Exploring Hybrid Nanoparticles for Crizotinib Delivery in Lung Cancer Treatment; Design, Optimization, In-vitro and Cell Line Evaluation

Shavi GV, et al. PEGylated liposomes of anastrozole for long-term treatment of breast cancer: in vitro and in vivo evaluation. J Liposome Res. 2016;26(1):28–46. https://doi.org/10.3109/08982104.2015.1029493.

Article  CAS  PubMed  Google Scholar 

Mukherjee AG, et al. Evolving strategies and application of proteins and peptide therapeutics in cancer treatment. Biomed Pharmacother. 2023;163:114832. https://doi.org/10.1016/j.biopha.2023.114832.

Article  CAS  PubMed  Google Scholar 

Niloufar R, et al. Nanoparticles in cancer diagnosis and treatment: Progress, challenges, and opportunities. J Drug Deliv Sci Technol. 2024;95:105599. https://doi.org/10.1016/j.jddst.2024.105599.

Article  CAS  Google Scholar 

Gavas S, Quazi S, Karpiński TM. Nanoparticles for cancer therapy: current progress and challenges. Nanoscale Res Lett. 2021;16(1):173. https://doi.org/10.1186/s11671-021-03628-6.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rani R, Agarwal V. Liposome and their applications in cancer therapy. Braz Arch Biol Technol. 2016;59. https://doi.org/10.1590/1678-4324-2016150477.

Yousefi Rizi HA, Shin DH, Yousefi Rizi S. Polymeric nanoparticles in cancer chemotherapy: A narrative review. Iran J Public Health. 2022;51(2):226–39. https://doi.org/10.18502/ijph.v51i2.8677.

Article  PubMed  PubMed Central  Google Scholar 

He C, Lu J, Lin W. Hybrid nanoparticles for combination therapy of cancer. J Control Release. 2015;219:224–36. https://doi.org/10.1016/j.jconrel.2015.09.029.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tariq H, Bokhari SAI. Surface-functionalised hybrid nanoparticles for targeted treatment of cancer. IET Nanobiotechnol. 2020;14(7):537–47. https://doi.org/10.1049/iet-nbt.2020.0073.

Article  PubMed  PubMed Central  Google Scholar 

Sahu A, et al. Crizotinib: A comprehensive review. South Asian J Cancer. 2013;2(2):91–7. https://doi.org/10.4103/2278-330X.110506.

Article  PubMed  PubMed Central  Google Scholar 

Xu H, et al. Evaluation of Crizotinib absolute bioavailability, the bioequivalence of three oral formulations, and the effect of food on Crizotinib pharmacokinetics in healthy subjects. J Clin Pharmacol. 2015;55(1):104–13. https://doi.org/10.1002/jcph.356.

Article  CAS  PubMed  Google Scholar 

Rahat I, et al. Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects. Beilstein J Nanotechnol. 2024;15:1473–97. https://doi.org/10.3762/bjnano.15.118.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gajbhiye KR, et al. Lipid polymer hybrid nanoparticles: a custom-tailored next-generation approach for cancer therapeutics. Mol Cancer. 2023;22(1):160. https://doi.org/10.1186/s12943-023-01849-0.

Article  PubMed  PubMed Central  Google Scholar 

Garg NK, et al. Development and characterization of single step self-assembled lipid polymer hybrid nanoparticles for effective delivery of methotrexate. RSC Adv. 2015;5(77):62989–99. https://doi.org/10.1039/C5RA12459J.

Article  CAS  Google Scholar 

Gajra B, Dalwadi C, R.J.D.J.o.P S, Patel. Formulation and optimization of itraconazole polymeric lipid hybrid nanoparticles (Lipomer) using box behnken design.Daru. J Pharm Sci. 2015;23(1):3. https://doi.org/10.1186/s40199-014-0087-0.

Article  CAS  Google Scholar 

Awadeen RH, et al. Formulation of lipid polymer hybrid nanoparticles of the phytochemical Fisetin and its in vivo assessment against severe acute pancreatitis. Sci Rep. 2023;13(1):19110. https://doi.org/10.1038/s41598-023-46215-8.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aman RM, Hashim IIA, M.J.E.J.o.P M. Novel chitosan-based solid-lipid nanoparticles to enhance the bio-residence of the miraculous phytochemical Apocynin. Eur J Pharm Sci. 2018;124:304–18. https://doi.org/10.1016/j.ejps.2018.09.001.

