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Group 1 innate lymphoid cells and inflammatory macrophages exacerbate fibrosis in creeping fat through IFN-γ secretion
Group 1 innate lymphoid cells and inflammatory macrophages exacerbate fibrosis in creeping fat through IFN-γ secretion
Creeping fat is a characteristic of Crohn's disease and impacts the disease course. We evaluated creeping fat formatio...
Circulating miR-485-3p as a biomarker for VEGF-associated therapeutic response to atezolizumab plus bevacizumab in hepatocellular carcinoma
Circulating miR-485-3p as a biomarker for VEGF-associated therapeutic response to atezolizumab plus bevacizumab in hepatocellular carcinoma
In atezolizumab/bevacizumab (atezo/bev) therapy for unresectable hepatocellular carcinoma (HCC), the tumor immune environm...
Prevalence and risk factors for lymph node metastasis in duodenal neuroendocrine tumors: a systematic review and meta-analysis
Prevalence and risk factors for lymph node metastasis in duodenal neuroendocrine tumors: a systematic review and meta-analysis
Although the status of lymph node metastasis (LNM) is crucial in determining treatment strategy for duodenal neuroendocrin...
Clinical application of targeted α-emitter therapy in gastroenteropancreatic neuroendocrine neoplasms
Clinical application of targeted α-emitter therapy in gastroenteropancreatic neuroendocrine neoplasms
Effective therapeutic strategies for advanced gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) remain challengin...
Educational interventions to enhance support for balancing work and treatment in inflammatory bowel disease patients
Educational interventions to enhance support for balancing work and treatment in inflammatory bowel disease patients
Inflammatory bowel disease (IBD) significantly impacts employment and work productivity, necessitating support for balanci...
Post-marketing surveillance of tofacitinib in patients with ulcerative colitis in Japan: a final report of safety and effectiveness data
Post-marketing surveillance of tofacitinib in patients with ulcerative colitis in Japan: a final report of safety and effectiveness data
We present the final analysis of a tofacitinib post-marketing surveillance (PMS) study in Japanese patients with ulcerativ...
Endoscopic liquid biopsy of bile: superior diagnostic and prognostic performance of bile-derived exosomal miR-21-5p for biliary tract cancers
Endoscopic liquid biopsy of bile: superior diagnostic and prognostic performance of bile-derived exosomal miR-21-5p for biliary tract cancers
Compared to peripheral blood, bile as a microenvironment within the biliary tract is expected to contain a higher concentr...
Identification of novel plasma proteins as promising noninvasive biomarker for early diagnosis and surveillance of pancreatic ductal adenocarcinoma
Identification of novel plasma proteins as promising noninvasive biomarker for early diagnosis and surveillance of pancreatic ductal adenocarcinoma
Although cancer antigen 19–9 (CA 19–9) is the only FDA-approved biomarker for pancreatic ductal adenocarcinoma...
Impact of early aggressive treatment on long-term biochemical marker patterns in inflammatory bowel disease
Impact of early aggressive treatment on long-term biochemical marker patterns in inflammatory bowel disease
The disease course of inflammatory bowel disease (IBD) is highly variable; early and precise identification of patients wi...
Current status and trends in ERCP and post-ERCP pancreatitis in Japan: a nationwide observational study
Current status and trends in ERCP and post-ERCP pancreatitis in Japan: a nationwide observational study
Endoscopic retrograde cholangiopancreatography (ERCP) is indispensable for the management of biliary and pancreatic diseas...
Factors associated with actionable gene aberrations in pancreatic cancer based on the C-CAT database
Factors associated with actionable gene aberrations in pancreatic cancer based on the C-CAT database
Comprehensive genomic profiling (CGP) tests are increasingly used to explore the genomically matched therapies for solid t...
Serum FGF19 combined with GGT and other biomarkers predicted native liver survival following Kasai portoenterostomy in early biliary atresia
Serum FGF19 combined with GGT and other biomarkers predicted native liver survival following Kasai portoenterostomy in early biliary atresia
Accurately predicting the prognosis of biliary atresia (BA) prior to Kasai portoenterostomy (KPE) remains a challenge. The...
Abnormalities of intracellular organelles in metabolic dysfunction-associated steatotic disease
Abnormalities of intracellular organelles in metabolic dysfunction-associated steatotic disease
The concept of metabolic dysfunction-associated steatotic disease (MASLD) is increasingly being recognized. The mechanisms...
An axon guidance-related microRNA panel identifies perivascular plexus local recurrence following curative surgery in patients with pancreatic cancer
An axon guidance-related microRNA panel identifies perivascular plexus local recurrence following curative surgery in patients with pancreatic cancer
Complete oncological local control is essential for a potential cure in patients with pancreatic ductal adenocarcinoma (PD...
External validation of the eCura system and comparison with the W-eCura score for predicting lymph node metastasis after non-curative endoscopic submucosal dissection for early gastric cancer: a multicenter retrospective cohort study
External validation of the eCura system and comparison with the W-eCura score for predicting lymph node metastasis after non-curative endoscopic submucosal dissection for early gastric cancer: a multicenter retrospective cohort study
The eCura system is a widely used risk-scoring model for predicting lymph node metastasis (LNM) after non-curative endosco...
