against the Use of Biocides
Protection of Mucous Membranes Against the Use of Biocides
Biocides, in touch with the mucosa or skin, are capable of penetrating the mucosa or skin and causing possible local lesio...
Development and Evaluation of Benzydamine Hydrochloride-Loaded Pastilles for Local Delivery in the Oral Cavity
Development and Evaluation of Benzydamine Hydrochloride-Loaded Pastilles for Local Delivery in the Oral Cavity
Benzydamine hydrochloride (BZD) is a nonsteroidal anti-inflammatory drug commonly used for the relief of acute sore throat...
Formulation of Mixed Micelles of Various Model Drug Ionic Complexes in an Optimized Micellar Base Composed of Surfactants and Cosolvent Mixture: In Vitro Analysis of Drug Delivery Efficiency
Formulation of Mixed Micelles of Various Model Drug Ionic Complexes in an Optimized Micellar Base Composed of Surfactants and Cosolvent Mixture: In Vitro Analysis of Drug Delivery Efficiency
In this study, micellar complexes of various model drugs were developed and investigated for drug delivery efficiency. Pon...
An Integrated Computational and Experimental Framework for Investigating Flavonoid-driven Bioenhancement of Curcumin
An Integrated Computational and Experimental Framework for Investigating Flavonoid-driven Bioenhancement of Curcumin
Enhancing oral bioavailability remains a key focus in modern medicine. Among various bioenhancers, flavonoid polyphenols s...
Promising Alginate-Gelatin Scaffolds Containing 5-Fluorouracil and Reinforced with Zinc-Modified Hydroxyapatite: Cell Attachment and One-Year Stability Study
Promising Alginate-Gelatin Scaffolds Containing 5-Fluorouracil and Reinforced with Zinc-Modified Hydroxyapatite: Cell Attachment and One-Year Stability Study
The current study evaluated the cell attachment capability and long-term stability of 5-fluorouracil (5-FU) loaded alginat...
Exploring the Anti-Inflammatory Effects of Grape Seed Extract on Depressive Disorder: A Preclinical and Network Pharmacology Approach
Exploring the Anti-Inflammatory Effects of Grape Seed Extract on Depressive Disorder: A Preclinical and Network Pharmacology Approach
Grape seed extract (GSE) is a biotechnological input known for its anti-inflammatory and neuroprotective properties. This ...
Famotidine—A BCS Class III Drug: Design, Development, and Evaluation of a Stable Solid SDEDDS Formulation to Improve Permeation and Oral Bioavailability
Famotidine—A BCS Class III Drug: Design, Development, and Evaluation of a Stable Solid SDEDDS Formulation to Improve Permeation and Oral Bioavailability
This study aims to develop a stable solid self-double emulsifying drug delivery system (S-SDEDDS) for famotidine to improv...
Formulation, Optimization, and In Vitro Studies of Roasted Agung Banana var. Semeru Peel Effervescent Antidepressant Tablet
Formulation, Optimization, and In Vitro Studies of Roasted Agung Banana var. Semeru Peel Effervescent Antidepressant Tablet
To make effervescent tablet which being able to used for large doses of active ingredient, improve palatability, and simpl...
QbD-Based Development of Translabial Bupropion-Loaded Nanoemulstick for Brain-Targeted Dopamine Modulation in Smoking Cessation using PC12 Cell Lines
QbD-Based Development of Translabial Bupropion-Loaded Nanoemulstick for Brain-Targeted Dopamine Modulation in Smoking Cessation using PC12 Cell Lines
Bupropion (marketed as Wellbutrin), a potent antidepressant, eludes the typical side effects of somnolence, weight gain, a...
Thiocolchicoside Niosomal Gel: Design-Driven Optimization for Superior Skin Permeation
Thiocolchicoside Niosomal Gel: Design-Driven Optimization for Superior Skin Permeation
Rheumatoid Arthritis (RA) affects approximately 1.5 million people worldwide. Thiocolchicoside (THC) is commonly ...
Carrageenan Matrix for Sustained Levofloxacin Delivery: Formulation Strategies and Dual Evaluation Approaches
Carrageenan Matrix for Sustained Levofloxacin Delivery: Formulation Strategies and Dual Evaluation Approaches
This study presents the formulation and evaluation of a sustained-release matrix tablet for levofloxacin (LFX) using carra...
Development and Optimization of Setraconazole Invasomes, Gels, and Films for Enhanced Transdermal Delivery and Topical Fungal Treatment
Development and Optimization of Setraconazole Invasomes, Gels, and Films for Enhanced Transdermal Delivery and Topical Fungal Treatment
This study was undertaken to improve the treatment of deep seated fungal skin infection by formulation of setraconazole lo...