Article  CAS  PubMed  Google Scholar 

Gerweck LE, Seetharaman KJCr. Cellular pH gradient in tumor versus normal tissue: potential exploitation for the treatment of cancer. Cancer Res. 1996;56(6):1194–8. PMID: 8640796.

CAS  PubMed  Google Scholar 

Abdou EM, et al. Assessment of the hepatoprotective effect of developed lipid-polymer hybrid nanoparticles (LPHNPs) encapsulating naturally extracted β-Sitosterol against CCl4 induced hepatotoxicity in rats. Sci Rep. 2019;9(1):19779. https://doi.org/10.1038/s41598-019-56320-2.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shafique M, et al. Formulation development of lipid polymer hybrid nanoparticles of doxorubicin and its in-vitro, in-vivo and computational evaluation. Front Pharmacol. 2023;14:1025013. https://doi.org/10.3389/fphar.2023.1025013.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kumar R, et al. Drug encapsulated lipid-polymeric nanohybrid as a chemo-therapeutic platform of cancer. Nanothernostics. 2023;7(2):167. https://doi.org/10.7150/ntno.81173.

Article  Google Scholar 

Mohanty A, Uthaman S, Park I-KJM. Utilization of polymer-lipid hybrid nanoparticles for targeted anti-cancer therapy. Molecules. 2020;25(19):4377. https://doi.org/10.3390/molecules25194377.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kassaee SN, et al. Lipid polymer hybrid nanoparticles against lung cancer and their application as inhalable formulation. Nanomedicine. 2024;19(25):2113–33. https://doi.org/10.1080/17435889.2024.2387530.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nag S, et al. Hybrid lipid/polymer nanoparticles for pulmonary delivery of sirna: development and fate upon in vitro deposition on the human epithelial airway barrier. Handbook of lung targeted drug delivery systems. CRC; 2021. pp. 287–302. https://doi.org/10.1089/jamp.2017.1364.

Budhian A, Siegel SJ. I.J.I.j.o.p. Winey, Haloperidol-loaded PLGA nanoparticles: systematic study of particle size and drug content. Int J Pharm. 2007;336(2):367–75. https://doi.org/10.1016/j.ijpharm.2006.11.061.

Article  CAS  PubMed  Google Scholar 

Mainardes RM. And R.C.J.I.j.o.p. Evangelista, PLGA nanoparticles containing praziquantel: effect of formulation variables on size distribution. Int J Pharm. 2005;290(1–2):137–44. https://doi.org/10.1016/j.ijpharm.2004.11.027.

Article  CAS  PubMed  Google Scholar 

Sengel-Turk CT. C.J.J.o.d.d.s. Hascicek, and technology, Design of lipid-polymer hybrid nanoparticles for therapy of BPH: part I. Formulation optimization using a design of experiment approach. J Drug Deliv Sci Technol. 2017;39:16–27. https://doi.org/10.1016/j.jddst.2017.02.012.

Article  CAS  Google Scholar 

He C, et al. Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials. 2010;31(13):3657–66. https://doi.org/10.1016/j.biomaterials.2010.01.065.

Article  CAS  PubMed  Google Scholar 

Salel S, Iyisan BJDN. Polymer–lipid hybrid nanoparticles as potential lipophilic anticancer drug carriers. Discover Nano. 2023;18(1):114. https://doi.org/10.1186/s11671-023-03897-3.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Li Y, et al. Molecular interactions, internal structure and drug release kinetics of rationally developed polymer–lipid hybrid nanoparticles. J Control Release. 2008;128(1):60–70. https://doi.org/10.1016/j.jconrel.2008.02.014.

Article  CAS  PubMed  Google Scholar 

Jadon RS, J.o.D MJ, Technology. Docetaxel-loaded lipid-polymer hybrid nanoparticles for breast cancer therapeutics. J Drug Deliv Sci Technol. 2019;51:475–84. https://doi.org/10.1016/j.jddst.2019.03.039.

Comments (0)

No login
gif