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An isocratic HPLC-UV method for simultaneous quantification of tizanidine and lidocaine: Application to in vitro release studies of subcutaneous implant
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A review on surface modification of materials for 3D printed diagnostic devices
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Precise evaluation of batch adsorption kinetics of plant total polyphenols based on a flow-injection online spectrophotometric method
Efficient evaluation of adsorption kinetics of plant total polyphenols is essential for the design of adsorption separatio...
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Real-Time Kinetic Analysis and Detection of Glycated Hemoglobin A1c using Quartz Crystal Microbalance-Based Aptasensor
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Compressive Raman imaging by combining scattering-projection interleaving with context-aware excitation
Exciting an object with a laser-focus array and randomly interleaving its scattering projection has been proved to be an e...
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2-Aminopurine-based quencher-free DNA tweezer with well-tunable fluorescence property by surrounding bases
Reversible structural changes in DNA nanomachines have great potential in the field of bioanalysis. Here, we demonstrate a...
Analytical Methods
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Viscosity sensitive and AIE active bimodal fluorescent probe for selective detection of OCl¯ and Cu2+: dual sensing approach with DFT and biological study with green gram seeds
A novel dual mode viscosity sensitive and AIE active fluorescent chemosensor based on naphthalene coupled pyrene (NCP) moi...
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Scanning ion conductance microscopy revealed cisplatin-induced morphological changes related to apoptosis in single adenocarcinoma cells
The studies of drug induced apoptosis play a vital role in the identification of potential drugs that could treat diseases...
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A rhodamine coumarin-derived fluorescence probe that selectively detects Fe3+ and measures radiation doses
We synthesized a fluorescence ratiometric probe by combining coumarin and rhodamine B with ethylenediamine to sense Fe3+ a...
Analytical Methods
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A highly sensitive fluorescence probe for on-site detection of nerve agent mimic diethylchlorophosphonate DCP
Nerve agents are the most toxic chemical warfare agents that pose severe threat to human health and public security. In th...
Analytical Methods
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Enhanced portable detection for SARS-CoV-2 utilizing DNA tetrahedron-tethered aptamers and a pressure meter
Tethering oligonucleotide aptamers to a DNA tetrahedron structure can enhance the recognition of SARS-CoV-2 spike protein ...
Analytical Methods
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A facile fluorescence Eu MOF sensor for ascorbic acid and ascorbate oxidase detection
In this work, a facile fluorescence Eu3+-based metal organic frameworks (Eu MOF) sensor for ascorbic acid (AA) and ascorba...
Analytical Methods
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Metabolomic approaches to explore chemodiversity in seeds of guaraná (Paullinia cupana) using UPLC-QTOF-MSE and NMR analysis
The growing interest in health and well-being has spurred the evolution of functional foods, which provide enhanced health...
Analytical Methods
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In Situ Growth of Self-Supported CuO Nanorods from Cu-MOFs for Glucose Sensing and Elucidation its Sensing Mechanism
Herein, we present a simple and mild method to in situ prepare CuO nanostructures for non-enzymatic glucose sensing. Cu-me...
Analytical Methods
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A Lysosome-Targeted Fluorescent Probe Based on BODIPY Structure for Cys/Hcy Detection
Cysteine (Cys) and Homocysteine (Hcy) are important biothiols in living organisms. They play important roles in a variety ...
Analytical Methods
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An impedimetric sensor based on molecularly imprinted nanoparticles for the determination of trypsin in artificial matrixes - towards point-of-care diagnostics
A high-performance impedimetric sensing platform was designed to detect protein by employing molecularly imprinted polymer...
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Cu2+-doped zeolitic imidazolate frameworks and gold nanoparticles (AuNPs@ZIF-8/Cu) nanocomposites enable label-free and highly sensitive electrochemical detection of oral cancer-related biomarkers
It is of great significance to accurately and sensitively detect oral cancer-related biomarker (ORAOV 1) for the early dia...
Analytical Methods
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A simple fluorescence pyrocatechol-polyethyleneimine detection method for 3-MCPD
A rapid fluorescence detection method was established for 3-monochloropropane-1,2-diol (3-MCPD). The detection system work...
Analytical Methods
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Complexation of gallic acid with calcium-electrochemical, potentiometric, and UV-VIS study
Gallic acid and its metal complexes are good antioxidants that could be used to increase the body’s immune system against ...
Analytical Methods
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Simultaneous Determination of Methyltestosterone and Its Metabolite in Fish by Gas Chromatography-Mass Spectrometry
Methyltestosterone is one of the banned drugs in aquaculture, and it should be monitored in food-producing animals. 17α-me...
Analytical Methods
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Non-immobilized GO-SELEX screening of the aptamer against Cyclosporine A and its application in AuNPs colorimetric aptasensor
Cyclosporine A (CsA) is an immunosuppressive drug that widely used in clinic. Due to its narrow therapeutic window and the...
Analytical Methods
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Rapid purifification of alkylamides from Zanthoxylum bungeanum by medium-pressure liquid chromatography and establishment of a numbness prediction model by electronic tongue
In the present study, an efficient and rapid method for the preparation of high-purity typical alkylamides from Zanthoxylu...
Analytical Methods
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Simultaneous determination of 13 sulfonamides at trace levels in soil by modified QuChERS with HPLC-MS/MS
The pretreatment of samples was vital for enhancing the sensitivity and accuracy of analytical methods. An efficient and s...
Analytical Methods
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Development of split G-quadruplex and DAPI-based fluorescent probe for Hg2+ and Pb2+ ions detection
A novel thymine- and guanine-rich oligonucleotide (ODN-7) was engineered explicitly for the detection of Hg2+ and Pb2+ by ...
Analytical Methods
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Method validation for (ultra)-trace element concentrations in urine for small sample volumes in large epidemiological studies: application to the population-based epidemiological Multi-Ethnic Study of Atherosclerosis (MESA)
Analysis of essential and non-essential trace elements in urine has emerged a valuable tool for assessing occupational or ...
Analytical Methods
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Application Progress of Magnetic Solid-Phase Extraction for Heavy Metal Analysis in Food: A Mini Review
The emerging sample pretreatment technique of magnetic solid-phase extraction (MSPE) has drawn the researchers’ attention ...
Analytical Methods
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Fluorescent assay for acetylcholinesterase activity and inhibitor screening based on the lanthanide organic/inorganic hybrid materials
It is of great significance for the clinical diagnosis of Alzheimer’s disease (AD) to achieve the on-site activity evaluat...
Analytical Methods
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HDBB-based fluorescent probe for the sensitive detection of human serum albumin
The detection of human serum albumin (HSA) in body fluids is of great significance in the biomedical area because HSA in b...
Analytical Methods
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Determination of underivatized chlormequat, fosetyl-aluminium and phosphonic acid residues in maize and soybean by LC-MS/MS
A simple, rapid and sensitive method was developed for the simultaneous determination of chlormequat, fosetyl-aluminium an...
Analytical Methods
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