Associations between excessive supragastric belching and esophageal reflux factors in patients with PPI-refractory GERD in Japan
Associations between excessive supragastric belching and esophageal reflux factors in patients with PPI-refractory GERD in Japan
No studies have evaluated the prevalence of supragastric belching (SGB) in Japanese patients with proton pump inhibitor (P...
Genomic profile and clinical features of MSI-H and TMB-high pancreatic cancers: real-world data from C-CAT database
Genomic profile and clinical features of MSI-H and TMB-high pancreatic cancers: real-world data from C-CAT database
Microsatellite instability high (MSI-H) and tumor mutational burden high (TMB-high) pancreatic cancer are rare, and inform...
C-CAT's triumph in gastroenterology: the wisdom of cats is infinitely superior
C-CAT's triumph in gastroenterology: the wisdom of cats is infinitely superior
Department of Hepatology, Osaka Metropolitan University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka, ...
The antiferroptotic effect of indigo on ulcerative colitis
The antiferroptotic effect of indigo on ulcerative colitis
The protective effect of indigo on intestinal epithelial cells remains unclear. Yokote Akihito et al. preliminarily invest...
Characteristics, outcomes, and risk factors of surgery for acute lower gastrointestinal bleeding: nationwide cohort study of 10,342 hematochezia cases
Characteristics, outcomes, and risk factors of surgery for acute lower gastrointestinal bleeding: nationwide cohort study of 10,342 hematochezia cases
Current evidence on the surgical rate, indication, procedure, risk factors, mortality, and postoperative rebleeding for ac...
Reply to “Ferroptosis in the colon epithelial cells as a therapeutic target for ulcerative colitis”
Reply to “Ferroptosis in the colon epithelial cells as a therapeutic target for ulcerative colitis”
Stockwell BR, Friedmann Angeli JP, Bayir H, et al. Ferroptosis: a regulated cell death nexus linking metabolism, redox bio...
Lansoprazole inhibits the development of sessile serrated lesions by inducing G1 arrest via Skp2/p27 signaling pathway
Lansoprazole inhibits the development of sessile serrated lesions by inducing G1 arrest via Skp2/p27 signaling pathway
Although the serrated-neoplasia pathway reportedly accounts for 15–30% of colorectal cancer (CRC), no studies on che...
Reply to ‘C-CAT's triumph in gastroenterology: the wisdom of cats is infinitely superior’
Reply to ‘C-CAT's triumph in gastroenterology: the wisdom of cats is infinitely superior’
We greatly appreciate the Journal of Gastroenterology’s policy of providing an open opportunity to discuss unresolved scie...
The magnetic resonance imaging and age-adjusted matrix metalloproteinase-7 assist the diagnosis of biliary atresia
The magnetic resonance imaging and age-adjusted matrix metalloproteinase-7 assist the diagnosis of biliary atresia
We investigated the utilities of the liver-to-psoas apparent diffusion coefficient ratios (LTPAR) yielded by diffusion-wei...
Three-dimensional chromatin landscapes in hepatocellular carcinoma associated with hepatitis B virus
Three-dimensional chromatin landscapes in hepatocellular carcinoma associated with hepatitis B virus
Three-dimensional (3D) chromatin architecture frequently altered in cancer. However, its changes during the pathogenesis o...
Induction of ferroptosis by photodynamic therapy and enhancement of antitumor effect with ferroptosis inducers
Induction of ferroptosis by photodynamic therapy and enhancement of antitumor effect with ferroptosis inducers
Photodynamic therapy (PDT) is an effective tumor treatment that involves the administration of a photosensitizer to genera...
Marked intestinal trans-differentiation by autoimmune gastritis along with ectopic pancreatic and pulmonary trans-differentiation
Marked intestinal trans-differentiation by autoimmune gastritis along with ectopic pancreatic and pulmonary trans-differentiation
Autoimmune gastritis (AIG) is a prevalent chronic inflammatory disease with oncogenic potential that causes destruction of...
Editorial: Comparisons of COVID-19-related disturbance in diagnosis of esophagogastric cancer between the Netherlands and Japan
Editorial: Comparisons of COVID-19-related disturbance in diagnosis of esophagogastric cancer between the Netherlands and Japan
Rutter MD, Brookes M, Lee TJ, et al. Impact of the COVID-19 pandemic on UK endoscopic activity and cancer detection: A nat...
MGAT5/TMEM163 variant is associated with prognosis in ursodeoxycholic acid-treated patients with primary biliary cholangitis
MGAT5/TMEM163 variant is associated with prognosis in ursodeoxycholic acid-treated patients with primary biliary cholangitis
Primary biliary cholangitis (PBC) is a chronic immune-mediated liver disease. Previous genome-wide meta-analysis has ident...
Clinicopathologic differences of gastric neoplasms between Helicobacter pylori-infected and -naïve patients: a multicenter retrospective analysis
Clinicopathologic differences of gastric neoplasms between Helicobacter pylori-infected and -naïve patients: a multicenter retrospective analysis
The incidence of gastric neoplasms in Helicobacter pylori (Hp)-naïve patients has recently increased due to a remarka...
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