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Targeted Metabolomics of Nucleotide Intermediates for Biomarker Discovery in Acute Kidney Injury
Acute kidney injury (AKI) is a common syndrome among critically ill patients with high incidence and high mortality, chara...
Establishment of the new dispersive solid phase microextraction method with green adsorbent CaAl-LDH hybrid with g-C 3 N 4 utilised for the determination of Pb 2+ in Instant cup noodles and environmental samples
Adsorbents with a significant adsorption capacity and high selectivity are required to identify and eliminate heavy metal ...
Construction and validation of a method for detecting DPP-IV activity and tissue distribution in C57 mice based on fluorescent probe
Dipeptidyl peptidase-IV (DPP-IV) is critical for drug metabolism and physiological regulation. In terms of species differe...
Analytical methods for glycoRNA detection: A systematic review
Glycosylated RNAs (glycoRNAs) are a groundbreaking discovery in glycobiology, extending the diversity of known glycoconjug...
Establishment and evaluation of the detection method for human adenovirus and its subtypes based on RAA-LFD technology
Abstract: In this research, we developed a rapid assay for detecting human adenovirus (HAdV) and its prevalent subtypes (i...
Ambient Ionization Mass Spectrometry for Rapid Screening of Illegal Adulteration in Traditional Chinese Medicines: A Review
Illegal adulteration of Traditional Chinese Medicines has become a critical global safety concern, driven by the covert ad...
Characterizing Noninvasively Conservation Status of Historical Wet Collections using Spatially Offset Raman Spectroscopy
Fluid-preserved specimens are central to the scientific and cultural value of natural history collections, yet their conse...
Correction: A portable fluorescent aptamer sensor for rapid quantitative detection of Hg2+
Correction for ‘A portable fluorescent aptamer sensor for rapid quantitative detection of Hg2+’ by Jiayi Li et al., Anal. ...
Untargeted UHPLC-Q-Orbitrap Metabolomics Reveals Hormonal Suppression and Candidate Serum Markers as Evidence of Testosterone Misuse in Cattle
The illicit use of androgenic anabolic steroids, such as 17β-testosterone, in food-producing animals poses significant ris...
A novel APE1-assisted cycling amplification for rapid and ultrasensitive SERS detection of TK1 mRNA in human serum
Quantitative mRNA expression levels are essential for differential and clinical diagnoses. In this work, we present an apu...
An Integrated Magnetic-Microfluidic Chemiluminescence Platform for Rapid Quantification of Exosomal miR-21 Associated with Breast Cancer
Accurate quantification of microRNAs (miRNAs) is crucial for early cancer diagnosis, but conventional techniques, such as ...
Hypoxia activated fluorescent probe for specific visualization of mitochondrial dysfunction in tumor
Selectively monitoring the mitochondrial dysfunction and viability of tumor was an important task for the treatment agains...
A novel electrochemical sensor for the analysis of vibegron as a newly approved FDA drug: A rational computational design and cleaning validation application
A novel analytical tool was developed for the assay of the recently approved β3-adrenergic receptor agonist “vibegron”. Th...
Selection of a DNA Aptamer for the Development of an Electrochemical Aptasensor for the Detection of Pb²⁺
In order to develop a simple, highly sensitive and cost-effective electrochemical sensor with high specificity for lead io...
Nanosensors as Diagnostic Tools: Emerging Concepts, Opportunities, and Design Barriers
Nanosensors have become a revolutionary tool, enabling early diagnosis and continuous monitoring of diseases with high acc...
A portable fluorescent aptamer sensor for rapid quantitative detection of Hg2+
Mercury (II) ions (Hg2+) are heavy metals can cause human poisoning, and severe cases can lead to death. Therefore, establ...
Construction of a Colorimetric Glyphosate Detection Platform Based on Peroxidase-like Activity of MOF-818(Cu)
The health risks and environmental safety issues arising from the long-term extensive use of glyphosate have become a glob...
Controlled fabrication of novel magneto-fluorescent encoded microspheres with host-guest structure for simultaneous detection of thyroxine and thyroid stimulating hormone
Simultaneous detection serum thyroxine (T4) and thyroid stimulating hormone (TSH) is essential for diagnosis and monitorin...
Real-time reliable detection of Adrenocorticotropic hormone Using Reduced Graphene Oxide Field-Effect Transistors
Adrenocorticotropic hormone (ACTH), a pivotal regulator in stress response and cortisol production, poses substantial dete...
Development of Highly Sensitive Label-Free Electrochemical Immunosensor for p16INK4a Detection: A Step Toward Early Cervical Cancer Diagnosis
Cervical cancer screening is the key public health approach for secondary prevention of cervical cancer particularly in re...
Spectrofluorimetric Determination of Brexpiprazole via Quenching of Erythrosine B Fluorescence: Optimization using Box-Behnken Design
A simple, rapid and sensitive spectrofluorimetric method was developed and validated for the determination of brexpiprazol...
Development of a new biodetection system independent on known marker molecules by using a novel material for microarrays made from amorphous carbon substrates.
A bio-chip substrate made from amorphous carbon has been successfully developed for an innovative and practical biodetecti...
Development of a NS-CDs/Fluorescein Ratiometric Fluorescent Sensor Integrated Smartphone Platform for Rapid and Specific Detection of Mn(VII) and Captopril
The construction of a ratiometric fluorescent sensor based on nitrogen-doped carbon dots (NS-CDs) and fluorescein was repo...
Primary microplastics in cosmetics: experience in isolation and spectral analysis
Eight samples of personal care and cosmetic products (PCCPs) present on the market were analyzed to isolate and characteri...
Ultra-high performance liquid chromatography tandem mass spectrometry for profiling mercapturic acids in human urine after daily exposure to acrylamide, 3-monochloropropane-1,2-diol and glycidol
The mercapturic acids are critical urinary biomarkers for evaluating the short-term exposure to typical food processing co...
A near-infrared fluorescent probe for detecting Cu²⁺ and its versatile applications
Copper ions (Cu²⁺), although essential for biological systems, pose substantial environmental and health risks at ele...
Cyclodextrin-Based Architectures for Electrochemical Sensing: From Molecular Recognition to Functional Hybrids
This review surveys recent advances in the integration of cyclodextrins (CDs) with diverse materials for electrochemical d...
A stable Zn-coordination polymer for the quantitative and selective detection of biomarker phenylglyoxylic acid in urine
Developing stable sensing materials for the sensitive detection of phenylglyoxylic acid (PGA) in biological sample is pret...
Highly Efficient Electrochemical Detection of H2O2 Utilizing an Innovative Copper Porphyrinic Nanosheet Decorated Bismuth Metal-Organic Framework Modified Electrode
The ability to detect hydrogen peroxide must account for its presence in biological systems. Researchers are highly intere...
An isocratic HPLC-UV method for simultaneous quantification of tizanidine and lidocaine: Application to in vitro release studies of subcutaneous implant
Implantable devices have been widely investigated to improve the treatment of multiple diseases. Even with low drug loadin...
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