Development of Novel CS/PV/Ni/SCE Combination Hydrogel and Evaluation of their Potential in Drug Delivery and Tissue Regeneration Application
Development of Novel CS/PV/Ni/SCE Combination Hydrogel and Evaluation of their Potential in Drug Delivery and Tissue Regeneration Application
Toxicity of the biomaterials is one of the most important parameters that is considered while choosing a biopolymer for dr...
Preparation and Physicochemical Characterizations of Niosomal Benzoyl Peroxide and Clindamycin Phosphate Formulation for Acne Vulgaris
Preparation and Physicochemical Characterizations of Niosomal Benzoyl Peroxide and Clindamycin Phosphate Formulation for Acne Vulgaris
This study aimed to prepare and characterize a topical niosomal formulation of benzoyl peroxide (BP) and clindamycin phosp...
Formulation and Characterization of Interpenetrating Polymer Network Hydrogel Bead as Drug Carrier System for Extended Release of Sulphonyl Urea Medication
Formulation and Characterization of Interpenetrating Polymer Network Hydrogel Bead as Drug Carrier System for Extended Release of Sulphonyl Urea Medication
The study aims to develop an interpenetrating polymer network (IPN) hydrogel bead. This drug carrier system with a hydroph...
Surface Engineering and Optimizing DepoFoam System: A Robust Quality by Design Approach for Optimal Drug Delivery, Stability, and Quality
Surface Engineering and Optimizing DepoFoam System: A Robust Quality by Design Approach for Optimal Drug Delivery, Stability, and Quality
The study utilized non-ionic polymer macrogol to transform the surface properties of the DepoFoam drug carrier system, dev...
Effect of Rosa damascena Essential Oil Loaded in Nanostructured Lipid Carriers on the Proliferation of Human Breast Cancer Cell Line MDA-MB-231 in Comparison with Cisplatin
Effect of Rosa damascena Essential Oil Loaded in Nanostructured Lipid Carriers on the Proliferation of Human Breast Cancer Cell Line MDA-MB-231 in Comparison with Cisplatin
As Rosa damascena essential oils (RDEOs) have antioxidant, antibacterial, antiviral, and insecticidal activity, they could...
Development and Characterization of Glimepiride-Loaded Polymeric Nanoparticles: Formulation Design and Evaluation
Development and Characterization of Glimepiride-Loaded Polymeric Nanoparticles: Formulation Design and Evaluation
This study was aimed to develop polymeric nanoparticles (PNPs) using chitosan (CTN), polyvinyl pyrrolidone (PVP), and Twee...
Development and Evaluation of Novel Amoxicillin and Phytic Acid-Loaded Gastro-Retentive Mucoadhesive Pectin Microparticles for the Management of Helicobacter pylori Infections
Development and Evaluation of Novel Amoxicillin and Phytic Acid-Loaded Gastro-Retentive Mucoadhesive Pectin Microparticles for the Management of Helicobacter pylori Infections
Amoxicillin, a treatment option widely employed against H. pylori infection, is becoming ineffective due to the rising ant...
Repurposing of IL 33/ST2 Modulating Drugs as a Cardioprotective Agent: A Promising Approach
Repurposing of IL 33/ST2 Modulating Drugs as a Cardioprotective Agent: A Promising Approach
Drug repurposing has emerged as an enigmatic clinical approach in disorders affecting the cardiovascular system. The conce...
Enhanced Oral Bioavailability of Isoformononetin Through Nanoemulsion: Development, Optimization, and Characterization
Enhanced Oral Bioavailability of Isoformononetin Through Nanoemulsion: Development, Optimization, and Characterization
Isoformononetin (IFN) is a methoxyl derivative of daidzein and has been stated as a potent osteogenic isoflavone. However,...
Assessment of Imaging Flow Cytometry for the Simultaneous Discrimination of Protein Particles and Silicone Oil Droplets in Biologicals
Assessment of Imaging Flow Cytometry for the Simultaneous Discrimination of Protein Particles and Silicone Oil Droplets in Biologicals
Silicone oil droplets in biopharmaceutical products can originate from sources such as siliconized surfaces of primary pac...
Integrated Continuous Process Design for Crystallisation, Spherical Agglomeration, and Filtration of Lovastatin
Integrated Continuous Process Design for Crystallisation, Spherical Agglomeration, and Filtration of Lovastatin
This work seeks to improve the particle processability of needle-like lovastatin crystals and develop a small-footprint co...
An Understanding of the Relationship Between Mixing Performance and Power Consumption in a High-Shear Wet Granulation Pre-mixing
An Understanding of the Relationship Between Mixing Performance and Power Consumption in a High-Shear Wet Granulation Pre-mixing
High-shear wet granulation (HSWG) is most commonly used in the pharmaceutical industry, with the advantages of being fully...
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